Books in Life sciences

Cancer and Development

1st Edition
Volume 94
February 14, 2011
Michael Dyer
English
Hardback
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eBook
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In recent years, a number of molecular pathways and cellular processes that are essential for normal vertebrate development have been implicated in cancer initiation and progression. In this volume, leaders in the field of cancer genetics and developmental biology share recent insights into the importance of developmental pathways for tumorigenesis. These discoveries provide important avenues for innovative new approaches to treating some of the most challenging developmental tumors.

The Unfolded Protein Response and Cellular Stress, Part C

1st Edition
Volume 491
February 14, 2011
P. Michael Conn
English
Hardback
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eBook
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This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights

Progress in Medicinal Chemistry

1st Edition
Volume 50
February 9, 2011
G. Lawton + 1 more
English
eBook
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Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems.

Advances in Genetics

1st Edition
Volume 73
February 7, 2011
Stephen F. Goodwin + 2 more
English
Hardback
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eBook
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Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

Determining Mycotoxins and Mycotoxigenic Fungi in Food and Feed

1st Edition
February 7, 2011
Sarah De Saeger
English
Paperback
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eBook
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Mycotoxins - toxic secondary metabolites produced by mycotoxigenic fungi – pose a significant risk to the food chain. Indeed, they may be the most hazardous of all food contaminants in terms of chronic toxicity and legislative limits on their levels in food and feed continue to be developed worldwide. Rapid and reliable methods for the determination of both mycotoxigenic fungi and mycotoxins in food and feed are therefore essential. This book reviews current and emerging methods in this area.Part one focuses on the essentials of mycotoxin determination, covering sampling, sample preparation and clean-up and key determination techniques, such as chromatographic separation, liquid chromatography-mass spectrometry and immunochemical methods. Part two then goes on to describe quality assurance, official methods and performance criteria for determining mycotoxins in food and feed. Topics covered include laboratory accreditation, method validation and measurement uncertainty. The development and analysis of biomarkers for mycotoxins are discussed in part three. Individual chapters focus on detecting exposure in humans and animals. Part four is concerned with the processes involved in determining mycotoxigenic fungi in food and feed. It also describes the identification of genes and gene clusters involved in mycotoxin synthesis, as well as DNA barcoding of toxigenic fungi. Finally, part five explores some of the emerging methods for mycotoxin analysis, ranging from bio-sensing to spectroscopic techniques.With its distinguished editor and international team of contributors, Determining mycotoxins and mycotoxigenic fungi in food and feed is a standard reference for all those concerned with reducing mycotoxin contamination in the food chain.

Advances in Agronomy

1st Edition
Volume 110
January 31, 2011
Donald L. Sparks
English
eBook
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Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial.

Advances in Clinical Chemistry

1st Edition
Volume 53
January 26, 2011
Gregory S. Makowski
English
eBook
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Volume 53 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.

Development of the Nervous System

3rd Edition
January 25, 2011
Dan H. Sanes + 2 more
English
eBook
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Development of the Nervous System presents a broad and basic treatment of the established and evolving principles of neural development as exemplified by key experiments and observations from past and recent times. The text is organized ontogenically. It begins with the emergence of the neural primordium and takes a chapter-by-chapter approach in succeeding events in neural development: patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and developmental plasticity. Finally, in the last chapter, with the construction phase nearing completion, we examine the emergence of behavior. This new edition reflects the complete modernization of the field that has been achieved through the intensive application of molecular, genetic, and cell biological approaches. It is richly illustrated with color photographs and original drawings. Combined with the clear and concise writing, the illustrations make this a book that is well suited to students approaching this intriguing field for the first time.

Essentials of Medical Biochemistry

1st Edition
January 24, 2011
Chung Eun Ha + 1 more
English
eBook
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Expert biochemist N.V. Bhagavan’s new work condenses his successful Medical Biochemistry texts along with numerous case studies, to act as an extensive review and reference guide for both students and experts alike. The research-driven content includes four-color illustrations throughout to develop an understanding of the events and processes that are occurring at both the molecular and macrolecular levels of physiologic regulation, clinical effects, and interactions. Using thorough introductions, end of chapter reviews, fact-filled tables, and related multiple-choice questions, Bhagavan provides the reader with the most condensed yet detailed biochemistry overview available. More than a quick survey, this comprehensive text includes USMLE sample exams from Bhagavan himself, a previous coauthor.

Proteases in Health and Disease

1st Edition
Volume 99
January 24, 2011
Enrico Di Cera
English
Hardback
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eBook
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Proteases occur naturally in all organisms. They are enzymes that are involved in many physiological reactions such as digestion of food and blood clotting. This volume reviews their role in health and disease and presents the latest research and developments.

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