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Elsevier

Books in Life sciences

  • New Trends in Methodological Approaches for Fish Biology

    • 1st Edition
    • Ignacio Fernandez Monzón + 1 more
    • English
    New Trends in Methodological Approaches for Fish Biology provides an extensive guide on the novel tools and methodologies that are available to fish biologists across diverse sectors. The book combines a historical overview of each research area with detailed descriptions of emerging cellular and molecular tools. Sections explore recent advances in fish genomics, nutrition, development, reproduction, health, and welfare. Given the breadth of subject matter, this is an essential resource for students, academic researchers, aquaculturists and fisheries biologists, and resource managers alike. Written by a globally diverse team of experts, it is systematically structured for easy navigation by technical and nontechnical audiences. As research in this area is growing exponentially, reflecting the global economic significance of fisheries and aquaculture industries, fish as model research organisms, and aquatic ecosystem health, this book is a welcomed resource.

  • Bioactive Compounds

    Mechanisms, Challenges and Strategies for Bioaccessibility and Bioavailability
    • 1st Edition
    • Cristobal Noe Aguilar + 3 more
    • English
    Bioactive Compounds: Mechanisms, Challenges and Strategies for Bioaccessibility and Bioavailability brings together leading experts from the fields of nutrition, food science, and pharmacology to elucidate the intricate dynamics of bioactive compounds and their impact on human health. This comprehensive volume delineates the crucial differences between bioaccessibility and bioavailability, providing insight into their implications for health outcomes. Readers will explore the behavior of key classes of bioactive compounds, including polyphenols, carotenoids, and peptides, as well as their sources and interactions within the food matrix. The book further examines the essential role of gut microbiota in the absorption processes, highlighting how these interactions can influence bioactive compound efficacy in the human body. Bioactive Compounds: Mechanisms, Challenges and Strategies for Bioaccessibility and Bioavailability not only discusses the mechanisms of absorption, distribution, metabolism, and excretion (ADME) of bioactive compounds but also introduces cutting-edge tools and strategies designed to enhance their bioaccessibility and bioavailability. Chapters dedicated to innovative approaches, such as microfluidics and nanotechnology, provide practical insights into the development of effective delivery systems. With a focus on real-world applications and clinical implications, this book serves as a vital resource for academics, clinicians, food chemists, and nutritionists aiming to bridge the gap between research and application in the fields of nutraceuticals and functional foods while optimizing health outcomes.

  • The Safety Aspects of Food Waste Valorization

    Maintaining Quality Assurance in Resource Recovery
    • 1st Edition
    • Sidonia Martínez Suárez + 1 more
    • English
    The Safety Aspects of Food Waste Valorization: Maintaining Quality Assurance in Resource Recovery highlights the importance of safe food waste practices and strategies to effectively transform waste into valuable resources. Co-edited by two female authors with many global, female contributors represented, the book looks at the environmental consequences of food waste and its impact on human health. It details the risks associated with the use of food waste, analyzes food safety in valorized agri-food by-products, with a focus on mycotoxins, and demonstrates how to minimize safety risks from a variety of industries, including date-palm industrialization, wine, produce, cattle, olive oil and dairy. Finally, the book provides practical business strategies for bioactive ingredients derived from food by-products and details the recovery of food waste from an environmental and economic perspective.

  • Roles of the Cerebellum in Motor Control

    Foundations, Experimental Approaches and Clinical Applications
    • 1st Edition
    • Mario Manto + 2 more
    • English
    Roles of the Cerebellum in Motor Control: Foundations, Experimental Approaches and Clinical Applications is a groundbreaking, comprehensive reference on the intricate relationship between the cerebellum and motor function. Spanning five thorough sections, this book examines experimental approaches, from single neurons to networks, unraveling the mysteries of olivocerebellar somatotopy, motor prediction, and the cellular basis of motor learning. With chapters dedicated to neuroimaging, physiology, and pathophysiology, users will gain insight into the cerebellum's role in conditions such as tremor, dystonia, and Parkinson’s disease.From wearable sensors to digital gait biomarkers, various chapters offer a cutting-edge look at sensor technology and its application in assessing cerebellar function and rehabilitation. The book concludes with a discussion on research and clinical implications, providing a roadmap for translating laboratory findings into effective therapeutic strategies, making it an indispensable resource for researchers, clinicians, and students alike.

  • Social Determinants of Health in Surgery

    Research Methods and Clinical Review
    • 1st Edition
    • Steven A. Toms + 4 more
    • English
    Social Determinants of Health in Surgery: Research Methods and Clinical Review is a groundbreaking resource dedicated to examining the role of social determinants within surgical care. This book is designed for surgical trainees, healthcare providers, researchers, and policy administrators, offering a thorough exploration of how social factors impact surgical outcomes and practice. Featuring a detailed analysis of eleven key domains, it addresses the challenges and opportunities of integrating social determinants into surgical research and practice. The text provides essential guidance for those seeking to understand and improve patient outcomes through a broader, community-driven lens.In addition to its comprehensive coverage, the book delves into specialized topics such as big data analytics, ethical considerations, global health perspectives, pediatric surgical care, and clinical applications for research. It presents methodological guidance, including valuable tips and common pitfalls useful for readers at any stage of their surgical careers. The book also offers an in-depth review of social determinants research across ten major surgical specialties, highlighting significant trends, key studies, and current gaps in knowledge. Case studies and reflective interviews from experienced clinicians further enrich the reader’s understanding.

  • Tourette Syndrome and Other Tic Disorders

    • 1st Edition
    • Mariam Hull
    • English
    The Neuroscience of Tourette's Syndrome and Other Tic Disorders provides a foundation of the latest research into tic disorders and the brain, as well as including a comprehensive framework for the evaluation of tics. Authors across multiple specialties present the most thorough and latest knowledge of Tourette syndrome to include underlying pathophysiology, clinical presentation, how to differentiate it from other tic disorders, particularly functional tics. Clinical case studies will also feature throughout to outline challenging cases with expert commentary on evaluation and management strategies.

  • Introduction to Structural Bioinformatics

    • 1st Edition
    • Yang Zhang + 2 more
    • English
    Introduction to Structural Bioinformatics offers a complete overview on the fundamental concepts and methodologies of structural bioinformatics and computational structural biology. The book is divided into three sections, beginning with a discussion of the key principles of bioinformatics and fundamental aspects, including bioinformatics databases, multiple sequence alignment, and machine learning. Section two then moves on to structural bioinformatics, where topics include Monte Carlo simulation, protein structure prediction, RNA structure prediction, and protein design. The final section of the book focuses on experimental structural determination, where chapters focus on techniques including X-ray crystallography, nuclear magnetic resonance and cryo-electron microscopy. This is an ideal guide on key principles, methods, and the most up-to-date developments across structural bioinformatics and computational structural biology. It will be a comprehensive reference for postgraduate students, instructors, and researchers working in these and adjacent subjects.

  • The Human Nervous System

    • 4th Edition
    • George Paxinos + 2 more
    • English
    The 4th Edition of the classic book The Human Nervous System continues to assemble contributions from world leaders in research on the brain, spinal cord and peripheral nervous system. This book has been edited by the best-known team of brain cartographers, and it has been completely revised to present the cutting edge of human neuroscience. The structure, connections and function are explained in depth, making this book essential to any student or scientist interested in brain anatomy and function.

  • Lysosomal Pathophysiology of Parkinson’s Disease

    • 1st Edition
    • Mattia Volta + 1 more
    • English
    Lysosomal Pathophysiology of Parkinson’s Disease delves into the genetic and genomic revelations that have transformed our understanding of Parkinson’s Disease at the molecular level. The book highlights the critical role of the autophagy-lysosome pathway in the disease's pathogenic processes, drawing a comprehensive timeline of disease onset and progression. It offers a detailed examination of how disruptions in this pathway contribute to the hallmarks of Parkinson’s Disease, providing invaluable insights for researchers and clinicians alike. Subsequent chapters extend these insights by comparing Parkinson’s Disease to other neurodegenerative disorders such as Alzheimer’s Disease and Frontotemporal Dementia. By exploring protein pathology and synaptic alterations, the book underscores the broader implications of autophagy-lysosome dysfunction. Additionally, it discusses how the molecular perspectives gleaned from Parkinson’s Disease can inform our understanding of these other conditions, presenting a unified approach to studying neurodegeneration.

  • Fermented Foods for Wellness

    Understanding Processes and Biosensors
    • 1st Edition
    • Muhammad Shahzad Aslam + 2 more
    • English
    Fermented Foods for Wellness: Understanding Processes and Biosensors delves into the beneficial impact of fermented foods on reducing chronic inflammation, which is linked to numerous diseases. The book comprehensively explores how fermented foods like miso, kefir, and turmeric can enhance bioavailability and promote an anti-inflammatory response in the body. By examining the role of inflammation in various health conditions such as Inflammatory Bowel Disease and arthritis, the book provides valuable insights into the relationship between diet and health.The second section, titled The Industrial Fermentation Process, discusses how biosensor technology deciphers complex flavor compounds in fermented foods. It highlights sustainable fermentation practices and their transformative impact on various industries. The book underscores the importance of optimizing bioreactors to create ideal conditions for microbial growth, thus paving the way for future product development. By combining scientific research with practical applications, this book serves as an essential guide for understanding the intersection of nutrition, health, and industrial processes.

  • Virtual Possibilities

    Extended Reality as Assistive Technology for Inclusive Care
    • 1st Edition
    • Samiya Khan
    • English
    Virtual Possibilities: Extended Reality as Assistive Technology for Inclusive Care provides invaluable insights for researchers and related medical professionals into the transformative potential of virtual reality as a technological aid. The book navigates through the diverse applications of virtual reality in healthcare, transcending traditional uses such as medical training and therapeutic interventions. It is a dedicated examination of virtual reality's role in social care, addressing the unique needs of individuals across the spectrum, from differently abled individuals and children with learning disabilities to those grappling with disorders, trauma, and the elderly. It presents the state-of-the-art in this field, acting as a bridge, facilitating the translation of theory into practice and fostering ongoing research. Users will find this to be a valuable resource for researchers, professionals, and policymakers interested in the future applications of virtual reality in healthcare and social care.

  • Big Data Analytics in Agriculture

    Algorithms and Applications
    • 1st Edition
    • Manish K. Pandey + 3 more
    • English
    Big Data Analytics in Agriculture focuses on the quantitative and qualitative assessment of agricultural systems using state‑of‑the‑art technologies to deliver practical improvements in agricultural production.Addressin... the challenge of translating data into real‑world applications, the book provides a comprehensive mapping of the entire data lifecycle—from data generation, storage, and curation to processing and implementation. It guides readers through the steps required to produce high‑quality, reliable information that supports effective decision‑making. Following a logical progression, the volume demonstrates how diverse data streams converge into decision‑support systems and how they can be transformed into actionable outcomes, aligned with intelligent, efficient, technologically advanced, economically viable, and politically and culturally sustainable practices.The book further explores the integration of information and communication technologies (ICT) and the Internet of Things (IoT) for managing rural assets and enhancing economic and environmental performance in spatially and temporally variable agricultural environments. Topics covered include big data analytics, data management and processing, and a range of algorithms and applications relevant to agriculture. Subtopics encompass artificial intelligence‑ and machine‑learning‑ena... smart and precision irrigation, disease and pest management, microclimatic forecasting, preventive fertigation and chemigation, data‑driven smart farming through the Internet of Everything (IoE), and supply‑chain analytics for improved farm‑level operations.

  • Legal Issues in Quality for Healthcare Institutions

    • 1st Edition
    • Ramesh Sachdeva
    • English
    Legal Issues in Quality for Healthcare Institutions provides the perspective of practicing physicians, lawyers, and academic legal scholars to comprehensively address the implications for quality of care and patient safety both from a legal, medical, and improvement science standpoint. Hospital administrators, physicians, nurses, researchers, legal scholars, as well as regulatory and compliance officers working in hospitals and acute care facilities will find this to be a helpful resource in understanding and addressing the many facets and issues in the field of medicine and law related to quality and patient safety.

  • Alternative Splicing

    Recent Advances in Health and Disease
    • 1st Edition
    • Sayeed ur Rehman A. Kalam + 1 more
    • English
    Alternative Splicing: Recent Advances in Health and Disease offers a comprehensive study of this cellular process, its fundamental characteristics, latest advances, and clinical utilization. Opening with an introduction to alternative splicing and its function in generating transcriptome and protein diversity, the book considers the role of this process across a range of diseases and disorders, including cardiovascular disease, cancer, obesity, and viral infections. Key methods used to study alternative splicing are also investigated, including high-throughput sequencing-based methods, bioinformatics tools, computational methods, single-cell sequencing techniques and mass-spectrometry based proteomics.This is followed with analysis of therapeutic approaches associated with alternative splicing. This is an ideal reference for those involved in investigating alternative splicing and its impact to health and disease, and is therefore relevant to researchers across cell biology, molecular biology, pharmacology and related areas.

  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1st Edition
    • Lung-Yi Loey Mak + 1 more
    • English
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.

  • The Vaccine Book

    New Insights, Approaches, and Technologies
    • 3rd Edition
    • Fabio Bagnoli + 2 more
    • English
    The Vaccine Book: New Insights, Approaches and Technologies, Third Edition provides comprehensive information on the current and future world of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases such as AIDS, tuberculosis, and malaria. Edited by a new, highly experienced team of editors, the 3rd edition provides new approaches, design, and vaccine platform tools to develop vaccines quicker.This new edition is fully updated and designed for students, researchers, public health offcials, and all others interested in increasing their understanding of vaccines.

  • Innovation in Emergency Medicine

    Technology Development and Commercialization Handbook
    • 1st Edition
    • Nancy Patterson + 3 more
    • English
    Innovation in Emergency Medicine: Technology Development and Commercialization Handbook is a step-by-step guide to emergency medicine technology innovation reflecting recent trends of industry globalization and value-conscious healthcare. Written by a team of medical, engineering, and business experts, the authors provide a comprehensive resource that leads engineers, clinicians, students, researchers, and entrepreneurs through a clear process for the identification, invention, and implementation of new solutions. Case studies on innovative products from around the world, successes and failures, practical advice, and end-of-chapter 'Getting Started' sections encourage readers to learn from real projects and apply important lessons to their own work. This new volume in the Clinical and Medical Innovation Series will be of interest to every biomedical engineer and those working in emergency medicine who has ever had a good idea for an invention but does not know where and how to start bringing it to the bedside.

  • Microplastics and the Hidden Threat to Human Reproduction

    Plastic Peril
    • 1st Edition
    • Nimra Afzal + 1 more
    • English
    Microplastics and the Hidden Threat to Human Reproduction: Plastic Peril explores the intricate relationship between microplastics and reproductive health, delving into the sources and distribution of microplastics in the environment, human exposure routes, associated risks, the toxicological effects on reproductive health, potential connections to fertility, endocrine disruption, and developmental consequences due to maternal exposure. It includes impacts on both male and female reproductive health, risks during pregnancy, population-level health concerns, strategies for mitigating microplastic exposure, and the policy and regulatory frameworks surrounding this issue. The book also provides insights into the future direction of research and public health initiatives.In essence, it explores how tiny microplastic particles can have significant and far-reaching consequences on human reproductive health, making this a vital and emerging area of concern. This is a comprehensive resource for anyone interested in understanding the various aspects of the microplastics-reprod... health connection and a go-to reference for researchers, healthcare professionals, policymakers, and concerned individuals.

  • Pharmaceutical QbD with Design of Experiments

    Statistical Tools and Applications in Drug Delivery Systems
    • 1st Edition
    • Khushwant Yadav
    • English
    Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment.Researcher... in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

  • Melanin-Concentrating Hormone

    From Metabolism to Sleep Disorders
    • 1st Edition
    • Jackson C. Bittencourt + 1 more
    • English
    Melanin-Concentratin... Hormone: From Metabolism to Sleep Disorders, the latest volume in the Molecular Mediators in Health and Disease series, offers a comprehensive understanding of this multifunctional peptide. The book covers a wide range of topics, including molecular biology of MCH, MCH in organ function, pharmacology, and MCH in disease. Recent developments in MCH imaging and pharmacological modulation are explored, along with the impact of MCH in psychiatric and neurodegenerative disorders and its role in the neuroimmunological modulation of vitiligo. Additionally, MCH is considered in the context of reproductive behavior, sleep, cognition, memory, and peripheral function.The book also explores MCH across various species such as humans, reptiles, non-primate mammals and teleosts. This is an ideal reference for researchers working with MCH across the fields of cell biology, molecular biology, pharmacology, neuroscience, endocrinology, and beyond.

  • Advances in Hepatorenal Syndrome Research

    Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
    • 1st Edition
    • Justin Belcher
    • English
    Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.

  • Pain Conditions of the Head and Face

    A Practical Guide to Diagnosis and Management
    • 1st Edition
    • Anat Galor + 1 more
    • English
    Pain Conditions of the Head and Face: A Practical Guide to Diagnosis and Management provides a user-friendly guide on diagnosing and managing common head and facial pain conditions using new methods and therapies. The book contains practical information, reviewing epidemiology, presenting key features, contributing mechanisms, and including treatment algorithms for common pain conditions of the head and face. Focus is given to aspects of disease that are novel and evolving, and all conditions are discussed within the framework of the latest advances in research and patient care.Doctors seeking to ameliorate their patients’ pain from such maladies as (among many others) neuropathic ocular pain, trigeminal neuralgia, herpetic neuralgia, temporomandibular disorders, burning mouth disorder, and neuropathic ear pain will require no other book to identify their patients’ illnesses and make sure they receive the care they need.

  • Brain Point-of-Care Ultrasound

    Practical Guide and Protocols
    • 1st Edition
    • Camilo N. Rodríguez + 6 more
    • English
    Brain Point-of-Care Ultrasound: Practical Guide and Protocols explores brain hemodynamics and parenchyma examination, providing an orderly and protocolized approach that facilitates individualized clinical decisions with ease. Covering ultrasound configuration, in-depth anatomical knowledge, and advanced parameters, this guide aims to integrate brain ultrasound seamlessly into the Point-of-Care Ultrasound (POCUS) modality, addressing the critical need for comprehensive patient assessment. From basic principles to specialized clinical situations, each section of this guide is meticulously crafted to empower practitioners with practical insights. Chapters explore Doppler spectral wave interpretation, angle correction nuances, autoregulation dynamics, and non-invasive pressure estimations, among others, thus enabling precise monitoring and targeted decision-making. With a focus on integration across disciplines and specialties, this book bridges the gap between classical pathology and contemporary practice, positioning brain ultrasound as a pivotal tool in the armamentarium of modern critical care.

  • Sustainable Wine

    Diversity and Quality
    • 1st Edition
    • Valentina Canuti + 1 more
    • English
    Sustainable Wine: Diversity and Quality is a guide to the environmental, technical, and regulatory aspects of sustainable wine production. The book will begin by covering key foundational concepts, including the intrinsic and perceived qualities of a wine, a key aspect of production regardless of the type of winemaking process. Next, a variety of sustainable, modern viticultural and winemaking practices will be covered. These wines, from organic to vegan, have a reduced environmental impact, can be healthier, and offer special sensory qualities. Each winemaking process covered will begin on the vineyard and end in the glass, offering readers a comprehensive field to table guide to sustainable wines. The book will also separate scientific facts from untested practices that have become commonplace in sustainable winemaking, emphasizing where additional research would be most valuable.

  • Applications of Microfluidics Device Technology

    • 1st Edition
    • Volume 227
    • English
    Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale. This volume highlights the applications of microfluidics in the detection and analysis of infectious diseases caused by bacteria, viruses, fungi, and protozoa. It also explores the use of microfluidic technologies in the diagnosis and study of non-infectious diseases, including cardiovascular disorders, cancer, metabolic diseases, and neurological conditions. It also covered single-cell analysis, high-throughput drug screening, cell sorting, and both preclinical and clinical applications. It also used in role of microfluidics in organ culture, regenerative medicine, and personalized healthcare. It also addresses ethical and regulatory issues in the development and use of microfluidic devices. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.

  • Medicinal and Aromatic Plants in the Post-Genomics Era

    • 1st Edition
    • Rhydum Sharma + 2 more
    • English
    Medicinal and Aromatic Plants in the Post-genomics Era is the first reference to provide a comprehensive look at both traditional medicine plant growth and production alongside the latest research in large-scale, high-throughput technologies. Medicinal and aromatic plants have been used for centuries in the traditional medicine systems of many cultures based on the bioactive compounds within the plants. Most recently, however, the exploration of the secondary metabolites from traditionally medicinal plants has been extended to sectors such as pharmaceutical, nutritional, and even cosmetics. With the development of omics technologies, new insights into the characterization as well as the mining their molecular mechanisms has developed. These technologies have enabled greater understanding of the intricate biochemical pathways associated to the biosynthesis of bioactive compounds. Synthetic biology, CRISPR gene editing, and advanced bioinformatics are also advancing the engineering of these metabolites in alternative modelling systems such as prokaryotic hosts, providing new opportunities for drug discovery, as well as agricultural and environmental sustainability. Medicinal and Aromatic Plants in the Post-genomics Era explores current understanding and recent advances in the application of large-scale, high-throughput technologies for mining the potential of medicinal and aromatic plants.

  • Tissue Organization in Development

    • 1st Edition
    • Volume 171
    • English
    Tissue Organization in Development explores how cells coordinate, communicate, and arrange themselves to build functional tissues during embryonic and postnatal development. The book brings together current perspectives on the molecular, cellular, and mechanical principles that govern tissue patterning, morphogenesis, and structural organization across developing systems. Covering key topics such as cell fate specification, cell–cell interactions, extracellular matrix dynamics, polarity, migration, and tissue remodeling, it highlights how complex biological form emerges from coordinated developmental processes. This volume provides a valuable resource for researchers, students, and professionals interested in developmental biology, cell biology, and tissue formation.

  • Self-Learning AI in Healthcare

    Agentic Systems for Smarter Medicine
    • 1st Edition
    • Rajesh Kumar Dhanaraj + 4 more
    • English
    Self-Learning AI in Healthcare: Agentic Systems for Smarter Medicine covers the transformative potential of advanced artificial intelligence within modern medicine. The book addresses the critical need for self-learning and agentic AI systems that autonomously adapt, refine decision-making, and navigate complex clinical environments with minimal intervention. Chapters provide foundational insights into the rise of self-learning AI and neural networks tailored for adaptive medical systems. Subsequent chapters delve into unsupervised, semi-supervised, and reinforcement learning for autonomous healthcare decision-making, alongside decentralized edge AI approaches. Specialized sections cover personalized medicine, hospital workflow optimization, remote patient monitoring, early disease detection, federated learning for privacy preservation, and more.Further, this book explores AI applications in drug discovery, mental health support, radiology, digital twins, and medical robotics, culminating with an examination of future challenges, ethics, and regulatory frameworks shaping self-learning AI’s trajectory in healthcare. It is tailored to serve a diverse yet specialized audience spanning academic, professional, and research sectors. Healthcare IT professionals and clinical informatics specialists will gain practical guidance for implementing adaptive AI solutions within complex healthcare environments. AI researchers and data scientists focused on developing self-learning models will find cutting-edge methodologies and case studies that advance medical applications.

  • Current State of Alzheimer's and Parkinson's Disease Research and its Pharmacology

    • 1st Edition
    • Volume 108
    • English
    Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Introduction to Tactile Intelligence

    • 1st Edition
    • Shan Luo
    • English
    Introduction to Tactile Intelligence emphasizes the growing importance of tactile intelligence, essential for robots to interact effectively with the physical world. This book explores the science of tactile intelligence, equipping robots and intelligent machines with the ability to touch and feel the world, recognize textures, develop fine motor skills, and even convey emotions through physical contact. It anticipates a future where robots seamlessly integrate with the physical world through tactile intelligence and offers solutions for its development and application in various domains. This book is a good resource for students in robotics to experienced professionals, providing a solid foundation in tactile sensing, tactile-based control, and learning, as well as the integration of tactile data into broader robotic systems. This book provides valuable insights and practical guidance, and it serves as a reference for researchers at all stages of their careers in the dynamic field of tactile development and applications.

  • Machine Learning in Enzymology

    • 1st Edition
    • Volume 742
    • English
    This volume surveys cutting-edge machine learning–based approaches for the study of enzyme catalysis, dynamics, and design. It brings together computational and experimental approaches that integrate molecular simulation, machine learning, and high-throughput data to interrogate enzymatic catalysis at multiple scales. The chapters in the volume highlight how data-driven frameworks complement physics-based models to advance mechanistic understanding and enable rational enzyme engineering.

  • Organic Semiconducting Systems for Applications in Biomedical Engineering

    • 1st Edition
    • Neha Rani Kumar + 1 more
    • English
    Organic Semiconducting Systems for Applications in Biomedical Engineering explores the properties and applications of organic semiconductors, which are conjugated systems made from small organic molecules or polymers that exhibit semiconductor characteristics. These materials offer flexibility, lightweight construction, low cost, and large-area production capabilities. Their tunable electronic and optical properties, along with biocompatibility, such as biosensors, smart drug delivery systems, medical diagnostics, and implantable devices.The book targets professionals and students in the fields of organic electronics, biomedical engineering, biomaterials, and environmental science. It provides a comprehensive understanding of organic conjugated systems and their principles, aiding readers in designing innovative solutions for challenges in medical sectors. Additionally, it delves into the latest research findings and practical applications of organic semiconductors, helping readers stay informed and identify new research opportunities. This book clarifies complex concepts, making it suitable for beginners. It also offers a forward-looking perspective on the potential of organic semiconductors to revolutionize biotechnology, inspiring readers to pursue research and innovation for sustainable development.Overall, this book serves as an essential resource for understanding organic semiconductors in biotechnology, biomedical engineering, and bioelectronic applications.

  • Omics Approaches in Rhizosphere Microbiology: Part A

    • 1st Edition
    • Volume 60
    • English
    Omics Approaches in Rhizosphere Microbiology: Part A series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Network Pharmacology

    Exploring New Horizons in Drug Discovery
    • 1st Edition
    • Veeranoot Nissapatorn + 4 more
    • English
    Network Pharmacology: Exploring New Horizons in Drug Discovery explores the innovative network pharmacology approach—which examines the intricate interactions between disease targets and metabolites—offering a systems-based perspective that is essential for modern drug discovery. Readers will find in-depth discussions on metabolite databases, computational tools, and the role of natural products in drug discovery. Notable topics include network-based approaches to drug repurposing, personalized medicine, and the implications of traditional medicine in pharmacological research, all supported by real-world case studies and advanced computational methodologies.By integrating multiomics data, including metabolite profiling, the book addresses the limitations of conventional methods and opens new pathways for understanding disease mechanisms and therapeutic responses. This is a foundational guide for researchers, pharmaceutical scientists, and academic scholars across diverse fields such as pharmacology, metabolomics, and systems biology.

  • Maize Agriculture

    Remote Sensing, Artificial Intelligence, and Advance Phenotyping
    • 1st Edition
    • Sheikh Mansoor + 5 more
    • English
    As the global population approaches 9 billion, the pressure on agriculture to produce sufficient food will escalate, leading to significant challenges in sustainable food production. Maize Agriculture addresses the urgent need to develop improved maize cultivars grown under advanced technological conditions to combat these future food shortages and nutritional deficiencies. Furthermore, climate change, with its impacts on temperature, precipitation, carbon dioxide levels, and the frequency and severity of extreme weather events, is likely to significantly affect soil water availability, carbon storage, and crop yields. This book digs into these pressing issues, offering an in-depth exploration review of the latest technologies in maize research. This comprehensive resource covers a wide range of topics essential for modern maize agriculture. Beginning with an overview of global maize production, the book progresses through chapters on advanced phenotyping platforms for sustainable maize production. Following that, it explores the integration of genomics and phenomics for maize breeding and the application of AI and machine learning models for genomic trait prediction. Further chapters discuss the use of GIS and global databases for agricultural planning, remote sensing for biotic and abiotic stress monitoring, and advanced AI-based approaches for disease management. Each chapter is carefully structured to provide in-depth insights and practical applications, ensuring a thorough understanding of the subject matter. Maize Agriculture is an invaluable resource for upper-level undergraduate students and researcher across various life science and agriculture disciplines, including agriculture, horticulture, botany, biochemistry, and biotechnology. Additionally, maize breeders, agronomists, and agricultural professionals engaged in maize research will find the actionable strategies in this book invaluable. By integrating digital tools with traditional farming practices, this book ensures that readers are prepared for the future of maize agriculture.

  • Glial Mechanisms in Sleep and Circadian Biology

    • 1st Edition
    • Marcos G. Frank
    • English
    Glial Mechanisms in Sleep and Circadian Biology presents a comprehensive and up-to-date discussion of the role of glial cells in numerous, often unexpected, aspects of sleep. It seamlessly links glial cell activity to the multi-system processes that affect sleep. Experts in the field discuss how glial cells influence the sleep-wake cycle, the accumulation and discharge of sleep drive, the timing of sleep and wake across the 24-hour day, and how glial cells may govern important sleep functions (e.g., brain plasticity and metabolism). This is a book that could well change scientists’ and practitioners’ traditional beliefs about the factors underlying sleep.Users will find the book's content at the forefront of one of the hottest topics in basic sleep research. Over the last decade, scientists have made breakthrough discoveries revealing that sleep is not only a product of neurons, but of neuronal-glial interactions.

  • Handbook of Parkinson's Disease Therapeutics

    • 1st Edition
    • Rosario Moratalla + 1 more
    • English
    Approx.409 pages

  • The Autism Spectrum

    Identification, Understanding, and Treatment in Global Context
    • 1st Edition
    • Matthew K. Belmonte + 1 more
    • English
    This volume summarizes the basic and clinical sciences of autism with an understanding of how research and clinical treatment is affected by recent shifts of focus: from diagnostic categories to symptomatic dimensions, from provider-centered to patient-centered treatment approaches, from high-resource, individualistic country insights to those contributed from global cultures.This volume discusses the field’s current state, whence it has come, where it is going, and how to get there. The volume weds basic and clinical understandings, state-of-the-art multivariate analyses, historical and cross-cultural information and relevance, and a patient-centered focus.

  • Gallin and Ognibene's Principles and Practice of Clinical Research

    • 5th Edition
    • John I. Gallin + 2 more
    • English
    Gallin and Ognibene’s Principles and Practice of Clinical Research, Fifth Edition provides the definitive text on clinical research as written by internationally recognized experts from the National Institutes of Health, the US Food and Drug Administration, academia, and global researchers. This new edition contains more than 30 new authors and 9 new chapters. Topics covered emphasize the role of informatics in clinical research, incorporating clinical outcome assessment into endpoints for decision-making, inclusion of diverse and vulnerable research subjects, patient advocacy groups, rare disease research, preparing research for pandemics, public health emergencies, research opportunities for surgeons, and content on preclinical animal studies.For the international researcher, two new chapters detail international clinical research experiences in South Africa, India, and Pakistan. As with the previous edition, the new release provides readers with summary questions and answers after each chapter.

  • Empowering Health through Lifestyle Medicine

    The Essential Guide for Preventing and Managing Chronic Disease
    • 1st Edition
    • John Anthony Stevens
    • English
    Empowering Health through Lifestyle Medicine: The Essential Guide for Preventing and Managing Chronic Disease combines the most updated and available research with personal insights and experience, using the Lifestyle Medicine 6 pillar framework. The book engages readers not only in the description and efficacy of LM but also in its knowledge and discussions on concepts and behaviors for managing nutrition, physical activity, stress, mental health, and how our interactions with the environment can create a healthier, happier life. It will encourage clinicians to engage their patients more often, and more practically, with lifestyle medicine, while also helping consumers engage with their clinicians.With a goal of helping clinicians and healthcare related professionals prevent and manage lifestyle-related illnesses for life, this evidenced-based book can be used by anyone in healthcare. It is also ideal for those researching illness prevention and chronic disease management to improve health research practice and patient outcomes.

  • Essentials of Stem Cell Biology

    • 4th Edition
    • Robert Lanza + 1 more
    • English
    Essentials of Stem Cell Biology, Fourth Edition is designed for the growing community of scientists, researchers, practitioners, and students embracing the latest advancements in stem cells. This comprehensive book, a collaboration of 7 editors and over 200 pioneering scholars and scientists, provides a thorough understanding of adult and embryonic stem cells. It combines fundamental concepts with cutting-edge research in specific organ systems, ensuring a robust foundation for anyone entering the field. Beyond the basics, the book delves into early development and the differentiation of ectoderm, mesoderm, and endoderm.It covers methods, applications to human diseases, regulation, ethics, and patient perspectives, leaving no stone unturned in the stem cell domain.

  • High Amylose Cereals

    Impact of Starch Structure and Processing on Nutrition
    • 1st Edition
    • Nese Sreenivasulu + 2 more
    • English
    High Amylose Cereals: Impact of Starch Structure and Processing on Nutrition provides a complete focused reference on resistant starch, its source and its efficient and effective use as part of a healthy diet. Moving the reader from the plant to the product, it guides the reader to greater understanding of the potential for these grains. High amylose starch provides a meaningful amount of dietary fiber through the delivery of starch resistant to digestion. This characteristic provides a mechanism to increase the global consumption of fiber. As high amylose grains are being developed and commercialized, a reference is needed describing the general background, nutritional benefits, underlying trait development, and product development. The scope of this book includes topics ranging from the genetics required for the plant to develop high amylose starch to the nuances of creating finished food products with high amylose grain ingredients, including post-harvest processing technologies, and potential for delivering health benefits to consumers. Edited and contributed by leading experts, the book will be valuable for those seeking to understand the role high amylose cereals can play in the global food supply.

  • Principles and Practice of Nephrocardiology

    • 1st Edition
    • Parta Hatamizadeh
    • English
    Principles and Practice of Nephrocardiology provides a comprehensive introduction to the interdisciplinary subspecialty of Nephrocardiology. The book includes detailed descriptions, along with an in-depth exploration of its primary elements and topics. Coverage spans pathophysiology, epidemiology, prevention, diagnosis, prognosis, monitoring, therapy, risk factors, and the systemic diseases that involve both nephrology-related conditions and cardiovascular diseases. The book guides clinicians and general practitioners in multiple interdisciplinary specialties through diagnostic, preventive, and therapeutic approaches to a wide variety of patient populations. It also opens a myriad of new avenues for future research and guidance for approaching multiple medical topics.

  • Fruit and Vegetable Nutrition

    Practical Applications for Improving Human Health
    • 1st Edition
    • Yang Shan
    • English
    Fruit and Vegetable Nutrition: Practical Applications for Improving Human Health is a comprehensive resource that provides insights into the nutritional benefits of fruits and vegetables, their role in human health, and the many practical applications for functional food innovation. Edited by Dr. Yang Shan who has over 40 years of experience in fruit and vegetable science research, this book explores how certain fruits and vegetables such as berries, citrus and nightshades can benefit chronic conditions such as cardiovascular disease, obesity and diabetes while linking diet to improved health outcomes. The book also addresses the role of fruits and vegetables and their vital bioactive compounds in the development of functional foods and nutraceuticals offering insights for professionals in the food industry who aim to create health-promoting products.Fruit and Vegetable Nutrition: Practical Applications for Improving Human Health also discusses how certain processing techniques can retain essential nutrients and improve food product quality and how specific combinations of fruits and vegetables can promote the growth of key gut bacteria, improving health status, inflammation and the gut microbiome. The book concludes with the role of smart equipment in the fruit and vegetable industry to streamline quality and improve nutritional outcomes and how biosynthesis technology can offer advantages in the production of fruits and vegetables, contributing to sustainable practices.

  • Congenital Adrenal Hyperplasia

    A Comprehensive Guide
    • 2nd Edition
    • Peter C. Hindmarsh + 1 more
    • English
    Congenital Adrenal Hyperplasia: A Comprehensive Guide, Second Edition provides a fully-illustrated edition that outlines the basics of CAH and its interrelation with hormones and bodily function, including updated content on the latest clinical research. A new chapter dedicated to gene therapy covers principles, current status, the latest research developments, and potential treatments for congenital adrenal hyperplasia. In addition, this new release updates patient profiles due to several new clinical studies in CAH for improved condition management, with practical information on how to deal with emergencies, medic alert emergency kits, emergency injection needles, handling illness, surgery, and more.In addition, new assays are incorporated for the analysis of pituitary and adrenal hormones for the determination of the disease. This new edition continues to be a vital reference to pediatric endocrinologists as well as primary care providers to help affected patients with an updated model of care and appropriate treatment. Patients and family members will continue to benefit from the new trend-forward information presented and will be empowered to approach their health care providers with the expectation of receiving individualized care and treatment of the disorder.

  • PROTACs Overcome Resistance to Cancer Therapies

    • 1st Edition
    • Daohong Zhou
    • English
    PROTACs Overcome Resistance to Cancer Therapies explores the transformative potential of proteolysis targeting chimeras (PROTACs) in addressing one of oncology’s greatest challenges: drug resistance. Edited by Dr. Daohong Zhou, this volume brings together leading experts to present the latest advances in targeted protein degradation for cancer treatment. The book covers foundational principles of PROTAC design, mechanisms of action, and their advantages over traditional small molecule inhibitors. It delves into strategies for targeting undruggable proteins, overcoming resistance in various cancer types, and mitigating emerging resistance to PROTACs. Case studies include BCL-xL, KRAS, STAT3, and EGFR-targeting PROTACs, with insights into clinical translation and precision medicine. This resource equips cancer researchers, oncologists, and pharmaceutical scientists with practical guidance and cutting-edge knowledge. It serves as both a reference and a roadmap for developing next-generation therapeutics, making it essential for those advancing cancer drug discovery and translational medicine.

  • Intracranial Arteriopathies

    From Anomalies to Abnormalities
    • 1st Edition
    • Marialuisa Zedde + 1 more
    • English
    In this complex and often misunderstand area of medical science, Intracranial Arteriopathies: From Anomalies to Abnormalities provides neuroradiologists with a systematic approach to understanding intracranial arteriopathies, performing advanced neuroimaging techniques, interpreting imaging results, and allowing for more accurate diagnoses and treatment plans. By delving into the epidemiology and pathophysiology of intracranial artery diseases, this book aims to clarify the distinctions between anomalies and abnormalities, offering invaluable insights for both clinical practice and research. The contents of this book span a wide range of topics, from common causes like atherosclerosis to rare conditions such as Moyamoya disease and post-infectious vasculitides. Each chapter, authored by leading experts in the field, covers essential aspects including foundational details, imaging methods, diagnostic criteria and guidelines, and differential diagnoses. The book also explores systemic diseases that impact intracranial arteries, such as fibromuscular dysplasia and neurofibromatosis, providing a holistic view of the subject matter. Through detailed case studies and practical examples, readers will gain a deep understanding of the pathophysiology and clinical patterns of these conditions. For neuroradiologists, Intracranial Arteriopathies: From Anomalies to Abnormalities offers a pragmatic approach to understanding the complexities of intracranial arteriopathies, enhancing their ability to identify and study these conditions. Clinicians will find this resource particularly beneficial for improving their diagnostic accuracy and management strategies, ultimately leading to better patient outcomes. This book is an essential reference, bridging the gap between theory and clinical practice.

  • Impacts of Pollutants of Emerging Concern on Ecosystems and Human Health

    • 1st Edition
    • Li Zhou + 3 more
    • English
    Impacts of Pollutants of Emerging Concern on Ecosystems and Human Health highlights the occurrence and the environmental and health risks of emerging contaminants. It covers the detection, source identification, and concentration of various emerging pollutants, such as pharmaceuticals, pesticides, and microplastics. This book delves into the transport, transformation, and bioaccumulation of these pollutants, analyzing their ecological and human health impacts. Additionally, it provides an overview of conventional and advanced treatment methods, presenting innovative, eco-friendly solutions for pollution control and remediation.

  • Cytomegalovirus

    From Biology to Clinical Aspects
    • 1st Edition
    • Adriana Calderaro
    • English
    Cytomegalovirus: From Biology to Clinical Aspects delves into the intricate world of Cytomegalovirus (CMV), offering a comprehensive exploration of its fundamental biology and clinical implications. This book serves as an essential resource for understanding CMV from its epidemiology and infection routes to its pathogenesis and immunity. It addresses the virus’s impact on various demographics and provides insights into diagnostic and treatment strategies. The book covers critical aspects such as vulnerability indicators, cellular damage, laboratory detection, and management strategies. It stands out as a valuable reference for current clinical practices and fundamental scientific knowledge on CMV, offering methods to interpret diagnostic results.

  • Artificial Intelligence (AI) in cancer biology

    Advancements in Diagnosis and Treatment
    • 1st Edition
    • Sadhna Aggarwal
    • English
    Artificial Intelligence (AI) in cancer biology: Advancements in Diagnosis and Treatment explores the revolutionary impact of AI on cancer biology and oncology. This comprehensive volume delves into AI technologies, including machine learning and deep learning, enhancing our ability to understand, diagnose, and treat cancer with unprecedented precision. The book covers a wide range of topics, from cancer biology fundamentals to AI-driven techniques in diagnosis and personalised treatment. It discusses medical imaging, genomics, drug discovery, and predictive modelling, along with ethical and regulatory considerations, offering a holistic view of AI in cancer research. For academic audiences, this book provides invaluable insights into improving clinical outcomes and patient care. Researchers and clinicians will benefit from the detailed analysis of AI applications, while students and scholars will find a wealth of information to support their studies and future innovations in cancer treatment.

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