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Elsevier

Books in Life sciences

  • Micro- and Nanotechnology in Vaccine Development

    • 1st Edition
    • Mariusz Skwarczynski + 1 more
    • English
    This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles.

  • An Introduction to Field Quantization

    International Series of Monographs in Natural Philosophy
    • 1st Edition
    • Y. Takahashi
    • D. ter Haar
    • English
    An Introduction to Field Quantization is an introductory discussion of field quantization and problems closely related to it. Field quantization establishes a commutation relation of the field and finds an operator in such a manner that the Heisenberg equation of motion is satisfied. This book contains eight chapters and begins with a review of the quantization of the Schroedinger field and the close relation between quantized field theory and the many-body theory in quantum mechanics. These topics are followed by discussions of the quantization of the radiation field and the field of lattice vibrations in a solid. The succeeding chapter deals with the familiar linear equations in relativistic field theory and the deduction of certain spin independent theories, which these fields have in common. Other chapter explores the derivation technique of the conservation laws for fields with arbitrary spin directly from the field equations without explicit recourse to Noether's theorem using a configuration space version of the generalized Ward identity. The discussion then shifts to the relativistic quantization method applicable to any field with arbitrary spin; the transformation of various fields under the Lorentz transformation; and a general method for constructing wave functions explicitly, as well as the application of this method to several examples. The concluding chapter focuses on the quantization of interacting fields. This book will prove useful to physicists and researchers.

  • Network Neuroscience

    • 1st Edition
    • Flavio Fröhlich
    • English
    Studying brain networks has become a truly interdisciplinary endeavor, attracting students and seasoned researchers alike from a wide variety of academic backgrounds. What has been lacking is an introductory textbook that brings together the different fields and provides a gentle introduction to the major concepts and findings in the emerging field of network neuroscience. Network Neuroscience is a one-stop-shop that is of equal use to the neurobiologist, who is interested in understanding the quantitative methods employed in network neuroscience, and to the physicist or engineer, who is interested in neuroscience applications of mathematical and engineering tools. The book spans 27 chapters that cover everything from individual cells all the way to complex network disorders such as depression and autism spectrum disorders. An additional 12 toolboxes provide the necessary background for making network neuroscience accessible independent of the reader’s background. Dr. Flavio Frohlich wrote this book based on his experience of mentoring dozens of trainees in the Frohlich Lab, from undergraduate students to senior researchers. The Frohlich lab pursues a unique and integrated vision that combines computer simulations, animal model studies, human studies, and clinical trials with the goal of developing novel brain stimulation treatments for psychiatric disorders. The book is based on a course he teaches at UNC that has attracted trainees from many different departments, including neuroscience, biomedical engineering, psychology, cell biology, physiology, neurology, and psychiatry. Dr. Frohlich has consistently received rave reviews for his teaching. With this book he hopes to make his integrated view of neuroscience available to trainees and researchers on a global scale. His goal is to make the book the training manual for the next generation of (network) neuroscientists, who will be fusing biology, engineering, and medicine to unravel the big questions about the brain and to revolutionize psychiatry and neurology.

  • Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders

    Alzheimer's Disease
    • 1st Edition
    • Adeboye Adejare
    • English
    Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders.

  • Developing New Functional Food and Nutraceutical Products

    • 1st Edition
    • Debasis Bagchi + 1 more
    • English
    Developing New Functional Food and Nutraceutical Products provides critical information from conceptualization of new products to marketing, aiming to present a solid understanding of the entire process through detailed coverage of key concepts, namely innovation, regulation, manufacturing, quality control, and marketing. Chapters provide insights into market and competitive analysis, product design and development, intellectual property, ingredient sourcing, cost control, and sales and marketing strategies.

  • Translating MicroRNAs to the Clinic

    • 1st Edition
    • Jeffrey Laurence
    • English
    Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books on the topic. In addition, the book emphasizes recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.

  • Current Developments in Biotechnology and Bioengineering

    Foundations of Biotechnology and Bioengineering
    • 1st Edition
    • Ashok Pandey + 1 more
    • English
    Current Developments in Biotechnology and Bioengineering: Foundations of Biotechnology and Bioengineering is a package of nine books that compile the latest ideas from across the entire arena of biotechnology and bioengineering. This volume focuses on the underlying principles of biochemistry, microbiology, fermentation technology, and chemical engineering as interdisciplinary themes, constructing the foundation of biotechnology and bioengineering.

  • Current Developments in Biotechnology and Bioengineering

    Biological Treatment of Industrial Effluents
    • 1st Edition
    • Duu-Jong Lee + 4 more
    • English
    Current Developments in Biotechnology and Bioengineering: Biological Treatment of Industrial Effluents provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends in data-based scientific knowledge and advanced information on the role and application of environmental biotechnology and engineering in the treatment of industrial effluents. These treatment processes have been broadly classified under aerobic and anaerobic processes which determines the scope and level of pollutant removal. Chapters in this volume review the most recent developments and perspectives at different environmental cleanup operation scales.

  • Current Developments in Biotechnology and Bioengineering

    Crop Modification, Nutrition, and Food Production
    • 1st Edition
    • Suresh Kumar Dubey + 2 more
    • English
    Current Developments in Biotechnology and Bioengineering: Crop Modification, Nutrition, and Food Production provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, presenting data-based scientific knowledge on agribiotechnology and describing world agriculture and the role biotechnology can play in ensuring food security over the next fifty years. The book discusses the effects of climate change in agriculture and the resultant emergence of new crops, including drought tolerant and more nutritious plants. In addition, the book discusses insect and virus resistance in plants and outlines plant metabolic engineering for agriculture, genetically engineered plants, and microbial diseases.

  • Current Developments in Biotechnology and Bioengineering

    Human and Animal Health Applications
    • 1st Edition
    • Vanete Thomaz Soccol + 2 more
    • English
    Current Developments in Biotechnology and Bioengineering: Human and Animal Health Applications provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, presenting data-based scientific knowledge and information on medical biotechnological interventions for human and animal health. Drawing on the key development areas in this field, the book reviews biotechnological advances and applications in immunotechnology, vaccines and vaccinology, combinatorial libraries, gene and cell therapy, tissue engineering, and parasite and infectious disease diagnostics. This title outlines why biotechnological techniques in these areas are useful in a clinical context and considers their potential uses, limitations, and the ethical considerations surrounding their use.

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