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Books in Life sciences

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41-50 of 20378 results in All results

Fibroblast Biology

  • 1st Edition
  • January 1, 2030
  • Nicholas Kurniawan + 1 more
  • English
Fibroblast Biology: Development, Differentiation, and Mechanical Regulation in Health and Disease offers a comprehensive treatment of fibroblast biology to cell biologists, biomedical engineers, and research physicians interested in understanding the role these cells play in maintaining organismal homeostasis. Conditions covered include keloid fibroblasts, cancer, neurological diseases, rheumatoid arthritis, diseases in the lungs, kidney, and muscular tissue, including the cardiac muscle. This book is a complete reference that serves as perfect entry-pint for researchers new to this field. Research physicians can benefit from the connections established between cell biology and specific disease states covered.Comprised of three parts, the book opens with an introduction to fibroblasts, covering their roles in the human body, their heterogeneity, profiling, and interactions with the extracellular matrix. The initial part is concluded with an overview of cell mechanics and mechanobiology. Part two delves into the biology of fibroblasts, including signaling networks, activation, proliferation and differentiation, migration, their role in normal wound healing, interactions with other cell types, and the changes in fibroblasts across the organismal lifespan. The final part is dedicated to fibroblasts roles in disease states and therapeutic opportunities.

Biomechanics and Mechanobiology of the Lumbar Spine

  • 1st Edition
  • December 31, 2029
  • Jérôme Noailly
  • English
Biomechanics and Mechanobiology of the Lumbar Spine: Computational Approaches: From Research to In Silico Medicine aims to outline how major decision points—such as goal-adapted numerical approximations—infer in the capability of lumbar spine models to provide valuable cause-and-effect relationships in the study of organ conditions and treatments. The spine presents an astonishing balance between mechanical resistance and flexibility in the human body, provided by complex interactions that are extremely difficult to restore when altered in disease. Given that these interactions are difficult to assess in situ, designing efficient treatments for low back pain remains a grand challenge in medicine. Along with more than 10 years of activity in research, the book's author has explored in-depth the capability of finite element models to capture the functional load transfers within the lumbar spine. Readers of this book will find useful guidelines for model developments in both research and clinical applications.

Brain Metastases in Lung Cancer Patients

  • 1st Edition
  • December 3, 2029
  • Giulia M Stella + 1 more
  • English
Brain metastases in lung cancer patients aims to provide new insights into biology and clinical management of a feared and common disease, recapitulating and dissecting the molecular basis of metastatic brain dissemination from lung cancer. Lung cancer is among the leading causes of death worldwide and is frequently associated to the arousal of brain metastasis, most often discovered at diagnosis. A key role is played by liquid biopsy, as non-invasive informative tool for both diagnosis and monitoring of response to targeted therapies. Molecular mechanisms leading to tumour spreading to brain are almost unknown so that these tragic cases are still lacking effective therapies. The book looks into the epidemiology and clinical approach to brain-metastatic lung cancer, molecular basis of dissemination to the brain, and the novel therapeutic approaches. The book summarizes and analyses the pathogenic mechanisms leading to activation of scatter factor receptor in brain metastatic dissemination from the lungs within the perspective of designing less empirical treatment strategies than those currently used.

Animal Health Sensors and Monitoring Systems

  • 1st Edition
  • December 1, 2029
  • Harshal Arolkar
  • English
Animal Health Sensors and Monitoring Systems focuses on the equipment and implementation of different sensors used for monitoring the health of livestock animals. The book examines how to develop and deploy monitoring systems that can track an animal’s health scenario on a 24/7 schedule, also providing vital information on how to combine the use of multiple sensors to cohesively and comprehensively acquire the most useful data. It is the ideal resource for researchers and academics in precision livestock farming (PLF), but is also a great reference for students and farmers who are interested in combining technological advances with livestock health monitoring methods.

Hydroxyapatite (HAp) for Biomedical Applications

  • 2nd Edition
  • December 1, 2029
  • Michael Mucalo
  • English
Hydroxyapatite (HAp) for Biomedical Applications, Second Edition, is an updated and systematic review of recent research into the science and application of hydroxyapatite in medicine. Hydroxyapatite in the form of hydroxycarbonate apatite is the principal mineral component of bone tissue in mammals. In bioceramics, hydroxyapatite is classed as a bioactive material, which means bone tissue grows directly on it when placed in apposition without intervening fibrous tissue. Hydroxyapatite is hence commonly used as bone grafts, fillers and as coatings for metal implants. The book reviews the fundamentals of hydroxyapatites including materials properties, biocompatibility, and degradation behaviour. It then discusses the latest applications in tissue engineering, drug delivery, and other important biomedical areas.This important new edition provides an up-to-date overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application, including new content on novel technologies, biomorphic hydroxyapatite and more.

The Parathyroids

  • 4th Edition
  • December 1, 2029
  • John P. Bilezikian + 6 more
  • English
Praise for Previous Editions: "...a comprehensive source of information that most endocrinologists will want to have on their bookshelves." --Trends in Endocrinology and Metabolism, 2003 "It represents a significant contribution to the field, and likely will continue to do so for many editions." --Bart L. Clarke, Mayo Clinic, for Doody Publishing Reviews, 2002 Written by world experts, The Parathyroids, Fourth Edition is thoroughly updated to reflect the considerable advances in just about every aspect of parathyroid biology. It continues to be the authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium. This translational resource is invaluable to graduate students, fellows, researchers, and research clinicians in the fields of endocrinology, bone biology, osteology, nephrology, and rheumatology. Since the publication of the previous edition, interest in hypoparathyroidism has intensified with new insights into etiology, epidemiology, molecular genetics, and therapeutics.

Cell-Based Liver Regeneration

  • 1st Edition
  • December 1, 2029
  • Hala M. Gabr + 1 more
  • English
Stem cell therapy is a fast-growing field of medicine with remarkable prospects in a broad spectrum of diseases. Cell-Based Liver Regeneration: Current Aspects and Future Approaches addresses the full spectrum of regenerative medicine in liver diseases. Coverage will include the basic science, current research and a comprehensive review of clinical trials conducted in the field.The book will discuss the various types of stem cells for liver regeneration, presenting the advantages and disadvantages of each type. A review of all aspects of implanting stem cell therapy for the liver, such as: choosing the cell type, the source, laboratory manipulation, dose, route and follow-up. The book concludes with a full discussion of the current clinical trials involving cellular therapy in liver regeneration.Cell-Based Liver Regeneration: Current Aspects and Future Approaches is written for stem cell biologists, liver biologists, hepatologists and graduate students by authors with extensive knowledge in basic, pre-clinical and clinical stem cell research.

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Immunotherapy

  • 1st Edition
  • Volume 5
  • December 1, 2029
  • Kasuya Hideki + 1 more
  • English
Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Immunotherapy discusses current and under investigation treatments in pancreatic cancer. The book presents information on how to combine current therapy with treatment under development and/or in clinical trials in order to improve survival. Chapters review new modalities to cure oncolytic viruses and Bi-specific T cell engager (BiTEs) as future clinical treatments, along with discussions on recent research using those modalities in combination therapy. The book is a valuable source for cancer researchers, oncologists and other members of the medical and biomedical field who are interested in learning more about new therapies.

Seaweed Sustainability

  • 2nd Edition
  • December 1, 2029
  • Brijesh K. Tiwari + 1 more
  • English
Seaweed Sustainability: Food and Non-Food Applications, Second Edition is the leading evidence-based resource for information on the applications of seaweed as a solution to meet an increasing global demand as a sustainable food source. The book uncovers seaweed potential and describes the various sources of seaweed, the role of seaweeds as a sustainable source for human food and animal feeds, and the role of seaweed farming for sustainability. It covers various aspects of seaweeds ranging from harvesting, processing and applications and includes the classification, importance, chemical composition and impact of climate change on seaweed harvesting techniques, processing, conventional and emerging technologies.This new edition is completely updated and includes a range of new products and ingredients obtained for food, feed and fuel applications. In addition, it includes a new chapter on the biorefinery of seaweeds using a zero-waste approach.