Books in Life sciences

Activins and Inhibins

1st Edition
Volume 85
March 7, 2011
Gerald Litwack
English
Hardback
9 7 8 0 1 2 3 8 5 9 6 1 7
eBook
9 7 8 0 1 2 3 8 5 9 6 2 4

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.This volume focuses on activins and inhibins.

Animal Models of Human Disease

1st Edition
Volume 100
March 4, 2011
Karen Chang + 1 more
English
Hardback
9 7 8 0 1 2 3 8 4 8 7 8 9
eBook
9 7 8 0 1 2 3 8 4 8 7 9 6

Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining new therapies. Animal Models of Human Disease reviews the latest research and developments in this field.

Pharmacology of 5-HT6 receptors, Part II

1st Edition
Volume 96
March 1, 2011
Franco Borsini
English
Hardback
9 7 8 0 1 2 3 8 5 9 0 2 0
eBook
9 7 8 0 1 2 3 8 5 9 0 3 7

The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.

Fragment Based Drug Design

1st Edition
Volume 493
February 28, 2011
Lawrence C. Kuo
English
Hardback
9 7 8 0 1 2 3 8 1 2 7 4 2
eBook
9 7 8 0 1 2 3 8 1 2 7 5 9

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits.

Immunology, Inflammation and Diseases of the Eye

1st Edition
February 26, 2011
Darlene A. Dartt + 3 more
English
Paperback
9 7 8 0 0 8 1 0 1 6 5 9 6
eBook
9 7 8 0 1 2 3 8 1 9 7 5 8

This selection of articles from the Encyclopedia of the Eye provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more.

Biomedical Hydrogels

1st Edition
February 26, 2011
Steve Rimmer
English
Paperback
9 7 8 0 0 8 1 0 1 7 4 1 8
eBook
9 7 8 0 8 5 7 0 9 1 3 8 3

Hydrogels are very important for biomedical applications because they can be chemically manipulated to alter and control the hydrogel’s interaction with cells and tissues. Their flexibility and high water content is similar to that of natural tissue, making them extremely suitable for biomaterials applications. Biomedical hydrogels explores the diverse range and use of hydrogels, focusing on processing methods and novel applications in the field of implants and prostheses. Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imaging implants in situ is also discussed. With its distinguished editor and international team of contributors, Biomedical hydrogels is an excellent reference for biomedical research scientists and engineers in industry and academia, as well as others involved in research in this area, such as research clinicians.

Reproductive and Developmental Toxicology

1st Edition
February 25, 2011
Ramesh C. Gupta
Ramesh C. Gupta
English
eBook
9 7 8 0 1 2 3 8 2 0 3 3 4

Reproductive toxicology is a complex subject dealing with three components—parent, placenta, and fetus—and the continuous changes that occur in each. Reproductive and Developmental Toxicology is a comprehensive and authoritative resource providing the latest literature enriched with relevant references describing every aspect of this area of science. It addresses a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, food additives, nutraceuticals and pharmaceuticals, and metals, among others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, and is the only resource to include reproductive and developmental toxicity in domestic animals, fish, and wildlife.

Food Preservation Process Design

1st Edition
February 24, 2011
Dennis R. Heldman
English

The preservation processes for foods have evolved over several centuries, but recent attention to non-thermal technologies suggests that a new dimension of change has been initiated.The new dimension to be emphasized is the emerging technologies for preservation of foods and the need for sound base of information to be developed as inputs for systematic process design. The focus of the work is on process design, and emphasizes the need for quantitative information as inputs to process design.The concepts presented build on the successful history of thermal processing of foods and use many examples from these types of preservation processes. Preservation of foods by refrigeration, freezing, concentration and dehydration are not addressed directly, but many of the concepts to be presented would apply. Significant attention is given to the fate of food quality attributes during the preservation process and the concept of optimizing process parameters to maximize the retention of food quality.

The Psychology of Learning and Motivation

1st Edition
Volume 54
February 22, 2011
Brian H. Ross
English
eBook
9 7 8 0 1 2 3 8 5 5 2 8 2

The Psychology of Learning and Motivation series publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter thoughtfully integrates the writings of leading contributors, who present and discuss significant bodies of research relevant to their discipline. Volume 51 includes chapters on such varied topics as emotion and memory interference, electrophysiology, mathematical cognition, and reader participation in narrative.

Advances in Parasitology

1st Edition
Volume 74
February 17, 2011
David Rollinson + 1 more
English
Hardback
9 7 8 0 1 2 3 8 5 8 9 7 9
eBook
9 7 8 0 1 2 3 8 5 8 9 8 6

First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies on parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on various topics, including control of human parasitic diseases and global mapping of infectious diseases. The 2009 impact factor is 6.231.

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