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Elsevier

  • Microbiology and Molecular Diagnosis in Pathology

    A Comprehensive Review for Board Preparation, Certification and Clinical Practice
    • 1st Edition
    • Audrey Wanger + 5 more
    • English
    Microbiology and Molecular Diagnosis in Pathology: A Comprehensive Review for Board Preparation, Certification and Clinical Practice reviews all aspects of microbiology and molecular diagnostics essential to successfully passing the American Board of Pathology exam. This review book will also serve as a first resource for residents who want to become familiar with the diagnostic aspects of microbiology and molecular methods, as well as a refresher course for practicing pathologists. Opening chapters discuss issues of laboratory management, including quality control, biosafety, regulations, and proper handling and reporting of laboratory specimens. Review chapters give a quick overview of specific clinical infections as well as different types of bacteria, viruses, fungal infections, and infections caused by parasites. Following these, coverage focuses on diagnostic tools and specific tests: media for clinical microbiology, specific stains and tests for microbial identifications, susceptibility testing and use of antimicrobial agents, tests for detecting antibodies, antigens, and microbial infections. Two final chapters offer overviews on molecular diagnostics principles and methods as well as the application of molecular diagnostics in clinical practice.
  • Piperidine-Based Drug Discovery

    • 1st Edition
    • Ruben Vardanyan
    • English
    Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives. Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. The most commonly used heterocycle among US FDA approved pharmaceuticals, Piperidine is an extremely important building block in the synthesis of medicinal agents. This heterocycle and its derivatives exhibit a number of important functionalities and have been employed variously as CNS modulators, antiaggregants, anticoagulants, antihistamines, anti-cancer drugs and analgesics.
  • Early Childhood Mental Health: Empirical Assessment and Intervention from Conception through Preschool, An Issue of Child and Adolescent Psychiatric Clinics of North America

    • 1st Edition
    • Volume 26-3
    • Mini Tandon
    • English
    This issue of Child and Adolescent Psychiatric Clinics, edited by Dr. Mini Tandon, will cover a broad range of topics in Early Childhood Mental Health. Subjects discussed include, but are not limited to: Newborns, preschoolers, Internalizing Disorders, ADHD and the Externalizing Disorders, Trauma, Sleep Disorders, Attachment issues, Autism, and Feeding Disorders, among others.
  • Evidence-based Pediatric Dentistry, An Issue of Dental Clinics of North America

    • 1st Edition
    • Volume 61-3
    • Donald L. Chi
    • English
    This issue of Dental Clinics of North America focuses on Evidence-based Pediatric Dentistry, and is edited by Dr. Donald Chi. Articles will include: Prenatal maternal factors, intergenerational transmission of disease, and child oral health outcomes; Evidence-based Medicaid policies and research use; Social determinants of children’s oral health; Pediatric behavioral oral health interventions; Pediatric social oral health interventions; Pediatric workforce issues; Pediatric-focused interprofessional interventions; Acculturation and pediatric minority oral health interventions; Interventions focusing on children with special health care needs; Genetics and pediatric dental caries; Oral health interventions during pregnancy; Topical fluoride hesitancy, and more!
  • Disease Prevention, An Issue of Medical Clinics of North America

    • 1st Edition
    • Volume 101-4
    • Michael P. Pignone + 1 more
    • English
    This issue of Medical Clinics, guest edited by Drs. Michael P. Pignone and Kirsten Bibbins-Domingo, is devoted to Disease Prevention. Articles in this issue address prevention for various diseases, including: Breast Cancer; Cervical Cancer; Colorectal Cancer; Lung Cancer; Prostate Cancer; and Screening for Depression. Lipids, CV Risk Assessment, Blood Pressure, and Aspirin for Primary Prevention will also be addressed.
  • Desalination Sustainability

    A Technical, Socioeconomic, and Environmental Approach
    • 1st Edition
    • Hassan Arafat
    • English
    Desalination Sustainability: A Technical, Socioeconomic, and Environmental Approach presents a technical, socioeconomical, and environmental approach that guides researchers and technology developers on how to quantify the energy efficiency of a proposed desalination process using thermodynamics-based tools. The book offers the technical reader an understanding of the issues related to desalination sustainability. For example, technology users, such as public utility managers will gain the ability and tools to assess whether or not desalination is a good choice for a city or country. Readers will learn new insights on a clear and practical methodology on how to probe the economic feasibility of desalination using simple and effective tools, such as levelized cost of water (LCOW) calculation. Decision-makers will find this book to be a valuable resource for the preliminary assessment of whether renewable-powered desalination is a good choice for their particular setting.
  • Orthobiologics, An Issue of Orthopedic Clinics

    • 1st Edition
    • Volume 48-3
    • Frederick M. Azar + 6 more
    • English
    This issue of Orthopedic Clinics focuses on Orthobiologics. Article topics include: Does Prior Cartilage Restoration Impact Outcomes Following Knee Arthroplasty?; Clinical Applications of Tissue Engineering in Joint Arthroplasty: Current Concepts Update; Usage of Bone Graft Substitutes; Bone morphogenetic protein; Role of Bone Marrow Aspirate in Orthopaedic Trauma; Orthobiologics in Pediatric Sports Medicine, and more!
  • Articular Cartilage, An Issue of Clinics in Sports Medicine

    • 1st Edition
    • Volume 36-3
    • Eric McCarty
    • English
    This issue of Clinics in Sports Medicine, edited by Eric McCarty, will cover a variety of useful topics related to Articular Cartilage. Articles include, but are not limited to: Basic science of articular cartilage; Non-operative options for management of articular cartilage disease; Biologic options for articular cartilage wear; Management of OCD lesions of the Knee; Elbow and Ankle, Microfracture; Osteochondral Autograft; Allografts; Autologous Chondrocytes and Next Generation Matrix based Autologous Chondrocyte Implantation; Management and surgical options for articular defects in the shoulder; and Management and surgical options for articular defects in the hip, among others.
  • Burn Care: Rescue, Resuscitation, and Resurfacing, An Issue of Clinics in Plastic Surgery

    • 1st Edition
    • Volume 44-3
    • C. Scott Hultman + 1 more
    • English
    This issue of Clinics in Plastic Surgery, guest edited by Drs. Charles Scott Hultman and Michael W. Neumeister, is devoted to Burn Care: Rescue, Resuscitation, Resurfacing. Articles in this comprehensive issue include: Lessons Learned from Major Disasters: From Cocoanut Grove to 9/11; Disaster Preparedness and Response in the 21st Century; Prevention, Advocacy, Legislation; 7 Habits of Highly Effective Teams:Integrating the Workforce; Financial Impact of Burns; Innovations in Burn Wound Assessment and Care; Hemodynamic Monitoring and Resuscitation; Management of Pulmonary Failure: From the VDR to ECMO; Infection Control: Iimmunosuppression and Management of HAIs; Neuro ICU and Perioperative Sedation/Analgesia; Nutrition, Metabolism, Endocrine; Patient Safety in Burn Patients: From the ICU to Rehab; Dermatologic Emergencies and the Role of the Burn Center; Pediatric Burn Care; Timing and Type of Excision:EBM Guidelines; Skin Substitutes and Bioscaffolds: Temporary and Permanent Coverage; Tissue Engineering and Stem Cells: Regeneration of the Skin and its Contents; Chemical, Electrical, and Radiation Injuries; Perineal Burns and Child Abuse; Negative Pressure Wound Therapy; Chronic Burn Wounds: HBO, Growth Factors, Marjolin's; and Acute Management of Hand Burns.
  • New Directions in Barrett's Esophagus, An Issue of Gastrointestinal Endoscopy Clinics

    • 1st Edition
    • Volume 27-3
    • Nicholas J. Shaheen
    • English
    Dr. Shaheen's issue of Gastrointestinal Endoscopy Clinics of North America addresses the current thinking and clinical decision making surrounding endoscopy for Barrett's Esophagus. Expert authors have contributed articles on the following topics: The Troublesome Epidemiology of Barrett’s Esophagus and Esophageal Adenocarcinoma; Who Deserves Endoscopic Screening for Esophageal Neoplasia; Alternatives to Traditional per oral Endoscopy for Screening; Effectiveness and Cost-Effectiveness of Endoscopic Screening and Surveillance; The Role of Adjunct Imaging in Endoscopic Detection of Dysplasia; Beyond Dysplasia Grade: The Role of Biomarkers in Stratifying Risk; Management of Nodular Neoplasia in Barrett’s Esophagus: Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection; EUS and Management of Superficial Esophageal Neoplasia; Radiofrequency Ablation of Barrett’s Esophagus: Patient Selection, Preparation, and Performance; Radiofrequency Ablation of Barrett’s Esophagus: Efficacy, Complications, and Durability; Cryotherapy of Barrett’s Esophagus; Care of the Post-Ablation Patient: Surveillance, Acid Suppression and Treatment of Recurrence; and Surgical Management of Superficial Esophageal Neoplasia. Readers will come away with the knowledge to diagnose and treat neoplasia and Barrett's Esophagus using the latest techniques.