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Books in Life sciences

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  • Bioactive Polyphenols for Health and Pathology Treatment

    • 1st Edition
    • Antonio Segura Carretero + 2 more
    • English
    Bioactive Polyphenols for Health and Pathology Treatment presents the most up-to-date research on the role of polyphenols in physiological function, organs, and disease. Presenting preclinical animal studies and clinical assays from different points of view, this book explores how herb extracts affect cardiovascular, cognitive, and immunological health and their action on obesity, cancer, digestion, blood pressure, diabetes, mood, and on the skin and eyes. This book begins with the biological properties and pathways of polyphenols, their bioavailability, phytochemistry, and, finally, their pharmacological action. This book closes exploring the processing and production of polyphenols within functional foods and as nutraceuticals.This book is an excellent resource for professionals and academics working in the phytochemical and medical fields, including food chemists, nutritionists, and industrialists, as well as postgraduate students.

  • Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis

    • 1st Edition
    • Volume 211
    • English
    Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis, Volume 112 delves into the fascinating interplay between osmolytes and intrinsically disordered proteins (IDPs), exploring their pivotal roles in cellular function and disease mechanisms. This volume brings together experts to present cutting-edge research on how osmolytes regulate functional behavior of IDPs and ensure cellular stability and adaptability under stress conditions. Specific chapters cover Functional diversity of IDPs and their structural heterogeneity: Protein structure-function continuum, Osmolytes as structure-function regulators of intrinsically disordered casein, Synergism of the effects of osmolytes and crowders on structure and function of IDPs/IDRs: The natural habitat, and more.Additional chapters delve into Osmolyte-IDP Interactions during Desiccation, Modulation of aggregation/fibrilla... propensity of IDPs by osmolytes, Osmolytes in modulating the structural and functional integrity of α-synuclein: a study based on Parkinson's disease, Regulation of the structural dynamics, aggregation, and pathogenicity of polyQ-expanded Huntingtin by osmolytes, Aggregation and inhibitory strategies of amyloid fibrillation, and much more.

  • Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

    • 2nd Edition
    • Mahendra Rai
    • English
    Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components, Second Edition offers pharmaceutical and life sciences researchers an overview on the most relevant studies for fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses, and fungi using natural products. This new edition expands the coverage of uses of traditional medicinal plants to against MDR, includes new chapters on the potential of plant-derived bioactive compounds for reversal of multidrug resistances, covers the use of flavonoids to combat microbes and cancer, and the use of nanoparticles as drug delivery vehicle.The need to combat multidrug-resistant microorganisms is an urgent one. This book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components, and more, to aid researchers in effective antimicrobial drug discovery.

  • Organic Mechanochemistry

    A New Tool for Sustainable Synthesis
    • 1st Edition
    • Davor Margetic
    • English
    Organic Mechanochemistry: A New Tool for Sustainable Synthesis presents the greener chemical method to a broader reading audience, including chemical practitioners. Descriptions of each method, followed by examples on sustainability aspects and applications give readers a better understanding and realization of its possibilities. Mechanochemistry, a nonconventional method for inducing the chemical reaction by application of mechanical energy in solid state, has been recognized as beneficial as mechanochemically conducted reactions hold diverse environmental sustainability advantages in manufacturing processes.

  • Navigating Endophytic Research for Next-Generation Therapeutics

    • 1st Edition
    • Vagish Dwibedi + 3 more
    • English
    Navigating Endophytic Research for Next-Generation Therapeutics explores the evolving field of endophytic fungal research and applications in combating diseases, addressing environmental challenges, and in shaping the future of therapeutics. The book starts off with a discussion on the biodiversity and biogeography of endophytic fungal communities and describes the bioprospecting of endophytes for drug discovery. In addition, it covers the therapeutic application of endophytic fungi to treat and manage specific diseases and investigates the innovative use of technologies such as genome editing, genetic engineering for enhanced bioactivity, multi-omics-based exploration, and the use of big data and machine learning in endophytic drug discovery.Featuring contributions from experts across fields like mycology, pharmacology, biotechnology, and environment science, this comprehensive, practical, and insightful resource guides those engaged in endophytic fungal research and its transformative potential in next-generation therapeutics.

  • Colorectal Imaging

    From Basic to Advanced Concepts
    • 1st Edition
    • Luca Saba
    • English
    Colorectal Imaging: From Basic to Advanced Concepts provides an exhaustive overview of today’s basic and advanced principles of colorectal imaging, focusing not only on oncologic but also inflammatory, infective, and ischemic pathologies and complications. The book reviews basic colorectal cancer information, examines imaging techniques and analysis, and concludes with a review of non-neoplastic pathologies. It is a useful resource for scientists, physicians, and medical students in the discipline of radiology, highlighting the critical role of contemporary imaging in guiding clinical and surgical approaches and providing the knowledge needed to confidently choose the most appropriate imaging examination.

  • Plant Functional Traits

    Linking Climate and Ecosystem Functioning
    • 1st Edition
    • Manoj Kumar + 2 more
    • English
    Plant Function Traits: Linking Climate and Ecosystem Functioning, part of the Plant Biology, Sustainability and Climate Change series, presents a wholistic understanding of Plant Functional Traits. As global climate change advances, natural resources are facing increasing survival challenges, hence this book directly addresses that need, exploring the morphological, physiological, and phenological properties of a plant that can be used as a proxy to understand plant environment interactions. Users will find great illustrations throughout individual chapters, along with case studies that demonstrate applications of functional traits in classifying vegetation of a region into distinct type groups as Plant Functional Types (PFTs).Additional information includes applications in the development of new generation of Dynamic Global Vegetation Model (DGVM) and an understanding of the response of vegetation to changing environments.

  • Applications of Nanotherapeutics and Nanotheranostics in Managing Infectious Diseases

    • 1st Edition
    • Anoop Kumar + 1 more
    • English
    Applications of Nanotherapeutics and Nanotheranostics in Managing Infectious Diseases discusses how nanotechnology aids in overcoming the existing traditional approaches in combating diseases. The book explores the emerging trends of using nanoparticles for nanotherapeutics and nanotheranostics and their role in the efficient diagnosis and treatment of infectious microbial diseases. Sections covers nanotherapeutic impregnated medical devices, nanotherapeutics as vaccines, related regulatory requirements, the application of nanotherapeutics and nanotheranostics in diagnosing and treating specific infectious diseases, including bacterial infections, viral infections, fungal infestations, parasitic infestations, and other infectious conditions.With chapter contributions from experts in the fields, this book offers a comprehensive reference for researchers, scientists, and industry professionals working on infectious diseases and the application of nanoparticles to effectively diagnose, treat, and manage them.

  • Biofarmacia y farmacocinética

    • 3rd Edition
    • Antonio Aguilar Ros + 3 more
    • Spanish
    Esta nueva edición actualiza plenamente contenidos y conceptos, abordando los principales modelos de cálculo de la Biofarmacia y Farmacocinética a través de la resolución de problemas, todo ello en un estilo riguroso y con una perspectiva eminentemente práctica. Incorpora nuevos capítulos sobre ajuste posológico en insuficiencia renal, y sobre modelos farmacocinéticos/far... (PK/PD), así como un capítulo final consistente en 50 cuestiones tipo test para estudio y repaso. Para esta edición se han incorporado además nuevos autores.Los capítulos comienzan con un breve repaso del esquema del modelo y de las ecuaciones que posteriormente se utilizan en los problemas, que se resuelven paso a paso a continuación. La obra está dirigida tanto a los estudiantes de la materia como a los profesionales de distintos ámbitos que deseen profundizar y ampliar sus conocimientos en Biofarmacia y Farmacocinética. Se ofrece acceso a la versión electrónica completa del libro a través de la plataforma VitalSource. Esta versión incluye los siguientes contenidos complementarios: Problemas extra por capítulo, con sus soluciones; Enlaces a archivos para la impresión de papel milimetrado y semilogarítmico para la elaboración de gráficas, Enlaces a archivos Excel (con complemento SOLVER) para el cálculo y elaboración de gráficas, mediante regresión no lineal de los distintos modelos de biofarmacia y farmacocinética que se desarrollan en el libro.

  • The Auditory Cerebellum

    Function and Dysfunction
    • 1st Edition
    • Jos J. Eggermont
    • English
    The Auditory Cerebellum: Function and Dysfunction focuses on the sensory and cognitive aspects of the cerebellum, with an emphasis on hearing, speech, music, speaking, and singing. This book fills the gap for information needed in audiology and auditory neuroscience, tinnitus, and developmental disorders with a strong auditory component. This book starts with a general overview on the connectivity between the cerebellum and auditory subcortical and cortical areas, including general cortical networks. There are several chapters devoted to the timing aspects of the cerebellum underlying speech and music perception as well as motor aspects in speaking and singing.Also discussed is the role of the cerebellum in hearing impairment, tinnitus, developmental disorders with a strong auditory component, including dyslexia, autism, attention deficit, and hyperactivity disorder. Dr. Jos Eggermont, a leading researcher in the field, uses a systems analysis approach that covers electrophysiology and neural imaging, both in animals and humans.

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