Journal of Chromatography A publishes research papers and critical reviews on all aspects of fundamental and applied separation science. The scope includes chromatography and related techniques (e.g. field-flow fractionation, electromigration techniques, hyphenated and other multi-dimensional techniques). Manuscripts on sample preparation methods/techniques and detection techniques, especially mass spectrometry are also considered, principally if they have a substantive chromatographic component. In addition, approaches dealing with the automation and miniaturization of separation techniques, and sample preparation and/or detection in combination with separation techniques are welcomed.Journal of Chromatography A values manuscripts describing fundamental research on all aspects of separation science theory and methodology, instrumental developments and analytical and preparative applications of general interest. In determining the suitability of submitted articles for publication, particular scrutiny is placed on the degree of novelty and significance of the research and the extent it adds to existing knowledge in separation science. Applications should address cutting-edge research questions and present a certain degree of complexity. The journal discourages submissions limited to the analysis of only one or two compounds or those that are straightforward extensions of published methods to new sample matrices. Furthermore, plagiarism and inadvertent lack of citations will be scrutinized extensively, and are a reason for immediate rejection.Journal of Chromatography A applies uniform acceptance criteria to all types of submissions (Full-length Research Papers; Short Communications; Technical Notes; Concept Papers; Review article; Discussions and Tutorials), irrespective of whether these are submitted to Regular Issues, Virtual Special Issues, or Virtual Symposium Special Issues.
CHROMB (Journal of Chromatography B) publishes papers on developments in separation science relevant to biology and biomedical research including both fundamental advances and applications. Analytical techniques which may be considered include the various facets of chromatography, electrophoresis and related methods, affinity and immunoaffinity-based methodologies, hyphenated and other multi-dimensional techniques, and microanalytical approaches. The journal also considers articles reporting developments in sample preparation, detection techniques including mass spectrometry, and data handling and analysis.Development... related to preparative separations for the isolation and purification of components of biological systems may be published, including chromatographic and electrophoretic methods, affinity separations, field flow fractionation and other preparative approaches.Applicati... to the analysis of biological systems and samples will be considered when the analytical science contains a significant element of novelty, e.g. a new approach to the separation of a compound, novel combination of analytical techniques, or significantly improved analytical performance. Areas to be considered include:• The qualitative and quantitative analysis of biopolymers including proteins, monoclonal antibodies, peptides and their post-translational modifications as well as nucleic acids and glycans • The comparative analysis of biological systems using proteomics, genomics, metabolomics, lipidomics and other “omics” approaches • Clinical analysis, metabolism, therapeutic drug monitoring, toxicological analysis, doping analysis, veterinary applications, analysis of environmental contaminants in biological systems • The screening and profiling of body fluids, tissues, cells, biological matrices and systems, analysis of endogenous compounds, biomarkers • Identification of new bioactive compoundsApplication... which utilize published or commercial analytical or preparative protocols with little or no modification or where the results of the application rather than the analytical methodology comprise the major element of novelty of the manuscript should be directed to more specialized journals. Modifications to a previously published method may be considered for a short communication in cases where the improvement in performance is significant. Reports of analytical methods for compounds in early pharmaceutical development often lack general interest and will not be published unless the authors can demonstrate the broader significance of the methodology involved. Quality control analyses of bulk drugs, natural products or pharmaceutical formulations of small molecules are not within scope.
