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Elsevier

Books in Life sciences

  • Healthgrain Methods

    Analysis of Bioactive Components in Small Grain Cereals
    • 1st Edition
    • Peter Shrewry
    • English
    The explosion of interest around the health benefits of whole grains has led to a new focus on the bioactive components of cereals, including their location and physiological effects. Grains are an important source of minerals (notably selenium, iron and zinc) and vitamins, such as folate. These nutrients are often degraded or removed by the milling or polishing of the grain to provide refined products. Measurements of these components require methodologies for analysis that must be accurate and reproducible and that provide adequate samples to allow wide screening. The work of the 47 prominent international food scientists presented in this comprehensive volume is the direct result of the European Union’s Framework 6 HEALTHGRAIN program which focuses on the role of wholegrain cereals in reducing the risk of metabolic syndrome-related diseases. The development of routine analytical methods for this group of essential phytochemical and dietary fiber components will help food companies improve the health benefits of their products as well as their abilities to measure the bioactive ingredients in cereal-based foods.

  • Nanobiomaterials in Galenic Formulations and Cosmetics

    Applications of Nanobiomaterials
    • 1st Edition
    • Alexandru Grumezescu
    • English
    Nanobiomaterials in Galenic Formulations and Cosmetics: Applications of Nanobiomaterials is one of the first books on the market related to the application of nanotechnology in galenic formulations and cosmetics. This book provides the results of current research for those working in an applied setting. The advantage of having all this information in one coherent text is the focused nature of the chapters and the ease of which this information can be accessed. This collection of titles brings together many of the novel applications these materials have in biology, and discusses the advantages and disadvantages of each application and the perspectives of the technologies based on these findings. At the moment there is no other comparable book series covering all the subjects approached in this set of titles.

  • Sex Differences in Physiology

    • 1st Edition
    • Gretchen Neigh + 1 more
    • English
    Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available.

  • Translational Neuroimmunology in Multiple Sclerosis

    From Disease Mechanisms to Clinical Applications
    • 1st Edition
    • Ruth Arnon + 1 more
    • English
    Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development.

  • Biochar Application

    Essential Soil Microbial Ecology
    • 1st Edition
    • T. Komang Ralebitso-Senior + 1 more
    • English
    Biochar Application: Essential Soil Microbial Ecology outlines the cutting-edge research on the interactions of complex microbial populations and their functional, structural, and compositional dynamics, as well as the microbial ecology of biochar application to soil, the use of different phyto-chemical analyses, possibilities for future research, and recommendations for climate change policy. Biochar, or charcoal produced from plant matter and applied to soil, has become increasingly recognized as having the potential to address multiple contemporary concerns, such as agricultural productivity and contaminated ecosystem amelioration, primarily by removing carbon dioxide from the atmosphere and improving soil functions. Biochar Application is the first reference to offer a complete assessment of the various impacts of biochar on soil and ecosystems, and includes chapters analyzing all aspects of biochar technology and application to soil, from ecogenomic analyses and application ratios to nutrient cycling and next generation sequencing. Written by a team of international authors with interdisciplinary knowledge of biochar, this reference will provide a platform where collaborating teams can find a common resource to establish outcomes and identify future research needs throughout the world.

  • Atlas of Histology of the Juvenile Rat

    • 1st Edition
    • George A Parker + 1 more
    • English
    Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42.

  • Pediatric Brain Stimulation

    Mapping and Modulating the Developing Brain
    • 1st Edition
    • Adam Kirton + 1 more
    • English
    Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain presents the latest on this rapidly expanding field that has seen an exponential growth in publications over the past 10 years. Non-invasive modalities like TMS can painlessly map and measure complex neurophysiology in real patients. Neuromodulatory applications like rTMS and tDCS carry increasingly proven therapeutic applications. Rapidly advancing technological methodologies are increasing opportunities and indications. Despite all these benefits, applications in the more plastic developing brains of children are only just emerging. This book provides a comprehensive overview of brain stimulation in children. Chapters include Transcranial Magnetic Stimulation (TMS) fundamentals, brain stimulation in pediatric neurological conditions, and invasive brain stimulation. The main audience for this research will be those interested in applying brain stimulation technologies to advance clinical research and patient care, although a wide variety of clinicians and scientist will find this to be a valuable reference on brain stimulation with specific chapters on a variety of conditions.

  • Mustard Lung

    Diagnosis and Treatment of Respiratory Disorders in Sulfur-Mustard Injured Patients
    • 1st Edition
    • Mostafa Ghanei + 1 more
    • English
    Mustard Lung: Diagnosis and Treatment of Respiratory Disorders in Sulfur-Mustard Injured Patients brings together the details regarding pathophysiology, medication, and protective issues to provide a comprehensive look at health problems associated with sulfur mustard injury. It provides a bench-to-bedside look at the long term complications of vesicant exposure in humans as well as how mustard gas exposure affects lung function. By providing guidelines and approaches for the diagnosis, pathogenesis, and treatment of SM injury cases, this book is helpful for a wide range of medical researchers and clinicians. For decades, chemical respiratory disorders were diagnosed and managed traditionally similar to other chronic respiratory diseases. However, the exact nature of chemical respiratory disorders is different and needs to be treated as such.

  • Congenital Heart Disease and Neurodevelopment

    Understanding and Improving Outcomes
    • 1st Edition
    • Christopher McCusker + 1 more
    • English
    Congenital Heart Disease and Neurodevelopment: Understanding and Improving Outcomes brings together the work of leading researchers from the U.K., Europe, and the U.S. to provide a comprehensive examination of the causes, risks, and neurodevelopmental and psychological outcomes in children with congenital heart disease. The book includes longitudinal studies which have tracked outcomes from birth through late childhood and explores the emergent phenotype and etiologies, risk, and protective factors that strengthen proposed models. Medical and surgical advances have meant that greater numbers of children with even the most severe congenital heart disease (CHD) now survive well into adulthood. Studies over the past 20 years have suggested certain neurodevelopmental and psychological features are common, with clinical interventions being internationally articulated. The U.K. Belfast Center has developed and evaluated unique early intervention programs to circumvent the common problems discerned and promote optimal adjustment and outcomes. The first edition of Congenital Heart Disease and Neurodevelopment: Understanding and Improving Outcomes describes these programs in detail and outlines promising results obtained by researchers worldwide. Such interventions, together with the U.S. consensus statement (Circulation, 2012) on neurodevelopmental screening, hold great promise for clinical interventions.

  • Functional Neuromarkers for Psychiatry

    Applications for Diagnosis and Treatment
    • 1st Edition
    • Juri D. Kropotov
    • English
    Functional Neuromarkers for Psychiatry explores recent advances in neuroscience that have allowed scientists to discover functional neuromarkers of psychiatric disorders. These neuromarkers include brain activation patterns seen via fMRI, PET, qEEG, and ERPs. The book examines these neuromarkers in detail—what to look for, how to use them in clinical practice, and the promise they provide toward early detection, prevention, and personalized treatment of mental disorders. The neuromarkers identified in this book have a diagnostic sensitivity and specificity higher than 80%. They are reliable, reproducible, inexpensive to measure, noninvasive, and have been confirmed by at least two independent studies. The book focuses primarily on the analysis of EEG and ERPs. It elucidates the neuronal mechanisms that generate EEG spontaneous rhythms and explores the functional meaning of ERP components in cognitive tasks. The functional neuromarkers for ADHD, schizophrenia, and obsessive-compulsive disorder are reviewed in detail. The book highlights how to use these functional neuromarkers for diagnosis, personalized neurotherapy, and monitoring treatment results.

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