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Books in Life sciences

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    • Epigenetic Mechanisms in Brain Physiology and Disorders

      • 1st Edition
      • Moshe Szyf + 1 more
      • English
      Epigenetic Mechanisms in Brain Physiology and Disorders provides a comprehensive summary of epigenetic mechanisms in brain development, from embryogenesis to aging, brain physiology and pathology. It discusses the role DNA methylation plays in regulating genomic functions, which in turn guide brain function. The book explores the epigenetic role in cell type differentiation, epigenetic processes in memory, learning, and neuronal functioning, the role of DNA methylation and other epigenetic mechanisms in sleep, feeding and metabolic control, sex, temperature regulation, and cardiovascular and blood pressure regulation. It further explores the role of epigenetic processes in neuropsychiatry disorders, neurological disease and behavioral disorders, as well as epigenetic diagnostics and therapeutics.

    • Pharmaceutical QbD with Design of Experiments

      Statistical Tools and Applications in Drug Delivery Systems
      • 1st Edition
      • Khushwant Yadav
      • English
      Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment.Researcher... in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

    • Advances in Immunology

      • 1st Edition
      • Volume 168
      • English
      Advances in Immunology, Volume 168, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Sample topics in this new release include Alarmins in mucosal tissues and how they regulate health and disease, and more.

    • Deep Learning Applications in Neuroinformatics

      Advances, Methods, and Perspectives
      • 1st Edition
      • Karthik Ramamurthy
      • English
      Deep Learning Applications in Neuroinformatics: Advances, Methods, and Perspectives explores how deep learning revolutionizes neuroinformatics, covering the latest methods and applications of deep learning in analyzing neuroimaging data from EEG, MRI, PET, and more. The book addresses critical neurological disorders like Alzheimer’s disease, Mild Cognitive Impairment, Stroke, and Autism Spectrum Disorder, bridging the gap between neuroscience and artificial intelligence. It is an ideal resource for researchers, practitioners, and students with insights from leading experts.

    • Fundamentals of Molecular Structural Biology

      • 2nd Edition
      • Subrata Pal
      • English
      Fundamentals of Molecular Structural Biology, Second Edition reviews the mathematical and physical foundations of molecular structural biology, covering the latest advancements. The book begins with historical perspectives before exploring mathematical concepts, physical aspects of chemistry, the chemical basis of biology, structural analysis, visualization, protein folding, transcription, RNA processing, cell signaling, and computational molecular biology. Additionally, this new edition delves into AI fundamentals and applications, including AlphaFold and RoseTTAFold. This fully updated edition provides a detailed overview of the fundamental concepts across molecular structural biology and acts as an ideal guide for researchers and advanced students.Given the increasingly interdisciplinary nature of this subject, this book provides early career researchers and those shifting into an adjacent field a "fundamentals" resource to get them up-to-speed on the foundations of a particular field.

    • Nanotherapeutics for Treating Neurodegenerative Disorders

      • 1st Edition
      • Manish K. Chourasia + 3 more
      • English
      Nanotherapeutics for Treating Neurodegenerative Disorders reviews the complex landscape of neurodegenerative disorders, outlining the nuances of treatment strategies and the imperative role of nanotechnology in revolutionizing therapeutic interventions. From explaining the transport mechanisms of the Blood-Brain Barrier to unveiling the therapeutic potential of stem cell-derived nanocarriers, each chapter offers invaluable insights into the diverse array of nanotherapeutic approaches helping to reshape the landscape of neurological healthcare. By consolidating current updates on advanced targets-based nanotherapeutics, this book provides a comprehensive resource for neurodegenerative diseases converge.Whether seeking to unravel the complexities of mitochondrial dysfunction or to harness the potential of nanocarriers for targeted genetic material delivery, readers will find themselves equipped with the tools to navigate the forefront of neurotherapeutic innovation.

    • Microplastics and the Hidden Threat to Human Reproduction

      Plastic Peril
      • 1st Edition
      • Nimra Afzal + 1 more
      • English
      Microplastics and the Hidden Threat to Human Reproduction: Plastic Peril explores the intricate relationship between microplastics and reproductive health, delving into the sources and distribution of microplastics in the environment, human exposure routes, associated risks, the toxicological effects on reproductive health, potential connections to fertility, endocrine disruption, and developmental consequences due to maternal exposure. It includes impacts on both male and female reproductive health, risks during pregnancy, population-level health concerns, strategies for mitigating microplastic exposure, and the policy and regulatory frameworks surrounding this issue. The book also provides insights into the future direction of research and public health initiatives.In essence, it explores how tiny microplastic particles can have significant and far-reaching consequences on human reproductive health, making this a vital and emerging area of concern. This is a comprehensive resource for anyone interested in understanding the various aspects of the microplastics-reprod... health connection and a go-to reference for researchers, healthcare professionals, policymakers, and concerned individuals.

    • Immunomodulators

      • 1st Edition
      • Volume 151
      • English
      Immodulators, Volume 151 explores the pivotal role immodulators play in regulating immune responses for health and disease management. The book provides an in-depth overview of various classes of immunomodulatory agents, including biologics, small molecules, natural compounds, and synthetic drugs, examining their mechanisms of action and therapeutic applications. Chapters in this new release include Marine-Derived Polysaccharides and Peptides as Next-Generation Immunomodulators: Molecular Mechanisms, Therapeutic Potential, and Translational Challenges, Advances in Immunomodulation: From Dietary Influence to Computational Precision, iPSC-derived immunotherapy for Tau and Alzheimer's disease, and much more.Additional sections cover Antibodies targeting amyloid-β and Tau oligomers in Alzheimer's Disease, Biosimilars: Antibody and Nanobody Based Therapeutic Approaches Towards Protein Misfolding Diseases, Immunomodulator drugs: mechanisms of action and systemic effects, Microbiome and microbial products as immunomodulators: implication for gastrointestinal cancers, Integration of Network pharmacology, docking, and dynamics analysis to investigate the immunomodulatory activity of Pongamia pinnata, Transcriptomic Insights into Epigenetic and Immunomodulatory Roles of Nuclear Histone Genes in Bladder Cancer: A bioinformatics Approach, Utilizing DREIMT Database for Drug Prioritization in Immunomodulatory Therapy for Psoriasis and Psoriatic Arthritis, and many additional topics.

    • Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures

      • 1st Edition
      • Manuel Herrero Trujillano + 4 more
      • English
      Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures ameliorates the dearth of literature covering interventional pain procedures under both X-ray and ultrasound guidance. While existing resources focus on either modality separately, this book fills the gap by providing a consolidated approach, leveraging the strengths of both techniques. By doing so, it ensures practitioners have access to the most versatile and effective imaging methods available. This book is inherently practical, designed to serve as a go-to guide for clinicians facing real-world challenges in pain management. Its organization by body areas facilitates quick access to relevant techniques, while step-by-step guidance and visual aids ensure clarity and ease of understanding. By focusing on clinical relevance, the book empowers practitioners to implement evidence-based imaging interventions with confidence and precision. Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures has the potential to make a meaningful impact on the field of pain management. By equipping practitioners with cutting-edge imaging techniques and insights, it promises to improve patient outcomes and advance the standard of care. Moreover, its global reach ensures that its benefits extend far beyond geographical boundaries, reaching pain medicine practitioners worldwide.

    • Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology

      • 1st Edition
      • Swagat Kumar Das + 2 more
      • English
      Emerging Trends and Imminent Applications in Immunology and Pharmaceutical Biotechnology delves into historical perspectives, current trends, and future projections for research and development of immunological and biopharmaceutical products. Sections explore immunostimulants, natural and synthetic immunostimulants in aquaculture and animal husbandry, immunomodulators, immune boosters, pre- and probiotics in health promotion, cutting-edge immunological techniques for disease diagnosis, immunotherapy in cancer treatment, and transplantation immunology. Following chapters explore the impact on pharmaceutical biotechnology, with discussions on traditional and modern approaches in drug delivery, in silico drug delivery modeling, biocomposites and their pharmaceutical applications, recent advances in monoclonal antibodies production, vaccine development, and much more.Finally, the book covers the pivotal role of AI, machine learning, and data analytics in the clinical study of immunotherapy and pharmaceutical drugs, thus paving the way for enhanced research and development efficiency. Researchers in industry and academia alike will gain valuable insights into the novel principles behind designing and developing immunological and drug products, making this title an essential resource.

Related subjects

Agricultural and biological sciences

Drug discovery

Immunology

Microbiology and virology

Neuroscience

Pharmaceutical sciences

Pharmacology

Toxicology