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Books in Life sciences

  • Methods in Virology

    Volume V
    • 1st Edition
    • June 28, 2014
    • Karl Maramorosch + 1 more
    • English
    Methods in Virology, Volume V focuses on the methods used in virology, including hybridization, gel electrophoresis, freeze-etching technique, and ultracentrifugation. The selection first offers information on the fusion of cells for virus studies and production of cell hybrids; approaches to ultracentrifugation; and polyacrylamide gel electrophoresis of viral RNA. Discussions focus on applications to virological problems and analysis of results; analysis of the distribution of RNA on polyacrylamide gels after electrophoresis; and biological analysis of DNA components. The book then examines the polyacrylamide gel electrophoresis of viral proteins, DNA-RNA and DNA-DNA hybridization in virus research, and techniques of RNA-DNA hybridization in solution for the study of viral transcription. Topics include preparation of nucleic acids, hybridization and elution procedures that minimize RNA degradation, and procedures for acrylamide gel electrophoresis. The text takes a look at freeze-etching technique for the study of virus ultrastructure; procedures to increase virus yield from infected plants; and the immunoperoxidase technique. Concerns include principles of the immunoperoxidase technique, histochemical detection of peroxidase activity, sequence of events in virus infection, and factors affecting virus yield. The selection is a valuable source of data for researchers interested in the methods employed in virology.

  • Immunointervention in Autoimmune Diseases

    Papers Based on an International Meeting in Paris, France, in June 1988
    • 1st Edition
    • June 28, 2014
    • J. F. Bach
    • English
    Immunointervention in Autoimmune Diseases is a collection of papers presented at the 1988 International Meeting by the same title, held in Paris, France. This text contains 21 chapters and begins with surveys of the role of antigen in autoimmune responses and the moving boundaries between physiology and pathology of immunity. The succeeding chapters deal with the regulation, immunosuppressive therapy, infections, and immunointervention of autoimmune disorders. These topics are followed by discussions of specific immunosuppressive therapy for a particular disease, including type I diabetes, T-cell leukemia, and systemic lupus erythomatosus. This work also explores the principles of allograft, the use of monoclonal antibody, and OKT3. The remaining chapters consider the maintenance of autoimmunity and the risk/benefit in immunointervention for autoimmune diseases. This book will prove useful to immunologists, pathologists, physiologists, and researchers.

  • Handbook of Immunological Investigations in Children

    Handbooks of Investigation in Children
    • 1st Edition
    • June 28, 2014
    • J. Graham Watson + 1 more
    • English
    Handbook of Immunological Investigations in Children presents an extensive examination of the immune system of children. It discusses the fundamental concepts in immunology. It addresses studies in the primary immunodeficiency diseases. Some of the topics covered in the book are the respiratory disorders; renal disorders; gastrointestinal disorders; endocrine disorders; neurological and psychiatric disease; identifications of diseases of the skin; muscle malfunction and connective tissue disorder; and the methods of infections and immunizations. The definition and description of factors influencing blood and blood-forming elements are fully covered. An in-depth account of the factors causing allergies and cardiovascular diseases are provided. The general characteristics of severe combined immunodeficiency are completely presented. A chapter is devoted to usage of immunoglobulin therapy. Another section focuses on the disorders of neutrophils, monocytes, and macrophages. The book can provide useful information to immunologists, pediatricians, doctors, students, and researchers.

  • Carbohydrates

    • 1st Edition
    • Volume 5
    • June 28, 2014
    • Marcel Florkin + 1 more
    • English
    Comprehensive Biochemisty, Volume 5: Carbohydrates deals with the organic and physical chemistry of the major organic constituents of living material. This book discusses the general structure of monosaccharides, detection and estimation of aldonic acids, intramolecular rearrangement of N-glycosides, and preparation of sugar phosphates. The deacetylation of glycoside acetates, naturally occurring oligosaccharides of human milk, and molecular weight of polysaccharides are also elaborated. This text likewise covers the biogenesis and fate of pectic substances in plant tissues, complex polysaccharides of gram-positive bacteria, galactosaminoglycan of Aspergillus parasiticus, and chemical structure of heparin sulfate. This volume is a good source for biochemists and researchers conducting work on carbohydrates.

  • Photochemistry

    An Introduction
    • 1st Edition
    • June 28, 2014
    • D. R. Arnold + 2 more
    • English
    Photochemistry: An Introduction covers topics such as industrial photochemistry, solid state photochemistry, spectroscopy and photochemistry of the solid state, industrial applications of photochemistry, and photochromism. The book discusses the application of bonding, structure, energetics, and reactivity of the ground states of molecules to describe the same properties for molecules in their electronically excited states; the electronic spectra of excited states; and how the excited states react to form chemical transients. The text also describes light sources, techniques for measuring light intensities and quantum yields, methods used to detect transient photochemical products, and some ancilliary techniques. A review of some features of typical photochemical processes conducted in the vapor state and a survey of the reactions of the urban atmosphere, are also considered. The book further tackles the mechanisms of organic photochemical reactions; the synthetic applications of organic photochemistry; and the photochemistry of the solid state. The text also looks into photochromism and the industrial applications of photochemistry. People involved in the field of photochemistry will find the book useful.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 17
    • June 28, 2014
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 17 is a six-chapter text that covers the most prevalent problems in lipoprotein mechanism research works. The opening chapters examine the metabolic role of high-density lipoproteins (HDL), specifically the role of HDL in cholesterol transport. The next chapter discusses cholesterol metabolism in various types of clinical hyperlipidemias and describes cholesterol turnover as a function of hypercholesterolemia... hypertriglyceridemia... or a combination of the two. Other chapters deal with the hypocholesterolemic effect of polyunsaturated fats on man, as well as the mechanism of lipid peroxidation in mitochondrial membranes and its effects on alterations in cellular processes. The closing chapter relates to membrane phenomena, with particular emphasis to the study of membrane structure by means of membrane-cooperative enzymes. This chapter also explores the application of allosterism as a tool for membrane research. This book will prove useful to lipid and enzyme chemists, biochemists, and researchers.

  • The Third World Congress on Biosensors Abstracts

    1-3 June 1994, New Orleans, USA
    • 1st Edition
    • June 28, 2014
    • Abstracts
    • English
    Biosensors 94: The Third World Congress on Biosensors Abstracts focuses on the progress in the field of biosensors, including immuno-absorbent 'catch' system, surface plasmon resonance, and chemiluminescence. The selection first offers information on the development of a commercial multichannel clinical sensor chip; commercial development and application of biosensors; amperometric biosensors based on dehydrogenase/NAD and heterocyclic quinones; and enzyme-epoxy membrane based semi-automated glucose analyzing system. The text then takes a look at the orientation of antibody fragments to increase TIRF immunosensor efficiency and the development of latex-technology for specific DNA detection with surface plasmon resonance. The book elaborates on gas-phase biosensor for the determination of ethanol vapor; novel electrochemical gas phase biosensors for the detection of phenolic vapors; and the development of an immuno-absorbent 'catch' system for the detection of pesticides and pesticide analogues. The book also ponders on the kinetics of binding of immobilized antibodies under nonequilibrium, flow conditions; flow injection thin-layer cell immunosensor with chemiluminescent detection of peroxidase label; and new optical fiber sensor for detecting chemiluminescence and its application to immunoassay. The selection is a valuable source of data for researchers interested in biosensors.

  • Immunological Tolerance

    Mechanisms and Potential Therapeutic Applications
    • 1st Edition
    • June 28, 2014
    • David H. Katz + 1 more
    • English
    Immunological Tolerance: Mechanisms and Potential Therapeutic Applications documents the proceedings of a conference held at Brook Lodge, Michigan, April 27-May 1, 1974. The conference brought together many of the investigators who have actively contributed to furthering knowledge and understanding of immunological tolerance. It will be immediately clear to the reader that the conference was structured in a way to consider phenomena of tolerance and immune suppression as interrelated entities with a certain degree of emphasis on the possible common cellular mechanisms involved. The volume contains 36 contributions presented during the seven sessions of the conference. The papers presented in Session I examined T-cell tolerance. The presentations in Session II focused on B cell tolerance. The papers in Sessions III and IV focused on the mechanisms of B cell and T cell tolerance, respectively. Session V dealt with the activity of suppressor cells as a mechanism of tolerance. The papers in Session VI investigated the suppressive activity of antibody and antigen-antibody complexes. In Session VII a final General Discussion was held in order to identify what has been established concerning the phenomenology and mechanisms of specific immunological tolerance, what are the major unresolved issues, and what approaches appear most promising to answer these questions.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 23
    • June 28, 2014
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 23 provides information pertinent to mammalian as well as plant metabolism. This book presents important data on apoproteins, which may offer a foothold for further probes of the genetics underlying increased susceptibility to ischemic heart disease. Organized into seven chapters, this volume begins with an overview of the molecular biology of human apolipoproteins B and E. This text then explains the lipid metabolism of dermatophytes and describes their lipid composition and how it may be modulated. Other chapters consider the function, distribution, and biosynthesis of the sterols of fungi and examine the influences of fungal sterols on membrane fluidity. This book discusses as well the biosynthesis and degradation of platelet-activating factor (PAF) as well as its physiological function. The final chapter deals with one specific area of PAF activity, namely, renal processes. This book is a valuable resource for biologist, biochemists, chemists, and clinicians.

  • Current Topics in Bioenergetics

    Structure, Biogenesis, and Assembly of Energy Transducing Enzyme Systems
    • 1st Edition
    • June 28, 2014
    • C. P. Lee
    • English
    Current Topics in Bioenergetics, Volume 15: Structure, Biogenesis, and Assembly of Energy Transducing Enzyme Systems presents the reaction mechanisms involved in membrane-associated energy transducing processes at the molecular level. This book discusses the developments in the energy transducing systems. Organized into 11 chapters, this volume begins with an overview of the composition and structural aspects of the four respiratory chain complexes. This text then discusses the genetic aspects of various energy transducing systems. Other chapters consider the electron transfer chains of chloroplast, mitochondria, and some photosynthetic bacteria, which contain a multiprotein complex with similar functional and structural properties. This book discusses as well the structure and function of multiple and variable amounts of subunits in cytochrome-c oxidase from various organisms. The final chapter deals with the interdisciplinary path of bioenergetics, with the center of gravity moving from chemistry through genetics to physics. This book is a valuable resource for biologists.

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