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Elsevier

Elsevier

  • Polymer-Protein Conjugates

    From Pegylation and Beyond
    • 1st Edition
    • Gianfranco Pasut + 1 more
    • English
    Polymer–Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers design new projects by taking into account the latest innovations for safe and site selective polymer conjugation to proteins. PEG has been the gold standard and likely will play this role for many years, but alternatives are coming into the market, some of which have already been launched. After five decades of improvements, the ideas in this book are entering into a new era of innovation because of the advances in genetic engineering, biochemistry and a better understanding of the results from clinical use of PEG conjugates in humans.

  • Green Sustainable Process for Chemical and Environmental Engineering and Science

    Supercritical Carbon Dioxide as Green Solvent
    • 1st Edition
    • Inamuddin + 2 more
    • English
    Green Sustainable Processes for Chemical and Environmental Engineering and Science: Supercritical Carbon Dioxide as Green Solvent provides an in-depth review on the area of green processes for the industry, focusing on the separation, purification and extraction of medicinal, biological and bioactive compounds utilizing supercritical carbon dioxide as a green solvent and their applications in pharmaceuticals, polymers, leather, paper, water filtration, textiles and more. Chapters explore polymerization, polymer composite production, polymer blending, particle production, microcellular foaming, polymer processing using supercritical carbon dioxide, and a method for the production of micro- and nano-scale particles using supercritical carbon dioxide that focuses on the pharmaceutical industry. A brief introduction and limitations to the practical use of supercritical carbon dioxide as a reaction medium are also discussed, as are the applications of supercritical carbon dioxide in the semiconductor processing industry for wafer processing and its advantages and obstacles.

  • Essentials of Osborn's Brain

    A Fundamental Guide for Residents and Fellows
    • 1st Edition
    • Anne G. Osborn
    • English
    Designed to facilitate easier understanding of a complex subject, Essentials of Osborn’s Brain: A Fundamental Guide for Residents and Fellows is a highly practical guide to neuroradiology by world-renowned expert Dr. Anne G. Osborn. This concise text is derived from Osborn's Brain, second edition, and contains the essential must-know information critical for residents and fellows in radiology, neuroradiology, and neurosurgery—all in a format that's ideal for study and daily reference.

  • Immunology Laboratory Testing,An Issue of the Clinics in Laboratory Medicine

    • 1st Edition
    • Volume 39-4
    • Vinay Subash Mahajan
    • English
    This issue of Clinics in Laboratory Medicine, guest edited by Dr. Vinay Subhash Mahajan, will focus on Immunology Laboratory Testing. Topics include, but are not limited to, Analysis of proteins and immunoglobulins in the clinical immunology laboratory; Antinucl... antibody tests; Serological diagnosis of rheumatoid arthritis; ANCA; Anti-phospholipid antibodies; Diagnostic pitfalls in autoantibody testing; Analysis of the complement pathway; Flow cytometric analysis of immune cell subsets; Testing of cellular immune function in immunodeficiencies; ... allergy testing; Evaluation of the immune response in transplantation; Lab... testing in the context of biologics and cellular therapies; Testing immune-related adverse-events in cancer immunotherapy; Molec... diagnosis of inherited immune disorders; and Future of immunology lab testing.

  • Spinal Cord Injury (SCI) Repair Strategies

    • 1st Edition
    • Giuseppe Perale + 1 more
    • English
    Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair.

  • Ecosystem Service Potentials and Their Indicators in Postglacial Landscapes

    Assessment and Mapping
    • 1st Edition
    • Andrzej Affek + 7 more
    • English
    Ecosystem Service Potentials and Their Indicators in Postglacial Landscapes: Assessment and Mapping provides valuable guidance for anyone involved with ecosystem service potential monitoring, use and management—from landscape ecologists and environmental managers, to policymakers and environmental economists. The book highlights effective measurement tools for evaluating the overall potential of ecosystem services from multiple perspectives. Beginning with an introduction to ecosystem services and the theoretical assumptions and objectives associated with their assessment, the book goes on to outline interdisciplinary methods of evaluation and analysis that are fully supported and illustrated throughout using an insightful case study focused on Wigry National Park. A range of different spatial reference units are also discussed, followed by chapters on both analytical and synthetic approaches to identifying service supply potential. In addition, the use of services and the impact of these uses on the assessment of potential is included, along with a discussion of the future shape of ecosystem service assessment.

  • Emerging and Re-Emerging Infectious Diseases , An Issue of Infectious Disease Clinics of North America

    • 1st Edition
    • Volume 33-4
    • Alimuddin Zumla + 1 more
    • English
    In consultation with Consulting Editor, Dr. Helen Boucher, Drs. Zumla and Hui have assembled an excellent clinical overview of the current priorities in treating emerging and re-emerging infections. A number of landmark events have occurred in the area of epidemic infections. The frequency and diversity of serious and drug/antibiotic-resi... infections are increasing. New and re-emerging infectious disease outbreaks continue to cause much human suffering and loss of life worldwide. Current priority infectious diseases concerns that threaten global health security are covered in this issue: Cholera; Typhoid and antibiotic-resistant strains; multi—drug-resistant Tuberculosis; Invasive Meningococcal disease; Invasive Pneumococcal disease; antibiotic-resistant bacterial, viral, and protozoal infections; diphtheria; pandemic influenza; MERS; SARS; Measles; viral haemorrhagic fevers; wild-type Polio virus; Zika; antibiotic-resistant sexually transmitted diseases; drug-resistant Malaria; ARV-resistant HIV; and fungal infections. This issue’s clinical review articles, written by authoritative and renowned experts in the area would, have broad appeal, from general internists to respiratory specialists. It should also prove interesting to infectious diseases specialists, health practitioners in the tropics, pulmonologists, internal medicine fellows, family physicians, and health-care policy makers in the west and developing countries. Medical students, postgraduates, and research fellows (both undergraduates and postgraduates) will also find this issue useful and to be a updated reference in the field of respiratory medicine, tropical medicine, and infectious diseases.

  • Population Health

    • 1st Edition
    • Volume 48-4
    • Devdutta Sangvai + 1 more
    • English
    This issue of Primary Care: Clinics in Office Practice, guest edited by Drs. Anthony J. Viera and Devdutta Sangvai, is devoted to Population Health. Articles in this issue include: What is Population Health?; Measuring Health; Prevention as a Population Health Strategy; Value-Based Care; The Business Case for Population Health Management; Primary Care Transformation; Patient Engagement; Quality Improvement Principles and Practice; Lean Management; Population Health and AMCs: High cost meets high efficiency; Models of Population Health Management; Tools for Population Health Management; Clinically Integrated Networks; Assessing and Addressing Social Determinants of Health; and Population Health Policies.

  • Endocrine Hypertension,An Issue of Endocrinology and Metabolism Clinics

    • 1st Edition
    • Volume 48-4
    • Amir Hekmat Hamrahian
    • English
    This issue of Endocrinology and Metabolism Clinics, Guest Edited by Dr. Amir Hekmat Hamrahian, will focus on Endocrine Hypertension. Topics include, but are not limited to, Cardiovascular Risks and Organ Damage in Secondary Hypertension, Adrenal Imaging and Adrenal Incidentalomas, Diagnosis and Management of Primary aldosteronism, Low Renin Hypertension, Cushing Syndrome, Pheochromocytoma/Par... Paroxysmal Hypertension, Renovascular Hypertension, Hypertension and Acromegaly/GH Excess, Monogenic Forms of Hypertension, Resist... Hypertension, Endocr... Hypertension in Children, Evaluation and Management of Endocrine Hypertension During Pregnancy, and Adrenal Venous Sampling.

  • Current concepts of treatment of Metatarsalgia, An issue of Foot and Ankle Clinics of North America

    • 1st Edition
    • Volume 24-4
    • Gaston A. Slullitel
    • English
    This issue of Foot and Ankle Clinics, guest edited by Dr. Gaston Slullitel, will discuss Current Concepts of Treatment of Metatarsalgia. Under the guidance of long-time series Consulting Editor Dr. Mark Myerson, Dr. Slullitel and his contributing authors will explore topics of interest for practitioners in the field. Articles include, but are not limited to: the role of First ray insufficiency in the development of metatarsalgia; Current evidence in surgical treatment for metatarsalgia; Evolution of The Weil Osteotomy; State of the Art in Lesser MTPJ Instability; MIS options for Metatarsalgia Treatment; Gastroc recession in the setting of Metarsalgia; Freiberg's infraction: surgical options; Resection arthroplasty; and Brachymetatatarsia, among others.

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