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Books in Life sciences

  • Haematin Enzymes

    A Symposium of the International Union of Biochemistry Organized by the Australian Academy of Science Canberra
    • 1st Edition
    • J. E. Falk + 2 more
    • English
    International Union of Biochemistry, Volume 19: Haematin Enzymes, Part 1 provides information pertinent to the fundamental aspects of hematin enzymes. This book covers a variety of topics, including porphyrin complexes, chemical reactions of iron complexes, hemoprotein molecules, metalloporphyrins, and oxyhemoglobins. Organized into 22 chapters, this volume begins with an overview of the relevance of magnetic susceptabilitty and magnetic resonance data. This text then examines studies on electron-transfer processes involving metal ions and shows how the electronic structures of the hem enzymes may be relevant to the types of electron-transfer that can take place. Other chapters consider the implications of the coordination of organic molecules to metal ions. This book presents as well a comparison between known properties and reactions of some simple iron complexes with chelating and conjugated ligands. The final chapter deals with the chemical structures of the prosthetic groups of the cytochromes of type a. This book is a valuable resource for scientists, theorists, and research workers.

  • Immunological Methods

    Volume IV
    • 1st Edition
    • Ivan Lefkovits + 1 more
    • English
    Immunological Methods, Volume IV provides information pertinent to the methods in immunological research. This book focuses on cells, clones, and cell lines, as well as on their components and secreted products. Organized into 21 chapters, this volume begins with an overview of hybridoma methodology as the most celebrated immunological method. This text then discusses cell fusion, hybridoma technology, and everything related to monoclonal antibodies. Other chapters consider another molecular biology method, which describes the procedure required for establishing a partitioned cDNA-library. This book provides as well a comprehensive analysis of mRNA populations in which every messenger species appears as a distinct element, and so provides accurate answers to questions concerning genetic complexity. The final chapter provides an example of how transgenic mice can be used to study the development of T cell repertoires. This book is a valuable resource for cell biologists, scientists, immunologists, and research workers.

  • Immunology in Clinical Medicine

    • 3rd Edition
    • J. L. Turk
    • English
    Immunology in Clinical Medicine is an introduction to immunology in clinical medicine, with emphasis on immunological concepts underlying disease processes. The effect of drugs known to suppress immunological processes are considered especially in relation to whether they operate by really suppressing immunological processes or whether they have other actions. Comprised of 17 chapters, this book begins with an overview of the nature of the immune response, followed by a discussion on reactionS in the tissues mediated by humoral antibodies. The reader is then introduced to reactions in the tissues caused by the cell-mediated immune response; immunological processes in infective diseases; and the concept of autoimmunity and its relation to disease. Subsequent chapters focus on the immunology of diseases such as cancer, skin diseases, connective tissue diseases, and diseases of the intestinal tract, respiratory tract, liver, and amyloidosis. The final chapter is devoted to the role of the clinical immunologist in patient care and therapy. This monograph is intended for students and practitioners of clinical medicine.

  • An Introduction to General Virology

    • 1st Edition
    • Thomas M. Bell
    • English
    An Introduction to General Virology provides information pertinent to all aspects of virology. This book discusses the viruses affecting plants and insects. Organized into 25 chapters, this book begins with an overview of prevention of disease that can be effected by the immunization of susceptible hosts to produce circulating antibodies that neutralize viral infectivity. This text then discusses the general properties of the viruses. Other chapters consider the methods of preparing tissue cultures and explain the methods used for titrations of serum antibodies and serological identification of viruses. This book discusses as well the spread of diseases, the various invasion routes of the body, and the multitude of viruses which cause respiratory symptoms and which cannot easily be conquered. The final chapter deals with the types of vaccine in use. This book is a valuable resource for undergraduates in Medicine and Science and for postgraduates in the class of Public Health.

  • The Peptides

    Volume II Synthesis, Occurrence, and Action of Biologically Active Polypeptides
    • 1st Edition
    • Eberhard Schröder + 1 more
    • English
    The Peptides, Volume II: Synthesis, Occurrence, and Action of Biologically Active Polypeptides focuses on the synthesis of biologically active polypeptides and analogues. The publication first offers information on linear peptides and heterodetic cyclic peptides. Discussions focus on depsipeptides, polycyclic and monocyclic disulfides, naturally occurring biologically active peptides, glandular hormones, and tissue hormones. The text then ponders on homodetic cyclic peptides, including homodetic cyclic homomeric peptide antibiotics, polycyclic biologically active polypeptides, and homodetic cyclic heteromeric peptide antibiotics. The manuscript takes a look at the problems related with the synthesis of biologically active polypeptides, giving emphasis to a number of movements which elaborated on the matter and the advancements of preparative techniques and approaches leading to the purification of intermediates and end products. The publication is a valuable reference for researchers interested in the occurrence, synthesis, and action of biologically active polypeptides.

  • Chemistry and Methods of Enzymes

    • 3rd Edition
    • James B. Sumner + 1 more
    • English
    Chemistry and Methods of Enzymes, Third Edition focuses on the processes, methodologies, and reactions in enzyme chemistry, as well as kinetics, nucleases, esterases, and carbohydrates. The publication first underscores the general properties of enzymes, including chemical nature, occurrence, numerical characterization of enzyme concentration, kinetics of enzyme reactions, preparation of commercial enzymes, purification and preservation of enzymes, relations of vitamins to enzymes, and zymogens and kinases. The text then takes a look at esterases and carbohydrates. Topics include pectin depolymerase, heparinase, xylanase, chitinase, dextranase, trehalase, nucleotide phosphatases, glucosulfatase, and gastric lipase. The manuscript examines nucleases, nuclein deaminases, amidases, proteolytic enzymes, and hydrases. Discussions focus on enolase, aconitase, peptidases as metalloproteins, glutaminases, aspartase, urease, adenosine deaminase, and nucleoside phosphorylase. The book also elaborates on iron and copper enzymes, dehydrogenases containing coenzymes I and II, and yellow enzymes. The text is a dependable source of data for chemists and researchers wanting to dig deeper into the chemistry and methods of enzymes.

  • Control of Energy Metabolism

    • 1st Edition
    • Britton Chance + 2 more
    • English
    Control of Energy Metabolism: A Colloquium of the Johnson Research Foundation focuses on the processes, reactions, and approaches involved in the control of energy metabolism. The selection first offers information on the respiratory chain as a model for metabolic control in multi-enzyme systems, dynamics and control in cellular reactions, and computer-based analysis of biochemical data. The text then explores purification and properties of rabbit skeletal muscle phosphofructokinase; multiple forms of heart phosphofructokinase; and mechanisms of inhibition and activation of phosphofructokinase in Novikoff ascites tumor cells. Discussions focus on the properties of purified phosphofructokinase; effect of heart extracts on reactivation of phosphofructokinase; active and inactive forms of phosphofructokinase; and effect of hexose phosphate and adenylic nucleotides on reactivation of phosphofructokinase. The manuscript takes a look at enzyme and metabolite profiles; coordinated stimulation of hexokinase and phosphofructokinase by phosphate in a reconstituted system of glycolysis; control of hexokinase in ascites tumor glycolysis; and cation flux across the mitochondrial membrane as a possible pacemaker of tissue metabolism. The selection is a vital reference for biochemists and researchers interested in the control of energy metabolism.

  • The Anatomy of the Developing Lung

    • 1st Edition
    • John Emery
    • English
    The Anatomy of the Developing Lung provides an introduction to the anatomical studies of the lung. This book discusses the structure of the developing fetal lung and reviews the knowledge on the development of goblet cells and glands in the trachea-bronchial tree in man. Organized into 11 chapters, this book begins with an overview of the general pattern of growth of the fetal lung and the development of the alveoli. This text then examines the important ultrastructural characteristics of the mature lung and explains the changes in the muscle of the blood vessels around birth. Other chapters consider the role and development of cartilage and examine the relationship between collagen and elastic tissue. This book discusses as well the general function of mature collagen. The final chapter deals with the measurement of postnatal lung weight. This book is a valuable resource for pediatricians, histologists, physiologists, clinicians, pathologists, and research workers.

  • Biochemistry and Physiology of Protozoa

    • 1st Edition
    • André Lwoff
    • English
    Biochemistry and Physiology of Protozoa, Volume I focuses on the chemical and physiological features of Protozoa, including nutrition, metabolism, and growth of phytoflagellates, Trypanosomidae and Bodonidae, biochemistry of ciliates and Plasmodium, and the influence of antimalarials. The selection first offers information on the biochemistry of Protozoa and phytoflagellates, including sexuality in Chlamydomonas, growth factors and chemical asepsis, descriptive chemistry and phylogenetic relationships, evolutionary aspects of photosynthesis, nutrition and biochemistry of Protozoa, and the biochemical evolution of Protozoa. The text then ponders on the nutrition of parasitic flagellates and metabolism of Trypanosomidae and Bodonidae. The publication takes a look at the nutrition of parasitic amebae, biochemistry of Plasmodium and the influence of antimalarials, and the biochemistry of ciliates in pure culture. Topics include carbon metabolism and respiration, nitrogen metabolism, antimalarial compounds and their influence on the metabolism of malarial parasites, metabolism of malarial parasites, and nutrition of the dysentery ameba, Entamoeba histolytica. The selection is a valuable reference for cytologists, geneticists, and pathologists interested in the biochemistry and physiology of protozoa.

  • Introduction to Enzymology

    • 1st Edition
    • Alan H. Mehler
    • English
    Introduction to Enzymology focuses on the processes, methodologies, reactions, and approaches involved in enzyme chemistry. The book first offers information on the hydrolysis of peptides and proteins and fermentation and oxidation of major metabolic fuels. Discussions focus on oxidation of fatty acids, alternative pathways of carbohydrate metabolism, Krebs citric acid cycle, free energy and the concept of bond energy, pyruvate oxidation and acetyl coenzyme A formation, and glycolysis. The text then elaborates on the transfer of oxygen, hydrogen, and electrons and sugars and sugar derivatives. The publication takes a look at polynucleotides and their components, amino acids, and acids and acid derivatives. Topics include carbonic anhydrase, mechanism of action of pyridoxal phosphate enzymes, aromatic ring biosynthesis and metabolism of phenylalanine and tyrosine, metabolism of sulfur-containing amino acids, and oxidation of amino acids. The book is a valuable reference for chemists and researchers interested in enzymology.

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