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Books in Life sciences

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    • Hormonal Proteins and Peptides

      • 1st Edition
      • May 12, 2014
      • Choh Hao Li
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 2 6 8 2
      • eBook
        9 7 8 1 4 8 3 2 5 7 9 6 9
      Hormonal Proteins and Peptides, Volume I reviews extensively the knowledge on the biology and chemistry of the protein and peptide hormones. This book presents the structures of the various protein and peptide hormones. Organized into five chapters, this volume begins with an overview of the chemistry of several hormonal glycoproteins. This text then presents the research on the purification and chemistry of thyroid-stimulating hormone (TSH). Other chapters consider the study of ovine interstitial cell-stimulating hormone, and concentrate to some extent on the very closely related bovine species. This book discusses as well some aspects of the biology of the pituitary interstitial cell-stimulating hormone or luteinizing hormone in mammalian species. The final chapter deals with the correlation of the primary structure with function for a better understanding of the mechanism of action of the hormone at a molecular level. This book is a valuable resource for biologists, biochemists, and research workers.

    • Immunological Methods

      • 1st Edition
      • May 12, 2014
      • Ivan Lefkovits + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 6 9 6 3 4
      Immunological Methods, Volume III provides information pertinent to the fundamental aspects of immunological methods. This book presents recombinant DNA technology as applied to immunology. Organized into 25 chapters, this volume begins with an overview of the major histocompatibility complex. This text then examines the use of monoclonal antibodies in the identification of lymphocyte membrane antigens and explains the use of monoclonal antibodies in histocompatibility typing. Other chapters consider the methods in two-dimensional electrophoretic analysis of proteins and another to lymphokines that support B cells. This book discusses as well the production and expansion of cloned B and T cell lines and hybridomas. The final chapter deals with the sophisticated methodology used with particular animal species, namely, birds, sheep, and amphibians to probe specific immunological questions. This book is a valuable resource for immunologists and investigators with extensive experience in using immunological methods. Protein chemists and biologists will also find this book useful.

    • Calcium Physiology

      • 1st Edition
      • May 12, 2014
      • C. L. Comar + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 5 9 8 2 6
      Mineral Metabolism, Volume III: Calcium Physiology focuses on the processes, reactions, and approaches involved in calcium metabolism and study of bones. The selection first underscores the measurements and models of skeletal metabolism and advances in the physical biology of bone and other hard tissues, including measurements and concepts, composition and structure of bone minerals, and dynamic studies of bone minerals. The text then takes a look at calcium and striated muscle and renal excretion of alkaline earths. Topics include physicochemical state of alkaline earth cations in plasma and urine, effects of drugs, renal diseases, calcium and contractile proteins, resting potential and action potential, calcium and muscle contraction, and coupling of excitation and energy synthesis. The book examines the aspects of intestinal absorption of calcium, with special reference to vitamin D, as well as the physiological mechanism of the intestinal absorption of calcium; effect of other nutritional and physiological factors on calcium absorption; and structure of the intestinal epithelial cell. The selection is a dependable source material for physiologists and readers interested to pursue research on calcium physiology.

    • Biochemistry of Glucuronic Acid

      • 1st Edition
      • May 12, 2014
      • Neal E. Artz + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 1 2 0 1 2
      • eBook
        9 7 8 1 4 8 3 2 2 5 4 4 9
      Biochemistry of Glucuronic Acid provides a comprehensive study of the metabolic importance of glucoronic acid. This book presents the physiological role of glucoronic acid as a detoxifying agent. Organized into four chapters, this book begins with an overview of the naphthoresorcinol test, which is the most accurate colorimetric method for the determination of glucoronic acid. This text then explores the occurrence of glucoronic acid, which is found in many plant gums, in oxycellulose, as well as in conjugated form in low concentrations in normal blood and urine. Other chapters consider the mechanisms for the formation of glucoronic acid in the body. The final chapter deals with detoxication as any chemical change occurring in the body that brings about the conversion of a foreign compound of known structure to a derivative that is excreted in the urine. This book is a valuable resource for biochemists.

    • Chemical Determinations

      • 1st Edition
      • May 12, 2014
      • Ralph I. Dorfman
      • English
      • eBook
        9 7 8 1 4 8 3 2 7 2 7 8 8
      Chemical Determinations is a collection of papers that discusses chemical methods used in hormone investigation. One paper explains the physicochemical procedures used to separate estrogens from interfering material which leads to the possible determination of small amounts of hormones in biological fluids. One approach is through simpler methods for routine use, designed principally for the determination of estrogens in urine and in plasma. Another way is through more elaborate methods, designed to establish the presence and identity of various estrogens in small numbers of biological samples. Another paper explains the methods for the analysis of 17-ketosteroids of blood and urine, and a method for the assay of testosterone in plasma which correlates with the state of virilism of an individual. One paper describes the techniques utilized for extraction, preliminary purification, isolation, and quantitative estimation of progesterone. Another paper reviews the occurrence of pregnanetriolone (an inactive urinary metabolite), the significance of its estimation as an aid in differential diagnosis, the methods of estimation, as well as the metabolic pathways leading to the excretion of pregnanetriolone and related steroids. The collection is suitable for researchers, scientists, medical practitioners, or academicians involved in endocrinology, metabolism, and bio-research.

    • Physical and Chemical Methods

      • 1st Edition
      • May 12, 2014
      • Curtis A. Williams + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 9 5 6 2
      • eBook
        9 7 8 1 4 8 3 2 2 2 9 9 8
      Methods in Immunology: Volume II, Physical and Chemical Methods is a collection of papers dealing with electrophoresis, analytical ultracentrifugation, dialysis, ultrafiltration, cellulose ion exchangers, and chromatographic separation of macromolecules on porous gels. Some papers explain the applications of radioisotopes, optical analysis, and chemical analysis of proteins, carbohydrates, lipids, and nucleic acid. One paper describes the theory of electro-migration. Factors such as electrical charge or frictional coefficients govern the rate of migration of charged particles in an electric field. The differences found in their velocities can be used to separate substances or analyze them. Mobility is a characteristic property of molecules and can also be influenced by the composition of the medium or solution. Dialysis separates solvents too large to diffuse through a barrier from smaller solutes; ultrafiltration (reverse osmosis) forces solvent and solutes up to a certain critical size through the barrier by a high pressure on one side. The book notes that the membrane never becomes plugged in dialysis because of some opposite movement of the solvent. Another paper points out that the significance of radioactive tracers in immunochemistry employed to identify and label macromolecules functioning as antigens and antibodies. The collection can prove valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in immunological research.

    • Evolving Genes and Proteins

      • 1st Edition
      • May 12, 2014
      • Vernon Bryson + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 0 5 9 5
      • eBook
        9 7 8 1 4 8 3 2 6 6 3 0 5
      Evolving Genes and Proteins covers the proceedings of the "Evolving Genes and Proteins" symposium, held at the Institute of Microbiology of Rutgers, The State University on September 17 and 18, 1964, with support from the National Science Foundation. The book focuses on the structural and functional features of proteins and nucleic acids. The selection first offers information on lysine biosynthesis and evolution, lipid patterns in the evolution of organisms, and evolution of heme and chlorophyll. Discussions focus on the evolution of the genes of the porphyrin biosynthetic chain, polyunsaturated fatty acids in plants and animals, and diagnostic radiocarbon tracers. The text then examines evolutionary divergence and convergence in proteins; evolution of hemoglobin in primates; and constancy and variability of protein structure in respiratory and viral proteins. The publication takes a look at the comparative aspects of the structure and function of phosphoglucomutase, evolution of dehydrogenases, and enzymatic homology and analogy in phylogeny. The text also ponders on the evolution of an enzyme, role of mutations in evolution, enzyme catalysis and color of light in bioluminescent reactions, and evolution of the lactose utilization gene system in enteric bacteria. The selection is a valuable reference for microbiologists and readers interested in the study of genes and proteins.

    • The Alkaloids

      • 1st Edition
      • May 12, 2014
      • R. H. F. Manske
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 8 5 6 5
      • eBook
        9 7 8 1 4 8 3 2 2 1 9 9 1
      The Alkaloids: Chemistry and Physiology, Volume X focuses on the structure of alkaloids. This book discusses the occurrence of glycoalkaloids and alkamines, jerveratrum alkaloids, and erythrophleum alkaloids containing a C-4 carbomethoxy group. The mass spectra of lycopodium alkaloids, alkaloids of the Calabar bean, and benzyltetrahydroisoq... alkaloids with three oxygenated substituents are also elaborated. This publication likewise covers the biogenesis of benzylisoquinoline alkaloids, simple indole bases, biogenesis of the picralima alkaloids, and stereochemistry of the uncarines. Other topics include plants and their contained alkaloids, lycodine and related alkaloids, and a-naphthaphenanthrid... alkaloids. This volume is suitable for chemists and specialists working in the field of alkaloid chemistry.

    • Glutathione

      • 1st Edition
      • May 12, 2014
      • S. Colowick + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 2 2 5 4
      • eBook
        9 7 8 1 4 8 3 2 6 1 5 0 8
      Glutathione: A Symposium covers the proceedings of the symposium held in Ridgefield, Connecticut in November 1953. The book focuses on the chemistry, characteristics, reactions, and properties of glutathione (GSH). The selection first offers information on mercaptans and disulfides, reactivity of the sulfhydryl group in GSH and related peptides, and chemistry and properties of GSH. Discussions focus on isolation and occurrence of GSH, properties of GSH, general chemistry of acidity, oxidation, and disulfides, and application to the structure of GSH. The text then examines thiol-thiolester complex formation, methods of GSH assay, and paper chromatography of GSH and its hydrolysis products. The publication takes a look at histochemical experiments on sulfhydryls and disulfides, enzymatic oxidation and reduction of GSH, and biosynthesis of GSH. Topics include synthesis of GSH from the constituent amino acids, enzymatic oxidation of GSH, and methods for demonstrating protein-bound sulfhydryl and disulfide groups in tissues. The selection is a dependable reference for researchers interested in the chemistry, reactions, and properties of glutathione.

    • Oxygenases

      • 1st Edition
      • May 12, 2014
      • Osamu Hayaishi
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 5 5 9 0
      • eBook
        9 7 8 1 4 8 3 2 6 3 5 2 6
      Oxygenases focuses on the processes, methodologies, technologies, and approaches involved in oxygenases, including its distribution in animals, plants, and microorganisms and its role in the metabolism of aromatic, cyclic, and aliphatic compounds. The selection first offers information on the history and scope of oxygenases, methodology of oxygen isotopes, and phenolytic oxygenases. Discussions focus on the separation and purification of compounds for isotopic analysis; general properties and mechanisms of action of oxygenases; physiological significance of oxygenases; dehydrogenases, oxidases, and oxygenases; and problems and restrictions in the use of oxygen-18. The text then examines aromatic hydroxylations, oxygenases in lipid and steroid metabolism, and bacterial oxidation of hydrocarbons. Topics include anaerobic oxidation of alkanes, involvement of molecular oxygen in hydrocarbon utilization, steroid hydroxylation mechanisms, oxygenases in the biosynthesis of steroid hormones, conversion of dopamine to norepinephrine, and general discussion of mechanism of aerobic hydroxylation reactions. The selection is a valuable reference for researchers interested in the process of oxygenases.

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