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Elsevier

Books in Life sciences

  • Federated Intelligence in Medicine

    AI-Driven Robotics for Secure and Intelligent Healthcare Systems
    • 1st Edition
    • Manisha Guduri + 3 more
    • English
    Federated Intelligence in Medicine: AI-Driven Robotics for Secure and Intelligent Healthcare Systems explores the rapidly evolving field where medical robotics intersects with cutting-edge artificial intelligence and secure data-sharing technologies. Covering a comprehensive range of topics, the book begins with foundational knowledge in medical robotics and Generative AI, progressing to advanced concepts such as federated learning and architectural modeling tailored for AI-driven robotic systems. Readers will explore algorithms enhancing surgical robotics, remote robotic surgeries, and human-robot interaction. The text also tackles AI-driven diagnostic robots, privacy preservation through homomorphic encryption, and differential privacy and emerging medical imaging techniques integrated with robotics.Later chapters examine the synergy of large language models, agent AI, and edge AI with robotic technologies, providing both theoretical frameworks and practical case studies that illuminate real-world applications and challenges. This book is an invaluable resource for researchers and academicians engaged in artificial intelligence, robotics, and medical technology. It also serves undergraduate and graduate students in Biomedical Engineering, Electronics and Electrical Engineering, and Computer Science and Engineering.

  • Gender Affirming Hormone Therapy in Humans

    Evidence from Murine Models
    • 1st Edition
    • Jeffrey David Zajac
    • English
    Gender Affirming Hormone Therapy in Humans: Evidence from Murine Models is an unprecedented reference for scientists, researchers, students and anyone interested in this field of research. The book is a review of the current state of mouse animal models of relevance to transgender health. It's divided into chapters specific for different tissues in which mouse models are described and their relevance to human health is discussed. This is a novel reference summarizing what these models demonstrate about the benefits and risks of GAHT and the most effective and lowest risk approach to treatment. The models suggest applications of this research to human studies and treatment of transgender people. There is an expanding number of transgender people with are few evidence based books that address this field relating to the importance and growing role of murine models.

  • Clinical Management of Pancreatic Cancer

    From Diagnosis to Palliative Care
    • 1st Edition
    • Takuji Okusaka + 1 more
    • English
    Clinical Management of Pancreatic Cancer: From Diagnosis to Palliative Care provides comprehensive guidance and support at every step of the pancreatic cancer journey, covering initial diagnosis and compassionate and holistic care. The book not only presents the latest advancements, including innovative surgical techniques, targeted therapies, radiotherapy approaches, and palliative care interventions, but also focuses on maintaining and improving patients' quality of life throughout their journey and incorporating palliative medicine and supportive care to alleviate symptoms and enhance overall well-being. Sections advocate for patient-centered care by emphasizing communication, shared decision-making, and tailored treatment approaches to individual needs and preferences.In addition, the book raises awareness about pancreatic cancer, its challenges, and the importance of early detection while also dispelling misconceptions and offering hope through informed management strategies. It serves as a bridge between research and clinical practice, offering researchers a broader perspective while also equipping clinicians with a valuable resource that enhances their knowledge, decision-making, and patient care skills.

  • Deciphering Cancer Resistance

    Mechanisms, Targets, and Emerging Therapies
    • 1st Edition
    • Abraham Pedroza + 1 more
    • English
    Deciphering Cancer Resistance: Mechanisms, Targets, and Emerging Therapies addresses the critical challenge of treatment resistance in oncology. The book provides a comprehensive examination of the cellular, molecular, and genetic mechanisms behind resistance, unveiling insights from cancer biology and genomics that inform novel therapeutic strategies. Sections explore cutting-edge technologies like CAR-T cell therapy, nanotechnology, and artificial intelligence, highlighting their role in discovering new treatment modalities. Readers will find the latest preclinical and clinical data, including newly FDA-approved therapies, demonstrating their potential to improve patient outcomes.For academics, this resource consolidates the latest research and clinical developments, aiding researchers, clinicians, and students in staying updated on advancements. It will also be a great guide for graduate studies and research, offering critical insights into drug development and targeted therapies for professionals in the pharmaceutical and biotechnology sectors, ultimately driving progress in cancer treatment.

  • Twin-to-Twin Transfusion Syndrome (TTTS)

    • 1st Edition
    • Michael W. Bebbington + 1 more
    • English
    Twin-to-Twin Transfusion Syndrome (TTTS) is a novel and comprehensive reference to understanding the pathophysiology of this condition, along with the latest diagnostic techniques and criteria for accurate identification, its treatment and management, and strategies for effective management and care. Beyond medical aspects, the book addresses the emotional and practical aspects of TTTS, offering guidance on patient/family support and coping strategies. It includes the latest guidelines and evidence-based practices for TTTS, helping clinicians stay current with advancements in the field and ensuring they adhere to the best standards of care.In addition, the book offers real-world case studies and practical guidance to enable clinicians to effectively apply their knowledge in clinical settings, enhancing their ability to diagnose and manage TTTS cases. Written by various experts in the field, this multidisciplinary perspective fosters collaboration and enables anyone involved in this field to make informed decisions in complex TTTS cases.

  • Human-Centred AI For Intelligent Healthcare

    Approaches and Technologies
    • 1st Edition
    • Mahmoud Hassaballah + 1 more
    • English
    Human-Centred AI For Intelligent Healthcare: Approaches and Technologies provides state-of-the-art AI technologies and healthcare tailored to human needs, highlighting the various ways AI is reshaping patient care, diagnostics, treatment modalities, and overall healthcare systems. From the intricacies of precision medicine to interventions in mental health, this reference provides a diverse array of AI applications. It addresses ethical considerations while emphasizing the transformative potential that AI holds for the healthcare industry. This reference is an essential companion for healthcare professionals, researchers, policymakers, technologists, and enthusiasts navigating the swiftly evolving landscape of AI in healthcare. Bridging a critical gap in literature, it offers a consolidated resource that not only explores the multifaceted applications of AI in healthcare but also underscores the importance of maintaining a human-centric approach in the integration of these technologies. With a focus on forecasting future trends and implications, this reference equips readers with the knowledge to stay at the forefront of the dynamic field of healthcare technology and empowers them to anticipate changes and adapt their strategies proactively in the face of evolving healthcare landscapes.

  • Nanomaterials for Stem Cell Modulation

    Innovation and Clinical Applications
    • 1st Edition
    • Syed Mahmood + 3 more
    • English
    Nanomaterials for Stem Cell Modulation: Innovation and Clinical Applications provides a comprehensive exploration of how nanotechnology is transforming stem cell science and regenerative medicine. This authoritative volume examines the physicochemical properties of nanomaterials, their interactions with stem cells, and their capacity to direct stem cell behaviors such as proliferation, differentiation, and therapeutic delivery. By blending foundational principles with cutting-edge innovations, the book bridges the gap between basic laboratory discoveries and clinical translation. Written by experts in the field, the book addresses the critical need for an integrated resource that unifies current knowledge with emerging research and practical applications.While interest in nanotechnology and stem cells continues to grow, the literature remains fragmented. This book fills that gap by offering structured insights, case studies, and guidance on selecting nanomaterial systems tailored to specific therapeutic goals, while also navigating regulatory and translational challenges. Designed for researchers, graduate students, and professionals, the text serves as both a practical guide and an academic reference across disciplines including nanotechnology, stem cell biology, regenerative medicine, tissue engineering, biomedical engineering, and pharmaceutical sciences.

  • Algorithmic Approaches for the Diagnosis of Common Neurological Emergencies

    • 1st Edition
    • Gentle Sunder Shrestha + 3 more
    • English
    Algorithmic Approaches for the Diagnosis of Common Neurological Emergencies is a practical resource aimed at clinicians working in the field of neurology. By providing an algorithmic approach to diagnosing patients, this volume helps clinicians quickly and systematically approach patients, minimizing the risk of missing common neurological emergencies. Offering case studies and various common neurological scenarios, readers will be able to pick up on warning signs of serious neurological emergencies and treat patients effectively. Users will find this to be a valuable guide to help manage patients with neurological emergencies with limited resources.

  • The Fundamentals of Digital Oncology

    • 1st Edition
    • Luca Maria Gambardella + 1 more
    • English
    The Fundamentals of Digital Oncology is an essential introduction to the rapidly developing landscape of digital technologies in cancer care. This first volume lays the groundwork for understanding the pivotal role of big data, artificial intelligence, and interdisciplinary collaboration in shaping modern oncology. With a clear and structured overview, the book welcomes newcomers by breaking down complex concepts and guiding readers through the latest advancements, challenges, and practical applications. By reflecting cutting-edge research, it equips readers to appreciate the transformative impact of digital tools, from research labs to patient bedsides, and highlights the necessity of teamwork in driving progress.In addition, the book delves into critical topics such as virtual tumor boards, ethical considerations in AI, and strategies for integrating digital approaches into clinical decision-making. Written for researchers, clinicians, and graduate students, it bridges information gaps by offering actionable insights and real-world examples.

  • Organic Semiconducting Systems for Applications in Biomedical Engineering

    • 1st Edition
    • Neha Rani Kumar + 1 more
    • English
    Organic Semiconducting Systems for Applications in Biomedical Engineering explores the properties and applications of organic semiconductors, which are conjugated systems made from small organic molecules or polymers that exhibit semiconductor characteristics. These materials offer flexibility, lightweight construction, low cost, and large-area production capabilities. Their tunable electronic and optical properties, along with biocompatibility, such as biosensors, smart drug delivery systems, medical diagnostics, and implantable devices.The book targets professionals and students in the fields of organic electronics, biomedical engineering, biomaterials, and environmental science. It provides a comprehensive understanding of organic conjugated systems and their principles, aiding readers in designing innovative solutions for challenges in medical sectors. Additionally, it delves into the latest research findings and practical applications of organic semiconductors, helping readers stay informed and identify new research opportunities. This book clarifies complex concepts, making it suitable for beginners. It also offers a forward-looking perspective on the potential of organic semiconductors to revolutionize biotechnology, inspiring readers to pursue research and innovation for sustainable development.Overall, this book serves as an essential resource for understanding organic semiconductors in biotechnology, biomedical engineering, and bioelectronic applications.

  • Omics Approaches in Rhizosphere Microbiology: Part A

    • 1st Edition
    • Volume 60
    • English
    Omics Approaches in Rhizosphere Microbiology: Part A series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Maize Agriculture

    Remote Sensing, Artificial Intelligence, and Advance Phenotyping
    • 1st Edition
    • Sheikh Mansoor + 5 more
    • English
    As the global population approaches 9 billion, the pressure on agriculture to produce sufficient food will escalate, leading to significant challenges in sustainable food production. Maize Agriculture addresses the urgent need to develop improved maize cultivars grown under advanced technological conditions to combat these future food shortages and nutritional deficiencies. Furthermore, climate change, with its impacts on temperature, precipitation, carbon dioxide levels, and the frequency and severity of extreme weather events, is likely to significantly affect soil water availability, carbon storage, and crop yields. This book digs into these pressing issues, offering an in-depth exploration review of the latest technologies in maize research. This comprehensive resource covers a wide range of topics essential for modern maize agriculture. Beginning with an overview of global maize production, the book progresses through chapters on advanced phenotyping platforms for sustainable maize production. Following that, it explores the integration of genomics and phenomics for maize breeding and the application of AI and machine learning models for genomic trait prediction. Further chapters discuss the use of GIS and global databases for agricultural planning, remote sensing for biotic and abiotic stress monitoring, and advanced AI-based approaches for disease management. Each chapter is carefully structured to provide in-depth insights and practical applications, ensuring a thorough understanding of the subject matter. Maize Agriculture is an invaluable resource for upper-level undergraduate students and researcher across various life science and agriculture disciplines, including agriculture, horticulture, botany, biochemistry, and biotechnology. Additionally, maize breeders, agronomists, and agricultural professionals engaged in maize research will find the actionable strategies in this book invaluable. By integrating digital tools with traditional farming practices, this book ensures that readers are prepared for the future of maize agriculture.

  • AI and Global Health

    Unlocking Transformative Potential
    • 1st Edition
    • Adil Haider
    • English
    AI and Global Health: Unlocking Transformative Potential provides a roadmap for practitioners to apply and leverage artificial intelligence to strengthen health systems using the World Health Organization's health systems approach. The book's combination of case studies and secondary research inspires the possibility of what can happen using AI in healthcare, ensuring the use of robust, scientific evidence to draw conclusions. Additionally, readers will learn from others in settings where AI has been a tool for change, providing healthcare practitioners and policymakers with what they need to think through how it can be applied in resource limited settings.The book provides a strong call to action for policymakers and healthcare leaders of governments, international organizations, and healthcare institutions to take the lead in AI implementation as a key lever for advancing global health goals through a systems approach. As AI is a rapidly evolving field with significant investment made in this industry in recent years from government and the private sector, this book articulates how this growth can be harnessed for countries that need a different approach to addressing global health problems.

  • Molecular Mechanisms of Cancer Resistance

    Emerging Technologies and Therapeutic Strategies
    • 1st Edition
    • Ahmet Acar
    • English
    Molecular Mechanisms of Cancer Resistance: Emerging Technologies and Therapeutic Strategies explores innovative tools and strategies designed to address the critical issue of drug resistance in cancer treatment. This comprehensive volume is tailored for researchers, clinicians, and students, offering insights into the latest advancements and methodologies in the field. The book covers essential topics such as molecular mechanisms of drug resistance, the tumor microenvironment, and emerging technologies like single-cell analysis and computational modeling. Each chapter features contributions from leading experts, providing a multi-dimensional perspective on both foundational concepts and cutting-edge research.By engaging with this book, the academic audience gains access to groundbreaking research and therapeutic strategies that enhance understanding and practice. The knowledge acquired will inspire collaboration and innovation, ultimately contributing to more effective and personalized cancer treatment approaches.

  • Genetic Advances in Inborn Errors of Immunity

    • 1st Edition
    • Volume 117
    • English
    Genetic advances in inborn errors of immunity, published as Volume 117 of the serial Advances in Genetics, provides a comprehensive and up‑to‑date overview of the rapidly evolving genetic landscape underlying inborn errors of immunity (IEI). Bringing together authoritative contributions from leading experts, this volume examines how advances in genomics, molecular diagnostics, and functional immunology have transformed the understanding, classification, and clinical management of primary immunodeficiency disorders. The chapters span severe monogenic conditions to complex, polygenic phenotypes, highlighting both mechanistic insights and translational implications. Collectively, the volume serves as an essential reference for researchers and clinicians seeking to understand how genetic discoveries are reshaping immunology and precision medicine.

  • Advances in Agronomy

    • 1st Edition
    • Volume 201
    • English
    Advances in Agronomy, Volume 201, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • High Amylose Cereals

    Impact of Starch Structure and Processing on Nutrition
    • 1st Edition
    • Nese Sreenivasulu + 2 more
    • English
    High Amylose Cereals: Impact of Starch Structure and Processing on Nutrition provides a complete focused reference on resistant starch, its source and its efficient and effective use as part of a healthy diet. Moving the reader from the plant to the product, it guides the reader to greater understanding of the potential for these grains. High amylose starch provides a meaningful amount of dietary fiber through the delivery of starch resistant to digestion. This characteristic provides a mechanism to increase the global consumption of fiber. As high amylose grains are being developed and commercialized, a reference is needed describing the general background, nutritional benefits, underlying trait development, and product development. The scope of this book includes topics ranging from the genetics required for the plant to develop high amylose starch to the nuances of creating finished food products with high amylose grain ingredients, including post-harvest processing technologies, and potential for delivering health benefits to consumers. Edited and contributed by leading experts, the book will be valuable for those seeking to understand the role high amylose cereals can play in the global food supply.

  • Human-AI-Cognitive Intelligence Software, System, and Services for Quality Assurance

    Theories and Methods with Systems Thinking for Behaviour Change in the Medical Decision-Making Pathway
    • 1st Edition
    • Pantea Keikhosrokiani
    • English
    Habit-based Behavior Change Medical Information Support System and Artificial Intelligence: Theories, Methods, and Data Analytics Approach provides a guideline to design and implement Habit-based Behavior Change Support Systems (HBCSS) which can change patient’s unhealthy habits to prevent the development of diseases. It presents theories, methods, management, and data analytics approach required to design, implement, and prescribe the use of HBCSS for several diseases’ management.It discusses topics such as theories of behavior change, ontologies and knowledge management, data mining, privacy and security, descriptive and prescription analytics. In addition, it discusses how to measure habit-change, future directions of the field, and case studies based on real-world examples.It is a valuable resource for clinicians, researchers, students, and member of the biomedical and medical fields who want to learn more about the use of medical systems to improve patients’ health.

  • Glial Mechanisms in Sleep and Circadian Biology

    • 1st Edition
    • Marcos G. Frank
    • English
    Glial Mechanisms in Sleep and Circadian Biology presents a comprehensive and up-to-date discussion of the role of glial cells in numerous, often unexpected, aspects of sleep. It seamlessly links glial cell activity to the multi-system processes that affect sleep. Experts in the field discuss how glial cells influence the sleep-wake cycle, the accumulation and discharge of sleep drive, the timing of sleep and wake across the 24-hour day, and how glial cells may govern important sleep functions (e.g., brain plasticity and metabolism). This is a book that could well change scientists’ and practitioners’ traditional beliefs about the factors underlying sleep.Users will find the book's content at the forefront of one of the hottest topics in basic sleep research. Over the last decade, scientists have made breakthrough discoveries revealing that sleep is not only a product of neurons, but of neuronal-glial interactions.

  • AI-Driven Plant Science

    Advancing Crop Performance Through Omics Integration and Physiology
    • 1st Edition
    • Osamah Shihab Albahrey + 1 more
    • English
    AI-Driven Plant Science: Advancing Crop Performance Through Omics Integration and Physiology offers cutting-edge insights into the rapidly evolving fields of precision agriculture, Artificial Intelligence, plant biotechnology and genetic engineering, and bioinformatics. With a strong focus on applications in smart agriculture, crop improvement, and environmental adaptation, it bridges the gap between advanced research and practical implementation. The rapid advancements in AI and biotechnology have created both opportunities and complexities for the agricultural sector. This book fills a critical gap in the existing literature by providing a multidisciplinary resource that integrates AI, biotechnology, and agricultural science. While there are numerous resources on plant biology and AI individually, few works explore their synergistic potential in depth. This book offers actionable insights into how AI can revolutionize crop physiology, stress tolerance, and plant-based research. It also highlights the challenges and ethical considerations of integrating AI into agricultural practices, ensuring a balanced and forward-thinking perspective. AI-Driven Plant Science: Advancing Crop Performance Through Omics Integration and Physiology provides a definitive guide for researchers, industry professionals, and students seeking to understand and apply AI in plant science and crop production.

  • The Role of Machine Learning and Artificial Intelligence in Revolutionizing Healthcare

    • 1st Edition
    • Prashant Kesharwani + 1 more
    • English
    Revolutionizing Healthcare: The Role of Machine Learning and Artificial Intelligence describes the complexity of healthcare data that necessitates the expanding use of artificial intelligence (AI). This book offers an explicit accounting of vital aspects on artificial intelligence in healthcare, discussing perspectives of the technologies explored based on findings outlined in highly organized tables, illustrative figures, and flow charts. It brings together novel applications of artificial intelligence in healthcare and helps readers define major gaps in knowledge that can lead to significant scientific discoveries.In addition, the book covers computational drug design, genomic data mining, nanomedicines, medical devices, cosmeceuticals, biosensors, genome counseling, quality control, clinical trials, and cybersecurity. Researchers, students, and scientists will find the book provides foundational and practical knowledge, along with the most advanced AI applications in healthcare.

  • Biology of Aging Accelerators

    Fundamentals, Hallmarks and Therapeutic Interventions
    • 1st Edition
    • Sandeep Kumar Singh + 1 more
    • English
    Biology of Aging Accelerators: Fundamentals, Hallmarks and Therapeutic Interventions explores how biological, genetic, and environmental factors affect cellular and systemic homeostasis and lead to accelerated aging. The book begins with a historical perspectives, highlighting the growth in immune system deterioration, chronic illness, and social issues. It then examines the hallmarks of aging, including primary, antagonistic, and integrative characteristics that may or may not be contributors. Subsequent chapters explore basic concepts and key accelerators in human biology, the role of biological clocks, and mechanisms of aging accelerators such as cellular senescence, DNA damage, and mitochondrial dysfunction.The book also addresses how different organs age at different rates and the brain's role as the body's aging integrator and provides actionable insights into innovative therapies aimed at reducing or stopping the signs and symptoms of aging, including developments in medications, lifestyle adjustments, regenerative medicine, and cutting-edge technologies like stem cell therapy and CRISPR. By integrating scientific research and practical insights, this book offers a realistic perspective on anti-aging research and stimulates novel ideas for improving quality of life.

  • GANs in Medical Diagnostics and Classification

    • 1st Edition
    • Abhishek Kumar + 1 more
    • English
    GANs in Medical Diagnostics and Classification explores the role of Generative Adversarial Networks (GANs) in addressing underdiagnosed and overlooked health challenges. The book bridges cutting-edge AI research with real-world medical applications, presenting interdisciplinary insights into how GANs enhance diagnostics, treatment precision, and disease surveillance across domains such as antimicrobial resistance, rare genetic disorders, and environmental health risks. It also examines ethical, policy, and accessibility dimensions of AI in healthcare. By combining technical depth with practical case studies, this volume equips medical researchers, AI engineers, and healthcare professionals with actionable knowledge to tackle silent epidemics using GAN-based tools.

  • Aging and Troponin

    Clinical Implications and Uses Beyond Diagnosis
    • 1st Edition
    • Gary Tse + 3 more
    • English
    Aging and Troponin: Clinical Implications and Uses Beyond Diagnosis examines the multifaceted role of troponin in clinical medicine, with a special focus on aging. This comprehensive reference provides essential technical knowledge, diagnostic and prognostic applications, and model development insights from leading experts in clinical biochemistry, pathology, and epidemiology. The book emphasizes the impact of aging on troponin test results and their interpretation, addressing age-related disorders such as renal failure. Sections cover the technical aspects of troponin assays, comparing traditional and high-sensitivity assays and exploring point-of-care testing advancements.The book also examine age-related changes and intra- and inter-individual variability in troponin levels, focuses on diagnostic applications, including troponin as a biomarker for cardiac injury and dysfunction, and the effects of age, sex, and renal impairment on diagnostic sensitivity and specificity, and discusses troponin's prognostic value for mortality in various conditions, including heart disease, sepsis, and COVID-19, and its role as a marker of organ biological age. The final section offers cutting-edge insights into the clinical applicability of troponin testing, highlighting the benefits of incorporating high-sensitivity assays into clinical workflows and providing perspectives and age-related considerations from practicing physicians on implementation and evidence-based practice.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 136
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Geographic Atrophy in Age-related Macular Degeneration

    • 1st Edition
    • Jay Chhablani + 1 more
    • English
    Geographic Atrophy in Age-related Macular Degeneration provides a comprehensive resource on this flourishing discipline, focusing on accurate diagnosis, imaging features, clinical trials, differential diagnoses, and both established and emerging treatment options. The book details diagnostic processes using techniques such as visual acuity tests, dilated eye exams, fundus photography, optical coherence tomography (OCT), and fluorescein angiography, emphasizing the importance of early detection. It also differentiates geographic atrophy from other retinal conditions with similar symptoms, such as dystrophies, equipping practitioners with the knowledge for accurate diagnosis.Additional... it explores traditional management approaches like antioxidant supplements, lifestyle changes, and low vision aids, alongside novel treatments such as complement inhibitors, cell-based therapies, and gene therapy, to inform clinicians about the latest advancements and research in patient care. With the recent FDA approval for GA treatment, there has been significant interest in the retina community. This rapidly growing field necessitates a new book on geographic atrophy in age-related macular degeneration to address gaps in existing literature and provide up-to-date, comprehensive information.

  • Animal Cognition

    Fundamentals, Models, and Therapeutic Advances
    • 1st Edition
    • Shampa Ghosh + 3 more
    • English
    Animal Cognition: Fundamentals, Models, and Therapeutic Advances provides a comprehensive overview of cognitive processes in various animal species, spanning fundamental concepts, species-specific studies, and therapeutic applications. Sections cover the foundation of animal cognition, including definitions, key concepts, and an overview of cognitive abilities, such as memory, problem-solving, and learning, delve deeper into the cognitive processes in mammals, birds, and marine animals, and more, and review the latest technological advancements in studying cognition, such as neuroimaging, machine learning, and virtual reality. With a multidisciplinary approach, this volume highlights current research while identifying gaps for future exploration, and will be of interest to researchers involved in animal cognition and behavioral neuroscience.

  • Gallin and Ognibene's Principles and Practice of Clinical Research

    • 5th Edition
    • John I. Gallin + 2 more
    • English
    Gallin and Ognibene’s Principles and Practice of Clinical Research, Fifth Edition provides the definitive text on clinical research as written by internationally recognized experts from the National Institutes of Health, the US Food and Drug Administration, academia, and global researchers. This new edition contains more than 30 new authors and 9 new chapters. Topics covered emphasize the role of informatics in clinical research, incorporating clinical outcome assessment into endpoints for decision-making, inclusion of diverse and vulnerable research subjects, patient advocacy groups, rare disease research, preparing research for pandemics, public health emergencies, research opportunities for surgeons, and content on preclinical animal studies.For the international researcher, two new chapters detail international clinical research experiences in South Africa, India, and Pakistan. As with the previous edition, the new release provides readers with summary questions and answers after each chapter.

  • Essentials of Stem Cell Biology

    • 4th Edition
    • Robert Lanza + 1 more
    • English
    Essentials of Stem Cell Biology, Fourth Edition is designed for the growing community of scientists, researchers, practitioners, and students embracing the latest advancements in stem cells. This comprehensive book, a collaboration of 7 editors and over 200 pioneering scholars and scientists, provides a thorough understanding of adult and embryonic stem cells. It combines fundamental concepts with cutting-edge research in specific organ systems, ensuring a robust foundation for anyone entering the field. Beyond the basics, the book delves into early development and the differentiation of ectoderm, mesoderm, and endoderm.It covers methods, applications to human diseases, regulation, ethics, and patient perspectives, leaving no stone unturned in the stem cell domain.

  • Current Advances in Cancer Stem Cells and Neoplasia Research

    • 1st Edition
    • Hirendra Banerjee
    • English
    "Cancer, Volume 8" in the "Stem Cell Innovation in Health and Disease" series explores the rapidly evolving role of stem cells in cancer treatment. As cancer continues to impose a heavy global health burden, stem cell therapies are being recognized for their regenerative potential and ability to enhance recovery following aggressive therapies. Hematopoietic stem cell (HSC) transplantation is already a standard, FDA-approved treatment for hematologic cancers such as leukemia, myeloma, and lymphoma. These cells help regenerate healthy blood cells post-treatment. In addition, mesenchymal stem cells (MSCs) and neural stem cells (NSCs) are showing promise in preclinical models as therapeutic carriers, capable of homing to tumor sites and delivering anti-cancer agents such as nanoparticles, siRNAs, and small-molecule drugs. Recent clinical advancements include differentiation therapy, where stem cells are used to induce cancer cells to become non-cancerous. Two completed phase I clinical trials have demonstrated innovative applications: one using NSCs to convert a prodrug into a toxic compound within tumors, and another using MSCs engineered with viral enzymes to activate cytotoxic drugs directly at the tumor site. MSCs have also helped reduce graft-versus-host disease (GVHD), a major complication of stem cell transplants. This volume is divided into two main sections: understanding stem cell roles in cancer biology, and translating stem cell innovations into clinical practice. It features cutting-edge research, including organoid models, genetic editing, and iPSC technologies. Together, these insights offer a timely review of the field’s progress and its real-world potential to reshape cancer therapy.

  • Fluid Dynamics of Viral Transmission

    • 1st Edition
    • Mehrzad Shams + 1 more
    • English
    Fluid Dynamics of Viral Transmission is an essential exploration into the transmission dynamics of COVID-19, focusing specifically on the airborne spread of respiratory aerosols carrying infectious viruses. In light of the recent global pandemic, it offers crucial insights into the complex interaction between fluid dynamics and viral transmission and provides practical solutions for minimizing risks in indoor environments. The book delves into CFD simulations, optimizing ventilation systems, air filtration strategies, and spatial layout modifications. It evaluates mitigation measures such as mask-wearing, physical distancing, and occupancy limits, aiming to equip readers with the knowledge to create safer indoor spaces. This book is ideal for public health officials, policymakers, healthcare professionals, engineers, researchers, and academics in fluid mechanics, computational fluid dynamics, epidemiology, and virology.

  • Oil-Encapsulated Powders for Functional Foods

    Preparation and Practice
    • 1st Edition
    • Jian Zhong + 2 more
    • English
    The development of functional foods enriched with health-promoting, oil-based bioactives has become a central focus for researchers and industry professionals seeking to meet growing consumer demand for healthier options. Oil-Encapsulated Powders for Functional Foods: Preparation and Practice provides an in-depth, guide to overcoming the scientific and technical challenges associated with stabilizing and delivering sensitive oils in food matrices. This comprehensive volume offers detailed insights into encapsulation science, advanced preparation techniques, and practical application strategies essential for creating effective, stable, and appealing functional foods. Covering core materials such as oils and wall substances, state-of-the-art encapsulation and drying methods, and robust characterization techniques, Oil-Encapsulated Powders for Functional Foods: Preparation and Practice bridges the gap between fundamental research and industrial practice. It emphasizes how encapsulation can enhance bioavailability, protect bioactives from environmental degradation, and improve sensory attributes. With real-world examples spanning formula foods, meat, dairy, and bakery products, it is an essential resource for food scientists, nutritionists, and product developers dedicated to innovating health-oriented foods that meet modern consumer needs and promote overall wellness.

  • Empowering Health through Lifestyle Medicine

    The Essential Guide for Preventing and Managing Chronic Disease
    • 1st Edition
    • John Anthony Stevens
    • English
    Empowering Health through Lifestyle Medicine: The Essential Guide for Preventing and Managing Chronic Disease is an evidenced-based health discipline for use by anyone in the healthcare profession including clinicians and public health and for those researching illness prevention and chronic disease management to improve health research practice and patient outcomes. Combining the best available research with personal insights and experience and using the Lifestyle Medicine 6 pillar framework, the book engages readers not only in the description and efficacy of LM but also in the knowledge, concepts and behaviors to better prevent and manage nutrition, physical activity, stress, mental health as well our interaction with the environment for a healthier, happier life. This is a book should encourage clinicians to engage their patients more often and more practically with lifestyle medicine, and consumers to better engage with their clinicians, and to more effectively self-manage their own health in preventing and managing lifestyle-related illness for life.

  • Biomarkers in Neurological Disorders and Treatment

    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Decoding the Brain: Biomarkers in Neurological Disorders and Treatment provides a comprehensive exploration of the latest advances in neurological biomarkers, detailing their discovery, validation, and application in clinical practice. By offering insights into the biological underpinnings of various neurological disorders, this book aims to bridge the gap between cutting-edge biomarker research and its practical implementation in patient care.

  • Nutritional Treatments for Liver Disease

    The Effects of Food and Plants
    • 1st Edition
    • Erika Ramos-Tovar + 1 more
    • English
    Nutritional Treatments for Liver Disease: The Effects of Food and Plants offers an essential, comprehensive guide to leveraging nutritional science in the prevention and treatment of liver diseases. Authored by leading research experts in the fields of experimental liver disease and the effects of herbal compounds, and the pathophysiology and pharmacology of liver diseases, this volume synthesizes cutting-edge research on the therapeutic efficacy of functional foods, medicinal plants, vitamins, and gut microbiota modulation for hepatic disorders. Liver diseases represent a significant global health burden with limited pharmacological options. Nutritional Treatments for Liver Disease: The Effects of Food and Plants addresses this gap by detailing the cellular and molecular mechanisms through which natural and synthetic nutritional compounds exert protective, anti-inflammatory, antifibrotic, and antiviral effects on the liver. Topics include the epidemiology of liver diseases, malnutrition complications, and the role of key bioactive compounds such as silymarin, curcumin, quercetin, coffee, and various vitamins. Designed for researchers, clinicians, nutritionists, and students alike, this authoritative resource combines scientific rigor with practical insights to foster advanced understanding and inspire novel therapeutic strategies in liver disease management.

  • Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine

    • 1st Edition
    • Cheng Xue + 3 more
    • English
    Molecular Insights for Harnessing Urine Biomarkers in Precision Medicine provides a comprehensive exploration into the molecular signatures and clinical implications of urine biomarkers, providing invaluable insights for clinicians, researchers, and healthcare professionals. From historical perspectives to cutting-edge technologies, this reference presents an updated understanding of urine biomarkers' role across diverse bodily systems. With sections devoted to fundamental concepts, molecular signatures, and clinical applications, readers gain a deep understanding of urine biomarkers' significance in disease diagnosis and personalized medicine.Each chapter explores specific body systems, including renal, urological, cardiovascular, and respiratory, uncovering the diagnostic potential of urine biomarkers in various conditions like cancer, cardiovascular diseases, and neurological disorders. Highlighted are the latest advances in technology, challenges, and future directions, keeping readers abreast of the rapidly evolving landscape of urine biomarker research. Real-world case studies illustrate practical applications, enhancing comprehension and facilitating knowledge transfer to clinical practice.

  • Human Reproduction

    From basics to Biotechnology
    • 1st Edition
    • Marc yeste
    • English
    Human Reproduction: From Basics to Biotechnology is a complete reference for anyone in the field of life, health, and biomedical sciences. The book provides an overview of basics in human reproduction to advanced knowledge of the field, including some evidence from other mammalian species that complement our current knowledge on the anatomy and physiology of the male and female reproductive tract and gametes. This resource covers the most used assisted reproductive techniques and technical advances, human reproduction and infertility disorders, their diagnosis and available treatment options.

  • Thiamine Pyrophosphate (TPP)-Dependent Enzymes

    • 1st Edition
    • Volume 736
    • English
    Methods in Enzymology: Thiamine pyrophosphate-depend... enzymes Thiamine pyrophosphate (TPP)-dependent enzymes are a diverse group of ubiquitous enzymes. They have in common the use of the biologically active form of vitamin B1 as a cofactor, which gives them the ability to catalyze the formation or cleavage of carbon-sulfur, carbon-oxygen, carbon-nitrogen, and especially carbon-carbon bonds. The specific characteristics of TPP-dependent enzymes, related to both the chemistry of thiamine pyrophosphate and their organization into multimeric subunits, have always aroused the interest of scientists. During these last years they developed original experimental approaches, and also new analytical tools to study, understand and modulate the activity of these enzymes. In the first section of this volume, we propose to address a wide range of methods related to TPP-dependent enzymes as target in health and agrochemistry. Then in a second section, we will focus more particularly on TPP-dependent enzymes in biocatalysis, and in particular on the associated techniques in the field of enzymatic engineering and repurposing. In a third section, we will then address an exciting topic, namely that of the assimilation of one-carbon compounds such as formaldehyde. We will see how TPP enzymes are a tool of choice in biotechnology to address this issue. Finally, we will focus on dual cofactor TPP-dependent enzymes and multi-enzyme complexes using structural and metabolic approaches.

  • The Metabolon

    • 1st Edition
    • Volume 739
    • English
    Methods in Enzymology series: The Metabolon, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology

    • 1st Edition
    • Swagat Kumar Das + 2 more
    • English
    Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology delves into historical perspectives, current trends, and future projections for research and development of immunological and biopharmaceutical products. Sections explore immunostimulants, natural and synthetic immunostimulants in aquaculture and animal husbandry, immunomodulators, immune boosters, pre- and probiotics in health promotion, cutting-edge immunological techniques for disease diagnosis, immunotherapy in cancer treatment, and transplantation immunology. Following chapters explore the impact on pharmaceutical biotechnology, with discussions on traditional and modern approaches in drug delivery, in silico drug delivery modeling, biocomposites and their pharmaceutical applications, recent advances in monoclonal antibodies production, vaccine development, and much more. Finally, the book covers the pivotal role of AI, machine learning, and data analytics in the clinical study of immunotherapy and pharmaceutical drugs, thus paving the way for enhanced research and development efficiency. Researchers in industry and academia alike will gain valuable insights into the novel principles behind designing and developing immunological and drug products, making this title an essential resource.

  • Sleep Neurology

    • 1st Edition
    • Anne Marie Morse
    • English
    Sleep Neurology explores the intricate relationship between sleep and neurological health, bridging the gap between theoretical knowledge and practical application. This comprehensive reference highlights the role of sleep in overall health and provides an examination of how sleep influences a wide range of neurological disorders. From neurodevelopmental issues to neurodegenerative diseases, this book offers a detailed review of how sleep science can be applied to improve patient outcomes in various neurological conditions. Structured around key neurological topics, the book offers insights into conditions such as epilepsy, stroke, and traumatic brain injury, emphasizing the importance of sleep management in their treatment. Each chapter not only discusses the scientific underpinnings of sleep but also provides tangible strategies for integrating sleep health into primary neurological care.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 137
    • English
    Advances in Applied Microbiology presents the latest developments and innovative research in applied microbiology, covering topics such as microbial biotechnology, environmental applications, industrial processes, and medical advancements. It offers valuable insights into the practical uses of microorganisms in solving real-world challenges, making it an essential resource for researchers, professionals, and students in microbiology and related fields.

  • Epigenetics and miRNA in Neurodegenerative Diseases

    From Molecular Mechanisms to Clinical Applications
    • 1st Edition
    • Lance R. McMahon + 2 more
    • English
    Epigenetics and miRNA in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications explores the crucial role of epigenetic modifications and microRNAs in the onset, progression, and treatment of neurodegenerative disorders such as Alzheimer’s, Parkinson’s, ALS, and Huntington’s disease. This comprehensive book bridges cutting-edge molecular research with real-world clinical applications, covering biomarker discovery, novel therapeutics, gene editing, and AI-driven bioinformatics. With clear explanations, case studies, and future perspectives, it serves as an essential resource for researchers, clinicians, and biotech professionals working toward innovative solutions for neurodegenerative disease diagnosis and treatment

  • Diabetic Neuropathy

    • 1st Edition
    • Shahidul Islam
    • English
    "Recent Therapeutic Targets for the Prevention and Management of Diabetic Complications: Neuropathy" covers recent research and therapeutic approaches of this diabetic complication for the management of diabetes. It is a detailed reference to understand the pathogenesis of diabetes to alleviate the overall complications of neuropathy to improve patient care. It is uniquely focused on the different aspects of neuropathy with a focus on the molecular and biological pathways (therapeutic target) to detect an early diagnosis to better manage the disease and improve patient care. The book is useful to anyone in the field particularly those who do research investigations, and day-to-day practice in the area of diabetes.

  • Lysosomal Pathophysiology of Parkinson’s Disease

    • 1st Edition
    • Mattia Volta + 1 more
    • English
    Lysosomal Pathophysiology of Parkinson’s Disease delves into the genetic and genomic revelations that have transformed our understanding of Parkinson’s Disease at the molecular level. The book highlights the critical role of the autophagy-lysosome pathway in the disease's pathogenic processes, drawing a comprehensive timeline of disease onset and progression. It offers a detailed examination of how disruptions in this pathway contribute to the hallmarks of Parkinson’s Disease, providing invaluable insights for researchers and clinicians alike. Subsequent chapters extend these insights by comparing Parkinson’s Disease to other neurodegenerative disorders such as Alzheimer’s Disease and Frontotemporal Dementia. By exploring protein pathology and synaptic alterations, the book underscores the broader implications of autophagy-lysosome dysfunction. Additionally, it discusses how the molecular perspectives gleaned from Parkinson’s Disease can inform our understanding of these other conditions, presenting a unified approach to studying neurodegeneration.

  • Gold Nanoparticle Therapeutics in Alzheimer's Disease

    Revolutionizing Diagnosis and Treatment
    • 1st Edition
    • Arun Kumar Singh + 2 more
    • English
    Gold Nanoparticle Therapeutics in Alzheimer's Disease: Revolutionizing Diagnosis and Treatment is an essential resource that delves into the groundbreaking use of nanotechnology in the fight against one of the most challenging neurodegenerative disorders. This volume offers an in-depth exploration on how gold nanoparticles can be used to enhance the diagnosis, treatment, and overall understanding of Alzheimer's disease. By examining the molecular mechanisms that enable nanoparticles to cross the blood-brain barrier, the book highlights their role in inhibiting amyloid fibrils and their potential as precise diagnostic tools.Covering a wide range of topics, this comprehensive guide serves as an invaluable reference for researchers, clinicians, and industry professionals at the forefront of Alzheimer's research and nanomedicine.

  • Drug Discovery

    Traditional Approaches and Advanced Strategies
    • 1st Edition
    • Renren Bai
    • English
    Drug Discovery: Traditional Approaches and Advanced Strategies is a foundational monograph that connects established methodologies, cutting-edge technologies, and the transformative impact of AI and other emerging tools in the drug discovery landscape. Sections provide an overview of drug discovery and development, introducing current trends and the evolving landscape of the field, explore traditional approaches alongside advanced strategies, covering topics such as drug target discovery, lead optimization, and the revolutionary role of artificial intelligence in drug discovery, and investigate promising emerging technologies, including targeted protein degradation and innovative design strategies. Equipping readers with insights into the future of drug development, this is a vital resource for academic and industrial researchers, students, and professionals seeking to stay at the forefront of drug discovery. By integrating traditional methodologies with the latest advancements, this book not only enhances understanding but also inspires innovation. With practical case studies and real-world applications, it empowers researchers to effectively implement new technologies, ultimately improving the efficiency and success rates of their R&D endeavors.

  • The NeuroComplex Interaction of Appetite Regulation

    Brain, Body and Environment
    • 1st Edition
    • Nasrollah Moradikor + 1 more
    • English
    The NeuroComplex Interaction of Appetite Regulation: Brain, Body and Environment presents the latest research on why we eat, what makes us hungry, and how our brain controls our cravings. The book covers the data for how the brain, hormones, and different factors such as stress, the environment, and even food itself affects our desire to eat. Written for academics and researchers, this book helps facilitate a comprehensive understanding on how the brain influences appetite regulation, allowing readers to understand how neurobiological mechanisms can help treat patients involved with obesity, eating disorders, or other related conditions.Readers will find this to be a reliable resource that connects current neuroscience research with practical applications in appetite and behavior.

  • Principles of Antiviral Drug Development

    Rapid Discovery Technologies and Practical Applications
    • 1st Edition
    • Ailin Liu
    • English
    Principles of Antiviral Drug Development: Rapid Discovery Technologies and Practical Applications systematically integrates the major experimental techniques and virtual drug screening methods involved in the discovery of antiviral drugs, and provides a detailed discussion of their applications: among them, the combination of virtual drug screening technologies coupled with experimental methods offers strong potential for the rapid discovery of antiviral agents. The book also discusses activity-guided extraction, isolation, and activity evaluation of active components in order to reveal the material basis of antiviral activity and preliminary mechanisms of action. The book also discusses: drug repurposing of approved medicines; and an analysis of the discovery and mechanistic studies of a series of antiviral natural products which offer important information on the needs of future research, development, together with the clinical application of new antiviral drugs.

  • Green Polymeric Materials in Drug Delivery

    Sustainable Solutions for Therapeutic Applications
    • 1st Edition
    • Parteek Prasher + 5 more
    • English
    Green Polymeric Materials in Drug Delivery: Sustainable Solutions for Therapeutic Applications addresses the critical intersection of polymer science, pharmaceutical technology, and environmental sustainability. This reference responds to the urgent need for eco-friendly drug delivery systems that improve therapeutic outcomes while minimizing ecological impact. It offers researchers and professionals a detailed exploration of green polymers derived from renewable sources and their transformative potential in healthcare. The comprehensive contents cover fundamental principles, synthesis, biocompatibility, formulation strategies, and innovative applications including nanomaterials, hydrogels, vesicular systems, and vaccine delivery. Chapters authored by leading experts examine targeted delivery routes such as mucosal, ocular, transdermal, and neural pathways. Regulatory frameworks and clinical trial insights further support translation from research to practice. Emerging technologies like AI-assisted formulation and 3D printing of implants are also discussed. This reference benefits polymer chemists, pharmaceutical scientists, regulatory experts, and clinicians by providing authoritative knowledge on sustainable materials for drug delivery. It equips readers with the scientific foundation and practical case studies necessary to advance green polymeric technologies in therapeutic development, fostering a sustainable future in pharmaceutical innovation and patient care.

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