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Elsevier

Books in Life sciences

  • Biological and Biochemical Oscillators

    • 1st Edition
    • Britton Chance + 2 more
    • English
    Biological and Biochemical Oscillators compiles papers on biochemical and biological oscillators from a theoretical and experimental standpoint. This book discusses the oscillatory behavior, excitability, and propagation phenomena on membranes and membrane-like interfaces; two-dimensional analysis of chemical oscillators; and chemiluminescence in oscillatory oxidation reactions catalyzed. The problems associated with the computer simulation of oscillating systems; mechanism of single-frequency glycolytic oscillations; excitation wave propagation during heart fibrillation; and biochemical cycle of excitation are also elaborated. This compilation likewise covers the physiological rhythms in Saccharomyces cerevisiae populations; integral and indissociable property of eukaryotic gene-action systems; and role of actidione in the temperature jump response of the circadian rhythm in Euglena gracilis. This publication is valuable to biochemists interested in biochemical and biological oscillations.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 21
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 21 covers several significant and emerging areas in lipid metabolism, including apolipoprotein metabolism and leukotrienes. This book discusses the role of fat in the functioning of the immune system. Organized into eight chapters, this volume begins with an overview of the metabolism of apolipoprotein B, which is the principal protein of chylomicrons, very low density, and low density lipoprotein. This text then describes the metabolism, biosynthesis, and pharmacology of leukotrienes. Other chapters consider the relation of lipids to immunology and explain the roles played by lipids in the structure and function of yeast membrane. This book discusses as well the general importance in the plant kingdom and the place of some carotenoids in human biology. The final chapter deals with the influence of proteins on configuration and function of reconstituted lipid membranes. This book is a valuable resource for biologists, chemists, biochemists, scientists, and research workers.

  • Immunobiology of the Macrophage

    • 1st Edition
    • David S. Nelson
    • English
    Immunobiology of the Macrophage presents an account of the state of knowledge of the immunobiology of the macrophage. The book’s contributors—immunol... of diverse scientific and geographic backgrounds—have been encouraged to give personal accounts of developments in their special fields of interest as well as critical surveys of the backgrounds leading to these developments. The book begins with a study on the functions of macrophages in the initiation and regulation of antibody responses in vitro. This is followed by separate chapters on topics such as the role of macrophages in making antigen more immunogenic and less tolerogenic; functional distinctions between macrophages at different sites; and the role of the macrophage in antigen recognition by T lymphocytes. Subsequent chapters examine interactions between macrophages and lymphocytes in the production of interferon and other mediators of cellular immunity; macrophage cell lines and their uses in immunobiology; and cytotoxic macrophages in allograft rejection.

  • Protein Turnover and Lysosome Function

    • 1st Edition
    • Harold L. Segal + 1 more
    • English
    Protein Turnover and Lysosome Function comprises the proceedings of a symposium under the same title held at the State University of New York at Buffalo on August 21-26, 1977. The book discusses mechanisms of protein turnover, as well as the identification and characterization of intracellular proteases. The text also describes the internalization of macromolecules into the intracellular digestive system; the types of specificity entailed; and the fate of the membrane material involved in the vacuolization process. Biochemists, pathologists, cell biologists, molecular biologists, and physiologists will find the book invaluable.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 23
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 23 provides information pertinent to mammalian as well as plant metabolism. This book presents important data on apoproteins, which may offer a foothold for further probes of the genetics underlying increased susceptibility to ischemic heart disease. Organized into seven chapters, this volume begins with an overview of the molecular biology of human apolipoproteins B and E. This text then explains the lipid metabolism of dermatophytes and describes their lipid composition and how it may be modulated. Other chapters consider the function, distribution, and biosynthesis of the sterols of fungi and examine the influences of fungal sterols on membrane fluidity. This book discusses as well the biosynthesis and degradation of platelet-activating factor (PAF) as well as its physiological function. The final chapter deals with one specific area of PAF activity, namely, renal processes. This book is a valuable resource for biologist, biochemists, chemists, and clinicians.

  • Bacterial Metabolism

    • 2nd Edition
    • H. W. Doelle
    • English
    Bacterial Metabolism, Second Edition describes microbial systematics and microbial chemistry and focuses on catabolic events. This book deals with the progress made in bacterial metabolism that includes data on regulatory mechanisms; comparison of bacterial growth kinetics with enzyme kinetics; aerobic amino acid catabolism; and the glucose transport mechanism. This text also emphasizes the development of photosynthetic phosphorylation in the different bacterial families. This book explains anaerobic respiration and carbohydrate metabolism—glucose, fructose, lactose, mannose, allose, and sorbitol. This text then describes aerobic respiration including the "Nitroso" and "Nitro" groups of genera, and the Knallgas bacteria, which use the reaction between molecular hydrogen and molecular oxygen as their source of energy. This book also explains the microbial transformation of iron as caused by either specific organisms (e.g. Ferrobacillus ferrooxidans) or nonspecific organisms. This selection also explains the process of fermentation by Enterobacteriaceae, lactic acid bacteria, and proteolytic clostridia. This text can be valuable for microchemists, microbiologists, students, and academicians whose disciplines are in biological chemistry and cellular biology.

  • Molecular Approaches to Neurobiology

    • 1st Edition
    • Ian R. Brown
    • English
    Molecular Approaches to Neurobiology deals with molecular approaches to the analysis of the nervous system. This book surveys the current state of knowledge in a number of areas of molecular neurobiology that includes the subcellular level of chromatin structure, complexity of RNA synthesis, role of hormones in cell differentiation, and molecular correlates between neuropeptides and behavior. A comprehensive review of procedures for the isolation of specific brain cells and their experimental use is also provided at the end of this text. This publication is useful to those working in the field of neurochemistry and those engaged in morphological and physiological approaches to the analysis of the nervous system, as well as molecular biologists and biochemists working with non-neural tissues.

  • Horizons of Bioenergetics

    Proceedings of a Symposium held at Bloomington, Indiana October 12-15, 1970
    • 1st Edition
    • Anthony San Pietro + 1 more
    • English
    Horizons of Bioenergetics provides information pertinent to the fundamental aspects of bioenergetics. This book covers a variety of topics, including oxidative phosphorylation, energy conservation, ATP formation, metabolic regulation, glycolysis, and photosynthesis efficiency. Organized into five sessions encompassing 23 chapters, this book begins with an overview of the major landmarks in biochemical evolution that are most relevant to the discussion on bioenergetics. This text then reviews the knowledge about ATP generation by substrate level phosphorylation by anaerobic bacteria that ferment organic compounds. Other chapters consider the resolution and reconstitution of oxidative phosphorylation. This book discusses as well another energy-requiring activity associated with electron transport in mitochondria that may take primacy over oxidative phosphorylation. The final chapter deals with the possibility that conformational change can induce major shifts in electro-chemical potential and provide a mechanism for energy storage and conversion. This book is a valuable resource for biochemists, scientists, and research workers.

  • Experimental Manipulation of Gene Expression

    • 1st Edition
    • Masayori Inouye
    • English
    Experimental Manipulation of Gene Expression discusses a wide range of host systems in which to clone and express a gene of interest. The aims are for readers to quickly learn the versatility of the systems and obtain an overview of the technology involved in the manipulation of gene expression. Furthermore, it is hoped that the reader will learn enough from the various approaches to be able to develop systems and to arrange for a gene of particular interest to express in a particular system. The book opens with a chapter on the design and construction of a plasmid vector system used to achieve high-level expression of a particular phage regulatory protein normally found in minute amounts in a phage-infected bacterial cell. This is followed by separate chapters on topics such as high-level expression vectors that utilize efficient Escherichia coli lipoprotein promoter as well as various other portions of the lipoprotein gene Ipp; DNA cloning systems for streptomycetes; and the design and application of vectors for high-level, inducible synthesis of the product of a cloned gene in yeast.

  • Advances in Steroid Biochemistry and Pharmacology

    • 1st Edition
    • M. H. Briggs + 1 more
    • English
    Advances in Steroid Biochemistry and Pharmacology, Volume 4 provides information pertinent to the fundamental aspects of steroid biochemistry and pharmacology. This book covers a variety of topics, including cellular biochemistry, pituitary hormones, corticosteroids, and steroid hormones. Organized into seven chapters, this volume begins with an overview of the potential effects of steroids on cellular biochemistry. This text then examines the development of sleep-monitoring methods, together with methods of plasma sampling that enable very frequent specimen to be taken without disturbing the subject. Other chapters consider the usefulness of sleep-related growth hormone release in diagnosis in both children and adult. This book discusses as well the versatile effect of corticosteroids on the cellular components of the connective tissue. The final chapter deals with the functioning of the adrenal cortex and its control by adrenocorticotropic hormone (ACTH). This book is a valuable resource for biochemists, histochemists, biologists, pharmacologists, clinicians, and experimental endocrinologists.

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