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Books in Life sciences

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    • Sugarcane Improvement Through Breeding

      • 1st Edition
      • Volume 11
      • August 11, 2015
      • D.J Heinz
      • English
      • eBook
        9 7 8 1 4 8 3 2 8 9 9 8 4
      This book is a comprehensive survey of breeding principles and practices employed by sugarcane growers and researchers throughout the world. Included within its scope are important genera and species concepts, morphological information, clarification of certain generic names, a description of germplasm collection and utilization, discussion of the complex issues involved in genetic manipulation, and a summary of sugarcane improvement through breeding over the past century.The book is compiled so that information proceeds from the general to the specific. Basic concepts of evolution, taxonomy, morphology, and anatomy form the groundwork for information regarding germplasm collection, cyto-genetics, genetics, and flowering. Methods of practical application are presented in the ensuing chapters, which deal with hybridization, tissue culture, seed handling, selection criteria, and breeding for tolerance. Figures, tables, and photographs accompany text where appropriate. All key words are indexed and extensive bibliographies follow each chapter.

    • Stellate Cells in Health and Disease

      • 1st Edition
      • April 8, 2015
      • Chandrashekhar Gandhi + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 1 3 4 9
      • eBook
        9 7 8 0 1 2 8 0 0 5 4 4 6
      Stellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology.

    • Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology

      • 1st Edition
      • August 7, 2015
      • Hamid R Arabnia + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 2 5 0 8 6
      • eBook
        9 7 8 0 1 2 8 0 2 6 4 6 5
      Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques. • Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid computing for the storage and access of big data sets. • Presents a systematic approach for storing, retrieving, organizing, and analyzing biological data using software tools with applications to general principles of DNA/RNA structure, bioinformatics and applications, genomes, protein structure, and modeling and classification, as well as microarray analysis. • Provides a systems biology perspective, including general guidelines and techniques for obtaining, integrating, and analyzing complex data sets from multiple experimental sources using computational tools and software. Topics covered include phenomics, genomics, epigenomics/epigenet... metabolomics, cell cycle and checkpoint control, and systems biology and vaccination research. • Explains how to effectively harness the power of Big Data tools when data sets are so large and complex that it is difficult to process them using conventional database management systems or traditional data processing applications.

    • Comparative Biology of the Normal Lung

      • 2nd Edition
      • March 13, 2015
      • Richard A. Parent
      • English
      • Hardback
        9 7 8 0 1 2 4 0 4 5 7 7 4
      • eBook
        9 7 8 0 1 2 4 0 4 7 2 6 6
      Comparative Biology of the Normal Lung, Second Edition, offers a rigorous and comprehensive reference for all those involved in pulmonary research. This fully updated work is divided into sections on anatomy and morphology, physiology, biochemistry, and immunological response. It continues to provide a unique comparative perspective on the mammalian lung. This edition includes several new chapters and expanded content, including aging and development of the normal lung, mechanical properties of the lung, genetic polymorphisms, the comparative effect of stress of pulmonary immune function, oxygen signaling in the mammalian lung and much more. By addressing scientific advances and critical issues in lung research, this 2nd edition is a timely and valuable work on comparative data for the interpretation of studies of animal models as compared to the human lung.

    • Streptococcus Pneumoniae

      • 1st Edition
      • May 8, 2015
      • Jeremy Brown + 2 more
      • English
      Streptococcus Pneumoniae: Molecular Mechanisms of Host-Pathogen Interactions provides a comprehensive overview of our existing knowledge on Streptococcus pneumoniae antibiotic resistance, dissemination, and pathogenesis, including immunology. It presents a state-of-the-art overview of the implications of existing data, along with the areas of research that are important for future insights into the molecular mechanisms of pneumococcal infections and how to combat these infections. Users will find a timely update on the topic, as the dramatic increase in antibiotic resistance pneumoniae cases and limitations of the currently available pneumoniae vaccines are creating new concerns on these gram-positive bacteria that are endowed with a high virulence potential, and are the most common etiologic agent of respiratory and life-threatening invasive diseases.

    • Food Safety

      • 1st Edition
      • July 8, 2015
      • Steven Ricke + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 2 4 5 2
      • eBook
        9 7 8 0 1 2 8 0 0 4 0 4 3
      Food Safety: Emerging Issues, Technologies and Systems offers a systems approach to learning how to understand and address some of the major complex issues that have emerged in the food industry. The book is broad in coverage and provides a foundation for a practical understanding in food safety initiatives and safety rules, how to deal with whole-chain traceability issues, handling complex computer systems and data, foodborne pathogen detection, production and processing compliance issues, safety education, and more. Recent scientific industry developments are written by experts in the field and explained in a manner to improve awareness, education and communication of these issues.

    • Principles of Translational Science in Medicine

      • 2nd Edition
      • April 2, 2015
      • Martin Wehling
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 6 8 7 0
      • eBook
        9 7 8 0 1 2 8 0 0 7 2 1 1
      Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine.

    • Nonclinical Assessment of Abuse Potential for New Pharmaceuticals

      • 1st Edition
      • July 14, 2015
      • Carrie Markgraf + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 4 2 0 1 7 2 9
      • eBook
        9 7 8 0 1 2 4 2 0 2 1 6 0
      Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability.

    • The Transformation of Academic Health Centers

      • 1st Edition
      • March 30, 2015
      • Steven Wartman
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 7 6 2 4
      • eBook
        9 7 8 0 1 2 8 0 1 0 0 4 4
      The Transformation of Academic Health Centers: The Institutional Challenge to Improve Health and Well-Being in Healthcare’s Changing Landscape presents the direct knowledge and vision of accomplished academic leaders whose unique positions as managers of some of the most complex academic and business enterprises make them expert contributors. Users will find invaluable insights and leadership perspectives on healthcare, health professions education, and bio-medical and clinical research that systematically explores the evolving role of global academic health centers with an eye focused on the transformation necessary to be successful in challenging environments. The book is divided into five sections moving from the broad perspective of the role of academic health centers to the role of education, training, and disruptive technologies. It then addresses the discovery processes, improving funding models, and research efficiency. Subsequent sections address the coming changes in healthcare delivery and future perspectives, providing a complete picture of the needs of the growing and influential healthcare sector.

    • Chemical Modulators of Protein Misfolding and Neurodegenerative Disease

      • 1st Edition
      • January 12, 2015
      • Pierfausto Seneci
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 9 4 4 3
      • eBook
        9 7 8 0 1 2 8 0 1 9 5 9 7
      This book is a neurochemistry-based companion for Protein Misfolding and Neurodegenerative Diseases: Molecular Targets, an Elsevier title by the same author publishing in December 2014. While the first book focuses on biology and molecular targets, this companion book describes how these targets are regulated by small molecules and disease-modifying compounds. The book begins with a brief introduction to how key proteins become dysfunctional, and each subsequent chapter describes major disease mechanisms in Alzheimer’s and other tauopathies. Properties and development status of these molecular targets and disease mechanisms are thoroughly described, as are small molecule effectors of autophagy and dis-aggregating agents.

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