Life sciences print books and ebooks | Elsevier

Neurotoxins

1st Edition
Volume 8
October 22, 2013
P. Michael Conn
English
eBook
9 7 8 1 4 8 3 2 8 4 8 8 0

The exquisite simplicity and potency of toxins have made them valuable probes of neural systems. This book presents a comprehensive compilation of techniques used for the preparation, handling, and, particularly, for the use of neurotoxins. Model systems are described in which these neurotoxins have been extremely valuable in developing an understanding of the cellular and molecular basis of secretion and electrophysiological events leading to altered cell function.

Comprehensive Insect Physiology, Volume 10

1st Edition
October 22, 2013
G. A. Kerkut
English
eBook
9 7 8 1 4 8 3 2 8 6 2 2 8

The underlying theme of this volume is the understanding of the molecules and processes important in the primary metabolism of insects. The 19 chapters provide both rich historical perspectives and timely reviews of current research, as well as showing the extent of progress to be expected in the near future, including the application of advanced techniques now used for the study of microbial and mammalian processes. The major themes of metabolism, proteins and nucleic acids, and biochemical events in the nervous system each have several chapters devoted to them, but specific topics such as pigments, toxins, and aging are also covered in detail. This extensive volume is therefore an invaluable source of information not only for entomologists but also for all scientists whose work involves insect biochemistry, including zoologists, biochemists, and molecular biologists and geneticists.

Drug Design

1st Edition
October 22, 2013
E. J. Ariëns
English
Paperback
9 7 8 1 4 8 3 2 0 2 6 5 5
eBook
9 7 8 1 4 8 3 2 1 6 0 8 9

Drug Design, Volume VI covers practical approaches to the development of bioactive compounds, with focus on antiradiation agents, organ-imaging radiopharmaceuticals... X-ray contrast media, proteinase inhibitors, and pesticide formulations. The book discusses the chemical routes available for the synthesis of diphenhydramine derivatives, the biological activities, the relationships between structure and activity, and the phase of manipulation in the design of diphenhydramine derivatives. The text also describes the design of antiradiation agents, organ-imaging radiopharmaceuticals... and X-ray contrast media, as well as the rational approach to proteinase inhibitors. The chemical and physical methods of formulation of agricultural pesticides are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design and manufacture will find the book invaluable.

Advances in Drug Research

1st Edition
Volume 22
October 22, 2013
Bernard Testa
English
Hardback
9 7 8 0 1 2 0 1 3 3 2 2 2
Paperback
9 7 8 1 4 8 3 2 3 4 9 4 6
eBook
9 7 8 1 4 8 3 2 6 6 8 9 3

Advances in Drug Research, Volume 22 focuses on the concepts and facts of drug research. This book is divided into four chapters. Chapter 1 discusses the use of atomic properties and atom-centered indices in QSAR models, while Chapter 2 describes the pharmacokinetics of peptides and proteins. The nuclear receptors, emphasizing the aspects of molecular and genomic pharmacology are elaborated in Chapter 3. The last chapter covers the medicinal chemistry of a vast group of agents acting on nuclear receptors. This publication is valuable to drug researchers and students interested in advances in drugs.

International Review of Connective Tissue Research

1st Edition
October 22, 2013
M. A. Epstein
English
eBook
9 7 8 1 4 8 3 1 9 4 9 9 8

International Review of Connective Tissue Research, Volume 2 is a collection of papers that deals with the morphological background, physiological, and pathological aspects of studies done on connective tissues. One paper discusses the precipitation of collagen fibers from solution — that fibrils form in vitro and in vivo by similar mechanisms. Another paper examines the importance of elastic tissues in the reactions of connective tissue including diseases of the vascular and pulmonary systems. As simple as elastic tissues appear to be, these can be models in studies of the basic structure and function of other more complicated tissues. One author discusses the physiology of the connective tissues of the reproductive tract; he concludes that defects in the connective tissue functions can cause failure in ovulation or the formation of cystic ovaries. Other authors discuss the diseases of collagen and related tissues (rheumatic fever, rheumatoid arthritis, systemic lupus erythematous, osteoarthritis, osteoporosis), as well as the aging process. One author analyzes the role of collagen fibers in aging: whether factors exist that causes cross-linking or ester cross-links or the dissolution of the collagen macromolecule associated with the aging of collagen. This book can prove helpful for molecular or cellular biologists, pathologists, physiologists, gerontologists, and researchers in gene therapy, pharmacology or micro-chemistry.

Herbicide Resistance in Weeds and Crops

1st Edition
October 22, 2013
J. C. Caseley + 2 more
English
Paperback
9 7 8 1 4 8 3 1 0 6 4 3 4
eBook
9 7 8 1 4 8 3 1 0 0 0 9 8

Herbicide Resistance in Weeds and Crops is a collection of papers presented at the 11th Long Ashton International Symposium in September 1989. The said symposium is held to study about the increasing incidence of herbicide-resistant weeds and the consideration of the production of herbicide-resistant crops. The book includes studies that suggest the delay and prevention of herbicide resistance; the gravity of the infestation of different herbicide-resistant weed; the management of herbicide resistance; and the mechanisms of herbicide tolerance. Also covered in the book are the improvement of different herbicides, as well as the prospective development of genetically engineered herbicide-resistant plants. Botanists, biochemists, and farmers would greatly benefit from the text, especially those who would like to explore and study the phenomenon.

Progress in Theoretical Biology

1st Edition
October 22, 2013
Robert J. Rosen + 1 more
English
Hardback
9 7 8 0 1 2 5 4 3 1 0 5 7
Paperback
9 7 8 1 4 8 3 2 0 5 8 6 1
eBook
9 7 8 1 4 8 3 2 1 9 2 9 5

Progress in Theoretical Biology, Volume 5 covers the developments in theoretical biology. The book discusses the dynamic behaviors exhibited by cellular control circuits and the role of the cell as a morphogenetic and physiological unit; the stable dynamics of genetic networks; and the organization principles and models of the function of the simplest genetic systems controlling ontogenesis. The text also describes the conceptual framework shifts in immunogenetics: the anatomy of the Ag system; the basic problems of memory in behavioural and developmental biology; and the self-organization and performance of sensory-motor codes, maps, and plans. Physiologists, biophysicists, geneticists, mathematicians, and cytologists will find the book useful.

Manipulation of Fruiting

1st Edition
October 22, 2013
C. J. Wright
English
Paperback
9 7 8 1 4 8 3 1 3 2 0 4 4
Hardback
9 7 8 0 4 0 8 0 2 6 0 8 6
eBook
9 7 8 1 4 8 3 1 6 4 4 6 5

Manipulation of Fruiting contains the proceedings of the 47th University of Nottingham Easter School in Agricultural Science, held at Sutton Bonington, England on April 18-22, 1988. The papers explore developments in the manipulation of fruiting and cover topics ranging from intra-plant competition to pollination, fruit set, and light interception and canopy manipulation. Genetic regulation and chemical manipulation of fruiting are also discussed. This monograph is comprised of 26 chapters divided into nine sections. The first section deals with the interactions that occur between vegetative and reproductive growth, focusing on source-sink effects and dry matter partitioning. The following three sections examine the sequential stages of producing a fruit from flower initiation, dormancy, and anthesis, through pollination to fruit set. Models that describe dormancy and flowering are presented; pollen incompatibility is considered; and the time available for pollination is analyzed. The physiology of fruit set is discussed together with methods to improve fruit set. The next three sections detail methods of manipulating fruiting, either physically by altering plant canopy structure and therefore light interception, genetically by breeding and selection, or chemically by the use of plant growth regulators. This book concludes with a look towards the future using genetic manipulation to alter fruit physiology. This text will be a valuable resource for crop researchers, plant physiologists, geneticists, and others interested in the state of research into fruiting.

Pharmacology of Histamine Receptors

1st Edition
October 22, 2013
C. R. Ganellin + 1 more
English
Paperback
9 7 8 1 4 8 3 1 7 7 6 0 1
eBook
9 7 8 1 4 8 3 1 9 3 4 1 0

Pharmacology of Histamine Receptors presents a summary of the pharmacology of histamine receptors. It discusses the research and developments made in the use of histamine. It addresses the biological actions of the drug in various pathological instances. Some of the topics covered in the book are the classification of histamine receptors; mepyramine and related histamine antagonists; activity relationships of drugs acting at histamine receptors; chemical structure of histamine; effects of methyl substituents in histamine; enzymes involved in histamine metabolism; and histamine in body fluids. The cellular sources of histamine in tissues and blood are fully covered. The relationship of the mast cell to basophil is discussed in detail. The text describes in depth the urinary excretion of histamine and metabolites. The pathological conditions in man are presented completely. A chapter is devoted to the fundamental properties of adenylate cyclase and its measurement. The book can provide useful information to pharmacists, doctors, chemists, students, and researchers.

Energy Metabolism

1st Edition
October 22, 2013
Laurence E. Mount
English
Hardback
9 7 8 0 4 0 8 1 0 6 4 1 2
eBook
9 7 8 1 4 8 3 1 6 1 7 9 2

Studies in the Agricultural and Food Sciences: Energy Metabolism is a compilation of works on the energy metabolism in animals, especially animals of agricultural importance. The book is written by authoritative workers in the field and is divided into six parts; each chapter is based on a selected paper presented at the Eighth Symposium on Energy Metabolism held at Cambridge in September 1979. The text discusses feed evaluation; use of energy for maintenance and growth; and simulation models for energy exchange and growth. The book also covers the comparative aspects of energy metabolism; use of energy in production and lactation; and metabolic responses in the growing animal. The monograph is recommended for those who plan to study about energy metabolism of farm animals and its relationship with certain biological processes. The book will also appeal to those who develop feeds and methods that can help improve energy metabolism of farm animals.

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