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    • Biofarmacia y farmacocinética

      • 3rd Edition
      • Antonio Aguilar Ros + 3 more
      • Spanish
      Esta nueva edición actualiza plenamente contenidos y conceptos, abordando los principales modelos de cálculo de la Biofarmacia y Farmacocinética a través de la resolución de problemas, todo ello en un estilo riguroso y con una perspectiva eminentemente práctica. Incorpora nuevos capítulos sobre ajuste posológico en insuficiencia renal, y sobre modelos farmacocinéticos/far... (PK/PD), así como un capítulo final consistente en 50 cuestiones tipo test para estudio y repaso. Para esta edición se han incorporado además nuevos autores.Los capítulos comienzan con un breve repaso del esquema del modelo y de las ecuaciones que posteriormente se utilizan en los problemas, que se resuelven paso a paso a continuación. La obra está dirigida tanto a los estudiantes de la materia como a los profesionales de distintos ámbitos que deseen profundizar y ampliar sus conocimientos en Biofarmacia y Farmacocinética. Se ofrece acceso a la versión electrónica completa del libro a través de la plataforma VitalSource. Esta versión incluye los siguientes contenidos complementarios: Problemas extra por capítulo, con sus soluciones; Enlaces a archivos para la impresión de papel milimetrado y semilogarítmico para la elaboración de gráficas, Enlaces a archivos Excel (con complemento SOLVER) para el cálculo y elaboración de gráficas, mediante regresión no lineal de los distintos modelos de biofarmacia y farmacocinética que se desarrollan en el libro.

    • The Auditory Cerebellum

      Function and Dysfunction
      • 1st Edition
      • Jos J. Eggermont
      • English
      The Auditory Cerebellum: Function and Dysfunction focuses on the sensory and cognitive aspects of the cerebellum, with an emphasis on hearing, speech, music, speaking, and singing. This book fills the gap for information needed in audiology and auditory neuroscience, tinnitus, and developmental disorders with a strong auditory component. This book starts with a general overview on the connectivity between the cerebellum and auditory subcortical and cortical areas, including general cortical networks. There are several chapters devoted to the timing aspects of the cerebellum underlying speech and music perception as well as motor aspects in speaking and singing.Also discussed is the role of the cerebellum in hearing impairment, tinnitus, developmental disorders with a strong auditory component, including dyslexia, autism, attention deficit, and hyperactivity disorder. Dr. Jos Eggermont, a leading researcher in the field, uses a systems analysis approach that covers electrophysiology and neural imaging, both in animals and humans.

    • Haschek and Rousseaux's Handbook of Toxicologic Pathology Volume 5: Toxicologic Pathology of Organ Systems

      • 4th Edition
      • Wanda M Haschek + 3 more
      • English
      Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, Volume Five: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals, and biologics. This book continues coverage of Organ-Specific Toxicologic Pathology and major organ systems not covered in Volume Four, and has been completely revised, making it an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants.

    • Patterns, Function and Application of Seed Microbiome

      Bacteria, Fungi and Viruses
      • 1st Edition
      • Mohammad Yaseen Mir + 3 more
      • English
      Patterns, Function and Application of Seed Microbiome: Bacteria, Fungi and Viruses presents the current understanding of seed and microbiota associations, emphasizing recent findings that highlight the latest insights into these interactions, and how they may ultimately influence plant ecology, health and productivity in both natural and agricultural systems. The development and dispersal of seeds and their transition to seedlings are among the most critical stages of the life cycle of plants and seed health is of crucial global importance for producing both quantity and high quality crops to feed world’s population. It is important for seeds to be produced that contain the best hybrid embryo so that it is free of diseases, includes beneficial endophytes and ensures a healthy start of a seedling. Focusing on the role of seed microbiota, their transmission and implications for producing healthier seeds as well as the relationship between the seed microbiome and primed plant resistance this book reveals the targeted use of the seed microbiome to enrich the soil biodiversity and its resilience and its resulting impact on plant health and yield. also explores the importance of nanotechnology in the development and production of crops for both improved plant production, and plant protection. It explores the different microbes that are vectored onto and within the seeds of both cultivated and non-cultivated plants, with an emphasis on the importance and roles of seed microbiomes in sustainable agriculture. It explains how to change seeds to increase microbiome vectoring; repairing damaged ones, and conserves seed microbiota. It also present seed microbiome roles for plant health and design effective microbiome engineering.

    • Biochar Ecotechnology for Sustainable Agriculture and Environment

      • 1st Edition
      • Abhay Kumar + 3 more
      • English
      Biochar Ecotechnology for Sustainable Agriculture and Environment summarizes current accomplishments in biochar ecotechnologies for enhancing agricultural production, encouraging sustainable waste management, and fostering a circular bioeconomy by advancing the pyrolysis process at both large-scale industrial and small-scale-local levels. Chapters in the book synthesize recent breakthroughs in biochar agro-ecotechnologies for increasing agricultural productivity and promoting circular bioeconomy by advancing the pyrolysis process and add mechanisms involved in biochar-fertilizer mediated in-soil biogeochemical cycle and nutrients retention, availability and their losses, soil-microbial responses, emission of greenhouse gases, and plant responses.Finally, this book aims to increase research understanding of nanotechnological breakthroughs in the production of biochar-based slow-release fertilizers, including their Nano characteristics involved in increasing fertilizer usage efficiency and managing chemical losses, for sustainable agriculture and the environment.

    • Medicinal Chemistry and Drug Development

      • 1st Edition
      • Gang Liu
      • English
      Medicinal Chemistry and Drug Development describes the key events and roles of medicinal chemistry in the discovery and development of lead compounds into drugs, including target identification, which is accomplished by using 30 case studies. This book outlines all the stages of drug development, including the discovery of active compounds, research on the pharmacologicalprope... of molecules, and confirmation of drug targets. The role of the case studies is to show the common factors in the successful development of drugs, thereby showing medicinal chemists how best to explore the scientific pathways when developing new drugs. This makes the book especially relevant for senior university students majoring in pharmaceutical sciences as well as graduate students and researchers.

    • Targeting Enzymes in the Brain

      • 1st Edition
      • Volume 102
      • English
      Targeting Enzymes in the Brain series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

    • Handbook of Immunoassay Technologies

      Approaches, Performances, and Applications
      • 2nd Edition
      • Sandeep K. Vashist + 1 more
      • English
      Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats. The book discusses how advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies that have paved the way for next-generation immunoassays.Revised and updated, the second edition of Handbook of Immunoassay Technologies: Approaches, Performances, and Applications covers all the relevant, timely, and important developments in the field. This edition offers new content on topics such as antibody production for immunodiagnostics, multiplex immunoassays, chemiluminescent immunoassays, immunoassays for newborn screening, and immunoassays of viruses like SARS-CoV-2, HIV, Ebola, and Hepatitis C. The addition of these new topics as well as up-to-date content make the second edition a valuable and comprehensive resource on immunoassays.

    • The Immunological Synapse Part C

      • 1st Edition
      • Volume 193
      • English
      The Immunological Synapse - Part C, Volume 193 in the Methods in Cell Biology series provides state-of-the-art and detailed methods for the study of the T cell, natural killer (NK) cell and B cell immunological synapses. Topics covered in this third volume include tau-STED microscopy for 3D-quantitative colocalization of lytic granule markers, image processing approaches for 3D-analysis of markers and for microtubule remodeling quantification at the immunological synapse, flow cytometry to analyze NK cell-target cell conjugation, imaging flow cytometry to quantify a range of different subcellular processes at the immunological synapse, imaging techniques aimed at quantitatively analyzing B cell immunological synapse formation, quantification of force-mediated antigen extraction in the B cell immune synapse using DNA-based tension sensors, measuring interaction forces between T lymphocytes and their target cells using live microscopy and laminar shear flow chambers, measuring interaction kinetics between T cells and their target tumor cells with optical tweezers, and gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice. Additionally, this volume includes methods to isolate and characterize primary NK cells and enrich the KIR2DL1+ population, and to expand γδ T cells and evaluate their cytotoxicity.

    • Commercial Pig Farming

      A Guide for Swine Production and Management
      • 1st Edition
      • Anuj Chauhan + 5 more
      • English
      Commercial Pig Farming: A Guide for Swine Production and Management provides a comprehensive overview of the pig farming sector, which accounts for approximately 35% of meat production globally. Written by authors spanning 25 chapters, this book aims to provide broad coverage on the key aspects of commercial pig farm management including breeding and reproduction, housing, mechanization, feeding, health and welfare, pork processing, marketing, waste management, and circular bioeconomy. The book will move beyond the basics to cover state-of-the art and cutting-edge technologies in the industry, from artificial intelligence tools and smart phone applications for swine health and feeding management, to the latest vaccinations strategies and biosecurity guidelines for pigs.The most complete and current guide to pig farming available on the market, this book will be most useful to progressive farmers, researchers, and graduate and post-graduate students interested in veterinary science, animal agriculture, and meat production and processing. Professionals working in the pig industry and other livestock industry stakeholders will also find this a valuable resource.

Related subjects

Agricultural and biological sciences

Drug discovery

Immunology

Microbiology and virology

Neuroscience

Pharmaceutical sciences

Pharmacology

Toxicology