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Books in Medicinal chemistry

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81-90 of 110 results in All results

Chemistry and Biology of Heparin and Heparan Sulfate

  • 1st Edition
  • December 14, 2005
  • Hari G. Garg + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 0 8 - 0 4 4 8 5 9 - 6
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 2 9 0 5 - 9
The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area.

Landmark Papers in Clinical Chemistry

  • 1st Edition
  • November 15, 2005
  • Richard M. Rocco
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 1 9 5 0 - 4
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 5 8 9 4 - 6
This is the first major review of the developments in clinical laboratory science in the 20th century presented in the words of the original inventors and discoverers. Introductory comments by the editor help place the works within the historical context.Landmark Papers addresses:*The origin of the home pregnancy test available today in every drugstore*The woman who invented a billion dollar technology, refused to patent it and went on to win a Nobel Prize*The scientists who worked on the US Government’s crash program at the start of WWII to find a substitute for the malaria drug quinine*The blood test used to monitor the effectiveness of cholesterol lowering drugs that today are taken by over 20 million patients*The graduate student who invented a technology for testing for infectious diseases, took it to Africa to screen people for malaria for the first time and which is now used to test for HIV infection world-wide*The invention of molecular diagnostics by Linus Pauling and the road to individualized medicine*The development of the glucose meter used by diabetics up to six times a day to monitor their metabolic control

Progress in Medicinal Chemistry

  • 1st Edition
  • Volume 43
  • April 16, 2005
  • F.D. King + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 1 5 7 2 - 8
The Progress in Medicinal Chemistry series spans a wide range of topics of interest to the drug discovery community. This particular volume touches upon the following:* The Herg ion channel * Fluorescence-based high throughput assay * Aprepitant and neurokinin receptors * Muscarinic receptor targets * Gene activation pathways * Malaria and antimalarial drugs * HIV virus mutation and new therapeuticsProgress in Medicinal Chemistry is available online on ScienceDirect — full-text online of volumes 41 onwards. Elsevier book series on ScienceDirect gives multiple users throughout an institution simultaneous online access to an important compliment to primary research. Digital delivery ensures users reliable, 24-hour access to the latest peer-reviewed content. The Elsevier book series are compiled and written by the most highly regarded authors in their fields and are selected from across the globe using Elsevier’s extensive researcher network. For more information about the Elsevier Book Series on ScienceDirect Program, please visit:http://www.info.sciencedirect.com/bookseries/

Annual Reports in Medicinal Chemistry

  • 1st Edition
  • Volume 39
  • December 15, 2004
  • Annette M. Doherty
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 7 1 9 7 - 6
Annual Reports in Medicinal Chemistry continues to focus on providing timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design.

The Role of Chemistry in the Evolution of Molecular Medicine

  • 1st Edition
  • April 16, 2004
  • Imre Csizmadia + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 1 5 8 8 - 9
This volume entitled 'The Role of Chemistry in the Evolution of Molecular Medicine' contains a collection of papers that form the proceedings of the Symposium held at the University of Szeged (27-29 June 2003). As well as covering developments in the field over the last 60 years, the proceedings of this Symposium has laid the foundations for the future of the field of molecular medicine. Contributors span a wide range of molecular science disciplines including mathematics, physics, computer science, chemistry, biochemistry, biology and medicine, and cover the whole territory in agreement with the legacy of Professor Albert Szent-Györgyi. This volume was particularly inspired by the booklet published in 1960 by Albert Szent-Györgyi under the title 'Introduction to submolecular biology', and the contents of this booklet have been included here in its entirety as an Appendix.

The Practice of Medicinal Chemistry

  • 2nd Edition
  • June 11, 2003
  • Camille Georges Wermuth
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 9 7 7 7 - 8
The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process.

Advances in Clinical Chemistry

  • 1st Edition
  • Volume 37
  • February 19, 2003
  • Herbert E. Spiegel
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 9 0 2 6 - 7
This volume, edited for the last time by H.E. Spiegel, continues the objective of expanding the intellectual horizon of clinical chemistry. The fields of analytical, anatomical, sub-cellular and molecular sciences are all represented in this volume.

Macrolide Antibiotics

  • 2nd Edition
  • June 10, 2002
  • Satoshi Omura
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 5 2 6 4 5 1 - 8
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 3 5 6 8 - 5
Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treament.

The Proteome Revisited

  • 1st Edition
  • Volume 63
  • October 25, 2001
  • A. Stoyanov + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 0 5 2 6 - 2
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 1 8 9 6 - 1
The book deals with the theory and practice of all electrophoretic steps leading to proteome analysis, i.e. isoelectric focusing (including immobilized pH gradients), sodium dodecyl sulphate electrophoresis (SADS-PAGE) and finally two-dimensional maps. It is a reasoned collection of all modern, relevant, up-to-date methodologies leading to successful fractionation, analysis and characterization of every polypeptide spot in 2-D map analysis. It includes chapters on the most sophisticated mass spectrometry developments and it helps the reader in navigating through the most important databases in proteome analysis, including step by step tours in selected sites. Yet, this book's unique strength and feature is the fact that it combines not only practice (in common with any other book on this topic) but also theory, by giving a detailed treatment on the most advanced theoretical treatments of steady-state techniques, such as isoelectric focusing and immobilized pH gradients. A lot of this theory is newly developed and presented to the public for the first time. Thus, this book should satisfy not only the needs of every day practitioners, but also the desires of the most advanced theoreticians in the field, who will surely appreciate the novel theories presented here. Also the methodological section contains several as yet unpublished protocols, correcting some of the existing ones and showing the pitfall and limitations of even well ingrained protocols in proteome analysis, which are here critically re-evaluated for the first time.

Advances in Clinical Chemistry

  • 1st Edition
  • Volume 36
  • October 9, 2001
  • Herbert E. Spiegel + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 9 0 2 5 - 0
For more than thirty years, this serial has broadened the technical scope and expanded the scientific base of clinical chemistry. These volumes clarify the areas of molecular biology and informatics and the monitoring of physiological parameters in critical situations as they pertain to clinical chemistry. Each volume of Advances in Clinical Chemistry contains an index, and each chapter includes references.