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Books in Life sciences

    • A Comprehensive Guide to Rodent Models of Liver Diseases

      • 1st Edition
      • March 15, 2025
      • Savneet Kaur + 1 more
      • English
      A Comprehensive Guide to Rodent Models of Liver Diseases provides the why, what, and how of preclinical models of liver disease. These models have not only substantially improved understanding of human liver disease pathogenesis, but also helped in developing and testing newer therapeutics as well as addressed some of the unanswered medical challenges and problems of today.This important reference gives a detailed and in-depth review of the various animal models of human liver disorders. Well-reported animal models several human liver diseases such as fatty liver disease (non-alcoholic and alcoholic) to steatohepatitis, cholestasis, fibrosis, cirrhosis and its complications are described. Preclinical models used for studying liver regeneration and liver failure are also discussed. For each model, the characteristic features, brief protocols, relevance, and limitations are provided.Preclinical models used for studying liver regeneration and liver failure are also discussed. For each model, the characteristic features, updated protocols, relevance, and limitations are provided for consideration. Finally, it provides an overview of the recently developed organoid models of liver pathology.
    • Role of Sex and Gender in Aging and Longevity

      • 1st Edition
      • July 14, 2025
      • Calogero Caruso
      • English
      • Paperback
        9 7 8 0 4 4 3 2 7 3 9 8 8
      • eBook
        9 7 8 0 4 4 3 2 7 3 9 9 5
      Role of Sex and Gender in Aging and Longevity aims to shed light on the complex interplay between sex and gender differences in the aging process and longevity of individuals. While biological sex differences have long been recognized as influencing various aspects of aging, this book includes how gender also plays a significant role in shaping these processes, accelerating aging, or favoring longevity. By acknowledging the influence of both biological and socially constructed factors, this book offers a comprehensive understanding of why individuals may experience different aging trajectories and have divergent longevity outcomes. This book explores the intricate ways in which gender norms, roles, and expectations shape individual experiences of aging and delves into the social determinants of health that can interact with biological factors to influence the aging process and longevity outcomes. By examining these interactions, this book aims to provide a nuanced understanding of the multifaceted nature of aging and longevity and how sex and gender contribute to these complex phenomena, laying the groundwork for future aging research and providing significant implications for disease prevention, screening, diagnosis, and treatment of age-related conditions.
    • Immunotherapy: Magic Bullet to Change the Future Therapeutics

      • 1st Edition
      • Volume 144
      • February 24, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 1 5 9 4 6 6
      • eBook
        9 7 8 0 4 4 3 1 5 9 4 7 3
      FORMTEXT Immunotherapy is emerging as a novel and reliable therapeutic technique for treating diseases such as autoimmunity, HIV/AIDS, allergy and cancers. Immunotherapy change or modulate our immune system functionalization and activate it to kill pathogen infected cells or affected cells. Development in the field of Immunology, Molecular Biology, and Pharmaceutical Sciences empower the immune system for protecting us agaist number of pathogenic infections. This volume consisit of the chapters from the different stalwarts of the field coveriing the topic such as Immunotherapy past and present, Oncolytic virus based therapy, CAR-T cell therapy, antibody engineering, adjuvant engineering etc. Chapters covered in this volume discuss the immunological translational research in the field of human cancer, parasitic and infectiouds diseases. This volume incudes the chapter describing the tools developed by scientist to engineers safe and effective antibody which can be used as powerful medicine durig human disease conditions. This volume will reflect the secret of biological sciences and technology in the field on immunology to develop safe and efficacious immune molecules based magic bullet to provide absolute cure. This volume will be helpful to the early career researchers and students working in the field of basic and applied immunological sciences.
    • Pharmacological Approaches in Cancer Treatment

      • 1st Edition
      • June 1, 2025
      • Sadhna Aggarwal
      • English
      • Paperback
        9 7 8 0 4 4 3 3 8 3 0 7 6
      • eBook
        9 7 8 0 4 4 3 3 8 3 0 8 3
      Pharmacological Approaches in Cancer Treatment: A Comprehensive Guide presents an in-depth exploration of pharmacological approaches utilized in cancer treatment. The book's overarching theme revolves around understanding the intricate mechanisms and applications of various therapies, ranging from targeted treatments to immunotherapies. Through examination and analysis, the content sheds light on emerging trends and breakthroughs in the field, providing a comprehensive overview of cancer pharmacology. Sections target therapies, chemotherapy agents, immunotherapy, personalized medicine, combination therapies, drug resistance, novel drug delivery systems, palliative care in oncology, adverse effects of cancer pharmacotherapy, and preclinical studies.Each chapter provides the nuances of its respective subject matter, providing readers with a thorough understanding of the scientific underpinnings and practical applications of cancer pharmacology. Designed to cater to both oncology professionals and patients, this book serves as a valuable resource for enhancing understanding and informing treatment decisions.
    • Lignin-Degrading Enzymes

      • 1st Edition
      • Volume 716
      • June 18, 2025
      • English
      • Hardback
        9 7 8 0 4 4 3 3 4 3 0 4 9
      • eBook
        9 7 8 0 4 4 3 3 4 3 0 5 6
      Lignin-Degrading Enzymes volume 716 highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
    • Bioinformatics Essentials

      • 1st Edition
      • June 20, 2025
      • Syed Mudasir Ahmad + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 3 0 2 5 2 7
      • eBook
        9 7 8 0 4 4 3 3 0 2 5 3 4
      Encompassing the foundational principles to advanced methodologies, Bioinformatics Essentials: Core Principles and Techniques offers a panoramic view of bioinformatics. It embarks on a journey that spans genes and genomes, sequence analysis, comparative genomics, functional genomics, and the exciting domain of protein structures and drug design. Spread over 3 parts and 7 chapters, the book describes the basic concepts in bioinformatics, genomic analysis, and ligand-based and structure-based drug designs. Each chapter is imbued with real-world context, demonstrating the practical implications of bioinformatics. Case studies, examples, and hands-on guides bridge the gap between theory and application, enabling readers to translate knowledge into tangible results. It fosters a holistic understanding of bioinformatics as an interdisciplinary field, acknowledges the evolving nature of bioinformatics, and prepares the readers for the future. Discussions on emerging trends, cutting-edge tools, and potential directions in the field of bioinformatics equip readers to stay at the forefront of advancements. Insights from both biology and computational science converge to provide a well-rounded perspective on the complex biological systems. While designed as a comprehensive guide for learners, the book also serves as a valuable reference for professionals seeking to deepen their understanding, refine their skills, and explore new avenues within bioinformatics.
    • Geometric Morphometrics for Biologists

      • 3rd Edition
      • November 1, 2025
      • Miriam Zelditch + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 8 9 6 5 1
      • eBook
        9 7 8 0 4 4 3 2 8 9 6 6 8
      Geometric Morphometrics for Biologists: A Primer, Third Edition explores how these geometric methods allow for the study of biological shape by incorporating the geometry of organisms throughout data analyses. Novel content on phylogenetic comparative methods, evolutionary morphology, analyses of disparity, genetics of shape, and simulating shape data is included. This edition delivers step-by-step guidance on how to effectively utilize updated analytical software while also providing guidance on important methodologies that remain relevant to the field to ensure clear and effective instruction to audiences new to this branch of data analysis.It succeeds the second edition as the primary resource for teaching modern geometric methods of shape analysis to students, researchers, and practicing scientists in the field of organismal biology. Users will find it to be an immensely valuable introduction for students and practicing biologists interested in learning applications of multivariate statistics and matrix algebra to organismal biology.
    • Placebo Effects in Neurology

      • 1st Edition
      • Volume 213
      • December 1, 2025
      • Fabrizio Benedetti + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 8 8 4 4
      • eBook
        9 7 8 0 4 4 3 2 9 8 8 5 1
      Placebo Effects in Neurology delves into the intriguing phenomenon of placebos and their profound impact on neurological disorders. This book explores how placebo effects, occurring both in clinical trials and real-world practice, influence therapeutic outcomes, doctor-patient relationships, and symptom perception. The content provides insights into psychobiological mechanisms and specific conditions such as Parkinson’s disease and migraine while addressing ethical and methodological concerns. With discussions on both deceptive and open-label placebos, the book invites readers to reconsider the potential of this underappreciated tool in neurology, offering a bridge between scientific research and practical application in the treatment of various conditions.Beyond its focus on placebo mechanisms, the book examines their role in alleviating symptoms of neuropathic pain, peripheral neuropathies, fatigue, and neuropsychiatric disorders like depression and anxiety. It also presents a methodological lens on how placebos are used to validate treatments in trials while debating their ethical implications. By weaving together science, ethics, and practical insights, Placebo Effects in Neurology stands out as a compelling resource for clinicians, researchers, and anyone interested in the nuanced intersection of psychology and neurology.
    • Drug Metabolism in Diseases

      • 2nd Edition
      • December 1, 2025
      • Wen Xie
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 2 8 9 7
      • eBook
        9 7 8 0 4 4 3 2 9 2 9 0 3
      Drug Metabolism in Diseases: Leveraging Drug Metabolism and Disposition in Precision Medicine and Therapeutic Development, Second Edition provides essential knowledge for pharmaceutical scientists and biologists to understand the interplay between diseases and physiological conditions, impacting drug metabolism and its implications in personalized treatment. Expanded with six new chapters since the first edition, this updated book covers the latest scientific findings. Other important points include the book’s comprehensive reference on mutual effects between drug metabolism and diseases, implications in precision medicine, and therapeutic development. Pharmaceutical scientists, drug metabolism researchers, and research physicians will benefit from the expert insights provided.
    • Whole Cell Biocatalysis

      • 1st Edition
      • April 16, 2025
      • Sergio Huerta-Ochoa + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 3 9 9 8 4
      • eBook
        9 7 8 0 4 4 3 2 3 9 9 9 1
      Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.