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Elsevier

Books in Biological and medical physics

  • Physics in Biology and Medicine

    • 6th Edition
    • Paul Davidovits
    • English
    **Selected for Doody’s Core Titles® 2024 in Medical Physics**Physics in Biology and Medicine, Sixth Edition includes new, revised material, and corresponding exercises on many exciting developments in the field. New sections cover biomechanics, biotribology, frictional properties of biological materials, 3-D printing and its use in medicine, new materials in dentistry, microfluidics, bioelectronic medicine, microsensors, and microscopy. This revised edition delivers helpful and engaging additions to the role and importance of physics in biology and medicine, including new coverage on metamaterials, metabolism, and environmental science. It is ideal for courses in biophysics, medical physics, and related subjects.

  • Advances in Accelerators and Medical Physics

    • 1st Edition
    • Toshiyuki Shirai + 2 more
    • English
    Radiotherapy is now one of the major cancer treatments. The field of accelerator and medical physics is important and growing to support high precision cancer radiotherapy. Advances in Accelerators and Medical Physics provides in-depth and comprehensive coverage of the basic concepts in x-ray therapy, electron beam therapy, particle therapy, boron neutron capture therapy, and molecular imaging and therapy. Novel technologies such as FLASH therapy and laser ion accelerator are also introduced. Each section of the book presents the current state of accelerators, irradiation methods and therapy technologies, as well as future trends in advanced research. This book will serve as a key resource for researchers and students to find all information on latest cancer radiotherapy technologies and methods.

  • Advances in Nano and Biochemistry

    Environmental and Biomedical Applications
    • 1st Edition
    • Pranay Pradeep Morajkar + 1 more
    • English
    Advances in Nano and Biochemistry: Environmental and Biomedical Applications gives insights into this advanced interdisciplinary science that encompasses the principles of physics and physical chemistry for the investigation of various processes and problems in biological systems. The book is a concise culmination of biophysical chemistry knowledge acquired through core concepts and advanced technologies for addressing emerging challenges in environmental and biomedical applications. Sections cover early diagnostic techniques and accurate treatment strategies using bioinspired, sustainable technologies, including nanomaterials, nanoenzymes, biopolymers, electrochemical biomolecule sensors, biocompatible magnetic nanomaterials, quantum dots and hybrid structures, and DNA nanotechnology. Other sections discuss advanced technologies for sensing and remedying environmental pollutants, including but not limited to, photocatalytic oxidations, gum polysaccharides based nanostructured materials, bio-inspired and biocompatible nanomaterials, hydrogel nanocomposites, and contemporary enzymes and nanozymes based technologies. Ultimately, the state-of-the-art chapters in this book will empower researchers to combine two complementary elements - chemical analysis use and biomedical applications.

  • Advances in Quantum Chemistry

    • 1st Edition
    • Volume 86
    • English
    Advances in Quantum Chemistry, Volume 86 highlights new advances in the field, with this new volume presenting topics covering Can orbital basis sets compete with explicitly correlated ones for few-electron systems?, Converging high-level equation-of-motion coupled-cluster energetics with the help of Monte Carlo and selected configuration interaction, Coupled cluster downfolding techniques: a review of existing applications in classical and quantum computing for chemical systems, Multi-reference methods for the description of dynamic and nondynamic electron correlation effects in atoms and molecules, Exploring the attosecond laser-driven electron dynamics in the hydrogen molecule with different TD-CI approaches, and much more. Additional sections cover Molecular systems in spatial confinement: variation of linear and nonlinear electrical response of molecules in the bond dissociation processes, Relativistic Infinite-order two-component methods for heavy elements, Second quantized approach to exchange energy revised – beyond the S^2 approximation, Calculating atomic states without the Born-Oppenheimer approximation, Convergence of the Correlated Optimized Effective Potential Method, and more.

  • Breast MRI

    State of the Art and Future Directions
    • 1st Edition
    • Volume 5
    • Katja Pinker + 2 more
    • English
    Breast MRI: State of the Art and Future Directions provides a comprehensive overview of the current applications of breast MRI, including abbreviated MRI, as well as presenting technical recommendations, practical implementation and associated challenges in clinical routine. In addition, the book introduces novel MRI techniques, multimodality imaging, and advanced image processing coupled with AI, reviewing their potential for impeding and future clinical implementation. This book is a complete reference on state-of-the-art breast MRI methods suitable for MRI researchers, radiographers and clinicians.Breast cancer is one of the leading causes of death among women with early detection being the key to improved prognosis and survival. Magnetic resonance imaging (MRI) of the breast is undisputedly the most sensitive imaging method to detect cancer, with a higher detection rate than mammography, digital breast tomosynthesis, and ultrasound.

  • Quantum Boundaries of Life

    • 1st Edition
    • Volume 82
    • English
    Quantum Boundaries of Life, Volume 82 in the Advances in Quantum Chemistry series, presents current topics in this rapidly developing field that have emerged at the cross section of mathematics, physics, chemistry and biology. Topics covered include Quantum Considerations of Neural Memory, Functional Neural Electron Transport, Plasmon-polariton mechanism of the saltatory conduction in myelinated axons, Quantum Field Theory Formulation of Brain Dynamics: Nonequilibrium, Multi Field Theory Formulation of Brain Dynamics, Quantum Protein Folding, Classical-Quantum Interplay in Living Neural Tissue Function, Quantum Effects in Life Dynamics, Quantum transport and utilization of free energy in protein α-helices, and much more. The book’s message is simple. Mystics prefer to put consciousness in the cosmos to avoid Darwinism. If the seat of consciousness is found to evolve within all animals, then we have a Darwinian understanding not only of the origin of life and species according to natural selection but also concerning consciousness and, in particular, life being quantum Darwinian.

  • Tissue Elasticity Imaging

    Volume 2: Clinical Applications
    • 1st Edition
    • S. Kaisar Alam + 1 more
    • English
    Tissue Elasticity Imaging: Volume Two: Clinical Applications offers an extensive treatment of the fundamentals and applications of this groundbreaking diagnostic modality. Techniques and results are presented for the assessment of breast, prostate, heart, liver and thyroid tissues. For each application, details are provided on how to perform each technique, along with methods of interpretation, diagnostic criteria, quality assurance, challenges and case studies. This book is an essential resource for all researchers and practitioners (including scientists, radiologists, urologists, fellows and residents) interested in any elasticity imaging modality. As many diseases, including cancers, alter tissue mechanical properties, it is not always possible for conventional methods to detect changes, but with elasticity images that are produced by slow tissue deformation or low-frequency vibration, these changes can be displayed.

  • The World of Nano-Biomechanics

    • 2nd Edition
    • Atsushi Ikai
    • English
    The World of Nano-Biomechanics, Second Edition, focuses on the remarkable progress in the application of force spectroscopy to molecular and cellular biology that has occurred since the book's first edition in 2008. The initial excitement of seeing and touching a single molecule of protein/DNA is now culminating in the development of various ways to manipulate molecules and cells almost at our fingertips, enabling live cell operations. Topics include the development of molecular biosensors, mechanical diagnosis, cellular-level wound healing, and a look into the advances that have been made in our understanding of the significance of mechanical rigidity/flexibility of protein/DNA structure for the manifestation of biological activities. The book begins with a summary of the results of basic mechanics to help readers who are unfamiliar with engineering mechanics. Then, representative results obtained on biological macromolecules and structures, such as proteins, DNA, RNA, polysaccharides, lipid membranes, subcellular organelles, and live cells are discussed. New to this second edition are recent developments in three important applications, i.e., advanced AFM-data analysis, high-resolution mechanical biosensing, and the use of cell mechanics for medical diagnosis.

  • Bioprocess Engineering

    Kinetics, Sustainability, and Reactor Design
    • 2nd Edition
    • Shijie Liu
    • English
    Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems.

  • Principles of X-Ray Diagnosis

    • 1st Edition
    • David H. Trapnell
    • English
    Principles of X-Ray Diagnosis covers the system of observation and deductions of a radiologist taken from radiographs. This book is composed of 12 chapters that discuss the principles of diagnostic radiology and the methods of producing radiographs. Some of the topics covered in the book are the production of X-rays; formation of radiographic image; application and definition of fluorescence; intensification of an image; determining the quality of a radiograph; practical problems of radiography; preparing a radiograph; analysing defects in radiographs; and factors affecting film quality. Other chapters provide the method of determining lesion site and the detection and significance of fluid levels. These topics are followed by descriptions of the characteristics and assessment of chest radiographs. The final chapter is devoted to the normal radiographic anatomy of the heart. The book can provide useful information to the radiologists, doctors, students, and researchers.

  • Protein Physics

    A Course of Lectures
    • 2nd Edition
    • Alexei V. Finkelstein + 1 more
    • English
    Protein Physics: A Course of Lectures covers the most general problems of protein structure, folding and function. It describes key experimental facts and introduces concepts and theories, dealing with fibrous, membrane, and water-soluble globular proteins, in both their native and denatured states. The book systematically summarizes and presents the results of several decades of worldwide fundamental research on protein physics, structure, and folding, describing many physical models that help readers make estimates and predictions of physical processes that occur in proteins. New to this revised edition is the inclusion of novel information on amyloid aggregation, natively disordered proteins, protein folding in vivo, protein motors, misfolding, chameleon proteins, advances in protein engineering & design, and advances in the modeling of protein folding. Further, the book provides problems with solutions, many new and updated references, and physical and mathematical appendices. In addition, new figures (including stereo drawings, with a special appendix showing how to use them) are added, making this an ideal resource for graduate and advanced undergraduate students and researchers in academia in the fields of biophysics, physics, biochemistry, biologists, biotechnology, and chemistry.

  • Progress in Biophysics and Biophysical Chemistry

    Progress Series, Volume 9
    • 1st Edition
    • J. A. V. Butler + 1 more
    • English
    Progress in Biophysics and Biophysical Chemistry, Volume 9 reviews developments in biophysics and biophysical chemistry and covers topics such as the kinetics of reactions between hemoglobin and gases; the hydrodynamics of the arterial circulation; visual pigments in humans and animals and their relation to seeing; and gradient centrifugation of cell particles. The conversion of mechanical energy into electrical energy in certain mechanoreceptors is also discussed. This book is comprised of seven chapters and begins with an overview of the general properties of hemoglobin and its reactions with gases, and how such reactions are affected by temperature. The intermediate compound theory and the combination of sheep hemoglobin with carbon monoxide are also considered. The following chapters explore the diffusion and simultaneous chemical reaction velocity in hemoglobin solutions and red cell suspensions; the hydrodynamic aspects of the arterial circulation; determination of molecular dimensions from light scattering data; and the relation of receptor potentials to the activity of complex mechanoreceptor organs containing hair cells. The final chapter is devoted to the theory and applications of the gradient centrifugation of cell particles. This volume will be of interest to both biophysicists and biochemists.

  • Applications of Nanoscience in Photomedicine

    • 1st Edition
    • Michael R. Hamblin + 1 more
    • English
    Nanoscience has become one of the key growth areas in recent years. It can be integrated into imaging and therapy to increase the potential for novel applications in the field of photomedicine. In the past commercial applications of nanoscience have been limited to materials science research only, however, in recent years nanoparticles are rapidly being incorporated into industrial and consumer products. This is mainly due to the expansion of biomedical related research and the burgeoning field of nanomedicine. Applications of Nanoscience in Photomedicine covers a wide range of nanomaterials including nanoparticles used for drug delivery and other emerging fields such as optofluidics, imaging and SERS diagnostics. Introductory chapters are followed by a section largely concerned with imaging, and finally a section on nanoscience-enabled therapeutics.

  • Comprehensive Biomedical Physics

    • 1st Edition
    • Anders Brahme
    • English
    Comprehensive Biomedical Physics, Ten Volume Set is a new reference work that provides the first point of entry to the literature for all scientists interested in biomedical physics. It is of particularly use for graduate and postgraduate students in the areas of medical biophysics. This Work is indispensable to all serious readers in this interdisciplinary area where physics is applied in medicine and biology. Written by leading scientists who have evaluated and summarized the most important methods, principles, technologies and data within the field, Comprehensive Biomedical Physics is a vital addition to the reference libraries of those working within the areas of medical imaging, radiation sources, detectors, biology, safety and therapy, physiology, and pharmacology as well as in the treatment of different clinical conditions and bioinformatics. This Work will be valuable to students working in all aspect of medical biophysics, including medical imaging and biomedical radiation science and therapy, physiology, pharmacology and treatment of clinical conditions and bioinformatics.

  • Physical Work and Effort

    Proceedings of the First International Symposium Held at the Wenner-Gren Center, Stockholm, December 2-4, 1975
    • 1st Edition
    • Gunnar Borg
    • English
    Physical Work and Effort is a collection of papers presented at the Proceedings of the First International Symposium held at Stockholm on December 2-4, 1975. This book deals with the investigations done on the clinical physiology of work and effort. This text discusses interdisciplinary measures conducted by psychologists and physiologists on both theoretical and clinical issues. Part 1 discusses basic theories; methods and results that can be found in studies relating to fatigue; visual perception; and stress that includes a simple method of rating these estimates of perceptions. Part 2 evaluates differential and developmental problems such as sex, heart rates, and the differences found in aerobic function related to childhood daily physical activities. Part 3 covers topics on clinical and applied studies such as ECG changes in asymptomatic men; perceived pain during tread-mill exercise; and changes in heart rate during work exertion or when driving under traffic conditions. Part 4 evaluates the psychophysiological intercorrelations from a series of experiments and concludes that two factors are present in the perception of exertion during physical work—the local factor and a central factor. The book also includes the use of a model to evaluate the perceived ratings of these two factors. Psychologists, physiologists, physical therapists, physiotherapists, and scientists involved in work improvement will find this book very valuable.

  • Schering Workshop on Pharmacokinetics, Berlin, May 8 and 9, 1969

    Advances in the Biosciences
    • 1st Edition
    • Gerhard Raspé
    • English
    Advances in the Biosciences 5: Schering Workshop on Pharmacokinetics, Berlin, May 8 and 9, 1969 is a collection of papers presented at the Schering Workshop on Pharmacokinetics held in Berlin, Germany, on May 8 and 9, 1969. Contributors focus on advances in the field of pharmacokinetics, including the use of digital computers in defining pharmacokinetic parameters and of mathematical models in the study of steroid dynamics. The pharmacokinetics of acetazolamide and endogenous substances is also described. This book is comprised of 19 chapters and begins with an overview of the basic concepts and experimental methods of pharmacokinetics, followed by a discussion on the general physico-chemical aspects of drug distribution. Subsequent chapters explore multiple dose elimination kinetics and drug accumulation in patients with normal and impaired kidney function; the application of analog and digital computers in pharmacokinetics; use of mathematical tools in defining pharmacokinetic parameters; and measurement of enteric absorption rate using a double tracer technique. Mathematical and statistical problems in pharmacokinetics are also presented. This monograph will be a useful resource for pharmacologists and biologists.

  • Principles of Bone X-Ray Diagnosis

    • 2nd Edition
    • George Simon
    • English
    Principles of Bone X-Ray Diagnosis follows the method set by Principles of Chest X-ray Diagnosis (Simon, 1956) in placing more value in the grouping of x-ray material according to the type of x-ray shadow rather than the clinical disease label. Biochemical and hematological values quoted throughout the book, especially in the captions to figures, are all from the Department of Pathology, St. Bartholomew's Hospital. This book is organized into 12 chapters. Much of the original text has been used in this third edition, though some changes of order have been made to give a more logical approach to the description of the bone changes seen in various diseases. A chapter on widespread and regional reduction in bone density has been completely rewritten. This volume provides radiographs to illustrate every condition described. These radiographs were selected to illustrate the principles of bone x-ray diagnosis rather than to make a complete catalogue of all the conditions referred. This book will be of interest to persons dealing with studies on the diagnostic value of bone x-ray.

  • Massage and Remedial Exercises

    In Medical and Surgical Conditions
    • 1st Edition
    • Noël M. Tidy
    • English
    Massage and Remedial Exercises: In Medical and Surgical Conditions describes the principles of certain forms of massage and remedial exercises for specific medical and surgical condition. This book is composed of 23 chapters. Considerable chapters are devoted to treatment of fractures, along with suggestions of approximate dates on which to begin the movements. Other chapters cover the treatment options for central nervous system, motor and sensory neurons, and muscle diseases. Different forms of deformities and constitutional, heart, blood, respiratory organ, abdominal, and pelvic diseases are considered in the last chapters. This book is directed primarily toward medical gymnasts.

  • Medical Imaging Technology

    • 1st Edition
    • Victor I. Mikla + 1 more
    • English
    Medical Imaging Technology reveals the physical and materials principles of medical imaging and image processing, from how images are obtained to how they are used. It covers all aspects of image formation in modern imaging modalities and addresses the techniques, instrumentation, and advanced materials used in this rapidly changing field. Covering conventional and modern medical imaging techniques, this book encompasses radiography, fluoroscopy, computed tomography, magnetic resonance imaging, ultrasound, and Raman spectroscopy in medicine. In addition to the physical principles of imaging techniques, the book also familiarizes you with the equipment and procedures used in diagnostic imaging.

  • Physics in Biology and Medicine

    • 4th Edition
    • Paul Davidovits
    • English
    Physics in Biology and Medicine, Fourth Edition, covers topics in physics as they apply to the life sciences, specifically medicine, physiology, nursing and other applied health fields. This is a concise introductory paperback that provides practical techniques for applying knowledge of physics to the study of living systems and presents material in a straightforward manner requiring very little background in physics or biology. Applicable courses are Biophysics and Applied Physics. This new edition discusses biological systems that can be analyzed quantitatively, and how advances in the life sciences have been aided by the knowledge of physical or engineering analysis techniques. The volume is organized into 18 chapters encompassing thermodynamics, electricity, optics, sound, solid mechanics, fluid mechanics, and atomic and nuclear physics. Each chapter provides a brief review of the background physics before focusing on the applications of physics to biology and medicine. Topics range from the role of diffusion in the functioning of cells to the effect of surface tension on the growth of plants in soil and the conduction of impulses along the nervous system. Each section contains problems that explore and expand some of the concepts. The text includes many figures, examples and illustrative problems and appendices which provide convenient access to the most important concepts of mechanics, electricity, and optics in the body. Physics in Biology and Medicine will be a valuable resource for students and professors of physics, biology, and medicine, as well as for applied health workers.

  • Photosynthetic Reaction Center

    • 1st Edition
    • Johann Deisenhofer + 1 more
    • English
    The availability of the photosynthetic reaction center's structure at an atomic resolution of less than three angstroms has revolutionized research. This protein is the first integral membrane protein whose structure has been determined with such precision. Each volume of the Photosynthetic Reaction Center contains original research, methods, and reviews. Together, these volumes cover our current understanding of how photosynthesis converts light energy into stored chemical energy.Volume I describes the chemistry and biochemistry of photosynthesis, including green plant photosynthesis; it is devoted to the overall features and implications of the bacterial reaction center for green plant research. It features a new description of the structure of the reaction center, followed by coverage of the antenna and light functions. Volume I also details new manipulations of the reaction center including chemical and genetic modifications. It describes how the reaction center provides reducing power via electron transfer chemistry coupled to proton uptake and release; coupling of electron transport between the oxidized reaction center and the aqueous periplasm; and the general operation of membrane-bound proteins. Additionally, this volume contains five chapters detailing facets of green plant photosynthesis important for future research.

  • Planar Lipid Bilayers

    Methods and Applications
    • 1st Edition
    • W. Hanke + 1 more
    • English
    Biological Techniques is a series of volumes aimed at introducing to a wide audience the latest advances in methodology. The pitfalls and problems of new techniques are given due consideration, as are those small but vital details not always explicit in the methods sections of journal papers.In recent years, most biological laboratories have been invaded by computers and a wealth of new DNA technology and this will be reflected in many of the titles appearing in the series.The books will be of value to advanced researchers and graduate students seeking to learn and apply new techniques, and will be useful to teachers of advanced undergraduate courses involving practical or project work.Methods of constructing artificial membranes (planar lipid bilayers) from the main components of cell membranes (lipids) date from the early 1960s.Planar bilayers offer direct, quantitative experimental approaches to the study of membranes of precisely determined composition which can be manipulated by the experimenter. Pore-forming molecules, transporter molecules, ATP-dependent enzymes and other entities can be incorporated into the bilayers to simulate biological functions.Reconstitu... of such functions in this way remains a key final step in attributing a functional role to purified cell membrane proteins.This book aims to demystify these techniques and begins with a broad overview of the development of the subject before dealing with the protocols involved.Key references are provided at the end of the book together with a list of suppliers.

  • Principles of Medical Imaging

    • 1st Edition
    • K. Kirk Shung + 2 more
    • English
    Since the early 1960's, the field of medical imaging has experienced explosive growth due to the development of three new imaging modalities-radionucl... imaging, ultrasound, and magnetic resonance imaging. Along with X-ray, they are among the most important clinical diagnostic tools in medicine today. Additionally, the digital revolution has played a major role in this growth, with advances in computer and digital technology and in electronics making fast data acquisition and mass data storage possible. This text provides an introduction to the physics and instrumentation of the four most often used medical imaging techniques. Each chapter includes a discussion of recent technological developments and the biological effects of the imaging modality. End-of-chapter problem sets, lists of relevant references, and suggested further reading are presented for each technique.

  • The Dosimetry of Ionizing Radiation

    Volume III
    • 1st Edition
    • Bozzano G Luisa
    • English
    A continuation of the treatise The Dosimetry of Ionizing Radiation, Volume III builds upon the foundations of Volumes I and II and the tradition of the preceeding treatise Radiation Dosimetry. Volume III contains three comprehensive chapters on the applications of radiation dosimetry in particular research and medical settings, a chapter on unique and useful detectors, and two chapters on Monte Carlo techniques and their applications.

  • Dynamics and Mechanisms of Photoinduced Electron Transfer and Related Phenomena

    • 1st Edition
    • N. Mataga + 2 more
    • English
    This book contains papers which examine fundamental aspects of photoinduced electron transfer reactions, an area in which a number of breakthroughs have recently occurred. The book is divided into four parts.Parts I and II are mainly concerned with the fundamental aspects of the inter- and intra-molecular charge transfer, electron transfer and related phenomena such as solvent effects, solvation dynamics, energy gap dependences and radical pair dynamics. Part III is concerned with electron transfer and energy transfer phenomena in polymers, films, crystals, and other confined systems. In Part IV, the mechanisms of the energy and electron transfer in biological photosynthetic systems, proteins and reaction center systems are discussed.

  • Carbon Isotope Techniques

    • 1st Edition
    • David C. Coleman
    • English
    Carbon Isotope Techniques deals with the use of carbon isotopes in studies of plant, soil, and aquatic biology. Topics covered include photosynthesis/trans... studies in terrestrial ecosystems; carbon relationships of plant-microbial symbioses; microbe/plant/soil interactions; and environmental and aquatic toxicology. Stable carbon isotope ratios of natural materials are also considered. Comprised of 15 chapters, this book begins with an introduction to radiation-counting instruments used in measuring the radioactivity in soil and plant samples containing carbon-14. The discussion then turns to the basic methods of 14C use in plant science, highlighted by three examples of applications in the field of plant physiology and ecology. Subsequent chapters explore the use of carbon isotope techniques for analyzing the carbon relationships of plant-microbial symbioses; the interactions of microbes, plants, and soils; and the degradation of herbicides and organic xenobiotics. Carbon dating and bomb carbon are also described. The final section is devoted to the uses and procedures for 13C and 11C. This monograph is intended for advanced undergraduate or graduate students, as well as generalist scientists who have not previously used radioisotopes or stable isotopes in their research.

  • Experimental Food Science

    • 3rd Edition
    • English
    This textbook presents the scientific basis for understanding the nature of food and the principles of experimental methodology as applied to food. It reviews recent research findings and specific technological advances related to food. Taking an experimental approach, exercises are included at the end of each chapter to provide the needed experience in planning experiments. Emphasizing the relationships between chemical and physical properties, basic formulas and procedures are included in the appendix.

  • Comprehensive Biophysics

    • 1st Edition
    • Edward Egelman
    • English
    Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics, Nine Volume Set will help bridge that communication gap. Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics, Nine Volume Set provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge.

  • Structural Biology Using Electrons and X-rays

    An Introduction for Biologists
    • 1st Edition
    • Michael F Moody
    • English
    Structural Biology Using Electrons and X-Rays discusses the diffraction and image-based methods used for the determination of complex biological macromolecules. The book focuses on the Fourier transform theory, which is a mathematical function that is computed to transform signals between time and frequency domain. Composed of five parts, the book examines the development of nuclear magnetic resonance (NMR), which allows the calculation of the images of a certain protein. Parts 1 to 4 provide the basic information and the applications of Fourier transforms, as well as the different methods used for image processing using X-ray crystallography and the analysis of electron micrographs. Part 5 focuses entirely on the mathematical aspect of Fourier transforms. In addition, the book examines detailed structural analyses of a specimen’s symmetry (i.e., crystals, helices, polyhedral viruses and asymmetrical particles). This book is intended for the biologist or biochemist who is interested in different methods and techniques for calculating the images of proteins using nuclear magnetic resonance (NMR). It is also suitable for readers without a background in physical chemistry or mathematics.

  • Bioimpedance and Bioelectricity Basics

    • 2nd Edition
    • Orjan G. Martinsen + 1 more
    • English
    Bioelectricity (or bioelectromagnetism) relates to the study of biological electrical currents, and bioimpedance deals with the measurement of electrical conductivity. They are intimately linked to biomedical engineering, with major significance for development of novel medical devices, as well as the study of biological rhythms. This completely updated new edition remains the most comprehensive reference tool for this intricate, interdisciplinary field.The authors, both internationally recognized experts in the field, have thoroughly revised the entire text. It remains the only such work that discusses in detail dielectric and electrochemical aspects, as well as electrical engineering concepts of network theory. The highly effective, easy to follow organization has been retained, with new discussion of state-of-the-art advances in finite element analysis, endogenic sources, control theory, tissue electrical properties, and invasive measurements. There are two all new chapters on bioelectricity, along with an introduction to Geselowitz theory, the Maxwell basis of bioimpedance, and multivariate analysis as an alternative.

  • The World of Nano-Biomechanics

    Mechanical Imaging and Measurement by Atomic Force Microscopy
    • 1st Edition
    • Atsushi Ikai
    • English
    By using nanotechnological methods, we can now poke around protein molecules, genes, membranes, cells and more. Observation of such entities through optical and electron microscopes tempt us to touch and manipulate them. It is now possible to do so, and scientists around the world have started pulling, pushing and cutting small structures at the base of life processes to understand the effect of our hand work.The book describes the physical properties of such life supporting structures from the molecular level with a special emphasis on their designs based on the mechanical strength and flexibility, membrane and other biological nanostructures.

  • Physics of Life

    The Physicist's Road to Biology
    • 1st Edition
    • Clas Blomberg
    • English
    The purpose of the book is to give a survey of the physics that is relevant for biological applications, and also to discuss what kind of biology needs physics. The book gives a broad account of basic physics, relevant for the applications and various applications from properties of proteins to processes in the cell to wider themes such as the brain, the origin of life and evolution. It also considers general questions of common interest such as reductionism, determinism and randomness, where the physics view often is misunderstood. The subtle balance between order and disorder is a repeated theme appearing in many contexts. There are descriptive parts which shall be sufficient for the comprehension of general ideas, and more detailed, formalistic parts for those who want to go deeper, and see the ideas expressed in terms of mathematical formulas.

  • Microdosimetric Response of Physical and Biological Systems to Low- and High-LET Radiations

    Theory and Applications to Dosimetry
    • 1st Edition
    • Yigal Horowitz
    • English
    One of the aims of this book was to focus the attention of specialists to the diversity of the effects of the ionising radiation on biological and physical systems. Special emphasis has been placed on the exquisite complexities/differe... introduced by high ionisation density versus low ionisation density irradiation in both biological and physical systems (Scholz – Chapter 1, Horowitz – Chapter 2, Olko – Chapter 3). As well we wanted to point out the need for novel experimental and theoretical approaches required to advance the important fields of micro and nanodosimetry. Important first steps have already been taken, for example, the accelerated application of semiconductor detectors in their various forms to microdosimetry and as well to practical, important applications in the radiation dosimetry of oncological procedures (Rosenfeld – Chapter 6). The vast number of applications of TLD to radiation dosimetry are not neglected; a special chapter is devoted to the application of TLDs to medical dosimetry applications (Mobit and Kron – Chapter 7) as well as a tutorial approach in an additional chapter to the cavity theories required to extrapolate dose from the detector medium to the tissue medium (Mobit and Sandison - Chapter 5). One of the major features of this book is the intensive, in depth, coverage of the theory and modelling of TL both from the solid state physics point of view (Chen – Chapter 4) and the microdosimetic point of view (Horowitz – Chapter 2 and Olko – Chapter 3). The many puzzling, quaint, quizzical features of TL science can now be understood in the framework of these advanced theoretical models, explained in straightforward, understandable terms.

  • Magnetobiology

    Underlying Physical Problems
    • 1st Edition
    • Vladimir N. Binhi
    • English
    People are immersed in electromagnetic fields from such sources as power lines, domestic appliances, mobile phones, and even electrical storms. All living beings sense electric fields, but the physical origins of the phenomenon are still unclear. Magnetobiology considers the effects of electromagnetic fields on living organisms. It provides a comprehensive review of relevant experimental data and theoretical concepts, and discusses all major modern hypotheses on the physical nature of magnetobiological effects. It also highlights some problems that have yet to be solved and points out new avenues for research. Why do some people feel unwell during a lightning storm? Why is there a correlation between the level of electromagnetic background and the incidence of cancer? Why do so many medical centers use electromagnetic exposures to treat a wide variety of disorders in humans? The international scientific community is extremely interested in a theory of magnetobiology and the answers to these and other questions, as evidenced by the growing number of research associations in the United States, Europe, and other parts of the world. The World Health Organization (WHO) has named electromagnetic contamination in occupational and residential areas as a stress factor for human beings. This book stands out among recent texts on magnetobiology because it draws on a strong foundation of empirical and theoretical evidence to explain the various effects of magnetic fields on the human body. It contains the first comprehensive collection of experimental data bearing physical information, frequency and amplitude/power spectra, and original research data on how electromagnetic fields interfere with ions and molecules inside the proteins of living organisms.

  • Biology in Physics

    Is Life Matter?
    • 1st Edition
    • Volume 2
    • Konstantin Yu. Bogdanov
    • English
    Biology in Physics is a radical new book which bridges the gap between biology and physics. The aim is to promote an interdisciplinary exchange of scientific information and ideas, in order to stimulate cooperation in research. The scope of this volume explores both the concepts and techniques of biophysics and illustrates the latest advances in our understanding of many of the specific mechanisms that are used by living organisms. This volume represents a special effort to bring together the information that would allow a nonbiologically oriented physicist to appreciate the important role that physics plays in life sciences.

  • Quantitative Functional Brain Imaging with Positron Emission Tomography

    • 1st Edition
    • Richard E. Carson + 2 more
    • English
    This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain.

  • Electronic Structure of Clusters

    Direct Variational X-I Method
    • 1st Edition
    • Volume 29
    • Per-Olov Lowdin
    • English
    Advances in Quantum Chemistry publishes surveys of current developments in the rapidly developing field of quantum chemistry--a field that falls between the historically established areas of mathematics, physics, chemistry, and biology. With invited reviews written by leading international researchers, each presenting new results, this quality serial provides a single vehicle for following progress in this interdisciplinary area.

  • Lipid Polymorphism and Membrane Properties

    • 1st Edition
    • Volume 44
    • English
    The major lipid components of biological membranes can undergo many diverse and fascinating morphological rearrangements. Studies of these diverse phases and the manner in which they are formed tends to alter the properties of ordinary bilayer membranes. This book examines the structural and biological roles of lipids forming non-lamellar structures.

  • Working With Proteins, Six-Volume Set

    • 1st Edition
    • Volume 1-6
    • Lee A. Fuiman + 5 more
    • English

  • Primer on Cerebrovascular Diseases

    • 1st Edition
    • Bo K. Siesjo + 4 more
    • English
    Primer on Cerebrovascular Diseases is a handy reference source for scientists, students, and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The book consists of short, specific chapters written by international experts on cerebral vasculature, and presents the information in a comprehensive and easily accessible manner. The book also contains valuable information on practical applications of basic research.

  • Transport Processes in Eukaryotic and Prokaryotic Organisms

    • 1st Edition
    • Volume 2
    • W.N. Konings + 2 more
    • English
    In recent years it has become evident that transport processes across membranes play a crucial role in many metabolic systems. The activities of these transport processes often determine the physiology of the organisms.This book presents a state of the art review on the analysis of a wide variety of transport systems from bacteria and eukaryotic cells. A selection has been made of those systems that have been studied at the molecular level with special emphasis paid to the energetic and other biophysical properties. The different classes of transport systems are presented in the following: primary transport, secondary transport, phosphotransferase systems, channels and porines and macromolecular transport. Within each class of transporters several systems are presented by the leading experts in the field, which has resulted in a very broad overview of transport processes in biological cells. In this way the differences in the mechanisms used for translocation become evident while on the other hand features common to the different transport systems are revealed.

  • Contemporary Enzyme Kinetics and Mechanism

    Selected Methods in Enzymology
    • 2nd Edition
    • English
    Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation. These approaches are equally useful in examining the action of newly discovered enzymes and therapeutic agents.Contemporary Enzyme Kinetics and Mechanism, Second Edition presents key articles from Volumes 63, 64, 87, and 249 of Methods in Enzymology. The chapters describe the most essential and widely applied strategies. A set of exercises and problems is included to facilitate mastery of these topics.The book will aid the reader to design, execute, and analyze kinetic experiments on enzymes. Its emphasis on enzyme inhibition will also make it attractive to pharmacologists and pharmaceutical chemists interested in rational drug design.Of the seventeen chapters presented in this new edition, ten did not previously appear in the first edition.

  • Carbon-13 NMR Spectroscopy of Biological Systems

    • 1st Edition
    • Nicolau Beckmann
    • English
    This book is intended to provide an in-depth understanding of 13C NMR as a tool in biological research. 13C NMR has provided unique information concerning complex biological systems, from proteins and nucleic acids to animals and humans. The subjects addressed include multidimensional heteronuclear techniques for structural studies of molecules in the liquid and solid states, the investigation of interactions in model membranes, the elucidation of metabolic pathwaysin vitro and in vivo on animals, and noninvasive metabolic studies performed on humans. The book is a unique mix of NMR methods and biological applications which makes it a convenient reference for those interested in research in this interdisciplinary area of physics, chemistry, biology, and medicine.

  • Numerical Computer Methods, Part B

    • 1st Edition
    • Volume 240
    • John N. Abelson + 1 more
    • English
    The contributions in this volume emphasize numerical analysis of experimental data and analytical biochemistry, with examples taken from biochemistry. They serve to inform biomedical researchers of the modern data analysis methods that have developed concmitantly with computer hardware.

  • Lasers and Optical Fibers in Medicine

    • 1st Edition
    • Abraham Katzir
    • English
    The increasing use of fiber optics in the field of medicine has created a need for an interdisciplinary perspective of the technology and methods for physicians as well as engineers and biophysicists. This book presents a comprehensive examination of lasers and optical fibers in an hierarchical, three-tier system. Each chapter is divided into three basic sections: the Fundamentals section provides an overview of basic concepts and background; the Principles section offers an in-depth engineering approach; and the Advances section features specific information on systems and biophysical parameters. All those interested in the fields of lasers and fiber optics will find this book fascinating and instructive reading.

  • Physics of NMR Spectroscopy in Biology and Medicine

    • 1st Edition
    • B. Maraviglia
    • English
    As a result of the recent expansion of nuclear magnetic resonance in biomedicine, a number of workshops and schools have been organized to introduce the NMR principles to a wider group of biologists, radiologists, neurologists, etc. The aim of most of these courses was to provide a common vocabulary and enough information about ``pulse sequences'', relaxation times, etc. in order to facilitate the use of the various types of NMR imaging systems. However, no courses were organized for the physicists who were responsible for the origin and evolution of the ideas in this area. This Enrico Fermi school was therefore organized. The topics discussed included the theoretical interpretation and prediction of NMR signals, the study of new imaging techniques up to the building of special r.f. coils and the study of new methods for analysing NMR data in the time domain.