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Elsevier

Elsevier Science

  • Biotechnology Annual Review

    • 1st Edition
    • Volume 9
    • M.R. El-Gewely
    • English
    It is an exciting time to follow the new developments in the field of biotechnology and its wider applications in the different areas. The whole genomes of over 1000 viruses and over 100 microbes can now be found in Entrez Genome. The genomes represent both completely sequenced organisms and those for which sequencing is still in progress. The three main domains of life - bacteria, archaea, and eukaryota - are represented, as well as many viruses and organelles. The exponential increase of the sequence data lead to the development of the new "Bioinformatics" field in order to attempt making sense, at least biological sense, out of all the new and fast data.It will take also other techniques such as "functional genomics" to link the gap between a specific phenotype or a treatment and a gene sequence. Functional genomics tools are therefore important for the accurate molecular diagnosis/prognosis, target discovery validation needed for drug development and novel targets for antibiotics development. Functional genomics are also important for the confirmation of therapy in pharmacogenomics studies. Biotechnology is in many respects shaping our life and affecting our means of production and the creation of jobs. Progress in the applications of biotechnology depends on a wide base of basic as well as applied sciences. The output of biotechnology has already proved itself in many diverse fields from health tobiomining and from agriculture to enzyme "breeding". It is therefore difficult to follow all of the current as well as the potential applications of biotechnology.The objective of the Biotechnology Annual Review series is to attempt to provide readers with the needed indepth knowledge, by reviewing specific topics in biotechnology in each issue. The philosophy behind this series is to encourage good reviews to make it easier for readers to keep in touch with progress and applications of biotechnology. Reviews on topics related to regulatory affairs, social impact of biotechnology, biodiversity, biosafety, public acceptance and patent issues are also encouraged.

  • Lab-on-a-Chip

    Miniaturized Systems for (Bio)Chemical Analysis and Synthesis
    • 1st Edition
    • Edwin Oosterbroek + 1 more
    • English
    In the past ten years there has been a rapid growth of the research and application area known as Lab-on-a-Chip. After an initial focus on electrokinetic separation techniques on chip, the scope of the field has widened to include topics like microfluidics, DNA analysis, cell analysis, microreactors and mass spectrometer interfacing. As well as the analytical chemistry community, synthetic chemists, chemical engineers, biochemists and biomedical engineers are now also becoming more and more interested in using new micro- and nanotechnological techniques. This first Lab-on-a-Chip book contains a broad collection of papers on microtechnology, microfluidics, analytical methods and applications. All contributions are written by leading researchers in their respective fields, and provide new scientists with an overview of the field, to make him/her aware of the enormous opportunities offered by modern technology. The work presented in this book will definitely stimulate readers to new ideas and concepts, and lead to further innovations in this area.

  • Wear of Materials

    14th International Conference
    • 1st Edition
    • Peter J. Blau
    • R G Bayer
    • English
    The 14th International Conference on Wear of Materials took place in Washington, DC, USA, 30 March - 3 April 2003. These proceedings contain over two-hundred peer reviewed papers containing the best research, technical developments and engineering case studies from around the world. Biomaterials and nano-tribology receive special attention in this collection reflecting the general trends in the field. Further highlights include a focus on the new generation of instrumentation to probe wear at increasingly small scales. Approximately ninety communications and case studies, a popular format for the academic community have also been included, enabling the inclusion of the most up-to-date research.

  • Elsevier's Dictionary of Acronyms, Initialisms, Abbreviations and Symbols

    • 2nd Edition
    • Fioretta. Benedetto Mattia
    • English
    The dictionary contains an alphabetical listing of approximately 30,000 (thirty thousand) acronyms, initialisms, abbreviations and symbols covering approximately 2,000 fields and subfields ranging from Pelagic Ecology to Anthrax Disease, Artificial Organs to Alternative Cancer Therapies, Age-related Disorders to Auditory Brainstem Implants, Educational Web Sites to Biodefense, Biomedical Gerontology to Brain Development, Cochlear Implants to Cellular Phones, Constructed Viruses to Copper Metabolism, Drug Discovery Programs to Drug-resistant Strains, Eugenics to Epigenetics, Epilepsy Drugs to Fertility Research, Genetically Modified Foods/Crops to Futuristic Cars, Genetic Therapies to Glycobiology, Herbicide-tolerant Crops to Heritable Disorders, Human Chronobiology to Human gene Therapies, Immunization Programs to Lunar Research, Liver Transplantation to Microchip Technology, Mitochondrial Aging to Molecular Gerontology, Neurodegenerative Diseases to Neuropsychology of Aging, Neurosurgery to Next Generation Programs, Obesity Research to Prion Diseases, Quantum Cryptography to Reemerging Diseases, Retinal Degeneration to Rice Genome Research, Social Anthropology to Software Development, Synchrotron Research to Vaccine Developments, Remote Ultrasound Diagnostics to Water Protection, Entomology to Chemical Terrorism and hundreds of others, as well as abbreviations/acrony... relating to European Community and U.S., Japanese and International Programs/Projects/In... from year 2000 up to 2010 as well as World Bank Programs.

  • Wave Energy Conversion

    • 1st Edition
    • Volume 6
    • John Brooke
    • English
    Wave energy, together with other renewable energy resources is expected to provide a small but significant proportion of future energy requirements without adding to pollution and global warming. This practical and concise reference considers alternative application methods, explains the concepts behind wave energy conversion and investigates wave power activities across the globe.

  • Bridging Hippocrates and Huang Ti, Volume 1

    A Comparative Thesaurus of Traditional Chinese and Western Urology, Andrology and Sexology
    • 1st Edition
    • P. Marandola + 2 more
    • English
    Western Medicine as seen today has a strong scientific basis in its development. The pathogenesis of most diseases and their symptomatology and physical signs are well studied and understood. The management of patients is based on firm understanding of these disease processes. In contrast, Traditional Chinese Medicine came about through the experience of many generations of practitioners over thousands of years. Undoubtedly, many of these treatments have proved to be effective in their own way, however, firm scientific basis is still lacking.While most Western Medicine advocates control of disease by eradication of pathogens and surgical removal of diseased organs as in the case of cancer, Traditional Chinese Medicine seeks to improve resistance against disease. There is probably a great wealth of therapeutic value in Traditional Chinese Medicine, which has not been discovered or explored fully. By combining the knowledge of both Western and Traditional Chinese Medicine, one might be able to improve the results of efficacy of treatments and the survival of patients. The integration of Medicine from East and West will take time to evolve and will need interested physicians from different parts of the world to work closely together to realize such a possibility.This book is an attempt to bridge the medical world of two great and ancient civilizations in their approach to the treatment of disease. It is informative with a detailed account of the history of medical development. It is highly recommended for those medical practitioners from both East and West who are interested to explore alternative medicine and research new areas of the medical frontier.

  • Sedimentary Processes: Quantification Using Radionuclides

    • 1st Edition
    • Volume 5
    • J. Carroll + 1 more
    • English
    The advent of radionuclide methods in geochronology has revolutionized our understanding of modern sedimentary processes in aquatic systems. This book examines the principles of the method and its use as a quantitative tool in marine geology, with emphasis on the Pb-210 method. The assumptions and consequences of models and their behaviour are described providing the necessary background to assess the advantages and trade-offs involved when choosing a particular model for application. One of the purposes of this volume is to disentangle the influences of complicating factors, such as sediment flux variations, post-depositional diffusion of radionuclides, and bio-irrigation of sediments, to arrive at sediment ages and to properly assess the attendant data uncertainty. Environmental impacts of chemical, nuclear, or other waste material are of concern in a variety of areas around the world today. A number of relevant examples are included, demonstrating how dating models are useful for determining sources of contaminants and interpreting their influence on the environment.The book is set at a level so that an able student or professional should have no difficulty in following the procedures and methods developed. Each chapter includes case histories showing the strengths and weaknesses of a given procedure with respect to a data example. Included with this volume is the computer source code of a new generation of modelling tools based on inverse numerical analysis techniques. This first generation of the modelling tool is included, along with detailed instructions and examples for its use, in an appendix.

  • Stable-Nanoemulsions

    Self-Assembly in Nature and Nanomedicine
    • 1st Edition
    • Volume 19
    • Joseph D'Arrigo
    • English
    This title is a greatly expanded and updated second edition of the original volume published by Elsevier in 1986. New material has been integrated with the original content in an organized and comprehensive manner. Five new chapters have been included, which review over one and a half decades of research into lipid-coated microbubbles (LCM) and their medical applications. The new chapters contain much experimental data, which is examined in detail, along with relevant current literature. This current edition builds on the original work in effectively filling the gap in the market for a comprehensive account of the surfactant stabilization of coated microbubbles.

  • Siberian river run-off in the Kara Sea

    Characterisation, quantification, variability, and environmental significance
    • 1st Edition
    • Volume 6
    • R. Stein + 4 more
    • English
    Within the joint German-Russian research project "Siberian River Run-off (SIRRO)" multidisciplinary studies were carried out in the Ob and Yenisei estuaries and adjacent southern Kara Sea (Arctic Ocean). The overall goal of the project was to extend knowledge on understanding the freshwater and sediment input by the major Siberian rivers and its impact on the environments of the inner Kara Sea. The main results of oceanographical, biological, geochemical, geological and modelling studies are presented in four main chapters:(A) Modern Discharge: Data and modelling; (B) Discharge and biological processes, (C) Discharge and organic carbon cycle, and (D) Discharge and sediment records.

  • Inositol Phospholipid Metabolism and Phosphatidyl Inositol Kinases

    • 1st Edition
    • Volume 30
    • A. Kuksis
    • English
    This book offers a wide ranging and review of cutting edge developments along with tried and tested methods for isolation, resolution and quantification of inositol phospholipids and inositol polyphosphates in both cells and tissues. It includes detailed and rigorous methodology for identification of molecular species of inositol phospholipids, including their phosphates and glycans, with numerous examples of specific applications. Wherever available, both chromatographic and mass spectrometricevidenc... is presented for specific phospholipid involvement in the biochemical transformations accompanying metabolic signalling events and, where possible, controversies have been resolved on basis of analytical ambiguity. The review of the lipidanalyses extends to products of phosphatidylinositol kinases, phosphatases and lipases. A general review chapter is included on metabolic signalling with special emphasis on the lipid products of 3-kinases. In view of the general lack of commercially available standards for inositol phospholipids and inositol phosphates, the book concludes with a chapter on the preparation and collection of chromatographic and mass spectrometric proof of their purity and identity.This book complements recent books and reviews on the mechanisms metabolic signalling, receptor binding and the polypeptide structure of the proteins involved in the various signalling pathways. It also complements those texts that deal exclusively with the chemical synthesis of the phosphatidylinositol... and their polyphosphates and glycans.

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