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Books in Life sciences

    • Cardiac Regeneration and Repair

      • 1st Edition
      • January 22, 2014
      • Ren-Ke Li + 1 more
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 5 6 0 5
      • Hardback
        9 7 8 0 8 5 7 0 9 6 5 9 3
      • eBook
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      Cardiac Regeneration and Repair, Volume Two reviews the use of biomaterials, alone or combined with cell therapy, in providing tissue-engineered constructs to repair the injured heart and prevent or reverse heart failure. Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy for restoring ventricular function and generating stem cell-modified intravascular stents. Part two focuses on tissue engineering for cardiac repair, including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodeling, including chapters highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels. Cardiac Regeneration and Repair, Volume Two is complemented by an initial volume covering pathology and therapies. Together, the two volumes of Cardiac Regeneration and Repair provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials.
    • Vectors

      • 1st Edition
      • May 20, 2014
      • Raymond L. Rodriguez + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 0 9 4 2 8
      • eBook
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      Vectors: A Survey of Molecular Cloning Vectors and Their Uses focuses on the functions of molecular cloning vectors. The book first discusses bacterial plasmid pBR322. Topics include criteria for plasmid vector design, construction and structure, transcriptional signals, DNA replication, recombination, mobilization, and plasmid stability. The text also examines bacteriophage lambda cloning vectors; filamentous phages as cloning vectors; chimeric single-stranded DNA phage-plasmid cloning vectors; and phage-plasmid hybrid vectors. The selection discusses cosmids and plasmid positive selection vectors, including library and construction, cosmid rescue, and positive selection vectors using plasmid-encoded lethal function. The text also examines vectors for regulating expression of cloned DNA, including lambda promoters, secretion vectors, and protein fusion vectors. The book takes a look at vectors with adjustable copy numbers. Copy number and protein production; adjustable copy number vectors; future expression vectors; rate-limiting steps of protein production; and promoters and ribosome binding sites are explained. The text puts emphasis on vectors for the synthesis of specific RNAs in vitro and cloning vectors for gram-positive bacteria. The selection is a valuable source of data for readers interested in molecular cloning vectors.
    • Food Texture and Viscosity: Concept and Measurement

      • 1st Edition
      • June 28, 2014
      • Malcolm C. Bourne
      • English
      • Paperback
        9 7 8 0 1 2 3 9 4 2 5 7 9
      • eBook
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      Food Science and Technology: A Series of Monographs: Food Texture and Viscosity: Concept and Measurement focuses on the texture and viscosity of food and how these properties are measured. The publication first elaborates on texture, viscosity, and food, body-texture interactions, and principles of objective texture measurement. Topics include area and volume measuring instruments, chemical analysis, multiple variable instruments, soothing effect of mastication, reasons for masticating food, rheology and texture, and the rate of compression between the teeth. The book then examines the practice of objective texture measurement and viscosity and consistency, including the general equation for viscosity, methods for measuring viscosity, factors affecting viscosity, tensile testers, distance measuring measurements, and shear testing. The manuscript takes a look at the selection of a suitable test procedure and sensory methods of texture and viscosity measurement. Discussions focus on nonoral methods of sensory measurement; correlations between subjective and objective measurements; variations on the texture profile technique; and importance of sensory evaluation. The publication is a vital source of information for food experts and researchers interested in food texture and viscosity.
    • Membrane Proteins

      • 1st Edition
      • May 9, 2014
      • Peter Nicholls + 2 more
      • English
      • Paperback
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      • eBook
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      Membrane Proteins contains the proceedings of the 11th Meeting of the Federation of European Biochemical Societies, held in Copenhagen, Denmark in 1977. The meeting provided a forum for discussing progress that has been made in understanding membrane proteins. Topics covered range from hydrogen and electron transfer in mitochondria to energy-transferring systems as well as ATPases and hormone receptors. Comprised of 31 chapters, this volume begins by reporting the results of a study that examined the state of association of several important membrane proteins. The discussion then turns to future prospects for membrane structures; hydrogen and electron transfer in mitochondria; and the molecular mechanism of the respiratory chain proton pump. Subsequent chapters explore energy coupling in reconstituted segments of the respiratory chain; retinal-protein interaction in bacteriorhodopsin; the functional significance of protein-protein interactions in the sarcoplasmic reticulum; and the role of calcium in the action of insulin. This book will be of interest to biochemists.
    • Current Topics in Bioenergetics

      • 1st Edition
      • June 28, 2014
      • D. Rao Sanadi + 1 more
      • English
      • Paperback
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      • eBook
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      Current Topics in Bioenergetics, Volume 5 provides information pertinent to the molecular properties of purified enzymes and defined reactions. This book presents the development in the research on oxidative phosphorylation. Organized into nine chapters, this volume begins with an overview of the contributions to the knowledge of membrane structure based on X-ray diffraction analysis. This text then examines the reactions of chlorophyll in model systems and the luminescence linked with light absorptions, which relate to the early events in photosynthesis. Other chapters relate spectroscopic and EPR measurements to redox changes linked with energy coupling in the mitochondrial electron carriers. This book discusses as well the role of soluble proteins in the energy transfer process of oxidative phosphorylation. The final chapter deals with the chemical and structural properties of the photoreceptors in the visual process. This book is a valuable resource for biophysicists, physiologists, biologists, biochemists, physical chemists, and research workers.
    • Methods in Virology

      • 1st Edition
      • June 28, 2014
      • Karl Maramorosch + 1 more
      • English
      • Paperback
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      • eBook
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      Methods in Virology, Volume VII focuses on the methods used in virology, including radioimmunoassays, microscopy, hybridization, and mutagenesis. The selection first elaborates on monoclonal antibody techniques applied to viruses; competition radioimmunoassays for characterization of antibody reactions to viral antigens; and enzyme immunosorbent assays in plant virology. Discussions focus on the principles of enzyme immunosorbent assay, choice of enzyme and preparation of conjugate, determination of immunoglobulin class, and maintenance and specificity testing of hybridomas. The text then elaborates on electron microscopy for the identification of plant viruses in in vitro preparations and cloning and expression of viral antigens in Escherichia coli and other microorganisms, including influenza virus, expression of foreign coding sequences in Escherichia coli, hepatitis B virus, electron microscope, immunoelectron microscopy, and imaging of nucleic acids. The manuscript takes a look at the detection and characterization of subgenomic RNA in plant viruses; exploring the gene organization of baculoviruses; and spot hybridization for detection of viroids and viruses. Topics include application to viral diseases, mapping mutuations of baculoviruses, transcriptional mapping of baculovirus genomes, and genetic mapping by blot hybridization. The selection is a valuable source of information for researchers interested in the methods employed in virology.
    • The Oxygen Evolving System of Photosynthesis

      • 1st Edition
      • June 28, 2014
      • Yorinao Inoue + 2 more
      • English
      • Paperback
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      • eBook
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      The Oxygen Evolving System of Photosynthesis documents the proceedings of an international symposium entitled ""Photosynthetic Water Oxidation and Photosystem II Photochemistry,"" held at The Institute of Physical and Chemical Research (RIKEN), Wako, Saitama, Japan, 15-17 March 1983. Several other papers from authorities in this field are also included. This book provides in a systematic fashion the most current thoughts and insights into the field of photosynthetic oxygen evolution. The volume contains 46 chapters organized into five parts. Part I deals with the subunit structure of photosystem II reaction center pigment proteins and the charge separation (generation of positive and negative charges, P680+ and Pheo-). Part II examines the components and their function on the donor side. Part III discusses the biochemistry of the water oxidation enzyme system, polypeptide composition, and functional reconstitution. Part IV take up the functions of chloride and bicarbonate in electron transport and the mechanism of photoactivation in latent or Tris-inactivated chloroplasts. Part V discusses the fate of reducing equivalents going through the two-electron gate mechanism, together with the biochemistry of the quinone components on the acceptor side.
    • Advances in Lipid Research

      • 1st Edition
      • Volume 21
      • June 28, 2014
      • Rodolfo Paoletti + 1 more
      • English
      • Paperback
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      • eBook
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      Advances in Lipid Research, Volume 21 covers several significant and emerging areas in lipid metabolism, including apolipoprotein metabolism and leukotrienes. This book discusses the role of fat in the functioning of the immune system. Organized into eight chapters, this volume begins with an overview of the metabolism of apolipoprotein B, which is the principal protein of chylomicrons, very low density, and low density lipoprotein. This text then describes the metabolism, biosynthesis, and pharmacology of leukotrienes. Other chapters consider the relation of lipids to immunology and explain the roles played by lipids in the structure and function of yeast membrane. This book discusses as well the general importance in the plant kingdom and the place of some carotenoids in human biology. The final chapter deals with the influence of proteins on configuration and function of reconstituted lipid membranes. This book is a valuable resource for biologists, chemists, biochemists, scientists, and research workers.
    • Microbial Biodegradation and Bioremediation

      • 1st Edition
      • June 21, 2014
      • Surajit Das
      • English
      • Paperback
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      Microbial Biodegradation and Bioremediation brings together experts in relevant fields to describe the successful application of microbes and their derivatives for bioremediation of potentially toxic and relatively novel compounds. This single-source reference encompasses all categories of pollutants and their applications in a convenient, comprehensive package. Our natural biodiversity and environment is in danger due to the release of continuously emerging potential pollutants by anthropogenic activities. Though many attempts have been made to eradicate and remediate these noxious elements, every day thousands of xenobiotics of relatively new entities emerge, thus worsening the situation. Primitive microorganisms are highly adaptable to toxic environments, and can reduce the load of toxic elements by their successful transformation and remediation.
    • Structure–Function Relationships of Proteolytic Enzymes

      • 1st Edition
      • May 10, 2014
      • P. Desnuelle + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 8 1 0 4
      • eBook
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      Structure–Function Relationships of Proteolytic Enzymes provides information pertinent to the fundamental aspects of proteolytic enzymes. This book presents the historical role of proteolytic enzyme as a group in protein and enzyme chemistry. Organized into 23 chapters, this book begins with an overview of the results obtained from investigation on the chymotrypsinogens of porcine origin. This text then examines the differences of amino acid sequence between chymotrypsin, trypsin, and elastase that affect the substrate binding site, which reflect the specificity differences between these enzymes. Other chapters consider the kinetic parameters related to the trypsin-catalyzed hydrolysis of several model peptides. This book discusses as well the acetylation of trypsin, which result in functional consequences varying from complete inactivation to promotion of activity. The final chapter deals with the physical properties of stem bromelain in comparison with the data for three other sulfhydryl proteases of plant origin. This book is a valuable resource for enzymologists, microbiologists, and biochemists.