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Elsevier

Books in Physical sciences and engineering

  • Small Molecule Drug Discovery

    Methods, Molecules and Applications
    • 1st Edition
    • Andrea Trabocchi + 1 more
    • English
    Small Molecule Drug Discovery: Methods, Molecules and Applications presents the methods used to identify bioactive small molecules, synthetic strategies and techniques to produce novel chemical entities and small molecule libraries, chemoinformatics to characterize and enumerate chemical libraries, and screening methods, including biophysical techniques, virtual screening and phenotypic screening. The second part of the book gives an overview of privileged cyclic small molecules and major classes of natural product-derived small molecules, including carbohydrate-derived compounds, peptides and peptidomimetics, and alkaloid-inspired compounds. The last section comprises an exciting collection of selected case studies on drug discovery enabled by small molecules in the fields of cancer research, CNS diseases and infectious diseases. The discovery of novel molecular entities capable of specific interactions represents a significant challenge in early drug discovery. Small molecules are low molecular weight organic compounds that include natural products and metabolites, as well as drugs and other xenobiotics. When the biological target is well defined and understood, the rational design of small molecule ligands is possible. Alternatively, small molecule libraries are being used for unbiased assays for complex diseases where a target is unknown or multiple factors contribute to a disease pathology.

  • Biocompatibility and Performance of Medical Devices

    • 2nd Edition
    • Jean-Pierre Boutrand
    • English
    Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies.

  • Antibiotics and Antimicrobial Resistance Genes in the Environment

    Volume 1 in the Advances in Environmental Pollution Research series
    • 1st Edition
    • Muhammad Zaffar Hashmi
    • English
    Antibiotics and Antimicrobial Resistance Genes (AMR) in the Environment summarizes and updates information on antibiotic producing organisms and their resistance and entry routes in soil, air, water and sediment. As antibiotic use continues to rise in healthcare, their fate, bioavailability and biomonitoring, and impacts on environment and public health are becoming increasingly important. The book addresses the impact of antibiotics and AMR to environment and public health and risk assessment. Moreover, it focused on the metagenomics and molecular techniques for the detection of antibiotics and antimicrobial genes. Lastly, it introduces management strategies, such as treatment technologies for managing antibiotics and AMR/ARGs-impacted environment, and bioremediation approaches.

  • Powdered Crude Drug Microscopy of Leaves and Barks

    • 1st Edition
    • Vidhu Aeri + 2 more
    • English
    Powdered Crude Drug Microscopy of Leaves and Barks investigates various microscopic techniques used in the examination of structural and cellular features in order to determine their botanical origin. These methods are useful in identifying species with similar morphological characters. Today, there is a variety of methods available to authenticate herbal drugs, ranging from simple morphological examination to physical and chemical analysis, and DNA molecular biology. Due to cost, powder microscopy is the most practical method for primary authentication. Botanical microscopy is a unique, valuable, rapid and cost-effective assessment tool, and plays an important role in the authentication and assessment of medicinal plants. This book is an essential resource for students and researchers involved in the study of plants and natural products, as well as professionals in industries manufacturing plant-based products for use during quality control and assurance steps.

  • Lignocellulosic Biomass to Liquid Biofuels

    • 1st Edition
    • Abu Yousuf + 2 more
    • English
    Lignocellulosic Biomass to Liquid Biofuels explores the existing technologies and most recent developments for the production of second generation liquid biofuels, providing an introduction to lignocellulosic biomass and the processes for its conversion into biofuels. The book demonstrates biorefinery concepts compared with petro refinery, as well as the challenges of second generation biofuels processing. In addition to current pre-treatment techniques and their technical, environmental and economic implications, chapters included also further examine the particularities of conversion processes for bioethanol, biobutanol and biodiesel through chemical, biochemical and combined approaches. Finally, the book looks into concepts and tools for techno-economic and environmental analysis, which include supply chain assessment, by-products, zero-waste techniques and process evaluation and optimization. Lignocellulosic Biomass to Liquid Biofuels is particularly useful for researchers in the field of liquid biofuels seeking alternative chemical and biochemical pathways or those interested advanced methods to calculate maximum yield for each process and methods to simulate the implications and costs of scaling up. Furthermore, with the introduction provided by this volume, researchers and graduate students entering the field will be able to quickly get up to speed and identify knowledge gaps in existing and upcoming technology the book’s comprehensive overview.

  • Decision Making in Emergency Management

    • 1st Edition
    • Jan Glarum + 1 more
    • English
    Decision-Making in Emergency Management examines decisions the authors have made over their careers based on their combined training, experience and instinct. Through a broad range of case studies, readers discover how experience impacts decision-making in conjunction with research and tools available. While the use of science, data and industry standards are always the best option when it comes to handling emergency situations, not all emergency situations fit one known solution. This book comprehensively explores the question "Is ‘instinct’ a viable factor when faced with a challenging situation and how close does it match up with the best science available?"

  • Engineered Nanomaterials and Phytonanotechnology: Challenges for Plant Sustainability

    • 1st Edition
    • Volume 87
    • English
    Engineered Nanomaterials and Phytonanotechnology: Challenges for Plant Sustainability, Volume 87 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on the Environmental application of nanomaterials: A promise to sustainable future, Plant-nanoparticle interactions: Mechanisms, effects, and approaches, A general overview on application of nanoparticles in agriculture and plant science, Engineered nanomaterials uptake, bioaccumulation and toxicity mechanisms in plants, Engineered nanomaterials in plants: Sensors, carriers, and bio-imaging, Antioxidant role of nanoparticles for enhancing ecological performance of plant system, Toxicity assessment of metal oxide nanoparticles on terrestrial plants, and much more.

  • Handbook of Magnetic Materials

    • 1st Edition
    • Volume 28
    • Ekkes H. Brück
    • English
    Handbook of Magnetic Materials, Volume 28, covers the expansion of magnetism over the past few decades and its applications in research, notably the magnetism of several classes of novel materials that share the presence of magnetic moments with truly ferromagnetic materials. The book is an ideal reference for scientists active in magnetism research, providing readers with novel trends and achievements in magnetism. Each article contains an extensive description given in graphical, as well as tabular form, with much emphasis placed on the discussion of the experimental material within the framework of physics, chemistry and materials science.

  • Advanced Nanostructures for Environmental Health

    • 1st Edition
    • Lucian Baia + 3 more
    • English
    Advanced Nanostructures for Environmental Health shows how advanced nanostructures are used to meet the most important challenges of our age. The book presents examples of how advanced nanostructures can detect and remove pollutants and other contaminant harmful to people’s health and provides examples of diagnosis tools based on advanced nanostructures. Treatment possibilities with the use of nanostructures, such as phototherapeutic applications, radiation based treatment methods, and drug delivery systems are also explored.

  • Handbook on the Physics and Chemistry of Rare Earths

    Including Actinides
    • 1st Edition
    • Volume 56
    • Jean-Claude G. Bunzli + 1 more
    • English
    Handbook on the Physics and Chemistry of Rare Earths: Including Actinides, Volume 56, is a continuous series of books covering all aspects of rare earth science, including chemistry, life sciences, materials science and physics. The book's main emphasis is on rare earth elements [Sc, Y, and the lanthanides (La through Lu], but whenever relevant, information is also included on the closely related actinide elements. Individual chapters in this release include Lanthanide Molecules for Spin-based Quantum Technologies, Modeling Intramolecular Energy Transfer in Lanthanide Chelates: A Critical Review and Recent Advances, and Superconducting Uranium-Based Materials.

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