
Breast MRI
State of the Art and Future Directions
- 1st Edition, Volume 5 - September 22, 2022
- Imprint: Academic Press
- Editors: Katja Pinker, Ritse Mann, Savannah Partridge
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 2 7 2 9 - 9
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 2 7 4 9 - 7
Breast MRI: State of the Art and Future Directions provides a comprehensive overview of the current applications of breast MRI, including abbreviated MRI, as well as presen… Read more

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Request a sales quoteBreast MRI: State of the Art and Future Directions provides a comprehensive overview of the current applications of breast MRI, including abbreviated MRI, as well as presenting technical recommendations, practical implementation and associated challenges in clinical routine. In addition, the book introduces novel MRI techniques, multimodality imaging, and advanced image processing coupled with AI, reviewing their potential for impeding and future clinical implementation. This book is a complete reference on state-of-the-art breast MRI methods suitable for MRI researchers, radiographers and clinicians.
Breast cancer is one of the leading causes of death among women with early detection being the key to improved prognosis and survival. Magnetic resonance imaging (MRI) of the breast is undisputedly the most sensitive imaging method to detect cancer, with a higher detection rate than mammography, digital breast tomosynthesis, and ultrasound.
Breast cancer is one of the leading causes of death among women with early detection being the key to improved prognosis and survival. Magnetic resonance imaging (MRI) of the breast is undisputedly the most sensitive imaging method to detect cancer, with a higher detection rate than mammography, digital breast tomosynthesis, and ultrasound.
- Spans the whole spectrum of breast MRI, including basic imaging techniques, indications, interpretation, and the latest cutting-edge techniques
- Reviews multiparametric MRI and abbreviated protocols, providing an outlook on the future of this technique
- Discusses the predictive and prognostic value of MRI as well as the evolving field of radiomics/genomics and AI
MRI researchers with a background in physics, computer science, biomedical engineering, mathematics, biophysics
Radiologist, clinicians
Radiologist, clinicians
- Cover image
- Title page
- Table of Contents
- Advances in Magnetic Resonance Technology and Applications Series
- Copyright
- Contributors
- Preface
- Part 1 State of the art
- Section 1 Performance and interpretation of breast MRI
- Chapter 1. Multiparametric breast MRI in clinical practice
- Introduction
- T1-weighted imaging
- Standard dynamic contrast-enhanced MRI
- T2-weighted imaging
- Diffusion-weighted imaging
- Other specific imaging sequences
- Chapter 2. Abbreviated and Ultrafast MRI
- Introduction
- Abbreviated MRI protocols
- Recent MRI screening studies
- Benefits and challenges of abbreviated MRI
- Ultrafast MRI (high temporal resolution MRI)
- Hybrid imaging—abbreviated ultrafast MRI
- Recent MRI screening studies
- Conclusions
- Chapter 3. Artifacts in breast MRI
- Introduction
- Motion artifacts
- Fat
- Susceptibility
- Other artifacts
- Conclusions
- Chapter 4. Standard terminology and reporting– Breast Imaging Reporting & Data System: magnetic resonance imaging
- Introduction
- Standard terminology
- Reporting
- Conclusions
- Chapter 5. The Kaiser score: an evidence-based clinical decision rule for dynamic contrast-enhanced breast MRI
- Introduction: why do we need the Kaiser score in breast MRI?
- Description of the Kaiser score and its criteria
- The Kaiser score
- Application of the Kaiser score in clinical practice
- Conclusions
- Chapter 6. Background parenchymal enhancement at breast MRI
- Introduction
- MRI appearance of BPE
- BPE, breast density, and FGT
- Biological basis of BPE
- Factors influencing BPE
- BPE and diagnostic performance
- Qualitative and quantitative assessments of BPE
- BPE and breast cancer risk
- BPE and treatment outcomes
- Conclusions
- Section 2 MRI characteristics of common breast lesions
- Chapter 7. MRI characteristics of benign lesions
- Introduction
- Developmental abnormalities
- Fibroadenolipomas (hamartomas)
- Lipomas
- Leiomyomas and hemangiomas
- Fibroadenomas
- Phyllodes tumor
- Cysts
- Fibrocystic changes
- Adenosis
- Infectious and inflammatory conditions
- Idiopathic granulomatous mastitis
- Pseudoangiomatous stromal hyperplasia
- Conclusions
- Chapter 8. MRI characteristics of high-risk lesions
- Introduction
- Histopathological characteristics
- Imaging findings at conventional imaging
- Imaging findings at breast MRI
- Management
- New frontiers
- Chapter 9. MRI characteristics of ductal carcinoma in situ
- Introduction
- Clinical presentations and pathologic features of DCIS
- Appearance of DCIS on dynamic contrast-enhanced MRI
- DCIS appearance on advanced MRI techniques
- MRI performance to assess the extent of DCIS
- Future directions: MRI to assess biology and prognosis
- Conclusions
- Chapter 10. MRI characteristics of invasive breast cancer
- Introduction
- Invasive ductal carcinoma
- Invasive lobular carcinoma
- Uncommon histologic subtypes of invasive breast cancer
- Special presentations of invasive breast cancer
- Conclusions
- Section 3 Clinical indications for breast MRI
- Chapter 11. Breast MRI for screening
- Introduction
- Screening in specific risk groups
- Shortcomings of screening
- Additional screening methods for women undergoing breast MRI
- General guidance
- Chapter 12. Breast MRI for staging and treatment planning
- Introduction to the role of breast MRI
- MRI for staging
- Treatment planning
- Impact of MRI on surgical outcomes
- Conclusions
- Chapter 13. Neoadjuvant therapy response assessment with breast MRI
- Introduction
- Pathologic measures of neoadjuvant therapy response
- Dynamic contrast-enhanced MRI, diffusion-weighted imaging, and MR spectroscopy: correlation with pathologic complete response
- Monitoring chemotherapy response in the axilla
- Conclusions
- Chapter 14. Breast MRI for post-treatment follow-up
- Introduction
- Posttreatment changes
- Recurrent breast cancer
- Chapter 15. Breast augmentation and postmastectomy autologous breast reconstruction on breast MRI
- Introduction
- Breast augmentation and implant-based reconstruction
- Free silicone injection
- Free-fat injection, lipofilling, lipomodeling, or autologous fat grafting
- Autologous flaps
- Latissimus dorsi flap
- TRAM (transverse rectus abdominus muscle) flap
- DIEP (deep inferior epigastric perforator) flap
- Chapter 16. Problem-solving breast MRI
- Introduction
- Evaluation of suspicious symptoms, including nipple discharge
- Equivocal imaging findings
- Conclusions
- Chapter 17. Imaging of the axilla and cancer of unknown primary
- Introduction
- Anatomy of the axilla
- Spread of metastatic disease to axillary lymph nodes
- Evaluation of axillary lymph nodes
- MR imaging of the axilla
- Detection of abnormal axillary lymph nodes on MRI
- Clinical management of metastatic axillary lymph nodes
- Radiotherapy
- Chemotherapy
- The controversial role of imaging in axillary staging
- Role of MRI in the detection and treatment of occult primary breast cancer
- Interventional techniques for axillary lymph node localization and breast MRI
- Future directions
- Conclusions
- Section 4 Breast magnetic resonance imaging—guided interventions and therapy
- Chapter 18. Biopsy, including MRI-directed US and rad-path correlation
- Introduction
- History of MRI-guided techniques
- MRI-guided biopsy
- Imaging review
- Consent process, contraindications, and risk
- Equipment
- The procedure: positioning, protocol, percutaneous biopsy
- MRI localization
- MRI-guided clip placement with subsequent mammographic/sonographic localization
- MRI-directed skin localization with subsequent excisional biopsy
- MRI-guided wire localization
- Wire-free MRI localization
- MRI-directed ultrasound
- Radiologic–pathologic correlation
- Current challenges and future directions
- Conclusions
- Chapter 19. MRI-guided minimally invasive therapy of breast lesions
- Introduction
- State of the art and methodologies
- Applications in breast care
- Conclusions
- Part 2 Future directions
- Section 5 Advanced and emerging approaches
- Chapter 20. Noncontrast MRI
- Introduction
- Diffusion-weighted MRI
- DW MRI as a supplement to conventional DCE-MRI
- DW MRI as a stand-alone modality
- Image interpretation strategies
- Technical considerations
- Emerging techniques
- Conclusions
- Chapter 21. Metabolic imaging using ultra-high field MRI
- Introduction
- Applications
- Challenges and future applications
- Conclusions
- Chapter 22. Quantitative DCE-MRI of the Breast
- Introduction
- Pharmacokinetic modeling of DCE-MRI data
- Applications of quantitative breast DCE-MRI
- Technical Considerations for Quantitative Breast DCE-MRI
- Conclusions
- Chapter 23. Diffusion MRI of the breast: standard and advanced techniques
- Introduction
- Diffusion-weighted imaging
- Advanced diffusion MRI
- Conclusions
- Chapter 24. MR spectroscopy
- Introduction
- In vivo magnetic resonance spectroscopy technique
- Data analysis
- Clinical applications
- Conclusions
- Chapter 25. Emerging techniques in breast MRI
- Introduction
- Ultrafast dynamic contrast-enhanced imaging
- Magnetic resonance elastography
- Magnetization transfer and chemical exchange saturation transfer
- Magnetic resonance spectroscopy
- Hyperpolarized [1-13C]-pyruvate
- MRI-constrained radiomics and habitat imaging
- MRI-constrained mathematical modeling
- Conclusions
- Section 6 Hybrid imaging and alternative techniques
- Chapter 26. PET/MRI hybrid imaging and targeted tracers
- Introduction
- Radiotracers
- Acquisition protocol
- New frontiers: radiomics and artificial intelligence
- Conclusions
- Chapter 27. Competing and alternative techniques to breast MRI
- Contrast-enhanced mammography
- Breast-specific gamma imaging and molecular breast imaging
- Positron emission tomography and positron emission mammography of the breast
- Future directions
- Section 7 Prognostic and predictive MR imaging biomarkers
- Chapter 28. MRI radiomics and radiogenomics for breast cancer
- Introduction
- Image preprocessing
- Feature extraction
- Prognostic and predictive radiomic biomarkers for breast cancer
- Radiogenomics
- Limitations and future directions
- Chapter 29. Breast imaging and deep learning: past, present, and future
- Introduction
- Deep learning
- Segmentation
- Detection
- Lesion classification
- Risk prediction
- Treatment response
- Molecular subtypes
- Nodal status
- Pathologic complete response
- Considerations
- Conclusions
- Index
- Edition: 1
- Volume: 5
- Published: September 22, 2022
- Imprint: Academic Press
- No. of pages: 644
- Language: English
- Paperback ISBN: 9780128227299
- eBook ISBN: 9780128227497
KP
Katja Pinker
Katja Pinker, MD, PhD, EBBI obtained her medical degree at the Medical University of Vienna in 2003. From 2005 until 2010 he was trained as a radiologist at the Department of Radiology at the Medical University of Vienna. Her focus on breast imaging began right after completing medical school in 2003 when she joined the research team of the Division of Molecular and Gender Imaging in Vienna, Austria. She benefitted from clinical research training in world-leading groups, including the Division of Molecular and Gender Imaging and the MR Centre of Excellence in the Department of Biomedical Imaging and Image-guided Therapy, the Breast Health Center at the Comprehensive Cancer Center, and the Pre-Clinical Imaging Laboratory, which endowed her with broad theoretical and practical knowledge in breast and cancer imaging, with a special focus on advanced magnetic resonance imaging (MRI). In 2008, she was awarded a European School of Radiology Visiting Scholarship at the Breast Unit, Barts and The London Cancer Centre, St. Bartholomew’s Hospital, London in 2008, and consecutively was received as a research fellow at the London Breast Institute, Princess Grace Hospital, London, UK, in 2009.
Affiliations and expertise
Associate Professor of Radiology and Faculty Member, Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, AustriaRM
Ritse Mann
Ritse Mann MD, PhD, obtained his medical degree at the University of Utrecht in the Netherlands in 2004. In 2005 he started a PhD project to the value of breast MRI in invasive lobular carcinoma at the Radboud University Medical Centre in Nijmegen, where he was trained by the late prof. dr. Carla Boetes. From 2008 to 2013 he trained as a resident in radiology, followed by a fellowship in interventional radiology at the same institution, where he now works as breast and interventional radiologist. He is, since 2010, responsible for the clinical breast research at the radiology department of the Radboudumc. The breast imaging research group of the Radboudumc is one of the largest dedicated groups in Europe with large preclinical arms in x-ray development, ultrasound and artificial intelligence. Consequently, dr. Mann’s research has a specific focus on the evaluation and implementation of novel breast imaging techniques. He also has a strong personal interest in breast MRI with a focus on the implementation of new sequences for breast screening.
Affiliations and expertise
Department of Radiology, Radboud UMC, Nijmegen, The NetherlandsSP
Savannah Partridge
Savannah C. Partridge, Ph.D. is a Professor in the Departments of Radiology and Bioengineering, and the Research Director for Breast Imaging at the University of Washington School of Medicine. She is also the Associate Director of Cancer Imaging at the Seattle Cancer Care Alliance in Seattle, Washington, USA. Dr. Partridge is a leading expert in technique optimization and clinical validation of diffusion MRI of the breast. She is an active member in multiple international cancer and imaging cooperative groups and has led two large multi-institutional breast DWI clinical trials through the Eastern Cooperative Oncology Group – American College of Radiology Imaging Network (ECOG-ACRIN).
Affiliations and expertise
Professor, Department of Radiology, University of Washington, Seattle, WA, USARead Breast MRI on ScienceDirect