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Books in Life sciences

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  • Regulation of Secondary Product and Plant Hormone Metabolism

    FEBS Federation of European Biochemical Societies: 12th Meeting, Dresden, 1978
    • 1st Edition
    • M. Luckner + 1 more
    • English
    Regulation of Secondary Product and Plant Hormone Metabolism contains the proceedings of the 12th Meeting of the Federation of European Biochemical Societies held in Dresden, Germany in 1978. The meeting provided a forum for discussing progress in understanding the regulation of the metabolism of secondary products and plant hormones. It shows that the processes regulating secondary metabolism are similar in lower and higher plants, and that the molecular basis of cell differentiation and specialization is uniform in all groups of living organisms. Comprised of 22 chapters, this volume begins with an overview of the interrelationships between secondary products and hormones in plants, followed by a detailed account of the effects of phenolic compounds on auxin biosynthesis and vice versa. The reader is then introduced to non-ribosomal biosynthesis of biologically active peptides; channelling of intermediates during the biosynthesis of cyanogenic glycosides; and intracellular distribution of flavonoids in glandular cells. Subsequent chapters explore the regulation of gene expression in secondary biosynthesis; inhibition of phenylalanine ammonia-lyase by cinnamic acid derivatives; novel inhibitors of phenylpropanoid metabolism in higher plants; and stage-specific phenylpropanoid metabolism during pollen development. This book will be of interest to biochemists and geneticists.

  • Protides of the Biological Fluids

    Proceedings of the Twenty-Third Colloquium, Brugge, 1975
    • 1st Edition
    • H. Peeters
    • English
    Protides of the Biological Fluids contains the proceedings of the 23rd Colloquium on "Protides of the Biological Fluids" held in Brugge, Belgium in 1975. The discussions were organized around three themes: proteinase inhibitors, clinical evaluation of plasma protein patterns, and affinity chromatography. Comprised of 117 chapters, this volume begins with an overview of carcinofetal proteins, followed by an analysis of proteinase inhibition. The reader is then introduced to the mechanism and structure of human alpha-1-proteinase inhibitor; some properties of a complex between ?2-macroglobulin and brinase; and the interaction of proteinase inhibitors with blastocyst proteinases involved in implantation. Subsequent chapters deal with the thermodynamics and kinetics of the interaction of trypsin with trypsin inhibitors; purification and characterization of acid-stable proteinase inhibitors from human seminal plasma; and the possible role of protease inhibitors in cartilage metabolism. The book also explores the structure and function of animal proteinase inhibitors as well as techniques and methods used in clinical evaluation of plasma protein patterns. This monograph will be of interest to biologists and research workers in biology.

  • Extraretinal Photoreception

    Proceedings of the Symposium and Extraretinal Photoreception in Circadian Rhythms and Related Phenomena
    • 1st Edition
    • Michael Menaker
    • English

  • Reflections on Biochemistry

    In Honour of Severo Ochoa
    • 1st Edition
    • A. Kornberg + 2 more
    • English
    Reflections on Biochemistry: In Honour of Severo Ochoa offers reflections on a wide range of topics relating to biochemistry, including energy metabolism, lipids and saccharides, regulation, nucleic acids and the genetic code, protein biosynthesis, and cell biology. The essays celebrate Severo Ochoa's outstanding contributions to biochemistry spanning nearly half a century. This book is comprised of 47 chapters and begins with a biography of Ochoa and his scientific work in the field of biochemistry, particularly his research on intermediary metabolism, RNA synthesis, and the genetic code. The discussion then turns to energy metabolism, photosynthesis, and fermentation, touching on topics such as the role of lactic acid in the development of biochemistry and the biosynthesis of cell components from acetate. The next section is devoted to lipids, saccharides, and cell walls and includes chapters that deal with biotin, sulfur biochemistry, and dipicolinic acid. Subsequent chapters explore hormonal regulation of adipose tissue lipolysis; the structural relationship between genes and enzymes; bacteriophages, colicins, and ribosomes; and cell biology and neurobiology. This monograph will be of interest to biochemists and students of biochemistry.

  • Regulatory Proteolytic Enzymes and Their Inhibitors

    11th Meeting Copenhagen 1977
    • 1st Edition
    • Staffan Magnusson + 2 more
    • English
    Regulatory Proteolytic Enzymes and Their Inhibitors consists of contributed papers from the 11th Meeting of the Federation of European Biochemical Societies in Copenhagen in 1977. This collection describes the role of proteases in the physiological regulation, a matter of the activation and de-activation of enzymes. The text also discusses the activation mechanism of pepsinogen and other acid protease zymogens. One paper reviews a discovery — that of a separate and distinct class of precursors, the pre-secretary proteins, and then discusses other studies on preproinsulin. The text then discusses the primary structures and presumed functions of immunoglobulin precursors. Another paper continues with the work of Reich and co-workers who found that transformation of cultured fibroblasts from different species by oncogenic viruses is related to the production and release of proteases that are responsible in activating the proenzyme plasminogen into plasmin. Another paper discusses plasminogen activation as having some relationship with pathological processes. The book also reviews the plasminogen activator secretion by normal and neoplastic human tissues. The text discusses the results when primary cultures established from biopsies of normal kidneys secreted plasminogen activators in amounts over those secreted by actual malignant tissues. The book then notes the role of neutral and acid proteinases in male reproduction and the role of plasminogen activators in female ovulation. This collection can be useful for micro-biologists, research biologists, molecular scientists, and students of molecular biology.

  • Progress in Biophysics and Molecular Biology

    • 1st Edition
    • J. A. V. Butler + 1 more
    • English
    Progress in Biophysics and Molecular Biology, Volume 32 summarizes the significant progress that has been made in the fields of biophysics and molecular biology. Topics range from metabolic regulation and transfer RNA to cellular metabolism and prokaryotic and eukaryotic ribosomes. This volume consists of five chapters and begins with a discussion of mathematical models used in the study of metabolic regulation, with emphasis on the energy metabolism of eukaryotes. The next chapter examines the possible functions of transfer RNA minor components, paying particular attention to the principle of location-function relationships. The reader is also introduced to spatial-functional correlations in cellular metabolism and highlights the role of organize multienzyme systems, along with the fundamentals of ribosome structure and function in prokaryotes and eukaryotes. A chapter that analyzes the structures and functions of transfer RNA concludes the book. This book will be of interest to scientists, students, and researchers working in the fields of biophysics and molecular biology.

  • Protides of the Biological Fluids

    Proceedings of the Twenty-Fourth Colloquium, Brugge, 1976
    • 1st Edition
    • H. Peeters
    • English
    Protides of the Biological Fluids contains the proceedings of the XXIVth Colloquium on Protides of the Biological Fluids held in Brugge, Belgium in 1976. Contributors explore relevant findings about protides of biological fluids and discuss topics such as pregnancy-associated proteins, carcino-fetal and carcinoplacental proteins, and molecular amplification. This volume consists of 151 chapters organized into three sections and begins with a discussion of the problems of specific placental and fetal proteins as well as the appearance of these proteins in maternal serum. The biochemistry and structure of human placental lactogen is considered together with its possible application in the diagnosis of abnormal pregnancy and the role of pregnancy specific proteins especially with regard to immunization during pregnancy. The next section focuses on oncofetal proteins, with particular reference to the biological significance of alpha-fetoprotein, its appearance during various types of cancer, and its increase in abnormal pregnancy. The isolation and properties of CEA and related antigens such as TPA, and the importance of their assay in early cancer detection as well as in follow-up studies of patients after surgery or therapy are described. The final section explores the use of molecular amplification in detection of trace amounts of proteins. It explains how radio-immunoassay, RIA, or ELISA can amplify a basic reaction between two molecules and increase its specificity as well as its limits of detection. This book will be of interest to scientists, students, and researchers working in the fields of biology and biochemistry.

  • Cyclic Nucleotides and Protein Phosphorylation in Cell Regulation

    FEBS Federation of European Biochemical Societies: 12th Meeting, Dresden, 1978
    • 1st Edition
    • E.-G. Krause + 2 more
    • English
    Volume 54, Symposium S7: Cyclic Nucleotides and Protein Phosphorylation in Cell Regulation documents the proceedings of the 12th Federation of European Biochemical Societies (FEBS) Meeting held in Dresden, Germany on July 5-7, 1978. This book discusses the biological significance and biochemical aspects of cyclic nucleotides and protein phosphorylation in cell regulation. The general aspects of cyclic nucleotide metabolism and action; cyclic nucleotides and nervous system; and cyclic nucleotides in muscle tissues are also elaborated. This publication likewise covers the cyclic nucleotides in secretion processes and miscellaneous aspects of cyclic nucleotide-dependent and independent protein phosphorylation. This volume is valuable to biochemists and biologists concerned with the cyclic nucleotides and protein phosphorylation in cell regulation.

  • Albumin: Structure, Function and Uses

    • 1st Edition
    • Victor M. Rosenoer + 2 more
    • English
    Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed. This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism. This monograph should be a useful resource for biochemists and clinicians.

  • Gene Expression

    Protein Synthesis and Control RNA Synthesis and Control Chromatin Structure and Function
    • 1st Edition
    • Brian F. C. Clark + 2 more
    • English
    Gene Expression provides research papers on selected topics in gene expression, presented at the 11th meeting of the Federation of European Biochemical Societies, held at Copenhagen in August 1977. The book presents research knowledge provided by eminent researchers in the field of biochemistry. Each chapter contains material that is important to other researchers, such as on initiation mechanism of protein synthesis in prokaryotes; translocation mechanism of the ribosome; and analysis of ribosomal translocation by drugs. Mechanisms for the intracellular compartmentation of newly synthesized proteins; RNA synthesis and control; the sub-structure of nucleosome core particles; and future prospects on chromosome structure and function are detailed as well. The text will be of use to researchers and workers in the field of medicine, pharmacology, gene therapy, and biochemistry.

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