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Elsevier

Elsevier Science

  • GABA and the Basal Ganglia

    • 1st Edition
    • Volume 160
    • J. M. Tepper + 2 more
    • English
    Over the past 25 years the amount of data pertaining to the GABAergic function in the basal ganglia has increased dramatically. GABA and the Basal Ganglia - From Molecules to Systems is a comprehensive review of the current state-of-the-art of knowledge about the neuroanatomy, neuropharmacology and neurophysiology of the basal ganglia, focusing on its GABAergic microcircuitry. It serves as a complete reference to the body of knowledge about the basal ganglia, its constituent neurons, and their interconnections. This volume is designed to serve as a convenient all-in-one review and reference for experienced basal ganglia researchers as well as an introduction to the functional organization of the basal ganglia and its GABAergic circuitry for students and researchers new to the field.

  • Fault Detection, Supervision and Safety of Technical Processes 2006

    A Proceedings Volume from the 6th IFAC Symposium SAFEPROCESS 2006, Aug 30 - Sep1, 2006, Beijing, P.R. China
    • 1st Edition
    • Volume 1
    • Hong-Yue Zhang
    • English

  • Nonlinear Dynamics of Rotating Shallow Water: Methods and Advances

    • 1st Edition
    • Volume 2
    • English
    The rotating shallow water (RSW) model is of wide use as a conceptual tool in geophysical fluid dynamics (GFD), because, in spite of its simplicity, it contains all essential ingredients of atmosphere and ocean dynamics at the synoptic scale, especially in its two- (or multi-) layer version. The book describes recent advances in understanding (in the framework of RSW and related models) of some fundamental GFD problems, such as existence of the slow manifold, dynamical splitting of fast (inertia-gravity waves) and slow (vortices, Rossby waves) motions, nonlinear geostrophic adjustment and wave emission, the role of essentially nonlinear wave phenomena. The specificity of the book is that analytical, numerical, and experimental approaches are presented together and complement each other. Special attention is paid on explaining the methodology, e.g. multiple time-scale asymptotic expansions, averaging and removal of resonances, in what concerns theory, high-resolution finite-volume schemes, in what concerns numerical simulations, and turntable experiments with stratified fluids, in what concerns laboratory simulations. A general introduction into GFD is given at the beginning to introduce the problematics for non-specialists. At the same time, recent new results on nonlinear geostrophic adjustment, nonlinear waves, and equatorial dynamics, including some exact results on the existence of the slow manifold, wave breaking, and nonlinear wave solutions are presented for the first time in a systematic manner.

  • Cork: Biology, Production and Uses

    • 1st Edition
    • Helena Pereira
    • English
    This comprehensive book describes cork as a natural product, as an industrial raw-materials, and as a wine bottle closure. From its formation in the outer bark of the cork oak tree to the properties that are of relevance to its use, cork is presented and explained including its physical and mechanical properties. The industrial processing of cork from post-harvest procedures to the production of cork agglomerates and composites is described. Intended as a reference book, this is the ideal compilation of scientific knowledge on state-of-the-art cork production and use.

  • Dislocations in Solids

    • 1st Edition
    • Volume 13
    • English
    Dislocations are lines of irregularity in the structure of a solid analogous to the bumps in a badly laid carpet. Like these bumps they can be easily moved, and they provide the most important mechanism by which the solid can be deformed. They also have a strong influence on crystal growth and on the electronic properties of semiconductors.

  • Analysis of Cosmetic Products

    • 1st Edition
    • Amparo Salvador + 1 more
    • English
    Analysis of Cosmetic Products advises the reader from an analytical chemistry perspective on the choice of suitable analytical methods for production monitoring and quality control of cosmetic products. In the format of an easy-to-understand compendium of published literature on the subject, this book will enable people working in the cosmetic industry or in research laboratories to:* become familiar with the main legislative and analytical literature on this subject and * learn about and choose suitable analytical procedures for production monitoring and control of cosmetic products, according to their composition.The first section of Analysis of Cosmetic Products covers various definitions and concepts relating to cosmetic products, current legislation in different countries and specific legislation on ingredients. The central body of the book addresses analytical methods for monitoring and quality control of cosmetic products with the fundamental objective being to enable reader's access to scientific reviews carried out by experts in analytical chemistry. The final section contains a small review of the alternative methods to using animals for cosmetic product evaluation.

  • Introduction to Diffusion Tensor Imaging

    • 1st Edition
    • Susumu Mori
    • English
    The concept of Diffusion Tensor Imaging (DTI) is often difficult to grasp, even for Magnetic Resonance physicists. Introduction to Diffusion Tensor Imaging uses extensive illustrations (not equations) to help readers to understand how DTI works. Emphasis is placed on the interpretation of DTI images, the design of DTI experiments, and the forms of application studies. The theory of DTI is constantly evolving and so there is a need for a textbook that explains how the technique works in a way that is easy to understand - Introduction to Diffusion Tensor Imaging fills this gap.

  • Eye Movements

    A Window on Mind and Brain
    • 1st Edition
    • Roger PG van Gompel
    • English
    Eye-movement recording has become the method of choice in a wide variety of disciplines investigating how the mind and brain work. This volume brings together recent, high-quality eye-movement research from many different disciplines and, in doing so, presents a comprehensive overview of the state-of-the-art in eye-movement research. Sections include the history of eye-movement research, physiological and clinical studies of eye movements, transsaccadic integration, computational modelling of eye movements, reading, spoken language processing, attention and scene perception, and eye-movements in natural environments.

  • Radicals for Life

    The Various Forms of Nitric Oxide
    • 1st Edition
    • Ernst van Faassen + 1 more
    • English
    Radicals for Life: the Various Forms of Nitric Oxide provides an up-to-date overview of the role of nitrosocompounds and nitrosyl-iron complexes in physiology. Nitrosocompounds can be considered as stabilised forms of nitric oxide, one of the most important regulatory molecules in physiology today. Many nitrosocompounds share some of the physiological functions of nitric oxide, and may be formed inside living organisms. This is the first book to be published that is dedicated to the role of such nitrosocompounds in physiology, with particular emphasis on the nitrosocompounds that are endogenously formed in higher organisms and humans. Points of discussion include: physical and chemical properties of the compounds, the main chemical pathways in vivo, as well as the physiological effects that have been recognised to date. Each of the nineteen chapters is written by distinguished specialists in the field, well known for their original and important contributions to the subject. Also included are results from a wide range of studies in vitro, in cell cultures, animal models and human volunteers. Examples of alternative forms of nitric oxide, with special emphasis on their protective role against widespread human diseases like atherosclerosis, Alzheimer's disease, diabetes, sexual dysfunction, and renal insufficiency to stroke and ischemia are also included.

  • Quantitative Structure-Activity Relationships (QSAR) for Pesticide Regulatory Purposes

    • 1st Edition
    • Emilio Benfenati
    • English
    Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes stems from the experience of the EC funded project DEMETRA. This project combined institutes involved in the regulatory process of pesticides, industries of the sector and scientists to develop and offer original software for the prediction of ecotoxicity of pesticides. Then to be used within the dossier preparation for pesticide registration. The basis of this book is more than three-years of research activities, discussions, studies and successful models. This experience represents a useful example not only for the case of pesticides, but also for the prediction of ecotoxicity and toxicity in general. QSAR is used to link a given property of a chemical compound with some features related to its structure. The theoretical toxicological, chemical and information technology aspects will be treated considering the regulatory issues. Innovative hybrid systems will be described, for the toxicity prediction of pesticides and related compounds, directly useful for pesticide evaluation within the Dossier preparation for pesticide registration. Five endpoints will also be discussed, addressing issues as standardisation, verification, validation, accessibility, reproducibility.The driving force for Quantitative Structure-Activity Relationship (QSAR) for Pesticide Regulatory Purposes is that all the issues of concern for end-users are analysed, discussed and solutions proposed further. An innovative feature is that, in order to offer powerful QSAR models, the book discusses and reports on integrated QSAR models, combined into a unique hybrid system.

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