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Books in Life sciences

  • Screening Methods in Pharmacology

    • 1st Edition
    • Robert Turner
    • English
    Screening Methods in Pharmacology focuses on the methods for screening substances for pharmacological activities and discussions of organization of screening programs. The manuscript first offers information on the biochemistry of the nervous system and organization of screening, as well as mechanisms of drug effects within the autonomic system; mechanisms within the parasympathetic and symphatetic systems; and neuropharmacological tests in blind screening. The book also takes a look at general and quantal responses. The publication reviews depressants of the central nervous system and ataractic (tranquillizing, neuroleptic) agents. Topics include natatory exhaustion, motor deficit, righting reflex, pentylenetetrazol (metrazol) antagonism, head-withdrawal reflex, and avoidance of electrical shock. The book also ponders on analgesics and oxytoxic, antiserotonin, and anti-inflammatory agents. Discussions focus on narcotic and nonnarcotic analgesics, erythema, inhibition of ascites, and pleural fluid. The manuscript is a valuable reference for readers interested in the screening methods in pharmacology.

  • Criteria (Dose/Effect Relationships) for Organochlorine Pesticides

    Report of a Working Group of Experts Prepared for the Commission of the European Communities, Directorate-General for Employment and Social Affairs, Health and Safety Directorate
    • 1st Edition
    • M. Mercier
    • English
    Criteria (Dose/Effect Relationships) for Organochlorine Pesticides presents the effect of organochlorine compounds on the immunological processes. This book deals with several organochlorine pesticides. Organized into 15 chapters, this book begins with an overview of the properties and toxicology of dichlorodiphenyl trichloroethane (DDT), a potent non-systemic stomach and contact insecticide of high persistence on solid surface. This text then examines the absorption, metabolism, and excretion of lindane in laboratory animals and in humans as well. Other chapters consider the studies on the carcinogenic potential as well as the mutagenic effects of dieldrin. This book discusses as well the metabolism and pharmacokinetics of endrin, which is a non-systemic and persistent insecticide used primarily on field crops. The final chapter deals with the need for further evaluation of any possible long-term risks to humans from the production and use of the technical product. This book is a valuable resource for agriculturists and research workers.

  • Aspirin and the Salicylates

    • 1st Edition
    • K. D. Rainsford
    • English
    Aspirin and the Salicylates focuses principally on aspirin. Topics ranging from analytical chemistry and pediatric medicine, taxonomy and cartels, enzymology and toxicity, to renal functions and rheumatology are also included in this compilation. This book emphasizes that salicylates are polycompetent drugs that influence a large number and variety of biological processes. Their multifactorial actions, in relation to the known therapeutic and toxic effects are clearly described. This text likewise provides a refreshing multidisciplinary approach to aspirins that cover the whole extent from chemical to clinical aspects. This publication is a good reference for clinicians, pharmacists, and students intending to acquire general knowledge of the aspirin and salicylates.

  • Bone Mineral Metabolism in Cancer

    Recent Results in Cancer Research
    • 1st Edition
    • Janusz Szymendera
    • V. G. Allfrey + 2 more
    • English
    Recent Results in Cancer Research: Bone Mineral Metabolism in Cancer presents the clinical approach to bone tissue metabolism, which depends on studying the plasma state, renal handling, kinetics, and balance of calcium and inorganic phosphate. This book discusses the problems of bone mineral metabolism in patients with cancer. Organized into five chapters, this book begins with an overview of the two major phases of bone mineral, namely, amorphous calcium phosphate and crystalline bone apatite. This text then examines the plasma state and renal handling of calcium and inorganic phosphate under controlled metabolic conditions. Other chapters consider the variability of each parameter in the majority of patients without bone secondaries. This book discusses as well the normal remodeling of bone in fertile-age women. The final chapter deals with the plasma state, renal handling, and kinetics of calcium and phosphate in plasmacytoma patients. This book is a valuable resource for oncologists.

  • Physiology and Behaviour of Marine Organisms

    Proceedings of the 12th European Symposium on Marine Biology, Stirling, Scotland, September 1977
    • 1st Edition
    • D.S. McLusky + 1 more
    • English
    Physiology and Behavior of Marine Organisms covers the proceedings of the 12th European Symposium on Marine Biology, held in University of Stirling, Stirling, Scotland on September 5-12, 1977. This book is organized into six parts encompassing 45 chapters. The first part deals with metabolism-related topics in marine organisms, including nutrition, enzyme activity, respiration, and physiological adaptation. The succeeding parts consider the mechanism of osmoregulation, ionic transport, biological permeation, and the structure and function of chloride cells in gills. These parts also explore the physiological aspects of marine animals in the water's chemical environment. These topics are followed by discussions of the mechanisms of immobilization and detoxification of heavy metals and other pollutants by marine organisms, as well as the interspecies differences in pollutant tolerance of several marine creatures. The concluding parts look into the behavior, reproduction, and development of other marine animals. This book will be of great value to marine biologists, physiologists, researchers, and advance students.

  • Agricultural Insurance

    Principles and Organization and Application to Developing Countries
    • 1st Edition
    • P. K. Ray
    • English
    Agricultural Insurance: Principles and Organization and Application to Developing Countries states that agriculture is subject to special elements of uncertainty. The risk inherent in agriculture has been exhaustively discussed in the text. Risks in agriculture can be characterized as property risk and personal risk. Natural risk such as storms, plant diseases, and insect pests is another topic covered in the book. A type of risk that is identified as drought, inundation, frost and freeze, hail, and tornado is called meteorological risk. The book also discusses another form of risk, which is named social risk. Occurrence such as fire, theft or burglary, embezzlement, and technological change belongs to this type of risk. A chapter of the book is devoted to the ways on how to remedy the risks enumerated. Another section of the book defines the term insurance. This section introduces such topic as probability, uncertainty, and the law of large numbers. The book notes that in order for agricultural risk to be insurable, it must satisfy some parameters. The text will provide valuable insight for farmers, financial planners, statisticians, students, and researchers in the field of risk management.

  • Introduction to Nuclear Techniques in Agronomy and Plant Biology

    Pergamon International Library of Science, Technology, Engineering and Social Studies
    • 1st Edition
    • Peter B. Vose
    • English
    Introduction to Nuclear Techniques in Agronomy and Plant Biology is a 15-chapter book that begins with an explanation of the nature of isotopes and radiation, nuclear reactions, and radioisotopes. Subsequent chapters describe the radioassay, use of stable isotopes as tracers, and activation analysis for biological samples. Other chapters discuss X-ray fluorescence spectrography for plants and soils; autoradiography; isotopes in soils studies; isotopic tracers in field experimentation; and nuclear techniques in plant science and soil water. The last chapter centers on the radiation and other induced mutations in plant breeding.

  • Receptors and Centrally Acting Drugs Pharmacokinetics and Drug Metabolism

    Proceedings of the 4th Congress of the Hungarian Pharmacological Society, Budapest, 1985
    • 1st Edition
    • E. S. Vizi + 2 more
    • English
    Advances in Pharmacological Research and Practice, Volume 2: Receptors and Centrally Acting Drugs presents the proceeding of the 4th Congress of the Hungarian Pharmacological Society, held in Budapest, Hungary in 1985. This book presents a comprehensive view of the developments in the fields of receptors and centrally acting drugs as well as in pharmacokinetics and drug metabolism. Organized into two sections encompassing 25 chapters, this volume begins with an overview of prejunctional regulation of neuromuscular transmission. This text then explores the whole-body autoradiography that is used extensively in toxicological research and screening. Other chapters consider the three major classes of models used in pharmacokinetics. This book discusses as well the various aspects of melanin–drug interactions. The final chapter deals with the investigation on the melanin affinity of amphetamine derivatives. This book is a valuable resource for pharmacologists, pharmacokineticists, and researchers.

  • Methods of Animal Experimentation

    Volume I
    • 1st Edition
    • William I. Gay
    • English
    Methods of Animal Experimentation, Volume I, provides information on the most common methods for using animals as tools in the search for new biological knowledge. The techniques described will facilitate the most efficient use of research animals and provide guidelines for their utmost comfort and welfare. The text is arranged according to specific research methods rather than to organ system or disease category. This approach gives the reader a broad view of the techniques involved in specific fields and describes the range of usefulness of these techniques. The first five chapters of the present volume describe basic information, methods, and principles involved in managing animals for experimental procedures. The remaining chapters deal with special techniques which have been demonstrated to be distinct, useful methods for using laboratory animals as a basic biomedical research tool. The descriptions of both fundamental and well-developed techniques of animal experimentation in various research fields should be useful to graduate students and experienced scientists who must consider variations in research approaches. The book is a source of information for the scientist administrator who is frequently confronted with different proposed approaches to biological research projects utilizing animals.

  • Recent Advances in Neuropsycho-Pharmacology

    Selected Papers from the 12th Congress of the Collegium Internationale Neuro-Psychopharmacologicum, Göteborg, Sweden, 22-26 June 1980
    • 1st Edition
    • B. Angrist + 2 more
    • English
    Recent Advances In Neuropsychopharmacol... contains selected papers from the 12th Congress of the Collegium Internationale Neuro-Psychopharmaco... held in Gõteborg, Sweden, 22-26 June 1980. The 47 papers in the volume are organized into six parts. The papers in Part I deal with the subject of psychostimulants in psychiatric research. Topics covered include the effect of chronic d-amphetamine and chronic apomorphine treatment on non-human primate social and solitary behavior; and the behavioral effects of dopamine agonists. Part II assesses the prescription of psychotropic drugs by general practitioners. Part III examines blood platelets as a model system for central monoaminergic neurons. Part IV focuses on anxiety pathways in the brain. Part V considers prospects for a biochemical classification system in psychiatry. Part VI presents pharmacokinetic studies of psychotropic drugs. Part VI contains two papers on the renal function and renal histology of lithium patients on maintenance lithium therapy and pre-lithium patients; and the treatment of refractory schizophrenia.

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