Books in Life sciences

Medicinal Chemistry and Drug Development

1st Edition
February 5, 2025
Gang Liu
English
Paperback
9 7 8 0 4 4 3 2 7 4 0 2 2
eBook
9 7 8 0 4 4 3 2 7 4 0 3 9

Medicinal Chemistry and Drug Development describes the key events and roles of medicinal chemistry in the discovery and development of lead compounds into drugs, including target identification, which is accomplished by using 30 case studies. This book outlines all the stages of drug development, including the discovery of active compounds, research on the pharmacologicalprope... of molecules, and confirmation of drug targets. The role of the case studies is to show the common factors in the successful development of drugs, thereby showing medicinal chemists how best to explore the scientific pathways when developing new drugs. This makes the book especially relevant for senior university students majoring in pharmaceutical sciences as well as graduate students and researchers.

Targeting Enzymes in the Brain

1st Edition
Volume 102
February 5, 2025
Takashi Tsukamoto
English
Hardback
9 7 8 0 4 4 3 3 4 2 9 2 9
eBook
9 7 8 0 4 4 3 3 4 2 9 3 6

Targeting Enzymes in the Brain series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Handbook of Immunoassay Technologies

2nd Edition
February 4, 2025
Sandeep K. Vashist + 1 more
English
Paperback
9 7 8 0 3 2 3 9 5 5 0 9 6
eBook
9 7 8 0 3 2 3 9 5 5 1 0 2

Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats. The book discusses how advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies that have paved the way for next-generation immunoassays.Revised and updated, the second edition of Handbook of Immunoassay Technologies: Approaches, Performances, and Applications covers all the relevant, timely, and important developments in the field. This edition offers new content on topics such as antibody production for immunodiagnostics, multiplex immunoassays, chemiluminescent immunoassays, immunoassays for newborn screening, and immunoassays of viruses like SARS-CoV-2, HIV, Ebola, and Hepatitis C. The addition of these new topics as well as up-to-date content make the second edition a valuable and comprehensive resource on immunoassays.

The Immunological Synapse Part C

1st Edition
Volume 193
February 4, 2025
Clément Thomas + 1 more
English
Hardback
9 7 8 0 4 4 3 2 1 8 6 8 2
eBook
9 7 8 0 4 4 3 2 1 8 6 9 9

The Immunological Synapse - Part C, Volume 193 in the Methods in Cell Biology series provides state-of-the-art and detailed methods for the study of the T cell, natural killer (NK) cell and B cell immunological synapses. Topics covered in this third volume include tau-STED microscopy for 3D-quantitative colocalization of lytic granule markers, image processing approaches for 3D-analysis of markers and for microtubule remodeling quantification at the immunological synapse, flow cytometry to analyze NK cell-target cell conjugation, imaging flow cytometry to quantify a range of different subcellular processes at the immunological synapse, imaging techniques aimed at quantitatively analyzing B cell immunological synapse formation, quantification of force-mediated antigen extraction in the B cell immune synapse using DNA-based tension sensors, measuring interaction forces between T lymphocytes and their target cells using live microscopy and laminar shear flow chambers, measuring interaction kinetics between T cells and their target tumor cells with optical tweezers, and gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice. Additionally, this volume includes methods to isolate and characterize primary NK cells and enrich the KIR2DL1+ population, and to expand γδ T cells and evaluate their cytotoxicity.

Commercial Pig Farming

1st Edition
January 31, 2025
Anuj Chauhan + 5 more
English
Paperback
9 7 8 0 4 4 3 2 3 7 6 9 0
eBook
9 7 8 0 4 4 3 2 3 7 7 0 6

Commercial Pig Farming: A Guide for Swine Production and Management provides a comprehensive overview of the pig farming sector, which accounts for approximately 35% of meat production globally. Written by authors spanning 25 chapters, this book aims to provide broad coverage on the key aspects of commercial pig farm management including breeding and reproduction, housing, mechanization, feeding, health and welfare, pork processing, marketing, waste management, and circular bioeconomy. The book will move beyond the basics to cover state-of-the art and cutting-edge technologies in the industry, from artificial intelligence tools and smart phone applications for swine health and feeding management, to the latest vaccinations strategies and biosecurity guidelines for pigs.The most complete and current guide to pig farming available on the market, this book will be most useful to progressive farmers, researchers, and graduate and post-graduate students interested in veterinary science, animal agriculture, and meat production and processing. Professionals working in the pig industry and other livestock industry stakeholders will also find this a valuable resource.

Retinoids in Development and Disease

1st Edition
Volume 161
January 29, 2025
Norbert Ghyselinck + 1 more
English
Hardback
9 7 8 0 3 2 3 9 1 7 0 0 1
eBook
9 7 8 0 3 2 3 9 1 7 0 1 8

Retinoids in Development and Disease, Volume 161 in the Current Topics in Developmental Biology series focuses on the role of retinoids during development and disease. Topics covered include Retinoids, Retinol-Binding Protein 2 (RBP2), Retinol-Binding Protein 4 (RBP4): Obesity and Metabolic Disease, Early Retinoic Acid Signaling Organizes the Body Axis and Defines Domains for the Forelimb and Eye, Rethinking Retinoic Acid Self-Regulation: A Signaling Robustness Network Approach, Meiotic initiation in the fetal ovary without retinoic acid receptors: an unforeseen twist, Action of retinoic acid on progenitor cells in the testis, amongst many other topics.Additional sections cover Retinoic acid homeostasis and disease, Redefining the roles of endogenously produced retinoic acid in heart development and regeneration: lessons from genetic models, The Multifaceted Roles of Retinoids in Vision, Eye Development, and Retinal Degenerative Diseases, Essential roles for retinoid signaling in craniofacial development, and much more.

Biostimulants for Improving Reproductive Growth and Crop Yield

1st Edition
January 29, 2025
Shubhpriya Gupta + 2 more
English
Paperback
9 7 8 0 4 4 3 1 3 2 0 7 0
eBook
9 7 8 0 4 4 3 1 3 2 0 8 7

Biostimulants for Improving Reproductive Growth and Crop Yield highlights their importance as a mechanism, specifically for this result. Intended to transform the latest scientific research into practical application, the book focuses on the effects of biostimulants on flower and fruit development and set, early flowering, pollen viability, germination, and other reproductive aspects. It covers a sustainable approach in utilization of these promising biostimulants in agriculture, horticulture, and floriculture for better productivity, and to feed a growing world population.Biostimul... are a group of substances of natural origin and/or microorganisms that offers the potential to reduce the dependency on harmful chemical fertilizers that cause environmental degradation. The application of biostimulants represents one of the most innovative and promising strategies to improve crop productivity.

Exogenous Priming and Engineering of Plant Metabolic and Regulatory Genes

1st Edition
January 29, 2025
Manish Kumar Patel + 3 more
English
Paperback
9 7 8 0 4 4 3 1 3 4 9 0 6
eBook
9 7 8 0 4 4 3 1 3 4 9 1 3

Exogenous Priming and Engineering of Plant Metabolic and Regulatory Genes: Stress Mitigation Strategies in Plants provides insights into metabolic adjustment, their regulation, and the regulatory networks involved in plants responding to stress situations. It contains comprehensive information, combining mechanistic priming and engineering approaches from the conventional to those recently developed. In addition, the book addresses seed priming, tolerance mechanisms, pre-and post-treatment, as well as sensory response, and genetic manipulation. From basic concepts to modern technologies and prevailing policies, readers will find this book useful in enhancing their understanding of the area as well as helping in identifying approaches for future research.

Building a Space-Faring Civilization

1st Edition
January 29, 2025
Michael Schmidt A + 1 more
English
Paperback
9 7 8 0 4 4 3 1 3 8 5 0 8
eBook
9 7 8 0 4 4 3 1 3 8 5 1 5

Building a Space-Faring Civilization: Advancing the Renaissance of Science, Medicine, and Human Performance in Civilian Spaceflight explores an expanding, unique new trajectory for humankind—the settlement of space by civilians. For the first time in history, average humans can contemplate journeys to Earth orbit, the Moon, and Mars with the idea of space settlement as a plausible reality. As the numbers of spacefaring civilians grow, medical personnel will be asked to meet their complex needs through an ever-expanding discipline—space medicine. But this will require a rapidly advancing science to address what some are calling the next great age in space.This book gathers some of the most accomplished thought leaders in the field of human spaceflight today. Collectively, they helped build the international space station (ISS), develop the field of orbital medicine, guide the development of commercial orbital platforms, plan missions to the Moon and Mars, and forge the innovation necessary for the commercial spaceflight industry to thrive today. The result is an exceptional source of wisdom, experience, and insight surrounding the current biomedical, technical, industrial, legal, and social implications of what is emerging as a true renaissance period in human history.

Materials and Components of Biosensors in Healthcare

1st Edition
January 27, 2025
Md Saquib Hasnain + 2 more
English
Paperback
9 7 8 0 4 4 3 2 1 6 7 6 3
eBook
9 7 8 0 4 4 3 2 1 6 7 7 0

Materials and Components of Biosensors in Healthcare: Volume Two provides comprehensive coverage and a detailed examination of the various materials and components used in the development of biosensors. The book begins with an introduction and then discusses the biochemical, inorganic, and biopolymeric components used in biosensor assembly. It goes on to detail a range of materials such as nanoparticles, biological cellular structures, electrochemical, and electromagnetic materials and how they are used in biosensors.Combined with Fundamentals of Biosensors in Healthcare, Volume One, and Applications of Biosensors in Healthcare, Volume Three, this trio provides holistic reference sources suitable for researchers, graduate students, postgraduates, and industry professionals involved in biosensing, biosensors, and biomedical applications.

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