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Elsevier

Books in Life sciences

  • Hormones and the Fetus

    • 1st Edition
    • J. R. Pasqualini + 2 more
    • English
    Volume One of Hormones and the Fetus contained a generalization of the role of hormones during fetal life. In this second volume, the main topics focus on hormonal binding to fetal and maternal plasma proteins, amniotic fluid and placenta; the presence of hormone receptors in the fetal compartment; and the mechanism of action of various hormones in different target tissues of the fetus and placenta. This up-to-date information is of major importance in the study of hormonal activity in fetal life, and the biological effect of hormones through the receptor. The mechanism of fetal sexual differentiation, in which hormones play an important role, is extensively covered.

  • Oogenesis

    The Storage of Developmental Information
    • 1st Edition
    • Chr. P. Raven
    • G. A. Kerkut
    • English
    International Series of Monographs on Pure and Applied Biology, Volume 10: Oogenesis: The Storage of Developmental Information focuses on the processes, reactions, and transformations involved in oogenesis. The book first offers information on embryonic development as a communication problem, formation of the egg cells, and the egg nucleus during oogenesis. Topics include decoding of developmental information, egg membranes, oogenesis, phase of nuclear activity, cytochemistry of the nucleus, and the egg cell. The manuscript also ponders on the cytoplasm and its inclusions and the relationships between the egg cell and the auxiliary cells. The text elaborates on the metabolism of the oocyte, cortex, and polarity and symmetry. The book also examines the storage of developmental information and information theory and biology. Genotypical information, physical foundation of developmental biology, and information and finality are discussed. The manuscript is a dependable reference for readers interested in oogenesis.

  • Life Sciences and Space Research

    Proceedings of The Open Meetings of The Working Group on Space Biology of The Twentieth Plenary Meeting of COSPAR, Tel Aviv, Israel, 7-18 June 1977
    • 1st Edition
    • R. Holmquist + 1 more
    • English
    Cospar Life Sciences and Space Research, Volume XVI covers the proceedings of the Open Meetings of the Working Group on Space Biology of the 20th Plenary Meeting of COSPAR, held in Tel Aviv, Israel, on June 7-18, 1977. The book focuses on the developments in space explorations; approaches for the creation of extraterrestrial intelligence; and biochemical mechanism of the visual-light-flash phenomena. The selection first discusses the Viking Lander biology experiments on Mars. The experiments returned detailed picture of the Martian soil surface chemistry. The text also takes a look at a preliminary search for narrowband signals at microwave frequencies; observational program options and system requirements for the search of extraterrestrial intelligence; and public health considerations related to a Mars surface sample return mission. The book reviews planetary protection guidelines for outer planet missions, including Viking clean room technology, efficacy of clean room assembly, and Jupiter Orbiter Probe PP appraisal. The text also focuses on the effects of temperature, salinity, and other factors on the growth and formation of UV-absorbing substances by the fungus aspergillus; effects of gravitational and magnetic fields on transplanted neuroblastoma vascularity; and the roles of body mass and gravity in identifying the energy requirements of homoiotherms. The selection is a dependable reference for readers interested in space research.

  • Pharmaceutical and Biomedical Applications of Liquid Chromatography

    • 1st Edition
    • Volume 1
    • W.J. Lough + 2 more
    • English
    This volume reflects the changes that have taken place in the pharmaceutical industry over the last ten years, most notably the increased importance attached to the question of chirality, the growing influence of biotechnology and the need for more rigorous documentation and validation of analytical methods and procedures.The first part of this book deals with the application of new technology to pharmaceutical and biomedical analysis, reflecting the present needs for increased speed, sensitivity and selectivity in the analysis of drugs. The second chapter provides an overview of capillary electophoresis, which represents one of the most inportant analytical developments to impact directly on pharmaceutical development in recent years. Although not a chromatographic technique, capillary electrophoresis was considered too important to be ignored.Over the last 25 years, liquid chromatography has grown into a mature analytical technique and many of the fundamental issues concerned with retention and separation are well defined. The practitioners of modern liquid chromatography spend as much time in the development of techniques for sampling handling and automation as they do in the development of the separation. Therefore, Part Two of this book describes some of the recent advances in the areas of sample handling and the isolation of compounds from biological samples, including solid phase extraction, restricted access media for direct injection, coupled column technology and microdialysis. Similarily, Part Three contains two chapters concerned with liquid chromatographic methods for the isolation of drug substances, peptides and proteins from other complex media.The pharmaceutical industry and the process of drug development are highly regulated and the increasing importance that the regulatory authorities attach to validation has had a significant impact on the analytical techniques used for the analysis of drugs. Although this has increased the workload of analysts in the pharmaceutical industry, it has also improved the quality of analytical methods used in the support of investigational and new drug applications as well as the quality of methods published more recently in the literature. Consequently, Part Four of this volume describes approaches to the optimization and validation of liquid chromatography methods for the analysis of drugs in the bulk form, in pharmaceutical formulations and biological fluids.

  • Chemistry and Analysis of Hop and Beer Bitter Acids

    • 1st Edition
    • Volume 27
    • M. Verzele + 1 more
    • English
    Largely based on laboratory work, the volume opens with a review on hops in general, while the bulk of the book covers the chemistry of the bitter acids of hop and beer. Practical, fully detailed procedures on the preparation and/or the separation of many of the compounds discussed are included. There is a chapter included on the complicated issue of bitter acid analysis, and several on the high-efficiency liquid chromatography of hop bitter acids.Bearing in mind the lack of literature produced recently in this field, the book is an excellent review of the present state of knowledge, and gives a large list of topics pointing to worthwhile studies for the future. The indexes provided will serve as a reference library-dictionary to hops, hop and beer bitter acids chemistry and analysis.

  • Photosynthetic Reaction Center

    • 1st Edition
    • Volume 2
    • Johann Deisenhofer + 1 more
    • English
    The availability of the photosynthetic reaction center's structure at an atomic resolution of less than three angstroms has revolutionized research. This protein is the first integral membrane protein whose structure has been determined with such precision. Each volume of the Photosynthetic Reaction Center contains original research, methods, and reviews. Together, these volumes cover our current understanding of how photosynthesis converts light energy into stored chemical energy.Volume II details the electron transfer process; it is oriented to the physical aspects of photosynthesis. It thus primarily discusses bacterial photosynthesis and model compounds. Volume II features the very complex and rapidly evolving issues associated with the theory of electron transfer in the bacterial reaction center, and explores picosecond and femtosecond spectroscopy. This volume also covers holeburning spectroscopy; primary events of bacterial photosynthesis with emphasis on the application of large, external electric fields designed to manipulate and probe mechanisms of the initial chemistry; the role of accessory carotenoid pigments; the techniques of infrared spectroscopy and magnetic resonance as applied to photosynthesis; and the interplay between natural and artificial photosynthesis.

  • Neuropathology

    Brussels, 21-28 July 1957
    • 1st Edition
    • L. Van Bogaert + 1 more
    • English
    Neuropathology, Volume IV presents the proceedings of the First International Congress of Neurological Sciences, held in Brussels, Belgium, on July 21–28, 1957. This book provides information pertinent to the fundamental aspects of neuropathology. Organized into 84 chapters, this compilation of papers begins with an overview of the problem of multiple sclerosis and its relationship to leucodystrophies. This text then explains the two major histopathological manifestations of the injury caused by the rabies virus in the central nervous system. Other chapters consider the successful identification and isolation of a biologically active compound, which depends to a large extent on the availability of a quantitative bioassay. This book discusses as well the clinical manifestations, pathogenesis, and treatment of multiple sclerosis. The final chapter deals with the study of nucleic acids as well as histochemistry as a method of histological inquiry. This book is a valuable resource for neuropsychiatrists, biochemists, physicians, and scientists.

  • Pulsatility in Neuroendocrine Systems

    • 1st Edition
    • Volume 20
    • P. Michael Conn + 1 more
    • English
    Pulsatility is now recognized as a nearly ubiquitous functional feature of neuroendocrine systems. This volume presents a comprehensive guide to the established and emerging technologies being used to study the perplexing phenomenon of pulsatility. Molecular, cellular, physiological, and mathematical approaches are described in detail.

  • Cognitive Development

    The Child's Acquisition of Diagonality
    • 1st Edition
    • David R. Olson
    • David S. Palermo
    • English
    Cognitive Development: The Child's Acquisition of Diagonality is an empirical and rational enquiry into the child's development of a conceptual system relating to the concept of the diagonal during the age range three to six years. A detailed examination will be made of why a young child has difficulty with such a problem, and what occurs during development that removes this difficulty. In the context of these empirical arguments, the book considers such theoretical questions as the nature of intellectual skills and conceptual or symbolic knowledge, as well as the role of experience and instruction in their development. The study concludes with a description of the child's reconstruction of the diagonal in terms of what at least poses as a general model of perceptual and intellectual development, and accounts for, among other things, man's increasing ability to apprehend and theorize about the motion of the stars. It shows that it is the elaboration of the child's perceptual knowledge in the context of his performatory attempts in such cultural media as language and geometry that accounts for his ability to copy a diagonal in particular and his intellectual development in general.

  • Pathobiology of Cell Membranes

    Volume I
    • 1st Edition
    • Benjamin F. Trump + 1 more
    • English
    Pathobiology of Cell Membranes, Volume I, represents the first in a multivolume treatise designed for pathologists and cell biologists interested in the role of membrane alterations in disease processes. The treatise will emphasize concepts related to membrane alterations in cell injury as well as methods for elucidating such changes. The book begins with a discussion of the general conceptual aspects of cell injury and some details about the role of membrane alterations in the pathogenesis of both lethal and sublethal cellular reactions. This is followed by separate chapters on applications of circular dichroism to the study of membranes; a cell injury mechanism involving membrane components at the molecular level; and fundamental aspects of cell volume regulation and the modification of this regulation by primary or secondary damage of the cell membrane. Subsequent chapters deal with comparative roles of lysosomal and other membrane damage in cell injury; the role of membrane movements and various types of lysosome formation; toxic effects on mitochondrial membranes; and the concept of a biological membrane in health and disease at the tissue level.

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