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Books in Life sciences

    • Neurobiology of Psychiatric Disorders

      • 1st Edition
      • Volume 106
      • June 26, 2012
      • Thomas E Schlaepfer + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 2 0 0 2 9
      • eBook
        9 7 8 0 4 4 4 5 3 5 0 0 9
      This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment.
    • Sleep and Brain Activity

      • 1st Edition
      • July 18, 2012
      • Marcos G. Frank
      • English
      • Hardback
        9 7 8 0 1 2 3 8 4 9 9 5 3
      • eBook
        9 7 8 0 1 2 3 8 4 9 9 6 0
      In the last few decades, scientists have discovered that far from being a time of neural silence, sleep is characterized by complex patterns of electrical, neurochemical, and metabolic activity in the brain. Sleep and the Brain presents some of the more dramatic developments in our understanding of brain activity in sleep. The book discusses what parts of the brain are active in sleep and how, and presents research on the function of sleep in memory, learning, and further brain development. Coverage encompasses the network and membrane mechanisms responsible for waking and sleeping brain activity, the roles of glial cells in the sleeping brain, the molecular basis of sleep EEG rhythms, and research on songbirds, rodents, and humans indicating the function of sleep.
    • Insect Pests of Potato

      • 1st Edition
      • August 8, 2012
      • Andrei Alyokhin
      • English
      • Hardback
        9 7 8 0 1 2 3 8 6 8 9 5 4
      • eBook
        9 7 8 0 1 2 3 8 6 8 9 6 1
      Insect Pests of Potato: Biology and Management provides a comprehensive source of up-to-date scientific information on the biology and management of insects attacking potato crops, with an international and expert cast of contributors providing its contents. This book presents a complete review of the scientific literature from the considerable research effort over the last 15 years, providing the necessary background information to the subject of studying the biology management of insect pests of potatoes, assessment of recent scientific advances, and a list of further readings. This comprehensive review will be of great benefit to a variety of scientists involved in potato research and production, as well as to those facing similar issues in other crop systems.
    • Genetics and Biotechnology of Bacilli, Volume 2

      • 1st Edition
      • December 2, 2012
      • A.T. Ganesan
      • English
      • Paperback
        9 7 8 0 1 2 3 9 5 9 9 4 2
      • eBook
        9 7 8 0 3 2 3 1 3 8 7 1 0
      Genetics and Biotechnology of Bacilli, Volume 2 is a collection of papers from the "Fourth International Conference on Bacilli" held in California on June 21-24, 1987. One paper reviews the results of cloning and characterization of genes for secreted enzyme and of genes that control the expression of secreted enzymes in relation with other prokaryotic regulatory systems. Other papers tackle the regulation of gene expression during sporulation, the sigma factors, bacterial toxins, and antibiotic resistance genes. One paper reports that three genes responsible for the code for peptides found in BT cuboidal crystals have been successfully cloned. The three codes have different toxic characteristics in relation to tobacco hornworm larvae or mosquito larvae. Other papers examine replication. Such examination pertains to the two levels of control on the chromosome involved in DNA replication, or to the possible functional importance that several membranes associated DNA subcomplexes can have in Bacillus subtilis, where one of these appear to control initiation. Other papers discus secretion and extracellular enzymes, as well as, the different genetic systems and methods. This collection can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology, microchemistry, or toxicology.
    • Planar Lipid Bilayers

      • 1st Edition
      • December 2, 2012
      • W. Hanke + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 3 2 2 9 9 5 3
      • eBook
        9 7 8 0 0 8 0 9 8 4 0 6 3
      Biological Techniques is a series of volumes aimed at introducing to a wide audience the latest advances in methodology. The pitfalls and problems of new techniques are given due consideration, as are those small but vital details not always explicit in the methods sections of journal papers.In recent years, most biological laboratories have been invaded by computers and a wealth of new DNA technology and this will be reflected in many of the titles appearing in the series.The books will be of value to advanced researchers and graduate students seeking to learn and apply new techniques, and will be useful to teachers of advanced undergraduate courses involving practical or project work.Methods of constructing artificial membranes (planar lipid bilayers) from the main components of cell membranes (lipids) date from the early 1960s.Planar bilayers offer direct, quantitative experimental approaches to the study of membranes of precisely determined composition which can be manipulated by the experimenter. Pore-forming molecules, transporter molecules, ATP-dependent enzymes and other entities can be incorporated into the bilayers to simulate biological functions.Reconstitu... of such functions in this way remains a key final step in attributing a functional role to purified cell membrane proteins.This book aims to demystify these techniques and begins with a broad overview of the development of the subject before dealing with the protocols involved.Key references are provided at the end of the book together with a list of suppliers.
    • Evolution of the Primate Brain

      • 1st Edition
      • Volume 195
      • January 25, 2012
      • English
      • Hardback
        9 7 8 0 4 4 4 5 3 8 6 0 4
      • Paperback
        9 7 8 0 4 4 4 6 0 2 2 7 5
      • eBook
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      This volume of Progress in Brain Research provides a synthetic source of information about state-of-the-art research that has important implications for the evolution of the brain and cognition in primates, including humans. This topic requires input from a variety of fields that are developing at an unprecedented pace: genetics, developmental neurobiology, comparative and functional neuroanatomy (at gross and microanatomical levels), quantitative neurobiology related to scaling factors that constrain brain organization and evolution, primate palaeontology (including paleoneurology), paleo-anthropology, comparative psychology, and behavioural evolutionary biology. Written by internationally-reno... scientists, this timely volume will be of wide interest to students, scholars, science journalists, and a variety of experts who are interested in keeping track of the discoveries that are rapidly emerging about the evolution of the brain and cognition.
    • Functional Neural Transplantation III

      • 1st Edition
      • Volume 201
      • December 13, 2012
      • English
      • Hardback
        9 7 8 0 4 4 4 5 9 5 4 4 7
      • eBook
        9 7 8 0 4 4 4 5 9 5 4 5 4
      This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.
    • The Role of Membranes in Metabolic Regulation

      • 1st Edition
      • December 2, 2012
      • Myron Mehlman
      • English
      The Role of Membranes in Metabolic Regulation is the second volume in a series of in-depth reviews of specific areas of metabolic regulation. This volume is based on the 1972 symposium on The Role of Membranes in Metabolic Regulation held at the University of Nebraska Medical School. Separating 20 manuscripts into chapters, this book emphasizes membrane structure and function as well as utilization of affinity chromatography for purification of biologically important cellular components, called membrane receptors. It also discusses the role of phospholipids in hormone sensitive enzyme systems, with an emphasis on adenylate cyclase system. Other chapters describe the induction of steroidogenesis by corticotrophin and its synthetic analogues coupled by an azo linkage in free adrenal cells and the interaction between the mammary epithelial cells and insulin-sepharose systems. Topics on erythrocyte as a system for studying the properties of adenylate cyclase and the ionic effects in the sugar transport regulation in muscle are discussed in the concluding chapters of the book. Biochemists, physiologists, pharmacologists, physicians, researchers, and all others interested in the concepts about metabolic regulation will find this series of great value.
    • Dictyostelium Discoideum

      • 1st Edition
      • December 2, 2012
      • William Loomis
      • English
      Dictyostelium Discoideum: A Developmental System presents D. discoideum as a model eukaryotic system to study a variety of developmental problems. The book describes the life cycle of the organism D. discoideum which exists in nature as a soil amoeba in forest detritus. The nuclei of D. discoideum contain DNA, RNA, and proteins which have properties similar to those of histones present in calf thymus nuclei. The unique sequences of the genome of the organism code for the gene products synthesize during its growth and development. One approach in genetic analyses to understanding the developmental processes of the organism is to isolate a large number of morphological mutants. The isolation process will indicate the number of variations that are open to the developing system, and will point to causal connections between stages. The text also explains that the number of cells which differentiate into stalk cells is the result of timing and mechanics of the process of culmination. Ashworth (1971) suggests that cells in pseudoplasmodia of D. discoideum adjust their positions in relation to the chemical structure of the sheath itself. A model shows how cells communicate their response to the sheath in an axial fashion. The book can prove beneficial for biochemists, micro-biologists, cellular researchers, and investigators involved in the study of cellular biology.
    • RNA and Protein Synthesis

      • 1st Edition
      • December 2, 2012
      • Kivie Moldave
      • English
      • Paperback
        9 7 8 0 1 2 5 0 4 1 8 0 5
      • eBook
        9 7 8 0 3 2 3 1 4 2 3 4 2
      RNA and Protein Synthesis is a compendium of articles dealing with the assay, characterization, isolation, or purification of various organelles, enzymes, nucleic acids, translational factors, and other components or reactions involved in protein synthesis. One paper describes the preparatory scale methods for the reversed-phase chromatography systems for transfer ribonucleic acids. Another paper discusses the determination of adenosine- and aminoacyl adenosine-terminated sRNA chains by ion-exclusion chromatography. One paper notes that the problems involved in preparing acetylaminoacyl-tRNA are similar to those found in peptidyl-tRNA synthesis, in particular, to the lability of the ester bond between the amino acid and the tRNA. Another paper explains a new method that will attach fluorescent dyes to cytidine residues in tRNA; it also notes the possible use of N-hydroxysuccinimide esters of dansylglycine and N-methylanthranilic acid in the described method. One paper explains the use of membrane filtration in the determination of apparent association constants for ribosomal protein-RNS complex formation. This collection is valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and investigators working with enzymes.