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    • Monoclonal Antibodies Against Bacteria

      • 1st Edition
      • May 10, 2014
      • Alberto J. L. Macario + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 3 0 3 0
      • eBook
        9 7 8 1 4 8 3 2 5 7 3 8 9
      Monoclonal Antibodies Against Bacteria, Volume II provides the basis for understanding new developments of practical importance in the health sciences within the area of microbiology and infectious diseases, focusing on advances made possible by monoclonal antibodies. This 12-chapter volume starts with the analysis of streptococcal antigens implicated in the causation of rheumatic fever and heart disease to find ways of inducing protective immunity. The next chapters deal with the detection of staphylococcal enterotoxins in foods and treatment of staphylococcal food poisoning, the classification of meningococcal isolates associated with meningitis and related disorders, and the immunology of brucellosis with emphasis on the problem of distinguishing antibrucella antibodies elicited by vaccination of cattle from antibodies elicited by infection. These topics are followed by discussions of the diagnostic and epidemiologic studies of legionellosis; the identification of antigens in gram-negative bacteria; and the development of means to study and control infections by Pseudomonas in cystic fibrosis and other pathologic conditions. Other chapters explore the analysis of toxigenicity and neutralization of botulinum toxin, the pathogenetic role of Escherichia coli's pili, and study of its antigens to understand regulatory networks of the immune system involving antiidiotypic antibodies. The remaining chapters consider the elucidation of antigenic mosaics of archaebacteria and identification of their molecular signatures in their ecological niches and other life forms. These chapters also look into the combination of bacterial genetics with hybridoma technology for elucidating structure-function relationships in membrane molecules, as well as the strategies, methods, quality control, and other practical aspects connected with industrial production of monoclonal antibodies against bacteria. This book will prove useful to internists, pediatricians, surgeons, dentists, veterinarians, clinical pathologists, and laboratory technologists.

    • Clinical Immunobiology

      • 1st Edition
      • Volume 4
      • June 28, 2014
      • Fritz H. Bach + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 9 2 1
      • eBook
        9 7 8 1 4 8 3 2 1 6 3 5 5
      Clinical Immunobiology, Volume 4 is a 13-chapter text that covers the advances in understanding of the concepts and practical applications of lymphoid subpopulations and the major histocompatibility complex (MHC). The first chapter presents an overview of the problems of various subpopulations of cells involved in the immune system. The succeeding chapters describe the techniques used for cell classification, either by their cell surface phenotype or by their responsiveness to a series of different stimuli. These chapters include surveys of the methods of detection of complement receptors and expression of these receptors on the surface of both normal and leukemic human lymphocytes. A discussion of the evidence that different T-lymphocyte populations differentially express receptor for IgG and IgM is also provided. Other chapters describe the relationship of MHC to serology of cell surface antigens and reactivity in the mixed leukocyte culture test. This work also explores the methods that employ the so-called "proliferative and cytotoxic responses". The remaining chapters look into the association between HLA antigens and a variety of different diseases. These chapters also discuss other genetic markers in the HLA linkage group. This book will be of great value to clinical immunobiologists, practicing physicians, researchers, and medical and biology students.

    • Enzyme Regulation and Mechanism of Action

      • 1st Edition
      • May 19, 2014
      • P. Mildner + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 3 3 2 0
      • eBook
        9 7 8 1 4 8 3 1 8 9 1 3 0
      Enzyme Regulation and Mechanism of Action contains the proceedings of the Federation of European Biochemical Societies' Special Meeting on Enzymes held in Dubrovnik, Croatia in 1979. The meeting provided a forum for reviewing advances in understanding the regulation and mechanism of action of enzymes. The discussions are organized around three themes: regulation of enzyme activity; the role of enzymes in the synthesis of nucleic acids and proteins; and proteolytic enzymes. Comprised of 33 chapters, this volume begins with an analysis of partial amino acid sequence of rabbit liver fructose 1,6-bisphophatase and sites of cleavage by proteinases. The reader is then introduced to physiological inactivation of enzymes in yeasts; structure and functions of protein kinases; and control points in the citric acid cycle. Subsequent chapters focus on ligand binding properties and subunit interactions in yeast alcohol dehydrogenase; the role of water in the acceleration of an enzymatic reaction; DNA polymerases of human normal and leukemic cells; and the phylogenetic and developmental aspects of gastric proteinases and their zymogens. This book is intended for enzymologists.

    • The Receptors

      • 1st Edition
      • May 10, 2014
      • P. Michael Conn
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 7 5 6 5
      • eBook
        9 7 8 1 4 8 3 2 7 3 1 3 6
      The Receptors, Volume III deals with receptors for interferons, hormones, and growth factors as well as for ?-aminobutyric acid, tuftsin, somatomedin, and insulin. Prolactin and nicotine receptors are also considered, along with the protein tyrosine kinase activity of hormone and growth factor receptors. Comprised of 12 chapters, this volume begins with a detailed account of secretory component (SC) as a receptor for polymeric immunoglobulins and the importance of SC-polymeric immunoglobulin A interactions in the mucosal immune system. The discussion then turns to interferon receptors and what is known about the fate of interferons and their receptors after binding; the use of muscimol in ligand-binding studies aimed at characterizing ?-aminobutyric acid receptors; and the role of protease nexins in the interaction of proteases with cells and in the regulation of proteolytic activity in the interstitial fluid immediately surrounding cells. Subsequent chapters focus on receptor regulation of phosphoinositides and calcium; effects of phospholipid turnover on receptor function; dynamics of tuftsin receptors; and the structure, function, and regulation of somatomedin receptors. The book also examines the internalization and intracellular processing of insulin receptors before concluding with an analysis of prolactin and nicotine receptors. This monograph will be a valuable resource for students and practitioners in fields ranging from cell biology and biochemistry to physiology, endocrinology, and pharmacology.

    • Commentaries in the Neurosciences

      • 1st Edition
      • April 24, 2014
      • A. D. Smith + 2 more
      • English
      • eBook
        9 7 8 1 4 8 3 1 4 8 7 3 1
      Commentaries in the Neurosciences is a compilation of the commentaries segment featured in the Neuroscience journal. This book, however, does not provide a comprehensive account of all fields in neuroscience, but rather articles that highlight developments during the past years. The topics covered include chemistry and dynamics of neurotransmitter storage particles; release of central and peripheral neurotransmitters; and transmitters in the enteric nervous system. This book also discusses the properties of neuroreceptors; chemistry and connections of the cerebral cortex; and intracellular recording and ionic transmembrane currents. This text explains as well the invertebrate nervous systems; functions of the nervous system including neuro- and psychopharmacology; and the mind-body problem. This book will be of use not only to research workers interested in keeping updated with developments in different areas of the neurosciences, but also to advanced undergraduate and graduate students who are studying the nervous system.

    • Biomedical Imaging

      • 1st Edition
      • January 27, 2014
      • Peter Morris
      • English
      • Hardback
        9 7 8 0 8 5 7 0 9 1 2 7 7
      • Paperback
        9 7 8 0 0 8 1 0 1 5 1 9 3
      • eBook
        9 7 8 0 8 5 7 0 9 7 4 7 7
      Biomedical Imaging: Applications and Advances discusses the technologies and latest developments in the increasingly important field of imaging techniques for the diagnosis of disease, monitoring of medical implants, and strategies for personalized medicine. Chapters in part one explore the full range of imaging technologies from atomic force microscopy (AFM) to positron emission tomography (PET), as well as the next-generation techniques that could provide the basis for personalized medicine. Part two highlights application-specific biomedical imaging methods, including ophthalmic imaging of ocular circulation, imaging methods for detection of joint degeneration, neural brain activation imaging, and the use of brain imaging to assess post-therapy responses. Further chapters review intravascular, cardiovascular, and whole-body magnetic resonance imaging (MRI). Biomedical Imaging is a technical resource for those concerned with imaging and diagnosis, including materials scientists and engineers as well as clinicians and academics.

    • Anaerobic Bacteriology

      • 3rd Edition
      • June 28, 2014
      • A. Trevor Willis
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 6 0 4 8
      • eBook
        9 7 8 1 4 8 3 1 9 1 8 5 0
      Anaerobic Bacteriology: Clinical and Laboratory Practice, Third edition discusses the importance of the non-sporing anaerobic bacteria as a significant cause of infection in man. This edition updates the anaerobic methodology, systematics, and ecological and pathogenetic associations of the non-sporing anaerobes. The descriptive bacteriology of the non-clostridial anaerobes and clinical syndromes produced by them in man are also considered. Other topics discussed include the anaerobic jar, inoculation of media, and antibiotic susceptibility testing of anaerobes. The histotoxic clostridia of infected wounds, anaerobic cocci, and infections related to the gastrointestinal tract are also elaborated. This text likewise covers the uterine gas gangrenous infections and other clostridial infections. This book is a good source for medical practitioners, clinicians, and medical students concerned with anaerobic bacteria.

    • Fertilization

      • 1st Edition
      • May 12, 2014
      • Charles B. Metz + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 1 0 1 1
      • eBook
        9 7 8 1 4 8 3 2 5 8 4 3 0
      Fertilization: Comparative Morphology, Biochemistry, and Immunology, Volume I focuses on the many aspects of the physiological mechanisms of fertilization in different forms of life. The selection first tackles the problems and procedures of comparative gametology and syngamy and sperm motility. Discussions focus on the morphology of cilia and flagella, extraneous chemical and physical factors, motility in male and female reproductive tests, problems of the quantitative and qualitative control of fertility, and patterns of reproduction. The text then ponders on sperm metabolism and mechanisms of gametic approach in plants. The manuscript takes a look at gamete surface components and their role in fertilization, acrosome reaction and lysins, and membrane fusion in relation to sperm-egg association. Topics include gametic association, acrosome formation during spermiogenesis, fine-structure studies of acrosomal changes, specificity of fertilization, and amphibian fertilization. The book also examines the activation of the egg and parthenogenesis in vertebrates. The selection is a valuable reference for readers interested in the processes involved in fertilization.

    • Heat Treatment for Insect Control

      • 1st Edition
      • September 5, 2014
      • Dave Hammond
      • English
      • Hardback
        9 7 8 0 8 5 7 0 9 7 7 6 7
      • Paperback
        9 7 8 0 0 8 1 0 1 5 1 2 4
      • eBook
        9 7 8 0 8 5 7 0 9 7 8 1 1
      Stored product insects and other pests represent a major hygiene and safety issue to many industries, from food production to building infestation, and issues for timber pallets and packaging. Beds bugs are rapidly becoming a public health issue in hotels, hostels and houses in many parts of the world. While fumigation has been one of the prevalent routes for pest control, there remain issues with the toxicity of the chemicals used and potential exposure to humans therefore heat treatment has proven to be a successful alternative when used correctly. It is well known that excessive heat is dangerous to life. There is a difference between the amount of heat required to kill microbes such as bacteria and viruses and that required to kill larger life forms such as insects or mammals. This book focuses on the use of heat to kill insects and mites in food production, storage and other facilities. Heat Treatment for Insect Control examines how controlled heat treatment kills all stages of pest insect life across species and without causing damage to surrounding structures or electronics. The advantages of heat treatment include no health & safety hazards, a completely controllable and environmentally friendly process, reduced treatment time of fumigation (hours verses days), as well as no factory shutdown or exclusion of staff from adjacent areas during treatment. Part I reviews the principles of heat treatment, with chapters covering the fundamentals, planning, best practice and costs of integrated pest management. Part II looks at heat treatment applications in food production, storage, food materials and fresh produce. Part III examines the other applications in clothing, small rooms, buildings, and transportation.

    • Urea as a Protein Supplement

      • 1st Edition
      • May 16, 2014
      • Michael H. Briggs
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 9 4 1 0
      • eBook
        9 7 8 1 4 8 3 1 5 1 8 3 0
      Urea as a Protein Supplement presents the significant advances that have been made in ruminant nutrition. This book examines the role of the rumen flora and fauna as synthesizers of protein from non-protein nitrogen sources such as ammonium compounds and urea. Organized into four parts encompassing 23 chapters, this book starts with an overview of the use of urea and other non-protein nitrogen sources in ruminant nutrition. This text then explores the various methods that may be used for the preparation of urea, which involves the dehydration of ammonium carbamate produced by the reaction of carbon dioxide and ammonia at high pressure and temperature. Other chapters consider the ways in which urea could be utilized to increase protein supplies. The final chapter deals with the hydrolysis of urea by urease to ammonia and carbon dioxide, which has been used as a method for determining urea for many years. Agricultural scientists and farmers will find this book useful.

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