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Elsevier

Books in Life sciences

  • Research Methods

    Principles in Practice
    • 1st Edition
    • Samy A. Azer
    • English
    Research Methods: Principles in Practice provides undergraduate research students, novice researchers, and instructors with engaging approaches to understanding research and how to apply and use different research methods. The book helps students develop skills in conducting literature searches, reading literature, designing research projects, selecting research methods, collecting data, interpreting findings, and writing research reports. Topics covered include research philosophy; study design; developing research questions; the use of theories in research; research ethics; qualitative, quantitative, and mixed-methods research; social media research; and writing a research report. The book provides practical activities, model answers at the end of each chapter, and further reading, enabling students to gain a deeper understanding of research methods and to master their application.

  • Artificial Intelligence in Point-of-Care Nanobiosensors Technology

    Enhancing Disease Diagnostics and Improved Healthcare Outcomes
    • 1st Edition
    • Tharmaraj Vairaperumal + 2 more
    • English
    Artificial Intelligence in Point-of-Care Nanobiosensors Technology: Enhancing Disease Diagnostics and Improved Healthcare Outcomes delves into the revolutionary integration of artificial intelligence (AI) with nanobiosensors to elevate point-of-care (POC) diagnostics for both communicable and non-communicable diseases. Readers will find insightful chapters covering topics ranging from foundational AI and machine learning techniques to specific applications in cardiovascular disease, diabetes, cancer, chronic respiratory ailments, and infectious diseases. Each chapter not only highlights recent breakthroughs in nanobiosensors but also emphasizes the pivotal role of AI in enhancing diagnostic accuracy and facilitating personalized health interventions. Additional discussions around regulatory considerations and the future landscape of AI in biomedical research make this an essential read for those navigating this rapidly evolving field. This book primarily targets researchers and professionals engaged in the interdisciplinary realms of AI, nanomaterials, and biomedical sciences. By providing a critical understanding of emerging AI-based diagnostic technologies and their applications in POC settings, this book fosters collaboration across diverse scientific domains.

  • Sustainable Thermal Processing in Food Manufacturing

    Ohmic, Microwave and Induction Technologies
    • 1st Edition
    • Ravi Pandiselvam + 2 more
    • English
    Sustainable Thermal Technologies in Food Processing: Ohmic, Microwave, and Induction Technologies offers an authoritative resource on advanced thermal processing technologies critical for modern food preservation and extraction. Addressing the limitations of conventional thermal methods, this reference explores energy-efficient, high-quality, and environmentally responsible heating techniques. The chapters cover fundamental engineering principles, food safety mechanisms, system design, process control, and digital innovations including AI and IoT integration. Specialized topics include drying, pasteurization, cooking, bioactive compound extraction, thawing, fermentation, and nutritional impacts. The text also presents industrial-scale applications, regulatory frameworks, and future research directions, providing a holistic understanding of these emerging technologies. This book equips industry professionals, academic researchers, and students with critical insights to select, model, and implement sustainable thermal processes. It supports innovation in food manufacturing by delivering comparative evaluations, scale-up challenges, and sustainability assessments, fostering adoption of green technologies for improved food safety, quality, and environmental performance.

  • Electrochemical Sensors and Biosensors for Food Safety

    Fundamentals, Nanomaterials, and Real-World Applications
    • 1st Edition
    • J. Tharini + 1 more
    • English
    Electrochemical Sensors and Biosensors for Food Safety: Fundamentals, Nanomaterials, and Real-World Applications is a vital resource addressing the urgent need for highly sensitive detection of organic, inorganic, and biological pollutants in food and water. Detecting hazardous molecules at nanomolar levels is crucial for ensuring public health and food safety, yet current methods often lack the sensitivity and specificity required for early detection. This book explores how advanced nanomaterials and flexible substrate matrices enhance the performance of electrochemical sensors, providing accurate, rapid, and cost-effective solutions for detecting contaminants in complex samples. The book covers essential topics, including the fundamentals of electrochemical sensing, nanocomposite synthesis, computational modeling, fabrication of flexible electrodes, and integration with artificial intelligence and IoT technologies. It discusses applications in detecting pesticides, heavy metals, veterinary drugs, food additives, and microbial pathogens, as well as the regulatory frameworks governing their use. Case studies and future directions highlight the potential for developing smart, reusable sensors that can be implemented in real-world food safety monitoring systems.Electrochemi... Sensors and Biosensors for Food Safety: Fundamentals, Nanomaterials, and Real-World Applications serves as an indispensable guide for researchers, industry professionals, and policymakers committed to advancing food safety technologies, protecting public health, and promoting innovative solutions for sustainable food systems.

  • Brain Point-of-Care Ultrasound

    Practical Guide and Protocols
    • 1st Edition
    • Camilo N. Rodríguez + 6 more
    • English
    Brain Point-of-Care Ultrasound: Practical Guide and Protocols explores brain hemodynamics and parenchyma examination, providing an orderly and protocolized approach that facilitates individualized clinical decisions with ease. Covering ultrasound configuration, in-depth anatomical knowledge, and advanced parameters, this guide aims to integrate brain ultrasound seamlessly into the Point-of-Care Ultrasound (POCUS) modality, addressing the critical need for comprehensive patient assessment. From basic principles to specialized clinical situations, each section of this guide is meticulously crafted to empower practitioners with practical insights. Chapters explore Doppler spectral wave interpretation, angle correction nuances, autoregulation dynamics, and non-invasive pressure estimations, among others, thus enabling precise monitoring and targeted decision-making. With a focus on integration across disciplines and specialties, this book bridges the gap between classical pathology and contemporary practice, positioning brain ultrasound as a pivotal tool in the armamentarium of modern critical care.

  • Bioactive Compounds

    Mechanisms, Challenges and Strategies for Bioaccessibility and Bioavailability
    • 1st Edition
    • Cristobal Noe Aguilar + 3 more
    • English
    Bioactive Compounds: Mechanisms, Challenges and Strategies for Bioaccessibility and Bioavailability covers nutrition, food science, and pharmacology, elucidating the intricate dynamics of bioactive compounds and their impacts on human health. This comprehensive volume delineates the crucial differences between bioaccessibility and bioavailability, providing insights into their implications for health outcomes. Readers will explore the behavior of key classes of bioactive compounds, including polyphenols, carotenoids, and peptides, as well as their sources and interactions within the food matrix. The book further examines the essential role of gut microbiota in absorption processes, highlighting how these interactions can influence bioactive compound efficacy in the human body.Sections not only discuss the mechanisms of absorption, distribution, metabolism, and excretion (ADME) of bioactive compounds but also introduce cutting-edge tools and strategies designed to enhance their bioaccessibility and bioavailability.

  • Plant Nutrient Strategies for Abiotic Stress Resilience

    • 1st Edition
    • Mamdouh A. Eissa
    • English
    Plant Nutrient Strategies for Abiotic Stress Resilience presents a cutting-edge exploration of how nutrient strategies can enhance crop resilience in the face of increasing abiotic stresses such as drought, salinity, heat, cold, and nutrient-poor soils. Through 18 comprehensive chapters authored by leading experts in plant nutrition and stress physiology, the book bridges fundamental scientific knowledge with practical agronomic applications. Maintaining crop productivity in the face of abiotic stressors such as drought, salinity, nutrient depletion, and climate variability continues to challenge crop producers around the world. At the same time, they need to ensure environmentally sustainable nutrient management in diverse and often fragile ecosystems. Many lack access to integrated, up-to-date knowledge that combines soil-plant nutrient dynamics with real-world strategies to combat stress in crops. From nutrient uptake mechanisms under stress conditions to advanced innovations such as nano-fertilizers and genetic approaches for nutrient efficiency, Plant Nutrient Strategies for Abiotic Stress Resilience offers an essential, science-based toolkit for researchers, students, consultants, and policymakers aiming to secure sustainable crop production in a changing climate.

  • Asiatic-Pacific Ticks

    Species of Medical and Veterinary Importance
    • 1st Edition
    • Ze Chen + 1 more
    • English
    Asiatic-Pacific Ticks: Species of Medical and Veterinary Importance provides the most comprehensive and updated research on the taxonomy, biology, and bionomics of tick species native to the Palearctic and Oriental zoogeographic regions. It synthesizes all current research on each species using global perspectives, as these species begin to spread beyond their native habitats.Written and edited by international experts on the ticks of eastern Asia, this book covers the 12 primary species, including the Asian longhorned tick and those under the Hyalomma genus. Each chapter begins by discussing the species’ classification history, followed by identification descriptions for all active life stages, and a detailed discussion of biology and bionomics. The chapters end with a discussion of pathogenic agents associated with each species and their context for human and animal ecology.Asiatic-Paci... Ticks: Species of Medical and Veterinary Importance is a vital resource for entomologists, both in human-medical and veterinary focuses. Public health personnel and parasitologists tracking diseases in tick species will also find this useful.

  • The Autism Spectrum

    Identification, Understanding, and Treatment in Global Context
    • 1st Edition
    • Matthew K. Belmonte + 1 more
    • English
    The Autism Spectrum: Identification, Understanding, and Treatment in Global Context provides an update to the basic and clinical sciences of autism with an understanding of how research and clinical treatments are affected by recent shifts of focus: from diagnostic categories to symptomatic dimensions, from provider-centered to patient-centered treatment approaches, from high-resource, individualistic country insights to those contributed from global cultures.This volume discusses the field’s current state, whence it has come, where it is going, and how to get there. The volume weds basic and clinical understandings, state-of-the-art multivariate analyses, historical and cross-cultural information and relevance, and a patient-centered focus.

  • Nutritional and Health Aspects of Food in Oceania

    • 1st Edition
    • Diana Bogueva + 1 more
    • English
    Nutritional and Health Aspects of Food in Oceania provides an analysis of traditional and ethnic foods from Australia, New Zealand, Fiji, Papua New Guinea, Tonga, Hawaii, Samoa, Tuvalu, Solomon Islands, and New Caledonia. The book addresses the history of use, origin, composition, preparation, ingredient origin, nutritional aspects, and effects on health for various foods and food products in each of these countries. In addition, it presents both local and international regulations while also providing suggestions on how to harmonize these regulations to promote global availability of these foods.

  • Healthcare 4.0

    Pharmaceutical Advancement in the Digital Age
    • 1st Edition
    • Atheer Awad + 1 more
    • English
    Healthcare 4.0: Pharmaceutical Advancement in the Digital Age is a well-structured and easy to understand book that discusses digital health technologies in context of their pharmaceutical applications and the future they hold for this sector. The contents of the book are structured in four parts, covering digital health, software technologies, hardware technologies and the outlook and impact of these innovations to pharmaceutical care. Topics covered include artificial intelligence (AI) and machine learning, blockchain, computational modelling, Telemedicine and Telepharmacy, and virtual/augmented/mi... reality and associated hardware (such as sensors, robotics, smartphones and 3D printing).This book is the perfect resources for academics and corporate researchers in pharmacy, pharmacists, physicians and pharmacy technicians to better understand and position themselves to benefit from the technological developments impacting pharma

  • Decision Neuroscience

    • 2nd Edition
    • Jean-Claude Dreher
    • English
    Decision Neuroscience: An Integrative Perspective, Second Edition, Volume Two presents the most recent and compelling lesional, neuroimaging, electrophysiological... and computational studies in combination with hormonal and genetic studies that have led to a clearer understanding of the neural mechanisms behind reward and decision-making. The neural bases of reward and decision-making processes are of critical interest to scientists because of the fundamental role that reward plays in a number of behavioral processes (such as motivation learning, and cognition), and because the neural bases have theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders.This book provides a comprehensive update on groundbreaking work that addresses fundamental questions about the nature of behavior, including how does the brain process reward and how does it make decisions when facing multiple options? It features entirely new content, as well as expanded coverage on drug and behavioral addiction and the role of subthalamus stimulation in neurological disorders and neuroeconomics.

  • Virtual Possibilities

    Extended Reality as Assistive Technology for Inclusive Care
    • 1st Edition
    • Samiya Khan
    • English
    Virtual Possibilities: Extended Reality as Assistive Technology for Inclusive Care provides invaluable insights for researchers and related medical professionals into the transformative potential of virtual reality as a technological aid. The book navigates through the diverse applications of virtual reality in healthcare, transcending traditional uses such as medical training and therapeutic interventions. It is a dedicated examination of virtual reality's role in social care, addressing the unique needs of individuals across the spectrum, from differently abled individuals and children with learning disabilities to those grappling with disorders, trauma, and the elderly. It presents the state-of-the-art in this field, acting as a bridge, facilitating the translation of theory into practice and fostering ongoing research. Users will find this to be a valuable resource for researchers, professionals, and policymakers interested in the future applications of virtual reality in healthcare and social care.

  • Intelligent Gait Assistive Technologies

    Gait Biomechanics and Machine Learning Applications in Rehabilitation and Injury Prevention
    • 1st Edition
    • Rezaul Begg + 1 more
    • English
    Intelligent Gait Assistive Technologies: Gait Biomechanics and Machine Learning Applications in Rehabilitation and Injury Prevention brings together contemporary research and applications to show how gait biomechanics combined with machine learning can be used to develop techniques to provide safer, more mechanically efficient locomotion to individuals with significant visual, musculoskeletal, or neurological deficits. Developments in gait rehabilitation and injury prevention outlined in this book will contribute to improved quality of life for individuals with gait-related impairments, with a major contribution to medical cost savings due to reduction in falls.Researchers, engineers, and students in biomedical engineering and biomechanics will find this a welcomed reference in better understanding the role of machine learning and intelligent technologies in the advancement of gait rehabilitation and injury reduction to both impaired and healthy individuals.

  • Sustainable Solutions for Food Waste

    From Recovery to Resource Efficiency
    • 1st Edition
    • Gulsun Akdemir Evrendilek
    • English
    SSustainable Solutions for Food Waste: From Recovery to Resource Efficiency examines the magnitude, causes, and environmental impacts of food waste and presents sustainable strategies for its reduction, recovery, and valorization. The book highlights innovative technologies and practical approaches for transforming food and agricultural waste streams into valuable products and resources.Featuring contributions from experts in the field, it provides comprehensive perspectives on waste generation, management, utilization, and valorization across diverse food and agricultural industries, including grape and winery, fruit juice, olive and olive oil, tea and coffee, brewery and distillery, dairy, citrus, meat, seafood, seaweed, tropical fruits, vegetables, tuberous plants, rice, and medicinal and aromatic plants.Organized into four sections, the book addresses food waste, sustainability, valorization, and resource efficiency. Section 1 introduces the magnitude, causes, environmental impacts, and sustainable management of food waste. Section 2 focuses on waste from major food-processing industries. Section 3 explores waste utilization and valorization from plant-based and agricultural sources. Section 4 examines innovative technologies, circular economy approaches, resource recovery, sustainable food-waste management, and business models for resource efficiency.

  • Exploring Infant Cry

    Medical and Technical Analysis and Signal Processing Perspectives
    • 1st Edition
    • Carlos Alberto Reyes Garcia + 3 more
    • English
    Exploring Infant Cry: Medical and Technological Analysis and Signal Processing Perspectives is a comprehensive exploration of the latest medical and technical advancements in the study of infant crying. This book presents a unified approach that integrates medical insights and computational techniques for analyzing and classifying cries, aiming to enhance diagnostic capabilities. Authored by experts, it emphasizes the growing significance of cry analysis as a powerful, non-intrusive tool for identifying pathologies from the earliest stages. As the field expands, researchers and clinicians are offered innovative perspectives and practical solutions for interpreting and understanding why babies cry. The book also explores the connection between infant cries and language development, as well as the communicative importance of these signals in human interaction. Addressing gaps in routine neonatal application, the book compiles recent advancements in signal processing, Artificial Intelligence, and soft computing for cry classification. This makes it a valuable resource for biomedical researchers, doctors, and clinicians seeking to deepen their knowledge of the acoustic, neurophysiological, and linguistic aspects of infant crying.

  • Avian Models of Development

    • 1st Edition
    • Volume 173
    • English
    Avian Models of Development provides practical and experimental approaches for using avian systems to study developmental processes. It covers key methods, model applications, and emerging techniques that support research in embryogenesis, tissue formation, gene function, and developmental mechanisms.

  • Integrated Pest Management

    Current Concepts and Ecological Perspective
    • 2nd Edition
    • Dharam P. Abrol
    • English
    Integrated Pest Management: Current Concepts and Ecological Perspective, now in its second edition, presents an overview of alternative approaches to traditional pest management practices, from biological control to biotechnologies and beyond. Significant scientific and technological advances have been made in the past decade, creating new strategies for pest control and crop protection without harming the environment. Integrated Pest Management, 2nd edition is updated with the latest advances in this crucial field, including key issues in IPM such as insecticide resistance and invasive species, as well as novel and advanced methods for tackling them, including the use of artificial intelligence, digital monitoring, and genomic approaches such as RNA interference.Opening with three new chapters on the biological and ecological foundations of IPM, Integrated Pest Management: Current Concepts and Ecological Perspective, Second Edition is an ideal resource for a wide range of readers. Case studies throughout and discussion questions at the end of each chapter make this book ideal for graduate and advanced undergraduate students in entomology and crop science. Early career researchers in these fields, as well as those working in adjacent fields, will also benefit from this well-organized, practical guide to the growing field of IPM.Case studies throughout and discussion questions at the end of each chapter make this book ideal for graduate and advanced undergraduate students in entomology and crop science. Early career researchers in these fields, as well as those working in adjacent fields, will also benefit from this well-organized, practical guide to the growing field of IPM.

  • Cold-Adapted Enzymes

    Biochemistry and Biotechnology
    • 1st Edition
    • Diego Gomez-Casati + 1 more
    • English
    Cold-Adapted Enzymes: Biochemistry and Biotechnology provides a cutting-edge investigation into the molecular mechanisms, structural dynamics, and regulatory pathways of enzymes adapted to cold environments.Beyond classical microbiology, the book explores cold adaptation from psychrophilic bacteria and Antarctic fungi to microalgae, plants, and mammalian cell physiology. It provides biochemistry insights into carbohydrate (amylases, glucoamylases) and lipid metabolism, proteases, and redox enzymes, alongside the roles of molecular chaperones and prokaryotic proteomics. A key highlight is its focus on next-generation biotechnology, featuring AI-driven protein design, advanced computational modeling, and structural bioinformatics. Bridging foundational science with market reality, the volume explores applications from organic waste valorization to industrial biocatalysis, analyzing the global patent landscape and commercial players.As the latest volume in the Foundations and Frontiers of Enzymology series, this book is an indispensable reference for researchers across biochemistry, biotechnology, structural biology, and microbiology.

  • Basics of Sleep Technology

    Fundamentals of Sleep Technology
    • 1st Edition
    • Ravi Gupta + 2 more
    • English
    Basics of Sleep Technology: Fundamentals of Sleep Technology covers the critical elements of sleep and sleep technologies. The book gives a thorough understanding of sleep physiology, neurophysiological concepts, the principles of operation of the numerous equipment types used to diagnosis sleep disorders, and contemporary methodologies for diagnosing sleep disorders. As sleep professionals must understand the fundamentals of signal creation, acquisition principles, and data grading from a sleep diary, actigraphy, and polysomnography, this book provides all of this and more to anyone wishing to develop a comprehensive understanding of sleep.The book underscores that sleep medicine and technology are dynamic and rapidly growing medical specialties, and that one must stay up with the newest innovations in the area, but not at the price of the fundamentals. Users will find a solid background on cutting-edge advances in sleep medicine, diagnostics, monitoring, and therapeutics.

  • Gallin and Ognibene's Principles and Practice of Clinical Research

    • 5th Edition
    • John I. Gallin + 2 more
    • English
    Gallin and Ognibene’s Principles and Practice of Clinical Research, 5th Edition is the definitive text on clinical research, written by internationally recognized experts in their field, from the US National Institutes of Health, the US Food and Drug Administration, academia, and global researchers. The new edition contains fully updated chapters, with more than 50 new authors and 15 new chapters. The book continues a strong emphasis on study design and biostatistics in clinical research, with new chapters containing fresh information on a variety of topics, including chapters on how to engage a full range of research participants and research opportunities for people involved in patient care including surgeons, pharmacists, and other clinical researchers. For the international researcher, two new chapters detail international clinical research experiences in South Africa and India. As with the 4th edition, the new edition provides readers with summary questions and answers after select chapters.

  • Biofabrication Technologies for Tissue and Organ Engineering and Manufacturing

    • 1st Edition
    • Lorenzo Moroni + 1 more
    • English
    Biofabrication Technologies for Tissue and Organ Engineering and Manufacturing is the fourth volume in the Regenerative and Transplant Medicine Series. The book offers a range of benefits tailored to its diverse audience. For students in biomedical engineering and related fields it provides a comprehensive understanding of biofabrication technologies in tissue and organ engineering and preparing them for future careers. Researchers and scientists in tissue engineering benefit from staying current with the latest advancements, fostering interdisciplinary collaboration, and offering practical insights for experimental design. Clinicians and healthcare professionals gain a deeper understanding of biofabrication applications, improving patient care and staying informed about emerging technologies. Industry professionals in medical devices and biofabrication find valuable insights for product development and market opportunities, while educators use the textbook to enrich curricula and provide real-world applications for students. Regulatory affairs specialists benefit from updates on ethical considerations and compliance in biofabrication, and government officials gain insights into shaping policies for responsible innovation.The authorship is intentionally diverse, encompassing professionals from various backgrounds, including gender, ethnicity, and geographical location. The authors explore applications of biofabrication technologies across different cultural and medical contexts, including voices from underrepresented groups in the fields of biomedical engineering and biofabrication.

  • Interstitial Lung Diseases

    New Frontiers in Research and Clinical Applications
    • 1st Edition
    • Carlo Vancheri + 1 more
    • English
    Interstitial Lung Diseases: New Frontiers in Research and Clinical Applications is the book that professionals working with Interstitial Lung Diseases (ILDs) have been waiting for. ILDs encompass a complex group of diseases, characterized by varying degrees of inflammation and fibrosis in the lungs, leading to diverse clinical presentations and subtle differences in imaging findings. This complexity makes diagnosis challenging for pulmonologists, radiologists, and researchers, who must stay updated on evolving pathophysiology, diagnostic innovations, and new classification systems. This comprehensive, invaluable resource integrates the pathogenic, functional, clinical, and radiological aspects of ILDs, providing clinicians with a practical tool for patient care. This book elucidates the distinguishing features of different ILDs, empowering readers to navigate the diagnostic and therapeutic landscape confidently. It offers a practical, step-by-step approach to diagnosing ILDs and understanding their nuances, structured around the latest scientific evidence. Further, it covers etiology, epidemiology, pathogenesis, diagnostic processes, and therapeutic options, incorporating diagnostic and treatment algorithms to serve as both a reference and a practical guide for clinical decision-making. By filling gaps in the literature, “Interstitial Lung Diseases: New Frontiers in Research and Clinical Applications” equips respiratory professionals with the knowledge and skills necessary to enhance diagnostic accuracy, improve patient management, and foster ongoing innovation in the study of ILDs.

  • The Human Electroretinogram

    A Diagnostic Guide
    • 1st Edition
    • Benedetto Falsini
    • English
    The Human Electroretinogram: A Diagnostic Guide describes the physiological basis and clinical applications of the human electroretinogram (ERG). Several sub-types of ERGs are evoked by Full-Field stimuli, with characteristics that depend critically on the properties of the stimulus. This book discusses the human retina’s high sensitivity to light and its ability to respond robustly to even single quanta of light. Specifically, it clarifies that the major components of flash ERG, the a-wave and b-wave, are generated by photoreceptors and bipolar cells, respectively. This book explores how changes in light intensity, adaptation, and temporal frequency can alter the contributions of different retinal generators (e.g., rods, cones, and bipolar cell subtypes). In addition to Full Field ERG, other important diagnostic electroretinograms including focal, multifocal, and pattern ERGs are clarified. This book uniquely illustrates the combined use of these ERG tools, allowing clinicians to perform a functional dissection of the retina and achieve a layer-by-layer analysis.The approach of The Human Electroretinogram: A Diagnostic Guide correlates with retinal layer evaluations performed using modern multimodal imaging techniques, such as optical coherence tomography (OCT). ERG analysis exemplifies a critically important tool for early diagnosis, follow-up, and treatment monitoring of retinal diseases involving different retinal layers. This book is essential in providing ophthalmological professionals with the know-how to manage the interplay between these numerous elements.

  • Animal Cognition

    Fundamentals, Models, and Therapeutic Advances
    • 1st Edition
    • Shampa Ghosh + 3 more
    • English
    Animal Cognition: Fundamentals, Models, and Therapeutic Advances provides a comprehensive overview of cognitive processes in various animal species, spanning fundamental concepts, species-specific studies, and therapeutic applications. Sections cover the foundation of animal cognition, including definitions, key concepts, and an overview of cognitive abilities, such as memory, problem-solving, and learning, delve deeper into the cognitive processes in mammals, birds, and marine animals, and more, and review the latest technological advancements in studying cognition, such as neuroimaging, machine learning, and virtual reality. With a multidisciplinary approach, this volume highlights current research while identifying gaps for future exploration, and will be of interest to researchers involved in animal cognition and behavioral neuroscience.

  • Neurological and Neuropsychiatric Disorders

    Substance Use and Addictive Behaviors
    • 1st Edition
    • Alexander Baldacchino + 1 more
    • English
    Neurological and Neuropsychiatric Disorders: Substance Use and Addictive Behaviors is an essential resource that delves into the intricate relationship between substance use, addictive behaviors, and their profound impact on neurological and neuropsychiatric health. The book presents a comprehensive examination of the various disorders and conditions that arise from, or are exacerbated by, substance use and addictive behaviors, offering a multidisciplinary approach to understanding these complex interactions. This volume provides a detailed and updated exploration of the neurological and neuropsychiatric consequences of substance use and addictive behaviors.By compiling the latest research and clinical insights, this volume aims to fill a critical gap in the existing literature, which often treats substance use disorders and neurological impacts as separate entities. This integrated approach is crucial for both researchers and clinicians who need a thorough understanding of the co-morbidities associated with addiction. This book solves the problem of fragmented knowledge by offering a unified perspective that is crucial for developing effective treatment strategies and understanding the full spectrum of addiction-related disorders.

  • Protein-Based Hydrogels

    Exploring the Roles of Protein Hydrogels in Membrane-less Organelles, Disease Mechanisms, and Therapeutic Applications
    • 1st Edition
    • Vladimir N. Uversky + 1 more
    • English
    Protein-Based Hydrogels: Exploring the Roles of Protein Hydrogels in Membrane-less Organelles, Disease Mechanisms, and Therapeutic Applications presents a comprehensive overview of natural and engineered protein hydrogels, examining their critical roles in cellular organization, disease pathology, and therapeutic innovation. This book contributes unique value by integrating fundamental biology, cutting-edge biotechnology, and translational biomedical science to address emerging questions about protein phase separation and gelation. Structured into three sections, the book begins by exploring the physiological functions of protein hydrogels in phase-separated organelles, cellular stress sensing, memory formation, and compartmentalization... It then investigates the pathological consequences of hydrogel dysregulation, including their roles in neurodegenerative diseases, cancer, and viral infections. Finally, it examines biomedical applications such as controlled drug delivery, regenerative medicine, biosensing, and the design of synthetic organelles. Each chapter is contributed by a leading expert, offering multidisciplinary perspectives from biochemistry, molecular biology, bioengineering, and medical research. This book is a valuable resource for academic researchers, graduate students, and professionals working in protein engineering, structural biology, molecular medicine, and pharmaceutical sciences. It supports readers in understanding the full spectrum of protein hydrogel biology—from cell physiology to disease mechanisms and therapeutic design—making it especially relevant for those interested in neurodegeneration, cancer biology, and translational bioengineering.

  • Accurate Results in the Clinical Laboratory

    A Guide to Error Detection and Correction
    • 3rd Edition
    • Amitava Dasgupta + 1 more
    • English
    Accurate Results in the Clinical Laboratory:A Guide to Error Detection and Correction, 3rd Edition continues to be an in-depth resource of common sources of errors in clinical laboratories. It provides strategies to avoid pre-analytical errors, including patient preparation, specimen collection, and anticoagulant use and Insights into major sources of pre-analytical errors such as sample processing and specimen misidentification. This book is an essential reference for professionals and students aiming to enhance accuracy and reliability in clinical laboratory testing. This new edition has fully updated chapters and new information on how to eliminate lab errors including avoiding post analytic phase of reporting results through laboratory informatics system. This is a guide for laboratory professionals and clinicians regarding sources of errors and misinterpretation in the clinical laboratory and how to resolve such errors and identify discordant specimens. Accurate laboratory result interpretation is essential for patient safety. This book is intended as a practical guide to laboratory professionals and clinicians who deal with erroneous results on a regular basis.

  • Solvent Interaction Analysis

    Physical Chemistry and Analytical Applications of Aqueous Two-Phase Systems
    • 1st Edition
    • Boris Y. Zaslavsky + 1 more
    • English
    Solvent Interaction Analysis: Physical Chemistry and Analytical Applications of Aqueous Two-Phase Systems explores Solvent Interaction Analysis (SIA) technology, a cutting-edge approach for protein characterization and proteomics in biological fluids. The book considers a broad spectrum of topics, from fundamental principles such as phase separation, blood-tissue distribution, and posttranslational protein modifications to advanced clinical applications for early detection of various malignancies, neurological disorders, and other diseases. The book opens with an introduction to aqueous two-phase system (ATPS), considering different types of ATPS, hydrophobic and electrostatic properties, and mechanisms of liquid-liquid phase separation, before moving on to specific properties of phases such as solute-water interaction and blood-tissue distribution, and analysis of partitioning individual proteins. It then explores solvent interaction analysis, investigating diagnostic applications and biomarker discovery. Final chapters explore fundamental consequences of ATPS-based analysis and its future opportunities.This comprehensive guide offers a detailed overview of aqueous two-phase systems from foundational knowledge to the latest developments in the field, and is an essential reference for students, researchers and practitioners across a wide range of disciplines, including biophysics, analytical and medicinal chemistry, proteomics, structural biology, pharmaceutical science, and biotechnology.

  • AI-Driven Pharmaceutical Manufacturing

    Regulatory Innovation for Industry 5.0
    • 1st Edition
    • Vivek P. Chavda + 3 more
    • English
    AI-Driven Pharmaceutical Manufacturing: Regulatory Innovation for Industry 5.0 addresses the critical intersection of artificial intelligence, regulatory compliance, and human-centric innovation in drug product manufacturing. This reference responds to the growing need for advanced technological integration in pharmaceutical production, focusing on how AI and machine learning can optimize manufacturing processes while meeting stringent regulatory demands globally. It fills the knowledge gap for professionals navigating the complex landscape of Industry 5.0 in pharma. The book is structured into five key sections covering digital and regulatory foundations, pharmaceutical manufacturing practices, AI applications in drug development, regulatory compliance challenges, and future trends including cybersecurity and supply chain optimization. Each chapter provides foundational concepts, detailed methodologies, case studies, and practical implementation strategies, ensuring readers gain a thorough understanding of AI's role in pharmaceutical manufacturing. "AI-Driven Pharmaceutical Manufacturing" benefits professionals in manufacturing, regulatory affairs, quality assurance, and technology leadership by delivering actionable knowledge to implement AI/ML responsibly. It equips readers to overcome regulatory challenges, optimize production workflows, and foster sustainable human-machine collaboration, making it an indispensable resource for advancing pharmaceutical manufacturing into the Industry 5.0 era.

  • Biophysical Nutrition

    How Environments Shape Diets from Earth to Space
    • 1st Edition
    • Vidyullatha Peddireddy + 1 more
    • English
    In an era where human exploration extends beyond Earth and personalized nutrition has become a cornerstone of health, understanding how environments influence dietary needs is paramount. Biophysical Nutrition: How Environments Shape Diets from Earth to Space bridges the divide between nutritional science and biophysics and sheds light on the physical principles that govern digestion, absorption, and metabolism across terrestrial and extraterrestrial settings.Divided into three comprehensive sections, Biophysical Nutrition: How Environments Shape Diets from Earth to Space explores foundational concepts such as thermodynamics of metabolism and membrane biophysics, while addressing adaptation mechanisms to extreme environments including microgravity and spaceflight. It highlights innovative approaches to space agriculture, dietary delivery systems, and alternative proteins designed for long-duration missions. Emphasizing translational applications and ethical considerations, this book equips researchers and professionals with the tools to design personalized nutrition strategies informed by biophysical modeling for challenging environments including Space. Essential for researchers in nutrition science, biomedical fields, and planetary science, this work paves the way for future innovations in dietetics from Earth’s most challenging environments to celestial habitats.

  • Microbiome-Modulating Strategies in Diabetic Wound Healing

    • 1st Edition
    • Jeena Gupta + 2 more
    • English
    Microbiome-Modulatin... Strategies in Diabetic Wound Healing provides researchers with an in-depth analysis of the wound microbiome’s role in diabetic foot ulcers and chronic wound pathology. This reference elucidates microbial dysbiosis, biofilm formation, and host–microbe interactions that exacerbate impaired healing in diabetic patients. It critically evaluates emerging microbiome-targeted interventions—includ... probiotics, bacteriophages, antimicrobial peptides, and nanotechnology-enabl... drug delivery—supported by the latest molecular, microbiological, and clinical research. The book integrates advanced diagnostic methodologies such as next-generation sequencing and bioinformatics to facilitate precise microbial profiling and personalized therapeutic design. By bridging mechanistic insights with translational and clinical evidence, this resource equips diabetic researchers with comprehensive knowledge to innovate and optimize microbiome-based strategies, ultimately aiming to reduce infection rates, combat antibiotic resistance, and improve regenerative outcomes in diabetic wound management.

  • Autophagy and Neurodegeneration

    • 1st Edition
    • Volume 409
    • English

  • Dietary Fiber

    Extraction, Properties and Modifications for Food Applications
    • 1st Edition
    • Tabli Ghosh + 1 more
    • English
    Dietary Fiber: Extraction, Properties and Modifications for Food Applications is an essential resource for food scientists and researchers seeking to understand the full potential of dietary fiber in the food industry. The book highlights fiber's various sources and critical health benefits, including detailed discussions on extraction techniques, characterization, and functional properties, equipping readers with the knowledge needed to innovate and enhance food formulations. Sections explore advanced topics such as nano and microencapsulation techniques that enhance fiber stability and bioavailability and the role of dietary fiber in gut health, microbiome modulation, and broader health implications.As the demand for healthier, functional foods grow, this book addresses the challenges of modifying dietary fiber to improve its solubility, viscosity, and stability through an array of physical, biological, chemical, and alternative methods. Readers will walk away with the knowledge needed to tailor dietary fiber for specific applications in functional food products and precision nutrition for better health outcomes.

  • Genome Editing and Human Health

    • 1st Edition
    • Volume 157
    • English

  • Emerging and Established Therapeutic Targets in Cancer Immunotherapy

    From Bench to Bedside
    • 1st Edition
    • Eyad Elkord + 1 more
    • English
    Emerging and Established Therapeutic Targets in Cancer Immunotherapy: From Bench to Bedside provides a comprehensive overview of emerging and established therapeutic targets and strategies in cancer immunotherapy. As cancer immunotherapy continues to evolve, this volume connects fundamental scientific insights with therapeutic development and clinical translation, providing a valuable resource for researchers, clinicians, and students. Chapters examine immune checkpoints, including LAG-3, TIM-3, TIGIT, and VISTA; modulation of the tumor microenvironment through targeting myeloid-derived suppressor cells, regulatory T cells, and stromal components; and emerging approaches such as neoantigen-based vaccines, multispecific antibodies, and next-generation CAR-T cell therapies. Additional chapters address tumor mutational burden, metabolic reprogramming, epigenetic regulation, and the microbiome, alongside strategies to overcome therapeutic resistance and the application of multi-omics and artificial intelligence to target discovery. Regulatory and manufacturing considerations for clinical translation are also discussed. The volume provides current scientific insights, identifies promising research directions, and offers practical guidance for developing effective immunotherapies, helping researchers design innovative experiments and accelerate drug development, and clinicians understand emerging therapies and optimize patient care. It is a vital resource for advancing the next generation of cancer immunotherapy and improving outcomes for patients worldwide.

  • Traumatic Brain Injury Rehabilitation

    • 1st Edition
    • Vishal K. Chavda + 4 more
    • English
    Traumatic Brain Injury Rehabilitation addresses the critical need for an integrated resource spanning traumatic and vascular brain injury models. This reference consolidates diverse experimental platforms from classical rodent systems to advanced human brain organoids and AI-driven simulations, targeting researchers and clinicians navigating the complexities of neurotrauma and stroke. The book responds to the growing demand for translational approaches that link bench-side discoveries with bedside applications to improve therapeutic development. The content is systematically organized into sections covering foundational principles, preclinical models of traumatic brain injury and stroke, pediatric brain injury models, in vitro and ex vivo platforms, clinical biomarkers and neuroimaging, and emerging future directions including personalized medicine and AI modeling. Each chapter offers detailed methodologies, comparative evaluations, and clinical translation insights, supported by extensive visuals such as flowcharts, neuroimaging figures, and infographics to enhance comprehension.

  • Systems Biology of Addiction Medicine

    Gut–Brain Axis, OMICS, and Molecular Technologies
    • 1st Edition
    • Mohammad Shabani + 3 more
    • English
    Systems Biology of Addiction Medicine: Gut–Brain Axis, OMICS, and Molecular Technologies is a cutting-edge reference that explores the complex neurobiological mechanisms underlying substance use disorders (SUD). This volume emphasizes the importance of the microbiome-gut-brain axis (MGBA), multi-OMICS approaches, and molecular tools such as CRISPR-Cas9 in advancing addiction research. It addresses the urgent need for integrated frameworks to understand the bidirectional communication between the gut and brain in disorders like nicotine, opioid, alcohol, neurostimulant, and cannabis use. The book synthesizes foundational knowledge with recent developments, offering detailed methodologies, case studies, and translational strategies that bridge basic science and clinical application. Its comprehensive scope makes it invaluable for researchers and clinicians seeking to develop personalized, evidence-based therapies for SUDs. The contents include dedicated sections on the MGBA's role across various substances, detailed chapters on multi-OMICS, SNP, and immunotherapy techniques, and discussions on emerging molecular technologies like CRISPR. Each chapter combines literature reviews, recent advances, and practical applications, supported by schematic figures designed for clarity. The volume aims to empower neuroscientists, psychiatrists, pharmacologists, and biotech professionals with the latest scientific insights and tools to address the global challenge of addiction. By fostering interdisciplinary understanding, this resource supports hypothesis generation, research innovation, and the development of targeted interventions to improve patient outcomes.

  • The Biomechanics of Osseointegration

    • 1st Edition
    • Adriano Piattelli + 1 more
    • English
    The Biomechanics of Osseointegration offers a comprehensive, evidence-based exploration of the biomechanical, anatomical, and biological principles essential to safe and effective use of dental implants. By integrating core sciences with clinical applications, it equips both current and future practitioners with the tools to deliver long-term success in implant therapy. From fundamental concepts such as bone biology and stress-strain relationships to advanced topics like finite element modeling, fatigue testing, and real-world clinical implications, this work bridges the divide between theory and practice. Readers gain deep insight into the biomechanics of standard, short, pterygoid, and zygomatic implants across varying bone types, loading conditions, and anatomical challenges. Examined are long-term histological findings from retrieved human implants, unpacking the reasons behind the success of design elements such as the Cone Morse connection. Grounded in both research and practical examples—including case studies and data spanning three decades—the importance of connecting basic science with clinical expertise is highlighted. Designed primarily for dentists considering the integration of implantology into their practice, as well as postgraduate students in Periodontology, Prosthodontics, Oral Surgery, and Biomedical Engineering, The Biomechanics of Osseointegration also serves as a valuable resource for undergraduate dental and biomechanical engineering students who are entering the field with limited formal education in implant science. With an interdisciplinary approach and emphasis on biomechanics and biology, it provides a critical foundation for anyone committed to advancing in the field of dental implants—ensuring their work is not only innovative but also grounded in safe and effective treatment principles.

  • Substance Use Disorders and Behavioral Addictions

    Neurochemical Mechanisms and Clinical Implications
    • 1st Edition
    • Mohammad Shabani + 2 more
    • English
    Substance Use Disorders and Behavioral Addictions: Neurochemical Mechanisms and Clinical Implications offers an in-depth exploration of the neurochemical foundations of addiction, addressing both substance-related and behavioral disorders. This volume is essential for neuroscientists, psychiatrists, and pharmacologists seeking to understand the complex neurobiological pathways involved in addiction. It covers key neurochemical systems such as dopamine, glutamate, serotonin, and endocannabinoids, and examines their roles across a spectrum of disorders including nicotine, opioids, alcohol, stimulants, cannabis, psychedelics, sedatives, caffeine, antihistamines, and behavioral addictions like gambling, gaming, pornography, and binge eating. This content synthesizes cutting-edge preclinical techniques—such as optogenetics and neuroimaging—with clinical models like cue-reactivity and pharmacogenomics, providing a translational perspective that bridges research and practice. The purpose of this book is to fill existing gaps where neurochemical insights are often isolated from clinical application, especially in the context of rising addiction rates globally and emerging treatments like psilocybin and neuromodulation. It aims to equip researchers and clinicians with current, practical knowledge to develop innovative interventions, improve diagnostics, and personalize treatment strategies. Whether used as a reference for research, clinical decision-making, or advanced coursework, this volume offers a vital resource for advancing understanding and management of addiction in diverse settings.

  • Smart Microscopy, AI, and Robotics

    Automated Future Disease Detection
    • 1st Edition
    • Priyadarshini Pattanaik + 2 more
    • English
    Smart Microscopy, AI, and Robotics: Automated Future Disease Detection addresses the need to combine automated microscopy with artificial intelligence and robotics to improve accuracy, throughput, and safety in disease detection. It surveys methods for image acquisition, processing, segmentation, and interpretation across sample types, including blood smears, tissue biopsies, cytology, and cytopathology, equipping researchers, clinicians, and technologists with actionable knowledge for deploying AI-powered diagnostic pipelines.The book covers foundational principles and advanced applications, beginning with microscopy and contrast-enhanced imaging, followed by automated microscope–robotics integration, image acquisition and analysis pipelines, and AI methods for disease detection. It then explores applications such as blood disorders, infectious diseases, and cancer diagnostics, including AI-based analysis of neurological and cellular imaging, advanced deep-learning architectures, and foundation models for smart microscopy. System-level considerations address performance metrics, explainability, bias mitigation, ethics, clinical governance, regulation, safety, and human–AI interaction and interoperability. The book also examines AI-enabled drug discovery, therapeutic target identification, smart laboratories, automated diagnostics, and global health impact.Readers will gain practical guidance on building high-throughput, AI-assisted diagnostic systems that are robust, interpretable, and scalable, with insights into data annotation, model validation, and integrating AI with robotic microscopy in clinical and research settings. The work anticipates developments such as self-calibrating instruments, autonomous laboratory workflows, and digital pathology ecosystems.

  • Redefining the MicroRNA Functionality in Cancer Diagnostics and Therapeutics

    • 1st Edition
    • Vivek Kumar + 2 more
    • English
    Redefining the MicroRNA Functionality in Cancer Diagnostics and Therapeutics is an authoritative volume that explores the pivotal role of microRNAs (miRNAs) in precision oncology. The book integrates fundamental biology, cutting-edge bioinformatics, and translational research, providing a comprehensive overview of miRNA mechanisms, regulation, and clinical applications. It emphasizes technological advances such as single-cell profiling, CRISPR engineering, and AI-driven diagnostics. The content covers miRNA biology, multi-omics integration, innovative therapeutic strategies, and clinical translation, including liquid biopsies and biosensors.In addition, it also addresses industry and regulatory aspects, offering practical insights for translating research into clinical and commercial settings. Rich with case studies and visual aids, the book bridges the gap between bench research and bedside implementation. For the academic audience, this book offers a multidisciplinary resource that enhances understanding of miRNA-based diagnostics and therapeutics, fostering innovation and accelerating clinical adoption in cancer care.

  • Advances in Immunology

    • 1st Edition
    • Volume 172
    • English
    Advances in Immunology, Volume 172, provides current research contributions in immunology, including a detailed examination of gasdermin activation mechanisms and their role in initiating membrane pore formation to execute pyroptosis. Further chapters from an international group of contributors extend the volume's coverage of immune mechanisms and disease relevance.

  • Epigenetics of Alzheimer's and Parkinson's Disease Part A

    • 1st Edition
    • Volume 118
    • English
    Epigenetics of Alzheimer's and Parkinson's Disease Part A, published as Volume 118 of the serial Advances in Genetics, provides a focused survey of the epigenetic mechanisms underlying two of the most prevalent neurodegenerative disorders. Contributions from international researchers examine microRNA-based therapeutic strategies, exosome-mediated pathways, noncoding RNA regulation, DNA and histone modifications, and gene-environment-epi... interactions in Alzheimer's and Parkinson's disease. The volume offers researchers a current reference point for understanding how epigenetic regulation contributes to disease onset and progression, and how these mechanisms might be targeted therapeutically.

  • Microbiome-Drug Interactions in Neurological Disorders: Pharmacological Mechanisms, Targets, and Therapeutic Advances

    • 1st Edition
    • Volume 109
    • English
    Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Contemporary Practice in Clinical Chemistry

    • 5th Edition
    • William Clarke + 1 more
    • English
    Contemporary Practice in Clinical Chemistry, Fifth Edition is a comprehensive, updated reference and teaching resource focused on Laboratory Medicine, specifically tailored for clinical chemistry faculty, trainees, clinical laboratory scientists, clinical pathologists, and laboratory managers. Edited by renowned experts, the book integrates cutting-edge developments in clinical chemistry with practical applications for professional practice. This new edition covers foundational and advanced topics in clinical chemistry and laboratory medicine, emphasizing the integration of new technologies and methodologies. It addresses precision medicine, medical biotechnology, and artificial intelligence applications within the clinical laboratory setting. The content is designed to support both learning and board exam preparation, providing a deep understanding of the field alongside practical insights.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 138
    • English

  • Viticulture and Climate Change

    Challenges and Opportunities
    • 1st Edition
    • Stefano Poni
    • English
    Accelerating atmospheric shifts are redefining grape production worldwide in complex and often unpredictable ways, disrupting long-established practices while opening the door to new possibilities. Viticulture and Climate Change examines how rising temperatures, irregular rainfall patterns, and increasingly frequent extreme events influence cultivation outcomes, including vine seasonal development, berry composition, and overall vineyard performance. It presents a forward-looking panorama that translates scientific insight into applied guidance, enabling the effective implementation of adaptive and sustainable grape-growing practices.Rather than treating individual factors in isolation, the text adopts a whole-system view. The volume is organized to follow the vineyard lifecycle, from establishment through routine operations to long-term planning, with case studies aptly embedded throughout. It addresses variety and rootstock selection, spacing, training systems, soil care, canopy handling, water use, and innovative inputs. Dedicated sections explore frost, heatwaves, drought, flooding, and hail scenarios, alongside appropriate responses such as pruning adjustments, shading solutions, and protective materials. Emerging topics—such as manipulation of ripening dynamics for low- and no-alcohol wines, carbon cycling, and renewable energy integration—are also considered.Advances in sensing, mapping, automation, and modeling are presented within interconnected digital platforms, offering new ways to monitor conditions and guide interventions. Biotic threats from pathogens and insects are discussed in the context of variable climatic pressures, with emphasis on tolerance and robustness-enhancing measures.Drawing on a broad body of research and experience by a leading expert in the field, Viticulture and Climate Change interprets findings with clarity and purpose, transforming technical information into accessible knowledge with practical relevance across diverse regions in support of improved real-world, cost-effective decision-making.

  • Human-AI Interaction for Digital Healthcare Systems

    • 1st Edition
    • Jinwoo Kim
    • English
    Human-AI Interaction for Digital Healthcare Systems defines Human‑AI Interaction (HAII) as the next evolutionary phase of Human‑Computer Interaction, addressing the shift from reactive systems to proactive AI agents. Using digital healthcare as its primary application domain, it introduces a rigorous, evidence‑based methodology for designing AI systems that are effective, safe, and trusted in real‑world clinical contexts. The text integrates the Sensing–Reasoning–Ac... (SRA) loop into human‑centered design, balancing system efficacy with environmental conformance. It provides structured guidance across the full lifecycle, analysis, planning, design, and evaluation,ensuring AI systems deliver measurable clinical and user value. Beyond theory, the book emphasizes empirical validation, detailing controlled experiments (e.g., RCTs) and real‑world performance analysis using Real‑World Data (RWD) and Real‑World Evidence (RWE), with explicit consideration of regulatory requirements for Software as a Medical Device (SaMD).

  • Mitochondria Part A

    • 1st Edition
    • Volume 216
    • English

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