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11-20 of 427 results in All results

Caspases as Molecular Targets for Cancer Therapy

  • 1st Edition
  • August 10, 2024
  • Ankur Vaidya
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 6 4 4 - 1
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 6 4 5 - 8
Caspases as Molecular Targets for Cancer Therapy discusses the recent developments on targeted therapies for cancer using caspases. It describes the selection of specific caspases for cancer therapy with the current standard of care and highlights numerous assay techniques for caspase activities. This book discusses topics such as mutations within apoptosis gene, inflammatory caspases, tumor suppression, and the different caspase types and their role in anticancer activity. In addition, it discusses caspase activity assay procedure and future perspectives. It is a valuable resource for researchers, students, and members of biomedical and medical fields who want to learn more about novel anticancer targeted therapies.

Cancer Epigenetics and Nanomedicine

  • 1st Edition
  • June 26, 2024
  • Prashant Kesharwani + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 3 2 0 9 - 4
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 3 2 1 0 - 0
Cancer Epigenetics and Nanomedicine: Targeting the Right Player via Nanotechnology is a complete package that provides a comprehensive and thorough understanding of the key players that modulate the various steps of carcinogenesis and malignant progression of the disease and the critical targets to be exploited for developing novel modalities of diagnosis and therapeutics.Since epigenetic aberrations can be potentially reversed and restored to their normal state through epigenetic therapy, the book also discusses the challenges and the future of the field with the cutting-edge revelations and limitations that this research endeavor can offer, thereby helping the readers to enhance their critical thinking and adopt strategies of therapeutic importance.

Pathophysiology and Treatment of Atherosclerotic Disease in Peripheral Arteries

  • 1st Edition
  • June 12, 2024
  • Aloke Virmani Finn
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 3 5 9 3 - 4
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 3 5 9 4 - 1
Pathophysiology and Treatment of Atherosclerotic Disease in Peripheral Arteries is a thorough review of the disease written by experts studying its detection and treatment. These state-of-the-art chapters summarize emerging knowledge about this important area of medicine. The pathophysiology and treatment of peripheral artery (PAD) disease remains poorly understood even by practitioners. Often it is assumed that PAD should be treated in a similar fashion to coronary artery disease (CAD), when in fact recent data suggest a distinct pathophysiology with genetic risk having some but not complete overlap with CAD.This is a novel reference of emerging data on the factors behind its development and progression, detection, and treatment suggest an emerging paradigm for this disease.

Medical Modeling

  • 3rd Edition
  • June 8, 2024
  • Richard Bibb + 3 more
  • English
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 5 7 3 4 - 2
Medical Modelling: The Application of Advanced Design and Rapid Prototyping Techniques in Medicine, Third Edition provides readers with a thorough update of the core contents, along with key information on innovative imaging techniques, additive manufacturing technologies, and a range of applied case studies. This comprehensive new edition includes new coverage of advanced technologies, such as selective laser melting, electron beam melting, multi jet fusion, and more. The extensive section of peer-reviewed case studies is thoroughly updated and includes additional clinical examples, describing the practical applications of advanced design technologies in surgical, prosthetic, orthotic, dental and research applications.Finally, the book explores the future potential of medical modeling, such as in simulations for training, the development of new medical devices, and more.

Application of Artificial Intelligence in Early Detection of Lung Cancer

  • 1st Edition
  • May 10, 2024
  • Madhuchanda Kar + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 5 2 4 5 - 3
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 5 2 4 6 - 0
Application of Artificial Intelligence in Early Detection of Lung Cancer presents the most up-to-date computer-aided diagnosis techniques used to effectively predict and diagnose lung cancer. The presence of pulmonary nodules on lung parenchyma is often considered an early sign of lung cancer, thus using machine and deep learning technologies to identify them is key to improve patients’ outcome and decrease the lethal rate of such disease. The book discusses topics such as basics of lung cancer imaging, pattern recognition techniques, deep learning, and nodule detection and localization. In addition, the book discusses risk prediction based on radiological analysis and 3D modeling.This is a valuable resource for cancer researchers, oncologists, graduate students, radiologists, and members of biomedical field who are interested in the potential of AI technologies in the diagnosis of lung cancer.

Bio-Inspired Strategies for Modeling and Detection in Diabetes Mellitus Treatment

  • 1st Edition
  • April 18, 2024
  • Alma Y Alanis + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 2 3 4 1 - 9
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 2 3 4 0 - 2
Bio-Inspired Strategies for Modeling and Detection in Diabetes Mellitus Treatment focuses on bioinspired techniques such as modeling to generate control algorithms for the treatment of diabetes mellitus. The book addresses the identification of diabetes mellitus using a high-order recurrent neural network trained by an extended Kalman filter. The authors also describe the use of metaheuristic algorithms for the parametric identification of compartmental models of diabetes mellitus widely used in research works such as the Sorensen model and the Dallaman model. In addition, the book addresses the modeling of time series for the prediction of risk scenarios such as hyperglycaemia and hypoglycaemia using deep neural networks. The detection of diabetes mellitus in the early stages or when current diagnostic techniques cannot detect glucose intolerance or prediabetes is proposed, carried out by means of deep neural networks present in the literature. Readers will find leading-edge research in diabetes identification based on discrete high-order neural networks trained with an extended Kalman filter; parametric identification of compartmental models used to describe diabetes mellitus; modeling of data obtained by continuous glucose-monitoring sensors for the prediction of risk scenarios such as hyperglycaemia and hypoglycaemia; and screening for glucose intolerance using glucose-tolerance test data and deep neural networks. Application of the proposed approaches is illustrated via simulation and real-time implementations for modeling, prediction, and classification.

Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy

  • 1st Edition
  • April 10, 2024
  • Vivek Asati + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 6 1 2 1 - 9
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 6 3 2 - 7
Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy discusses recently developed treatments based on molecular targets which are genetically altered in cancer cells and are essential for tumor development and survival. Considerable research effort has been devoted to the development of targeted drugs that inhibit the action of pathogenic kinases, and clinical studies performed so far have validated the positive effects of kinase inhibitors for cancer treatment. Each chapter discusses a molecular target, such as ALK2, ATR, CK, Src-Abl, EGFR, Fyn-Blk-Lyn, IGFs, and PAK1.The book's chapters are written by experts who actively work on the targets to help readers fully understand how they can be used. This is a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of novel cancer therapies based on molecular targets.

The Metaverse and Smart Cities

  • 1st Edition
  • February 28, 2024
  • Zaheer Allam + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 2 3 5 1 - 8
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 2 3 5 0 - 1
The Metaverse and Smart Cities: Urban Environments in the Age of Digital Connectivity explores the intersection between the rapidly growing metaverse and the future of cities. The metaverse is a virtual world that is increasingly gaining attention as a new frontier for human interaction and commerce. At the same time, cities are undergoing significant transformation as they face challenges such as population growth, urbanization, and environmental degradation. Urban planners and city administrators will find valuable insights on how the metaverse can be integrated into the planning and development of smart, sustainable, and future cities.The book begins with an introduction to the concepts and technology of the metaverse as well as its history. It then sheds light on the current and future challenges and opportunities that the metaverse presents to cities and the quality of life of urban dwellers. It delves into the ways in which the metaverse can change cities, both in terms of their physical and virtual environments, and the impact it can have on the lives of those who live in them. It brings together the latest research and perspectives from experts in the fields of virtual reality, urban planning, and sustainability, to provide a comprehensive and up-to-date picture of this rapidly evolving field.

Curcumin-Based Nanomedicines as Cancer Therapeutics

  • 1st Edition
  • February 21, 2024
  • Amirhossein Sahebkar + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 4 1 2 - 6
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 4 1 3 - 3
Curcumin-based Nanomedicines as Cancer Therapeutics presents a consistent and thorough overview of nanocurcumin applications in cancer treatments. It brings together the novel applications of nanocurcumin in biological milieu as well as helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries. Nanocurcumin has been widely explored for the treatment of various cancers; however, the scientific literature is inconsistent in style and structure and scattered across many sources. By providing an explicit account on vital aspects on nanocurcumin-based anticancer delivery approaches and discussing the perspectives of the technologies explored so far based upon the findings outlined, the book offers updated and in-depth knowledge on the topic in one single source written by global leading experts. In addition, the book aims to stimulate the interest of the academic researchers, industrial scientists, businessmen, and young scholars to address key multidisciplinary challenges faced by nanotechnologists to foster the desired collaboration among biologists, chemists, physicists, engineers, and clinicians to find proper and efficient new cancer treatments.

Fractional Difference, Differential Equations, and Inclusions

  • 1st Edition
  • January 11, 2024
  • Saïd Abbas + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 3 6 0 1 - 3
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 3 6 0 2 - 0
Fractional Difference, Differential Equations, and Inclusions: Analysis and Stability is devoted to the existence and stability (Ulam-Hyers-Rassias stability and asymptotic stability) of solutions for several classes of functional fractional difference equations and inclusions. Covered equations include delay effects of finite, infinite, or state-dependent nature, and tools used to establish the existence results for the proposed problems include fixed point theorems, densifiability techniques, monotone iterative technique, notions of Ulam stability, attractivity and the measure of non-compactness, as well as the measure of weak noncompactness. The tools of fractional calculus are found to be of great utility in improving the mathematical modeling of many natural phenomena and processes occurring in the areas of engineering, social, natural, and biomedical sciences. All abstract results in the book are illustrated by examples in applied mathematics, engineering, biomedical, and other applied sciences.