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Elsevier

Books in Life sciences

  • Biomechanics and Related Bio-Engineering Topics

    Proceedings of a Symposium Held in Glasgow, September 1964
    • 1st Edition
    • R. M. Kenedi
    • English

  • Lymphokines

    A Forum for Immunoregulatory Cell Products
    • 1st Edition
    • Edgar Pick
    • English
    Lymphokines: A Forum for Immunoregulatory Cell Products deals with immunoregulatory cell products that produce lymphokines. Topics covered include the purification and characterization of transfer factor; activation of cytotoxicity and/or suppressor activity in murine macrophages by lymphokines, lipopolysaccharide, and polyinosinic-polycyt... acid; and the role of clotting processes in the action of lymphokines on macrophages. A comparison of the immune-modulating effects of interferon and interferon inducers is also presented. Comprised of 13 chapters, this volume begins with a discussion on transfer factor and its ability to react specifically with antigens. The clinical uses of transfer factor are considered with special emphasis on its value as a prophylactic agent. The reader is then introduced to the subject of T cell regulation of the immunoglobulin E (IgE) response via potentiating and suppressor lymphokines, together with the possible clinical application of IgE suppressive factors in the treatment of atopic diseases. Subsequent chapters examine the evidence in favor of the existence of T cell-derived polyclonal B cell activator (PBA) playing a role in both normal antibody responses and autoimmune diseases; the role of suppressor T cells and the associated lymphokines in contact sensitivity in mice; and lymphokine action on macrophages. The book also analyzes the genetics of the response of human and mouse cells to interferons. This monograph will be helpful to practitioners and researchers in the fields of microbiology and immunology.

  • Joint Replacement Technology

    • 2nd Edition
    • Peter A. Revell
    • English
    This second edition of Joint Replacement Technology provides a thoroughly updated review of recent developments in joint replacement technology. Joint replacement is a standard treatment for joint degradation and has improved the quality of life of millions of patients. Collaboration between clinicians and researchers is critical to its continued success and to meet the rising expectations of patients and surgeons. Part one introduces the advances in joint replacement technology, tribological considerations and experiments, and immune and regenerative responses to joint replacements. Part two covers the materials and techniques used in joint replacement. The advantages and disadvantages of different metals are explained here, as well as the use of ceramics. This section also addresses challenges in joint bearing surfaces, design, and cementless fixation techniques. Biological and mechanical issues are considered in part three, including healing responses to implants and biological causes of prosthetic joint failure, and a new chapter on imaging of joint prostheses. Each chapter in part four describes the clinical challenges of replacing specific joints, with specific focus on hip, knee, intervertebral disc joint, shoulder arthroplasty, elbow arthroplasty, and pyrocarbon small joint arthroplasty. Thanks to its widespread collaboration and international contributors, Joint Replacement Technology is useful for materials scientists and engineers in both academia and biomedical industry. Chemists, clinicians, and other researchers in this area will also find it invaluable.

  • Tissue Engineering Using Ceramics and Polymers

    • 2nd Edition
    • Aldo R. Boccaccini + 1 more
    • English
    The second edition of Tissue Engineering Using Ceramics and Polymers comprehensively reviews the latest advances in this area rapidly evolving area of biomaterials science. Part one considers the biomaterials used for tissue engineering. It introduces the properties and processing of bioactive ceramics and glasses, as well as polymeric biomaterials, particularly biodegradable polymer phase nanocomposites. Part two reviews the advances in techniques for processing, characterization, and modeling of materials. The topics covered range from nanoscale design in biomineralization strategies for bone tissue engineering to microscopy techniques for characterizing cells to materials for perfusion bioreactors. Further, carrier systems and biosensors in biomedical applications are considered. Finally, part three looks at the specific types of tissue and organ regeneration, with chapters concerning kidney, bladder, peripheral nerve, small intestine, skeletal muscle, cartilage, liver, and myocardial tissue engineering. Important developments in collagen-based tubular constructs, bioceramic nanoparticles, and multifunctional scaffolds for tissue engineering and drug delivery are also explained. Tissue Engineering Using Ceramics and Polymers is a valuable reference tool for both academic researchers and scientists involved in biomaterials or tissue engineering, including the areas of bone and soft-tissue reconstruction and repair, and organ regeneration.

  • Biomaterials for Bone Regeneration

    Novel Techniques and Applications
    • 1st Edition
    • P. Dubruel + 1 more
    • English
    Novel Biomaterials for Bone Regeneration provides a comprehensive review of currently available biomaterials and how they can be applied in bone regeneration. In recent decades, there has been a shift from the idea of using biomaterials as passive substitutes for damaged bones towards the concept of biomaterials as aids for the regeneration of a host's own bone tissue. This has generated an important field of research and a range of technological developments. Part one of this book discusses a wide range of materials, including calcium phosphate cements, hydrogels, biopolymers, synthetic polymers, and shape memory polymers. Part two then turns to the processing and surface modification of biomaterials, as well as how biomaterials can be evaluated both for their mechanical properties and for immunocompatibility with the host. Finally, part three covers a variety of cellular approaches, and production and delivery of biomaterials for bone regeneration. Chapters also consider the potential of electromagnetic and ultrasonic stimulation of biomaterials to aid in the regenerative process. Novel Biomaterials for Bone Regeneration represents an important resource for academics, clinicians, and industry professionals working in the area of biomedical materials, providing them with both an overview of the current state-of-the-art, and an indication of potential future developments.

  • Mouse Models of the Nuclear Envelopathies and Related Diseases

    • 1st Edition
    • Volume 109
    • English
    Volume 109 of Current Topics in Developmental Biology covers mouse models of the nuclear envelopathies and related diseases, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as mouse models neurodegenerative diseases including Parkinson’s and dystonia, muscle ageing and sarcopenia, cardiac failure and repair, ageing and prospects lifespan extension, lipodystrophy and the significance in fat regulation, also identifying developmental mutations in mammals and nuclear envelope and LINC complex in disease.

  • The Stimulated Brain

    Cognitive Enhancement Using Non-Invasive Brain Stimulation
    • 1st Edition
    • Roi Cohen Kadosh
    • English
    The Stimulated Brain—which garnered an Honorable Mention for Biomedicine & Neuroscience at the 2015 PROSE Awards from the Association of American Publishers—presents the first integration of findings on brain stimulation from different research fields with a primary focus on Transcranial Electrical Stimulation (tES), one of the most frequently used noninvasive stimulation methods. The last decade has witnessed a significant increase in the amount of research exploring how noninvasive brain stimulation can not only modulate but also enhance cognition and brain functions. However, although Transcranial Magnetic Stimulation (TMS) and particularly tES have the potential to become more widely applicable techniques (as they come with none of the risks associated with deep brain stimulation) the reference literature on these neurotechnologies has been sparse. This resource provides a broad survey of current knowledge, and also marks future directions in cognitive and neuro-enhancement. It expands our understanding of basic research findings from animals and humans, including clear translational benefits for applied research and the therapeutic use of noninvasive brain stimulation methods. The book's coverage includes a primer that paves the way to a more advanced knowledge of tES and its physiological basis; current research findings on cognitive and neuro-enhancement in animals and typical and atypical human populations, such as neurological patients; and discussions of future directions, including specific neuroethical issues and pathways for collaboration and entrepreneurialism. The Stimulated Brain is the first book to provide a comprehensive understanding of different aspects of noninvasive brain stimulation that are critical for scientists, clinicians, and those who are interested in “stimulating their minds” by exploring this fascinating field of research.

  • Wine Science

    Principles and Applications
    • 4th Edition
    • Ronald S. Jackson
    • English
    Wine Science, Fourth Edition, covers the three pillars of wine science: grape culture, wine production, and sensory evaluation. It discusses grape anatomy, physiology and evolution, wine geography, wine and health, and the scientific basis of food and wine combinations. It also covers topics not found in other enology or viticulture texts, including details on cork and oak, specialized wine making procedures, and historical origins of procedures. New to this edition are expanded coverage on micro-oxidation and the cool prefermentative maceration of red grapes; the nature of the weak fixation of aromatic compounds in wine – and the significance of their release upon bottle opening; new insights into flavor modification post bottle; the shelf-life of wine as part of wine aging; and winery wastewater management. Updated topics include precision viticulture, including GPS potentialities, organic matter in soil, grapevine pests and disease, and the history of wine production technology. This book is a valuable resource for grape growers, fermentation technologists; students of enology and viticulture, enologists, and viticulturalists.

  • Toxicological Survey of African Medicinal Plants

    • 1st Edition
    • Victor Kuete
    • English
    Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 121
    • Kenneth D. Tew + 1 more
    • English
    Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics.

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