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Books in Analytical separations

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Pharmaceutical and Biomedical Applications of Liquid Chromatography

  • 1st Edition
  • Volume 1
  • November 12, 2012
  • W.J. Lough + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 9 8 4 5 4 - 4
This volume reflects the changes that have taken place in the pharmaceutical industry over the last ten years, most notably the increased importance attached to the question of chirality, the growing influence of biotechnology and the need for more rigorous documentation and validation of analytical methods and procedures.The first part of this book deals with the application of new technology to pharmaceutical and biomedical analysis, reflecting the present needs for increased speed, sensitivity and selectivity in the analysis of drugs. The second chapter provides an overview of capillary electophoresis, which represents one of the most inportant analytical developments to impact directly on pharmaceutical development in recent years. Although not a chromatographic technique, capillary electrophoresis was considered too important to be ignored.Over the last 25 years, liquid chromatography has grown into a mature analytical technique and many of the fundamental issues concerned with retention and separation are well defined. The practitioners of modern liquid chromatography spend as much time in the development of techniques for sampling handling and automation as they do in the development of the separation. Therefore, Part Two of this book describes some of the recent advances in the areas of sample handling and the isolation of compounds from biological samples, including solid phase extraction, restricted access media for direct injection, coupled column technology and microdialysis. Similarily, Part Three contains two chapters concerned with liquid chromatographic methods for the isolation of drug substances, peptides and proteins from other complex media.The pharmaceutical industry and the process of drug development are highly regulated and the increasing importance that the regulatory authorities attach to validation has had a significant impact on the analytical techniques used for the analysis of drugs. Although this has increased the workload of analysts in the pharmaceutical industry, it has also improved the quality of analytical methods used in the support of investigational and new drug applications as well as the quality of methods published more recently in the literature. Consequently, Part Four of this volume describes approaches to the optimization and validation of liquid chromatography methods for the analysis of drugs in the bulk form, in pharmaceutical formulations and biological fluids.

Essentials in Modern HPLC Separations

  • 1st Edition
  • September 21, 2012
  • Serban C. Moldoveanu + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 8 5 0 1 3 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 3 8 5 0 1 4 - 0
Essentials in Modern HPLC Separations discusses the role of separation in high performance liquid chromatography (HPLC). This up-to-date reference systematically covers new developments in types and characteristics of stationary phases, mobile phases, and other factors of this technique that influence separation of compounds being analyzed. The volume also considers the selection process for stationary and mobile phases in relation to the molecules being separated and examined, as well as their matrices. The book includes a section on the contemporary applications of HPLC, particularly the analysis of pharmaceutical and biological samples, food and beverages, environmental samples, and more.

Gas Chromatography

  • 1st Edition
  • June 19, 2012
  • Colin Poole
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 8 5 5 4 0 - 4
  • eBook
    9 7 8 - 0 - 1 2 - 3 8 5 5 4 1 - 1
This title provides comprehensive coverage of modern gas chromatography including theory, instrumentation, columns, and applications addressing the needs of advanced students and professional scientists in industry and government laboratories. Chapters are written by recognized experts on each topic. Each chapter offers a complete picture with respect to its topic so researchers can move straight to the information they need without reading through a lot of background information.

Chromatography of Steroids

  • 1st Edition
  • Volume 8
  • September 22, 2011
  • Erich Heftmann
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 8 5 8 0 8 - 1

Gas Chromatography of Polymers

  • 1st Edition
  • Volume 10
  • September 22, 2011
  • Victor G Berezkin + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 8 5 8 1 0 - 4

Microcolumn Separations

  • 1st Edition
  • Volume 30
  • September 22, 2011
  • M.V. Novotny + 1 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 8 5 8 3 3 - 3
Edited by two of the pioneers of microcolumn chromatography and written by recognized experts in the field, this book summarizes advances in microcolumn liquid chromatography, capillary supercritical fluid chromatography and microelectrophoresis. Its unique combination of expert knowledge from leading laboratories in the USA, Japan and Switzerland, results in a particularly in-depth and comprehensive coverage of the various aspects of microcolumn separation methods.

Chromatography of Antibiotics

  • 1st Edition
  • Volume 1
  • August 26, 2011
  • Gerald H. Wagman + 1 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 8 5 8 0 1 - 2