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Books in Organic synthesis

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Thiophenes

  • 1st Edition
  • May 12, 2004
  • Salo Gronowitz + 1 more
  • Alan R. Katritzky + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 1 9 2 2 - 7
There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows any scientist who is interested in the chemical transformations of molecules to choose between all the alternatives and assess their real advantages and limitations. With the emphasis on laboratory use, these volumes represent a comprehensive and practical guide to modern synthetic organic chemistry. This book is the product of the authors many years practical experience and reading of the original literature. It contains a valuable distillation and critical evaluation of the Best Synthetic Methods for the formation and reaction of thiophenes (five membered heterocycles containing a ring sulfur) or polymers containing a thiophene functionality (thienyls). A brief review of each area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. The reader can therefore use this book to rapidly review and select the best methods of performing a synthetic conversion to create or modify a specifically substituted thiophene. Although this book contains many references to the original literature, the large number of experimental recipes enables the user to prepare a thiophene derivative without access to the original literature. These features make the handbook especially useful for physicists working in material sciences and organic/pharmaceutical chemists, who rapidly want to find out the availability of (or how to make) a specific thiophene.

Strategies and Tactics in Organic Synthesis

  • 1st Edition
  • Volume 4
  • April 6, 2004
  • Michael Harmata
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 1 7 9 6 - 4
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, we are given stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners. First hand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought and/or good fortune give rise to successful completion of a project. In this book we learn how synthesis is really done and are educated, challenged and inspired by these stories, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

Hydrocarbon Thermal Isomerizations

  • 2nd Edition
  • March 19, 2004
  • Joseph J. Gajewski
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 7 2 9 8 - 0
Hydrocarbon Thermal Isomerizations summarizes rearrangements which are induced by heating neutral hydrocarbons under non-catalytic conditions in the vapor phase or in non-polar solution. This subject has attracted the interest of mechanistic organic chemists and theorists in the last quarter century because it is one of the few fields workable by state of the art techniques of both camps. This work collects together most of the crucial rate and stereochemical data in a single volume, along with a critical analysis of each of these reactions. Unlike reviews or other books in this area that focus on reaction types, e.g.. electrocyclic reactions, or Claisen rearrangements, this volume is organized like the Chemical Abstracts Formula Index, but with an important exception: all of the relevant derivatives of each parent compound are discussed with the parent and not in their logical formula index positions. As it is not always obvious what is a parent material and what is a derivative, detailed cross-references are included throughout. An important aspect of this edition is the inclusion of calculational results that provide insight, often more than was anticipated, into these relatively simple reactions.

Advanced Free Radical Reactions for Organic Synthesis

  • 1st Edition
  • January 14, 2004
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 2 4 2 5 - 2
Free radical reactions have become increasingly important and a very attractive tool in organic synthesis in the last two decades, due to their powerful, selective, specific, and mild reaction abilities. Advanced Free Radical Reactions for Organic Synthesis reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions. The book usefully provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications it is therefore suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students. This title is the definitive guide to radical chemistry for all scientists.

Annual Reports in Organic Synthesis-2003

  • 1st Edition
  • November 10, 2003
  • Kenneth Turnbull + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 9 9 1 7 - 8
The first three chapters of this latest volume, Annual Reports in Organic Synthesis (2003), are organised by reaction type. Later chapters deal with methods of synthesizing heterocyclic systems, the use of protecting groups and synthetically useful transformations. The final chapters deals with reviews and are divided by specific topics.

Carbohydrates

  • 1st Edition
  • April 22, 2003
  • Helen Osborn
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 2 8 5 2 - 6
There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows the practising synthetic chemist to choose between all the alternatives and assess their real advantages and limitations. Each chapter in Carbohydrates details a particular theme associated with carbohydrate synthesis. A brief review of the subject area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. In order for the roles of carbohydrates to be thoroughly analysed and assessed, glycobiologists require access to defined target carbohydrates in useful quantities. Thus carbohydrates and glycoconjugates are now recognized as important targets for total synthesis programmes and it is essential to develop efficient regio- and stereoselective methods for the synthesis of carbohydrates. Whilst carbohydrates can sometimes be isolated from natural sources, synthetic strategies often offer the advantage of allowing access to larger quantities of material as well as entry to analogues of the natural carbohydrates.

Enzymology and Molecular Biology of Carbonyl Metabolism 10

  • 1st Edition
  • May 14, 2001
  • H. Weiner
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 0 6 4 1 - 2
The largest collection of articles on the three major gene families, this work ranges from enzymology to molecular biology to physiological implications. The three gene families are related in that the enzymes catalyse the NAD(P) dependent oxidation or reduction of carbonyl containing substrates. The substrates are important in diverse areas such as alcoholism, diabetes and cancer related problems as well as simple detoxification. The scope of the chapters, contributed by leading international scientists, is wide and covers gene regulation to enzyme mechanisms and protein structure. This is the only publication dealing in such depth with just three gene families. An important reference for researchers in toxicology and molecular biology.

Perspectives in Organopalladium Chemistry for the 21st Century

  • 1st Edition
  • November 9, 1999
  • J. Tsuji
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 0 1 9 7 - 4
Perspectives in Organopalladium Chemistry for the 21st Century is a monograph on modern organopalladium chemistry, with an emphasis on the use of palladium in organic synthesis. The collection of articles is reprinted from a special issue of the Journal of Organometallic Chemistry.The field of organopalladium chemistry is evolving rapidly, building on a growing catalogue of reactions that employ palladium-containing catalysts. This book should hold particular interest for those who apply palladium reagents and catalysts to organic synthesis; in fact, palladium is considered by many to be the most useful transition element employed for organic syntheses. This selection of articles by leading scientists, published as "Perspectives in Organopalladium Chemistry for the 21st Century", provides an impressive overview of the field that every chemist who works with organometallic palladium catalysts should read.

Ligand Coupling Reactions with Heteroatomic Compounds

  • 1st Edition
  • Volume 18
  • October 7, 1998
  • Jean-Pierre Finet
  • English
  • Hardback
    9 7 8 - 0 - 0 8 - 0 4 2 7 9 4 - 2
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 1 0 1 8 - 7
The whole field of ligand coupling has only emerged in the last decade as a basis for new synthetic transformations. As Professor Finet shows in this comprehensive survey, the recent clarification of reaction mechanisms of ligand coupling process around heteroatom centres, now provides an understanding of these reactions which are certain to permit their application in organic synthesis, thereby achieving transformations which are quite difficult to achieve by other methods. This book provides in a thorough and scholarly way, a balanced coverage of the whole field.

Solid-Supported Combinatorial and Parallel Synthesis of Small-Molecular-Weight Compound Libraries

  • 1st Edition
  • Volume 17
  • September 1, 1998
  • D. Obrecht + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 0 8 - 0 4 3 2 5 8 - 8
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 1 7 3 6 - 0
The words "Combinatorial Chemistry" have different meanings to different people, ranging from split and mix strategies to parallel synthesis using robots, and embracing the whole range of preparative chemistry from organic molecules, to catalyst ligands, and even inorganic solids. All of these activities have in common an attempt to expand the diversity of structure available to the chemist as well as the access to this diversity, permitting the discovery of new and valuable biological acid material properties. In this outstanding survey of combinatorial organic chemistry, the authors, Obrecht who has established a new combinatorial chemistry company called Polyphor, and Villalgardo have brought together the literature, including that from 1998, and have concisely analysed the applications and achievements of this new field. This work will be of value to all chemists engaged in preparative work, both in industry and academe.