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Elsevier

Books in Toxicology general

Providing a broad overview of toxicological principles, mechanisms, and testing methods, this portfolio supports researchers, regulators, and clinicians. It features foundational concepts, emerging trends, and case studies that underpin safe chemical and drug use.

  • Handbook of Arsenic Toxicology

    • 2nd Edition
    • Swaran Jeet Singh Flora
    • English
    Handbook of Arsenic Toxicology, Second Edition presents the latest findings on arsenic, including its chemistry, sources and effects on the environment and human health. The book discusses both acute and chronic effects, discussing many aspects of arsenic, from physical and chemical properties, exposure, epidemiology, organ toxicity, diagnosis, prevention and treatment. Fully updated and revised, this new edition includes new topics on risk assessment, molecular mechanisms of arsenic, advances in the integrated approach to testing, assessment and development, evaluation and application of high content predictive models, and new alternative methods (NAMS) in the context of Adverse Outcome Pathways (AOPs) to assess toxicology. This comprehensive resource allows readers to effectively assess the risks related to arsenic, providing them with all they need to know on arsenic exposure, toxicity and toxicity prevention.

  • Fundamentals of Nanotoxicology

    Concepts and Applications
    • 1st Edition
    • PK Gupta
    • English
    Fundamentals of Nanotoxicology: Concepts and Applications provides an outline to fundamental concepts of nanotoxicology and their applications. The book opens historical oversights on nanotechnology, terminology, comparison of nanomaterial sizes, and an overview of regulations. It then goes on to cover types, classifications, sources and properties. It also delves into mechanisms of toxicity as well as health and safety assessments. Biomedical, agricultural, and food applications are explored, and ecotoxicology and the environmental impact on nanomaterials rounds out the book’s overview of this topic. This book will be a helpful resource for understanding concepts and current knowledge to academics, advanced students, and researchers interested in entering or learning more about this interdisciplinary field of study.

  • Fungal Toxins

    A Comprehensive Treatise
    • 1st Edition
    • Alex Ciegler + 2 more
    • English
    Microbial Toxins, Volume VI: Fungal Toxins covers information on the evaluation of the chemical, biological, and biomedical aspects of the fungal toxins. The book discusses the historical structure chemistry, production, analysis, detoxification, biosynthesis, pharmacology, toxicology, and molecular biochemistry of aflatoxins and related compounds. The text also describes the isolation, analysis, production, chemistry, biological effects, and biogenesis of the ochratoxins, as well as the bioproduction, biosynthesis, and chemical properties of misclellaneous Aspergillus toxins. Various species of storage fungi, including yellowed rice toxins, luteoskyrin and related compounds, chlorine-containing compounds, citrinin, and citreoviridin are also considered. The book further tackles the physical and chemical properties and the biological activity of the rubratoxins; the biosynthesis and biochemical effects of patulin, penicillic acid, and other carcinogenic lactones; as well as the structure, production, biosynthesis, and biological effects of cyclopiazonic acid and related toxins. The text also encompasses bioproduction, properties, chemical structure, and biological activity of miscellaneous Penicillium toxins. Microbiologists, biochemists, epidemiologists, pharmacologists, toxicologists, medical students and people involved in other related fields will find the book useful.

  • Bacterial Endotoxins

    A Comprehensive Treatise
    • 1st Edition
    • Solomon Kadis + 2 more
    • English
    Microbial Toxins, Volume V: Bacterial Endotoxins covers the physiology, pathology, and immunology of bacterial endotoxins. The book discusses the relationship of lipopolysaccharide structure to bacterial virulence; the importance of blood-group and Forssman antigenic determinants in interactions between human and microbes; and the chemical modification of endotoxin and inactivation of its biological properties. The text also describes the effects of endotoxic lipopolysaccharides on the complement system; the host-dependent detoxification of bacterial endotoxin; and the metabolic effects of bacterial endotoxins. The release of vasoactive agents and the vascular effects of endotoxin are also considered. The book further tackles the febrile response to endotoxin; some major aspects and the relationship between shock and endotoxemia; as well as the effects of lipopolysaccharides (endotoxins) on the susceptibility to infections. The text also encompasses the role of hypersensitivity and tolerance in reactions to endotoxins. Pathologists, immunologists, physiologists, and microbiologists will find the book invaluable.

  • Man and Biologically Active Substances

    The Effect of Drugs, Diet and Pollution on Health
    • 1st Edition
    • I. I. Brekhman
    • English
    Man and Biologically Active Substances: The Effect of Drugs, Diet and Pollution on Health presents an introduction to the pharmacology of health. This book describes the medicinal substances taken by a healthy individual for specific purposes in health maintenance. Organized into four chapters, this book begins with an overview of the doctrine of health and the doctrine of the nature and treatment of illness. This text then examines the important tasks of pharmacosanation in the utilization of biologically active substances that are useful to human activity and the elimination of those that are harmful. Other chapters consider some of the more significant products used by everyone or those special pharmacosanation substances that have been widely utilized as useful food products. This book discusses as well the usefulness of several kinds of plant materials used as medicines. The final chapter deals with the science of remedies for treating human illnesses. This book is a valuable resource for nutritionists and pharmacologists.

  • Cellular and Molecular Toxicology

    Volume 14
    • 1st Edition
    • J.P. Vanden Heuvel + 3 more
    • English
    Volume 14 in the series Comprehensive Toxicology extends and complements the previously published 13-volume set. This volume will be available separately.Toxicolog... is the study of the nature and actions of chemicals on biological systems. In more primitive times, it really was the study of poisons. However, in the early 1500s, it was apparent to Paracelsus that "the dose differentiates a poison and a remedy". Clearly, the two most important tenets of toxicology were established during that time. The level of exposure (dose) and the duration of exposure (time) will determine the degree and nature of a toxicological response.Since that time the discipline of toxicology has made major advances in identifying and characterizing toxicants. The growth of toxicology as a scientific discipline has been driven to a large extent by the use of extremely powerful molecular and cell biology techniques. The overall aim of this volume is to demonstrate how these advances are being used to elucidate causal pathways (or linkages) for potential adverse health consequences of human exposure to environmental chemicals or radiation.A unique feature of this volume is its illustration of how carefully-designed studies of the molecular mechanisms of chemical action provide not only understanding of the potential toxicity of the chemical under investigation, but also new insights into the functioning of the biological system used as an experimental model. Each chapter contains a listing of major peer-reviewed articles and reviews and useful web-sites. In addition, each chapter contains a broad introductory section that outlines the subsequent sections. These Introductory and Overview sections are designed to be stand alone chapters, and may be packaged as a textbook in graduate level courses.

  • Encyclopedia of Toxicology, Volume 3

    • 1st Edition
    • Bozzano G Luisa
    • English

  • Fundamentals of Toxicologic Pathology

    • 1st Edition
    • Colin G. Rousseaux + 1 more
    • English
    Fundamentals of Toxicologic Pathology focuses on providing basic information integrated from both toxicology and pathology dealing with the mechanisms of toxic injury and morphologic expression of that injury at the subcellular, cellular, and tissue levels. This text is an enhanced and edited version of the Handbook of Toxicologic Pathology, creating a more concise and affordable text ideal for graduate students of toxicologic pathology and scientists working in academia or industry.

  • Female Reproductive Toxicology

    • 1st Edition
    • Jerrold J. Heindel + 1 more
    • English

  • Tissue-Specific Toxicity

    Biochemical Mechanisms
    • 1st Edition
    • Wolfgang Dekant + 1 more
    • English
    This volume provides an up-to-date review of the molecular mechanisms of toxicity. Individual chapters deal with specific aspects of toxicity problems associated with selected organs.

  • Essays in Toxicology

    Volume 3
    • 1st Edition
    • Wayland J. Hayes
    • English

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