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Books in Life sciences

  • Ether Lipids Chemistry and Biology

    • 1st Edition
    • Fred Snyder
    • English
    Ether Lipids: Chemistry and Biology provides the major research breakthroughs in the chemistry and biology of ether lipids. This book contains 16 chapters and begins with the history of studies of ether lipids. The subsequent chapters deal with the chemical syntheses, analytical procedures, biological effects, and metabolic pathways of these lipids. Considerable chapters are devoted to the biochemical aspects of ether lipids in diverse species, such as mammals, birds, marine organisms, mollusks, protozoal, bacteria, and plants. These chapters also illustrate the suitability and usefulness of the various tissues to elucidate the role of these lipids in living systems. This text will be of value to chemists, biologists, biomedical scientists and researchers, and graduate students.

  • Isoelectric Focusing

    • 1st Edition
    • Nicholas Catsimpoolas
    • English
    Isoelectric Focusing deals with the theory and applications of isoelectric focusing. The book reviews some alternative approaches to generation of pH gradients for isoelectric focusing analysis, along with other relevant topics such as the theoretical aspects of steady-state isoelectric focusing, gel electrofocusing/gel electrophoresis, and transient state isoelectric focusing. This volume is organized into nine chapters and begins by looking at the history of the discovery of isoelectric focusing and correcting some blurred impressions conveyed in the literature. It then turns to a discussion of the differential equation of isoelectric focusing, the carrier ampholytes used in carrying out the technique, the use of isoelectric focusing in polyacrylamide and granulated gels as well as in free solution, and continuous-flow electrophoresis and isoelectric focusing. An attempt is made to illuminate problems in isoelectric focusing and to point out possible solutions in the areas of theory, mechanisms, ampholyte chemistry, and apparatus. Some of the processes that occur during an isoelectric focusing experiment are also considered. This book is intended for anyone who needs to know what isoelectric focusing is all about.

  • Lipid Metabolism

    • 1st Edition
    • Salih Wakil
    • English
    Lipid Metabolism focuses on the regulation and metabolism of lipids. This book is composed of 10 chapters that specifically deal with fatty acids, prostaglandins, glycerides, glycerophosphates, cholesterol, isoprenoids, and aromatic compounds. This text starts with an overview of fatty acid metabolism and its controlling factors. This topic is followed by discussions on the physiochemical aspects of oxidative metabolism of fatty acids, with a special emphasis on the role of carnitine in this process. A chapter highlights the several important aspects of higher plant lipid metabolism. Other chapters are devoted to the structures, biosynthesis, and metabolism of prostaglandins, bacterial lipids, phospholipids, glycerides, and steroids. The final chapters describe the biogenesis of aromatic substances through the polyketide path, including polyisoprenoid quinines and related compounds.

  • Leukocyte Membrane Determinants Regulating Immune Reactivity

    • 1st Edition
    • Vincent P. Eijsvoogel
    • English
    Leukocyte Membrane Determinants Regulating Immune Reactivity is a result of the Leukocyte Culture Conference meeting held at Amsterdam in 1975. Abstracts presented in the meeting are compiled in this book. The topics of these abstracts are all under leukocyte biology and include not just lymphocytes but also monocytes, macrophages, and granulocytes. The text is composed of six major sections. The first section features abstracts that deal with ligand binding and subsequent changes in membrane. Section II focuses on the receptors on lymphocytes in the context of various subpopulations. Immune reactivity, specifically its augmentation or suppression, is the main topic of Section III. Gene products are emphasized in Section IV, while effector functions of membrane determinants are tackled in Section V. Finally, Section VI features leukocyte membrane determinants in differentiation and maturation. The book presents much detailed information that will be of great help to students or professionals in the study of biology, specifically leukocyte biology.

  • Isoenzymes In Biology and Medicine

    • 1st Edition
    • Albert Latner
    • English
    Isoenzymes in Biology and Medicine attempts to give an account of the study of isoenzymes in relation to humans, animals, insects, higher plants, fungi, protozoa, algae, and bacteria. This book discusses the chemical structure, physiological aspects, metabolic role, and function of isoenzyme observations in genetic, ontogenic, and phylogenic studies. A detailed account of the use of isoenzyme in the diagnosis and pathogenesis of disease and control of therapy is also provided. This text likewise considers the isoenzymes of the oxidoreductases, transferases, and hydrolases, including its relation to clinical medicine. This publication is intended for biochemists, biologists, clinical biochemists and physicians.

  • Methods of Enzymatic analysis V4

    • 2nd Edition
    • Hans-UIrich Bergmeyer
    • English
    Methods of Enzymatic Analysis, Volume 4 reviews developments in the use of enzymes as tools in analytical biochemistry, including advances in assay techniques. It discusses the principles and methods for the elucidation of structures of enzymes, such as peptides, proteins, amino acids, fatty acid metabolites, lipids, steroids, nucleic acids, purines, pyrimidines, nucleosides, and coenzymes. It also considers the isolation and characterization of active centers in enzymes. This volume is divided into four parts, each discussing a group of enzymes and their determination. Part I focuses on proteins, peptides, and amino acids including amines and amides. Part II is concerned with fatty acid metabolites, lipids, and steroids ranging from polyunsaturated fatty acids and lecithin to choline, acetylcholine, triglycerides, glycerol, acetoacetate, triacetate, fumarylacetoacetate, 20-ketosteroids, prostaglandins, bile acids, and cholesterol. Part III discusses nucleic acids, purines, pyrimidines, nucleosides, coenzymes, and related compounds, whereas Part IV looks at other substrates and effectors such as inorganic phosphate. The book concludes with a chapter on metabolites and their concentrations in animal tissues. Biochemists as well as students and researchers working in the field of analytical biochemistry will find this book highly informative.

  • GPI Membrane Anchors

    • 1st Edition
    • M Almeida
    • English
    GPI Membrane Anchors reviews major advances in our understanding of glycosylphosphatidyl... (GPI) membrane anchors. The book examines the GPI structure and its originality as an anchoring device, its ubiquitous distribution, the main steps of its biosynthetic pathway, and the elegant means by which a protein signals for GPI attachment. It also presents evidence for the uniqueness of GPI as a tag in intracellular traffic and as a mediator of transmembrane signaling. This volume is organized into 20 chapters and begins with a discussion of the structural requirements of a nascent protein for processing to a PI-G anchored form, with emphasis on experiments on intact cells and cell-free systems. It then turns to the mechanisms underlying signal transduction by GPI-anchored membrane proteins, the LY-6 superfamily of GPI-anchored molecules, and glycosylated-phospha... as virulence factors in Leishmania. The reader is also introduced to the molecular biology of GPI-anchored border hydrolases, the role of GPIs and their inositolglycan derivatives in the mediation of insulin and growth factor function, and biosynthesis and cellular localization of GPI-modified glycoproteins in Saccharomyces cerevisiae. An account of electrospray mass spectrometry of a C-terminal peptide purified from the scrapie isoform of the scrapie prion protein is also given. The book concludes with a chapter on GPI-anchored recognition molecules that function in axonal fasciculation, growth, and guidance in the nervous system. This book is a valuable resource for students and researchers in the fields of cell biology and biochemistry.

  • Marijuana and Health Hazards

    Methodological Issues in Issues in Current Research
    • 1st Edition
    • Jared Tinklenberg
    • English
    Marijuana and Health Hazards: Methodological Issues in Current Research is a collection of manuscripts presented at a conference on methodological issues involving marijuana research, held in Washington, D.C., sponsored by the Drug Abuse Council Inc. This book is composed of five parts encompassing 18 chapters that focus on the human health consequences of marijuana consumption. Part I discusses the cytogenetic effects of marijuana, with an emphasis on its cell-damaging, genotoxic, and teratogenic effects. Part II describes the interaction of marijuana products on the T-lymphocytes of man and Part III examines the effects of marijuana smoking on male reproduction, specifically on plasma testosterone level. Part IV investigates the central nervous system damage associated with marijuana use and looks into some of the methodological problems arising at the general issues of central nervous system dysfunction as these relate to marijuana consumption. Part V focuses on the psychiatric consequences of different degrees of marijuana use. This book is of great benefit to scientists and researchers who wish to elucidate the issues regarding the effects of marijuana.

  • Genetics and Biotechnology of Bacilli, Volume 2

    • 1st Edition
    • A.T. Ganesan
    • English
    Genetics and Biotechnology of Bacilli, Volume 2 is a collection of papers from the "Fourth International Conference on Bacilli" held in California on June 21-24, 1987. One paper reviews the results of cloning and characterization of genes for secreted enzyme and of genes that control the expression of secreted enzymes in relation with other prokaryotic regulatory systems. Other papers tackle the regulation of gene expression during sporulation, the sigma factors, bacterial toxins, and antibiotic resistance genes. One paper reports that three genes responsible for the code for peptides found in BT cuboidal crystals have been successfully cloned. The three codes have different toxic characteristics in relation to tobacco hornworm larvae or mosquito larvae. Other papers examine replication. Such examination pertains to the two levels of control on the chromosome involved in DNA replication, or to the possible functional importance that several membranes associated DNA subcomplexes can have in Bacillus subtilis, where one of these appear to control initiation. Other papers discus secretion and extracellular enzymes, as well as, the different genetic systems and methods. This collection can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology, microchemistry, or toxicology.

  • Agricultural Engineering Soil Mechanics

    • 1st Edition
    • Volume 10
    • E. McKyes
    • English
    This book provides an introduction to classical soil mechanics and foundation engineering, and applies these principles to agricultural engineering situations. Theoretical design formulae are given, plus tables and graphs dealing with bearing capacity factors, wall pressure factors, soil cutting numbers and soil mechanical properties. Many example problems of design and analysis are solved in the text, and there are unsolved problems given for each chapter.The text begins with descriptions of soil origins and classification systems, including agricultural classification schemes, and then introduces classical concepts of soil strength and strength measurement techniques in the laboratory and in the field. Soil mechanics is applied to the design of shallow foundations, and the design formulae as well as tables of bearing capacity factors for design use are provided. New research and design findings in the specialized area of tall and heavy farm silos are also given, in addition to deep pile foundation design for heavy structures on very soft soils. Water flow in soils is treated, together with stability of ditch bank slopes and small earth dams, design of retaining walls and pressure pressures in bins and silos, soil erosion and protection methods, soil cutting and tillage design methods, soil compaction analysis, the use of geotextiles and problems of soil freezing.The book is directed primarily at professional university students in Agricultural Engineering, but will also be of interest to scientists working in other engineering branches, landscape architecture, soil physics and the like.

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