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    • G Protein Coupled Receptors

      • 1st Edition
      • Volume 521
      • January 24, 2013
      • English
      • Hardback
        9 7 8 0 1 2 3 9 1 8 6 2 8
      • eBook
        9 7 8 0 1 2 3 9 1 8 7 3 4
      This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers G protein coupled receptors and includes chapters on such topics as G protein-coupled receptor trafficking motifs, structure-based virtual screening, and automation-friendly high throughput assays for identification of pharmacoperone drugs.

    • Fish Physiology: Euryhaline Fishes

      • 1st Edition
      • Volume 32
      • January 11, 2013
      • Stephen D. McCormick + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 6 9 5 1 4
      • eBook
        9 7 8 0 1 2 3 9 7 2 3 2 3
      The need for ion and water homeostasis is common to all life. For fish, ion and water homeostasis is an especially important challenge because they live in direct contact with water and because of the large variation in the salt content of natural waters (varying by over 5 orders of magnitude). Most fish are stenohaline and are unable to move between freshwater and seawater. Remarkably, some fishes are capable of life in both freshwater and seawater. These euryhaline fishes constitute an estimated 3 to 5% of all fish species. Euryhaline fishes represent some of the most iconic and interesting of all fish species, from salmon and sturgeon that make epic migrations to intertidal mudskippers that contend with daily salinity changes. With the advent of global climate change and increasing sea levels, understanding the environmental physiology of euryhaline species is critical for environmental management and any mitigative measures. This volume will provide the first integrative review of euryhalinity in fish. There is no other book that focuses on fish that have the capacity to move between freshwater and seawater. The different challenges of salt and water balance in different habitats have led to different physiological controls and regulation, which heretofore has not been reviewed in a single volume.

    • Immunopharmacology

      • 1st Edition
      • Volume 66
      • February 18, 2013
      • David J Webb
      • English
      • Hardback
        9 7 8 0 1 2 4 0 4 7 1 7 4
      • Paperback
        9 7 8 0 3 2 3 2 8 2 8 0 2
      • eBook
        9 7 8 0 1 2 4 0 5 1 8 4 3
      This new volume of Advances in Pharmacology explores the current state of Alzheimer's disease research and therapeutics. Chapters cover such topics as the B cell targeted therapies, Lymphotoxin family receptors in inflammation, and allergic inflammation and thymic stromal lymphopoietin. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

    • Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome

      • 1st Edition
      • Volume 112
      • November 27, 2013
      • English
      • Hardback
        9 7 8 0 1 2 4 1 1 5 4 6 0
      • eBook
        9 7 8 0 1 2 4 1 1 5 6 1 3
      This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments.

    • Research Methods in Biomineralization Science

      • 1st Edition
      • Volume 532
      • October 31, 2013
      • English
      • Hardback
        9 7 8 0 1 2 4 1 6 6 1 7 2
      • eBook
        9 7 8 0 1 2 4 1 6 6 5 5 4
      This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in biomineralization science, and includes sections on such topics as determining solution chemistry, structure and nucleation; probing structure and dynamics at surfaces; and interfaces mapping biomineral and morphology and ultrastructure.

    • Protides of the Biological Fluids

      • 1st Edition
      • September 3, 2013
      • H. Peeters
      • English
      • eBook
        9 7 8 1 4 8 3 1 5 3 6 7 4
      Protides of the Biological Fluids: Proceedings of the 25th Colloquium, Brugge, 1977 focuses on the structure, metabolism, transformations, and reactions of protides of biological fluids. The selection first takes a look at the structure and metabolism of plasma lipoproteins, including phosphatidylinositol exchange protein from bovine brain; structural integrity of the mitochondrial adenine nucleotide carrier; and reassembly of the monosaccharide transport system of the human erythrocyte in black lipid membranes. The book then discusses species and dietary effects on lipoprotein apoprotein metabolism in vivo; transfer of surface and core lipids of a lipoprotein from plasma into aortic wall; and pathophysiological implications of hyperlipoproteinemia... The text focuses on lipoproteins of human peripheral lymph, portacaval shunt and lipid metabolism, and low density lipoprotein catabolism in the liver. The methods and results of experiments are presented. The book also discusses the effects of dietary cholesterol on serum lipoprotein in human; long-term effects of physical training on blood lipids and lipoproteins in primary hyperlipoproteinemia... and effects of clofibrate on plasma proteins in subjects with hypertriglyceridemia... The selection is a vital source of data for readers wanting to study the protides of biological fluids.

    • Advances in Applied Microbiology

      • 1st Edition
      • Volume 84
      • June 5, 2013
      • English
      • eBook
        9 7 8 0 1 2 4 0 7 8 0 0 0
      Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology. Recent areas covered include bacterial diversity in the human gut, protozoan grazing of freshwater biofilms, metals in yeast fermentation processes and the interpretation of host-pathogen dialogue through microarrays. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome. Impact factor for 2011: 5.233

    • Emery and Rimoin's Essential Medical Genetics

      • 1st Edition
      • April 23, 2013
      • David L. Rimoin + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 4 0 7 2 4 0 4
      • eBook
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      • eBook
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      For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics has provided the ultimate source for practicing clinicians to learn how the study of genetics can be integrated into practice. Developed in parallel to the sixth edition, and featuring 174 original contributions from the many authors of the full set, this one volume work expertly condenses and synthesizes the most clinically relevant content, for convenient desk reference.Helping to bridge the gap between high-level molecular genetics and individual application, it follows the multi-volume set in encompassing scientific fundamentals, full spectrum discussion of major inherited disorders, and actionable therapies. Clinically oriented information is supported by concise descriptions of the principles of genetics, research approaches, and analytics to embrace the evolving population of students, researchers, and practitioners who are integrating their work to provide advanced diagnosis, prevention and treatment of human disease.This print volume is complemented and enhanced with online access to the complete text, online-only references, and high quality illustrations on www.expertconsult.co...

    • G Protein Coupled Receptors

      • 1st Edition
      • Volume 522
      • January 28, 2013
      • English
      • Hardback
        9 7 8 0 1 2 4 0 7 8 6 5 9
      • eBook
        9 7 8 0 1 2 4 0 7 9 4 4 1
      This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers G protein coupled receptors, and includes chapters on such topics as GPCR modelling, interactions with other molecules, virtual screening and GPCR activation.

    • Encyclopedia of Sleep

      • 1st Edition
      • January 3, 2013
      • Clete Kushida
      • English
      • Hardback
        9 7 8 0 1 2 3 7 8 6 1 0 4
      • eBook
        9 7 8 0 1 2 3 7 8 6 1 1 1
      In a world of 24-hour media saturation, sleep has become an increasingly fraught enterprise. The award-winning four-volume Encyclopedia of Sleep, Four Volume Set is the largest reference, either online or in print, on the subject of sleep. Written to be useful for the novice and the established researcher and clinician, Topic areas will include sleep across the life cycle and in other species, sleep and women, sleep and the elderly, pediatric sleep, sleep deprivation and loss, sleep mechanisms, sleep physiology and pathophysiology, sleep disorders, neurobiology, chronobiology, pharmacology, and impact of other disorders on sleep. Recognizing the many fields that are connected to sleep science, the editorial team has been carefully chosen to do justice to this highly interdisciplinary field of study. The steady growth of researchers and clinicians in the sleep field attests to the continued interest in the scientific study of sleep and the management of patients with sleep disorders, and anyone involved in this exciting field should find this work to be an invaluable reference.

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