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Books in Life sciences

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  • Immunological Methods

    Volume IV
    • 1st Edition
    • Ivan Lefkovits + 1 more
    • English
    Immunological Methods, Volume IV provides information pertinent to the methods in immunological research. This book focuses on cells, clones, and cell lines, as well as on their components and secreted products. Organized into 21 chapters, this volume begins with an overview of hybridoma methodology as the most celebrated immunological method. This text then discusses cell fusion, hybridoma technology, and everything related to monoclonal antibodies. Other chapters consider another molecular biology method, which describes the procedure required for establishing a partitioned cDNA-library. This book provides as well a comprehensive analysis of mRNA populations in which every messenger species appears as a distinct element, and so provides accurate answers to questions concerning genetic complexity. The final chapter provides an example of how transgenic mice can be used to study the development of T cell repertoires. This book is a valuable resource for cell biologists, scientists, immunologists, and research workers.

  • Calcium Physiology

    An Advanced Treatise
    • 1st Edition
    • C. L. Comar + 1 more
    • English
    Mineral Metabolism, Volume III: Calcium Physiology focuses on the processes, reactions, and approaches involved in calcium metabolism and study of bones. The selection first underscores the measurements and models of skeletal metabolism and advances in the physical biology of bone and other hard tissues, including measurements and concepts, composition and structure of bone minerals, and dynamic studies of bone minerals. The text then takes a look at calcium and striated muscle and renal excretion of alkaline earths. Topics include physicochemical state of alkaline earth cations in plasma and urine, effects of drugs, renal diseases, calcium and contractile proteins, resting potential and action potential, calcium and muscle contraction, and coupling of excitation and energy synthesis. The book examines the aspects of intestinal absorption of calcium, with special reference to vitamin D, as well as the physiological mechanism of the intestinal absorption of calcium; effect of other nutritional and physiological factors on calcium absorption; and structure of the intestinal epithelial cell. The selection is a dependable source material for physiologists and readers interested to pursue research on calcium physiology.

  • Evolving Genes and Proteins

    A Symposium Held at the Institute of Microbiology of Rutgers • the State University with Support from the National Science Foundation
    • 1st Edition
    • Vernon Bryson + 1 more
    • English
    Evolving Genes and Proteins covers the proceedings of the "Evolving Genes and Proteins" symposium, held at the Institute of Microbiology of Rutgers, The State University on September 17 and 18, 1964, with support from the National Science Foundation. The book focuses on the structural and functional features of proteins and nucleic acids. The selection first offers information on lysine biosynthesis and evolution, lipid patterns in the evolution of organisms, and evolution of heme and chlorophyll. Discussions focus on the evolution of the genes of the porphyrin biosynthetic chain, polyunsaturated fatty acids in plants and animals, and diagnostic radiocarbon tracers. The text then examines evolutionary divergence and convergence in proteins; evolution of hemoglobin in primates; and constancy and variability of protein structure in respiratory and viral proteins. The publication takes a look at the comparative aspects of the structure and function of phosphoglucomutase, evolution of dehydrogenases, and enzymatic homology and analogy in phylogeny. The text also ponders on the evolution of an enzyme, role of mutations in evolution, enzyme catalysis and color of light in bioluminescent reactions, and evolution of the lactose utilization gene system in enteric bacteria. The selection is a valuable reference for microbiologists and readers interested in the study of genes and proteins.

  • Oxygenases

    • 1st Edition
    • Osamu Hayaishi
    • English
    Oxygenases focuses on the processes, methodologies, technologies, and approaches involved in oxygenases, including its distribution in animals, plants, and microorganisms and its role in the metabolism of aromatic, cyclic, and aliphatic compounds. The selection first offers information on the history and scope of oxygenases, methodology of oxygen isotopes, and phenolytic oxygenases. Discussions focus on the separation and purification of compounds for isotopic analysis; general properties and mechanisms of action of oxygenases; physiological significance of oxygenases; dehydrogenases, oxidases, and oxygenases; and problems and restrictions in the use of oxygen-18. The text then examines aromatic hydroxylations, oxygenases in lipid and steroid metabolism, and bacterial oxidation of hydrocarbons. Topics include anaerobic oxidation of alkanes, involvement of molecular oxygen in hydrocarbon utilization, steroid hydroxylation mechanisms, oxygenases in the biosynthesis of steroid hormones, conversion of dopamine to norepinephrine, and general discussion of mechanism of aerobic hydroxylation reactions. The selection is a valuable reference for researchers interested in the process of oxygenases.

  • Malaria

    Immunology and Immunization
    • 1st Edition
    • Julius P. Kreier
    • English
    Malaria: Volume 3, Immunology and Immunization is a collection of papers dealing with malaria parasites, the methods for measuring the immunological response to plasmodia, and the vertebrates host's immune response to plasmodia. Some papers discuss immunization against sporozoites, against the exoerythrocytic stages of malaria parasites, against asexual blood-inhabiting stages of plasmodia, as well as gamete immunization in malaria. One paper describes various separation methods to isolate malaria parasites and their constituents. Another paper discusses in detail the theory and practice of methods used in measuring antibody responses which occur during plasmodial infections, including the antibody response against sporozoites, exoerythrocytic forms, and in the different blood stages. Another paper explains the vertebrate host's immune response to plasmodial infection as a homeostatic physiological response changing along with the progression of the disease. The changes in the dynamic cellular cascade are different as the disease progresses causing death, than when these lead to recovery. Another paper enumerates the parameters which determine malarial infectiousness from one individual to another such as the time of onset, duration, intensity of the blood infections, as well as the maturity, longevity, and rate of production of gametocytes. Pharmacologists, general medical practitioners, investigators, and laboratory technicians involved in malarial research will find the collection very useful.

  • MCQ Tutor for Students of Microbiology

    • 1st Edition
    • John Gordon
    • English
    MCQ Tutor for Students of Microbiology provides a series of multiple choice questions with annotated answers, mainly in bacteriology but also including parasitology, virology, and immunology. This book focuses on clinical applications. Organized into four parts, this book begins with an overview of the pre-clinical aspects of microbiology and host defense mechanisms. This text then deals with microbial systematics as well as the detailed properties of the various microorganisms. Other parts cover the nature and manifestation of a wide spectrum of infective diseases. This book discusses as well the laboratory diagnosis, treatment, and prevention of infective diseases. The final part deals with other examples of other forms of multiple choice question. This book is intended to be suitable for medical students in the second and third undergraduate years as an aid to preparation for their third MB examination. Students of medical and laboratory sciences as well as candidates for diploma and college examinations will also find this book useful.

  • Polysaccharides Peptides and Proteins

    Pharmaceutical Monographs
    • 1st Edition
    • R. T. Coutts + 1 more
    • J. B. Stenlake
    • English
    Pharmaceutical Monographs, Volume 4: Polysaccharides Peptides and Proteins provides information pertinent to a wide variety of naturally-occurring macromolecules that are either peptide, protein, or polysaccharide in nature, which are important as medicinal and pharmaceutical agents. This monograph presents the basic physical and chemical properties of polysaccharides. Organized into four chapters, this volume begins with an overview of the pharmaceutical importance of the class of compounds known as polysaccharides. This text then provides data on the structure of the polysaccharides that is obtained by isolating and identifying the product formed on hydrolysis of the molecule itself. Other chapters consider plant gums and mucilages as important medicinal and pharmaceutical products. This monograph discusses as well the autohydrolysis of gum arabic. The final chapter deals with the clinical applications of various peptide-type antibiotics. This monograph is a valuable resource for undergraduate students of pharmacy and allied subjects.

  • A Text - Book of Bacteriology

    • 4th Edition
    • R. W. Fairbrother
    • English
    A Textbook of Bacteriology, Fourth Edition provides information pertinent to the medical aspects of bacteriology. This book presents the importance of sulfonamide compounds in the treatment of many bacterial diseases. Organized into three parts encompassing 38 chapters, this edition begins with an overview of the salient features of the development of bacteriology. This text then explores the food requirements of the bacteria as well as the elements necessary for the synthesis of the bacterial protoplasm. Other chapters consider the numerous and complex factors involved in the reproduction of bacteria. This book discusses as well the presence of antitoxins in the serum of an individual, which is an indication of increased resistance to infection with the homologous organism. The final chapter deals with serological reactions that are most widely used, namely, agglutination, precipitation, and complement-fixation. This book is a valuable resource for medical students, physicists, bacteriologists, chemists, biochemists, and research workers.

  • Essentials of ABO -Rh Grouping and Compatibility Testing

    Theoretical Aspects and Practical Application
    • 1st Edition
    • W. John Lockyer
    • English
    Essentials of ABO-Rh Grouping and Compatibility Testing: Theoretical Aspects and Practical Application focuses on overall safety in blood transfusion, including accurate ABO and Rh-D grouping of both patient and donor. The book first elaborates on the ABO blood group system and the Rh blood group system and hemolytic disease of the newborn. Discussions focus on the Rh-D antigen, Rh genotyping, Rh testing of blood donors and recipients of blood, antenatal and postnatal serology in cases other than Rh and ABO hemolytic disease, selection and preparation of Rh anti-D grouping reagent, dangerous group O donor blood, alternative sources of anti-A and anti-B blood grouping reagent, and development of the A and B red cell antigens. The manuscript then takes a look at compatibility testing (crossmatching) and transfusion reaction investigations, as well as compatibility testing and preparation of blood for patients with antibodies to serum proteins; compatibility testing of patients with known irregular antibodies; non-urgent compatibility testing of blood; and compatibility testing for patients requiring platelets. The publication takes a look at practical procedures, including grades of agglutination, control of anti-human globulin serum, preparation of low ionic strength saline, and preparation of platelet concentrates. The text is a valuable source of information for researchers interested in ABO-Rh grouping and compatibility testing.

  • An Introduction to Biochemistry

    • 2nd Edition
    • William Robert Fearon
    • English
    An Introduction to Biochemistry, Second Edition provides information pertinent to the fundamental aspects of biochemistry. This book presents several analytical methods, including the citrulline reaction for proteins and the diffusion test for acetone. Organized into two parts encompassing 25 chapters, this edition begins with an overview of the general composition of the organism and the chemical characteristics of the chief organic and inorganic compounds that enter into its structure. This text then examines the chemical composition of the tissues and physiological systems. Other chapters consider the occurrence and identification of several pathological constituents of urine, which presents features of biochemical interest. This book discusses as well the significance and analytical reactions of the bile acids and esters. The final chapter deals with the internal environment, which in the higher animal is represented by the blood and the cerebrospinal and other tissue fluids. This book is a valuable resource for biochemists.

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