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Books in Life sciences

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    • Invertebrate Cell Culture Applications

      • 1st Edition
      • December 2, 2012
      • Karl Maramorosch
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 5 6 9 1
      • Hardback
        9 7 8 0 1 2 4 7 0 2 9 0 5
      • eBook
        9 7 8 0 3 2 3 1 5 8 8 3 1
      Invertebrate Cell Culture Applications assesses the status of invertebrate cell culture at a time when this method can be used to solve problems in a number of diverse disciplines. Organized into seven chapters, this book begins by discussing the development and amino acid requirements of insect cell culture. It then describes the Drosophila tissue culture and chromosomal phenomena in cell lines of this organism. This book also explains the culture conditions regulating the infection of cells by an intracellular microorganism, as well as the replication of arboviruses in arthropod in vitro systems. Lastly, the characteristics, growth requirements, and applications of tick cell culture to parasitology are explored. This book will contribute in solving biomedical and agricultural problems. This reference material will be of special interest to parasitologists, virologists, microbiologists, entomologists, geneticists, medical researchers, and graduate students in related fields of biomedical research.

    • Genomic and Personalized Medicine

      • 2nd Edition
      • October 30, 2012
      • Geoffrey S. Ginsburg + 1 more
      • English
      • eBook
        9 7 8 0 1 2 3 8 2 2 2 8 4
      Genomic and Personalized Medicine, Second Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003.

    • Olfaction and taste V

      • 1st Edition
      • December 2, 2012
      • Derek Denton
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 5 4 2 9
      • Hardback
        9 7 8 0 1 2 2 0 9 7 5 0 8
      • eBook
        9 7 8 0 3 2 3 1 4 8 6 1 0
      Olfaction and Taste V contains the proceedings of the Fifth International Symposium on Olfaction and Taste, held at the Howard Florey Institute of Experimental Physiology & Medicine, University of Melbourne, Australia, in October 1974. Contributors discuss the knowledge about olfaction and taste, including the anatomy of receptors and their ultrastructure, innervation of receptor fields, and the processes of receptor ""turnover"". Themes ranging from taste modifiers and receptor proteins to afferent coding; how the sensory code for taste and olfaction are processed and sharpened; and conditioned taste aversions and other taste learning effects in food and fluid intake are discussed. This book is organized into 14 sections encompassing 73 chapters and begins with an introduction to the phylogenetic origins of sweet taste. The discussion then shifts to behavior and the evolutionary emergence of the chemoreceptor systems. This book provides an overview of the basic modalities of taste throughout the vertebrate phylum, along with the powerful selection pressures that operate to contrive phylogenetic emergence of these modalities with attendant survival advantage. It also looks at each modality within the sensory organization of the species set against environmental circumstances during evolution that might be postulated as favoring its emergence and refinement, for example, the emergence of bitter in relation to poisoning. The ontogenesis of taste and some special instances such as chemoreception in aquatic animals are also examined. This book is aimed at students and scientists interested in the fascinating and important problems of chemoreception.

    • Nonhuman Primates in Biomedical Research

      • 2nd Edition
      • Volume 1
      • March 29, 2012
      • Christian R. Abee + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 3 8 1 3 6 5 7
      • eBook
        9 7 8 0 1 2 3 9 7 8 3 7 0
      The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Biology and Management volume provides basic information on the natural biology of nonhuman primates and the current state of knowledge regarding captive management. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject.

    • Cholesterol Metabolism, LDL, and the LDL Receptor

      • 1st Edition
      • December 2, 2012
      • N Myant
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 5 6 8 9
      • eBook
        9 7 8 0 3 2 3 1 4 8 8 7 0
      Cholesterol Metabolism, LDL, and the LDL Receptor focuses on the cholesterol biochemistry and lipoprotein metabolism. This book is organized into 10 chapters that describe the coordinated actions of three regulated processes, namely, the intracellular synthesis of cholesterol, its esterification by ACAT, and the receptor-mediated uptake of low-density lipoprotein (LDL), for optimal level of free cholesterol. The first five chapters explore the various aspects of cholesterol biology, including discussions on the interaction of ligands with their cell-surface receptors; the role of coated pits in the endocytosis of receptor-bound ligands; and the recycling of receptors through the interior of the cell. These chapters also examine the regulation of gene expression encoding inducible proteins and the use of natural and synthetic mutations in studies of the functions of the separate domains of a multifunctional protein. A chapter describes the cloning of the apoB gene, the receptor-binding domain of apoB-100, and the unusual mode of derivation of apoB-48. Considerable chapters are devoted to LDL receptor and its pathway. The concluding chapter deals with the clinical consequences of genetic dysfunction of the LDL receptor, with particular emphasis on the diagnostic and treatment approaches of familial hypercholesterolemia that are based wholly or in part on knowledge of the LDL receptor or its gene. This book is an indispensable guide for biologists, physiologists, and clinicians who are interested in the epidemiological field of cholesterol and heart attacks.

    • Bioregulators of Reproduction

      • 1st Edition
      • December 2, 2012
      • David Jagiello
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 1 8 6 7
      • eBook
        9 7 8 0 3 2 3 1 4 0 9 9 7
      Bioregulators of Reproduction focuses on the biological regulators of reproductive processes. Discussions are grouped based on sex differentiation and determination, germ cell reproduction, gonadotropins, nonsteroidal gonadal hormones, in vitro fertilization, and post-fertilization. This text is organized into six sections and comprised of 31 chapters, beginning with a discussion on the most important regulatory mechanisms underlying reproduction. The reader is then methodically introduced to the role of the H-Y antigen in primary sex determination, H-Y antigenic determinants of human testis-organizing protein, and how H-Y antibodies confuse antigenic complexes with unaltered self or allo-MHC antigens. The cellular mechanisms of sexual differentiation of the brain, meiosis in female mammals, and interspecies comparisons in molecular reproductive biology are also considered. Other chapters explore the role of haplodins in the ovarian and extraovarian control of meiosis; the link between nucleoprotein transitions and chromatin changes during rat spermatogenesis; and gonadotropin secretion in primates. This book will be of interest to students and scientists in fields ranging from biology and neuroendocrinology to genetics, biochemistry, biophysics, pathology, and zoology.

    • Molecular Pharmacology V3

      • 1st Edition
      • December 2, 2012
      • E.J. Ariens
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 3 9 6 8
      • eBook
        9 7 8 0 3 2 3 1 4 7 1 4 9
      Molecular Pharmacology: The Model of Action of Biologically Active Compounds, Volume 1 discusses the mode of action of bioactive compounds on a molecular level. This book reviews the processes that control the uptake of drugs, their diffusion through tissues, as well as their metabolism and excretion. Comprised of three sections, this volume starts with an overview of the different aspects of drug distribution and metabolism. This text then examines the totality of intermolecular processes or reactions between drug and receptor molecules, which is known as drug-receptor interaction. Other chapters explore the actions of various pharmacodynamic agents, including hormones and substances with selective toxicity, auxins, and odorants. This book discusses as well the ways in which the actions of drugs combine with the tissues and act upon themselves. The final chapter deals with the complicated types of relations between stimulus and effect. Pharmacologists and researchers will find this book useful.

    • Metabolic Maps of Pesticides

      • 1st Edition
      • December 2, 2012
      • Hiroyasu Aizawa
      • English
      • Paperback
        9 7 8 0 1 2 4 1 2 1 6 7 6
      • eBook
        9 7 8 0 3 2 3 1 4 0 7 5 1
      Metabolic Maps of Pesticides provides a summary of investigations and drawings of the metabolic patterns on pesticides that were collected with the aid of Chemical Abstracts Service (CAS) for the years 1970-1979. Some maps were taken from the original reports, some were slightly modified for clarity, and some were tentatively drawn from descriptions in the original articles. The pesticides are classified based on their chemical structures as functional groups or based on common chemical nomenclature. The chemical classifications highlight the properties of the mother pesticides and the impact of their degenerative metabolites on the environment. Metabolic maps are provided for the following: acid amides, amidines and guanidines, anilines and nitrobenzenes, biphenyl ethers, DDT and its analogs, dithio- and thiolcarbamates, five- and six-membered heterocyclic compounds, imides, organochlorine compounds, oxime carbamates, phenoxyacetic acids, pheny ring fused five-membered heterocyclic compounds, phenyl(aryl) carbamates, phenylureas and related compounds, phosphonothiolates and phosphonothioates, phosphonates, phosphorothioamides, phosphates, phosphorothiolates, pyrethroids, pyridines, triazines, and substituted benzenes and miscellaneous compounds.

    • Handbook of Flexible Manufacturing Systems

      • 1st Edition
      • December 2, 2012
      • Nand K. Jha
      • English
      • Paperback
        9 7 8 0 1 2 3 9 6 0 7 8 8
      • eBook
        9 7 8 0 3 2 3 1 3 9 3 5 9
      This handbook is a compilation of the current practical knowledge of flexible manufacturing systems (FMS). FMS allow manufacturing plants of all sizes to reduce their inventory while increasing their ability to meet consumer demands. By controlling automatic guided vehicles, robots, and machine tools with one central computer, products can now be produced in a variety of styles and models all at the same time. FMS are designed to adapt quickly and economically to changes in requirements and to unpredictable events. This guide explains how to effectively employ these useful new systems.

    • Natural Product Biosynthesis by Microorganisms and Plants Part C

      • 1st Edition
      • Volume 517
      • November 1, 2012
      • English
      • Hardback
        9 7 8 0 1 2 4 0 4 6 3 4 4
      • eBook
        9 7 8 0 1 2 4 0 4 6 1 7 7
      This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The third of 3 volumes covering Natural product biosynthesis by microorganisms and plants.

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