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1751-1760 of 14739 results in All results

Post-transcriptional Gene Regulation in Human Disease

  • 1st Edition
  • Volume 32
  • August 12, 2022
  • Buddhi Prakash Jain + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 1 3 0 5 - 8
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 4 2 4 - 6
Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail.

Respiratory Neurobiology

  • 1st Edition
  • Volume 188
  • August 12, 2022
  • Robert Chen + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 1 5 3 4 - 2
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 5 3 5 - 9
Respiratory Neurobiology: Physiology and Clinical Disorders, Part One, Volume 188 is one of two volumes on the neurology of breathing. This volume focuses on the neurophysiology of breathing, while the second volume focuses on pathologies attributable to abnormalities of the neural control of breathing, breathing problems that may occur in neurological diseases, and the neurological complications of respiratory diseases.

Helicase Enzymes Part B

  • 1st Edition
  • August 12, 2022
  • Michael Trakselis
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 9 7 7 3 - 7
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 7 7 4 - 4
Methods in Enzymology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Imaging of Headache, An Issue of Neurologic Clinics

  • 1st Edition
  • Volume 40-3
  • August 11, 2022
  • Sangam Kanekar
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 8 9 7 5 0 - 1
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 9 7 5 1 - 8
In this issue of Neurologic Clinics, guest editor Dr. Sangam Kanekar brings his considerable expertise to the topic of Imaging of Headache. Top experts in the field cover key topics such as headache attributed to disorder of the cranium and base of the skull; role of CT and MRI in evaluation of headache due to paranasal sinus and teeth disorder; imaging of painful ophthalmologic disorders; role of MRI and CT in the evaluation of headache in pregnancy and postpartum period; assessment and imaging of pediatric and adolescent headache; and more. 

Synergistic Approaches for Bioremediation of Environmental Pollutants: Recent Advances and Challenges

  • 1st Edition
  • August 11, 2022
  • Riti Thapar Kapoor + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 1 8 6 0 - 2
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 4 1 4 - 7
Synergistic Approaches for Bioremediation of Environmental Pollutants: Recent Advances and Challenges focuses on the exploitation of various biological treatment technologies and their use to treat toxic contaminants present in industrial effluent and in restoring contaminated sites, which lacks in a more comprehensive manner in existing titles on similar topics available on the global market. The book comprises advanced biotechnologies and updated information, along with sustainable waste management developments and future directions for researchers and scientists working in the field of microbiology.

"Venomous" Bites from "Non-Venomous" Snakes

  • 2nd Edition
  • August 10, 2022
  • Scott A Weinstein + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 2 2 7 8 6 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 2 7 8 7 - 9
"Venomous" Bites from "Non-Venomous" Snakes, Second Edition thoroughly examines the potential hazards associated with bites by non-front-fanged snakes (popularly, but inaccurately, called "rear-fanged snakes"). This diverse group contains approximately 80% of living snake species (approximately 2,900 species). A large proportion of these snakes were previously assigned to the family Colubridae but, as a consequence of expanding systematics investigations, have been split into multiple families and subfamilies. Many of these snakes produce venoms or oral secretions that contain toxins and other biologically active substances. A large variety of non–front-fanged snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical importance of many of these species has been subjected to speculation since the mid-19th century, there is a limited amount of useful descriptive information regarding the real hazard (or lack thereof) of this wide variety of snakes. The first edition of this book provided "one-stop shopping" by offering information regarding their possible toxicity and clinical relevance as well as recommendations for medical management of their bites. The second edition expands and updates the content with detailed information about the effects and medical management of bites by a broad representation of non–front-fanged species. The hypothetical venomous nature of some lizards considered as non-venomous such as the Komodo monitor or dragon and their allies, as well as the medical effects of their bites, is also examined. The dynamic taxonomy of advanced snakes is updated, and the bases for some of these fluid changes are discussed. Likewise, terminology is also updated in order to reflect the ongoing debates regarding the definition of "venom" and the balanced reinforcement of nonmedical criteria used to define the biological basis of the term "venomous."

3D Lung Models for Regenerating Lung Tissue

  • 1st Edition
  • August 10, 2022
  • Gunilla Westergren-Thorsson + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 0 8 7 1 - 9
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 0 8 7 2 - 6
3D Lung Models for Regenerating Lung Tissue is a comprehensive summary on the current state of art 3D lung models and novel techniques that can be used to regenerate lung tissue. Written by experts in the field, readers can expect to learn more about 3D lung models, novel techniques including bioprinting and advanced imaging techniques, as well as important knowledge about the complexity of the lung and its extracellular matrix composition. Structured into 15 different chapters, the book spans from the original 2D cell culture model on plastic, to advanced 3D lung models such as using human extracellular matrix protein. In addition, the last chapters cover new techniques including 3D printing, bioprinting, and artificial intelligence that can be used to drive the field forward and some future perspectives. This highly topical book with chapters on everything from the complexity of the lung and its microenvironment to cutting-edge 3D lung models, represents an exciting body of work that can be used by researchers during study design, grant writing, as teaching material, or to stay updated with the progression of the field.

Hepatobiliary Cancers: Translational Advances and Molecular Medicine

  • 1st Edition
  • Volume 156
  • August 10, 2022
  • Alphonse E. Sirica + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 8 3 9 2 - 1
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 8 3 9 3 - 8
Hepatobiliary cancer refers to primary malignant tumors originating in cells of the liver, bile ducts, and gallbladder. Globally, primary liver cancer, which includes hepatocellular carcinoma (~75 % of all cases) and intrahepatic biliary cancer or cholangiocarcinoma (~10-15 % 0f all cases) is the 6th most commonly diagnosed cancer and 3rd leading cause of cancer deaths worldwide. The vast majority of these highly malignant cancers are diagnosed at an advanced stage where  treatment options are limited and patient survival outcomes are poor. The biological and therapeutic challenges posed by hepatobililiary cancers such as hepatocellular carcinoma (HCC)  and cholangiocarcinoma (CCA) are daunting, emphasizing a critical need to review and assess current and evolving basic, translational, and clinical research focused on addressing the critical obstacles that continue to limit progress towards achieving significant improvements in HCC and CCA clinical management and patient survival outcomes. Towards this goal, this special edition of Advances in Cancer Research is focused on providing  a comprehensive, timely and authoritative reviews covering such topics of significant scientific and clinical relevance, including hepatobiliary cancer risk mechanisms and risk-predictive molecular biomarkers; causes and functional intricacies of inter- and intratumor heterogeneity; novel insights into the role of tumor microenvironment and key signaling pathways in  promoting hepatobiliary cancer progression, therapeutic resistance and immunosuppression; emerging biomarkers of HCC and CCA prognosis;  advances in molecular genomics for personalizing tumor classification and targeted therapies;  innovative preclinical cell culture modeling for hepatobiliary cancer drug discovery; and current and emerging trends in hepatobiliary cancer molecular therapeutic targeting and immunotherapies.

Fish Roe

  • 1st Edition
  • August 9, 2022
  • Alaa El-Din A. (Aladin) Bekhit
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 9 8 9 3 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 1 7 6 - 0
Provides comprehensive coverage of the components available in fish roe and highlights their biological and nutritional effects as well as their sensory and safety attributes. Fish Roe: Biochemistry, Products, and Safety describes various components available in fish roe and introduces their biological and nutritional effects. In addition to addressing biological and nutritional effects, this book also explores fish roe products and their safety while also providing coverage of the bioactives that are naturally available in fish roe or generated during processing, thereby outlining the maximum benefits that can be obtained from this natural resource. Beginning with the introduction of fish roe production procedures worldwide, this book further explores the processing of traditional fish roe products from Europe, Asia, and the Middle East, where fish roe is frequently consumed. This book also discusses the sensory and safety attributes of fish roe and will be a comprehensive reference for food scientists, chemists, food process engineers, developers, researchers, and students in the field of seafood science.

Methods in Stem Cell Biology - Part B

  • 1st Edition
  • Volume 171
  • August 9, 2022
  • Ilio Vitale + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 0 0 1 8 - 8
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 0 0 1 9 - 5
Methods in Cancer Stem Cell Biology: Part B, Volume 171 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

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