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Books in Life sciences

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    • PCR Guru

      • 1st Edition
      • November 28, 2016
      • Ayaz Najafov + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 4 2 3 1 1
      • eBook
        9 7 8 0 1 2 8 0 4 2 4 6 5
      PCR Guru: An Ultimate Benchtop Reference for Molecular Biologists is provides researchers in molecular biology with a handy reference for approaching and solving challenging problems associated with PCR setup and optimization. As a laboratory guide, it emphasizes the technical aspects of employing PCR as a tool in molecular biology laboratories. The book covers the history of PCR and the basic science underlying it. It then discusses PCR at the bench level, starting with detailed description and tips on primer design, and continuing with the standard protocols used to perform PCR.

    • Hyperpolarized and Inert Gas MRI

      • 1st Edition
      • November 17, 2016
      • Mitchell S. Albert + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 6 7 5 4
      • eBook
        9 7 8 0 1 2 8 0 3 7 0 4 1
      Hyperpolarized and Inert Gas MRI: Theory and Applications in Research and Medicine is the first comprehensive volume published on HP gas MRI. Since the 1990’s, when HP gas MRI was invented by Dr. Albert and his colleagues, the HP gas MRI field has grown dramatically. The technique has proven to be a useful tool for diagnosis, disease staging, and therapy evaluation for obstructive lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. HP gas MRI has also been developed for functional imaging of the brain and is presently being developed for molecular imaging, including molecules associated with lung cancer, breast cancer, and Alzheimer’s disease. Taking into account the ongoing growth of this field and the potential for future clinical applications, the book pulls together the most relevant and cutting-edge research available in HP gas MRI into one resource.

    • Eye Diseases in Hot Climates

      • 2nd Edition
      • June 3, 2016
      • John Sandford-Smith
      • English
      • Paperback
        9 7 8 0 7 2 3 6 2 1 9 5 9
      • eBook
        9 7 8 1 4 8 3 1 8 3 7 2 5
      Eye Diseases in Hot Climates, Second Edition provides information pertinent to the fundamental aspects of eye diseases in hot or tropical countries. This book examines the features of basic eye care, including careful planning, cost effectiveness, mobility, cooperation between various sciences, methods and resources, and an emphasis on prevention. Organized into 20 chapters, this edition begins with an overview of the various causes of eye diseases in hot, tropical, or developing countries. This text then examines the basic structure of the eye, which consists of three layers of tissue, namely, an outer protective layer, a middle layer of blood vessels, pigment cell and muscle fibers, and the retina. Other chapters consider the clinical methods needed to assess a patient with eye disease. This book discusses as well the various types of eye diseases, including, conjunctivitis, corneal ulcers, retinal degenerations, and vascular retinopathies. The final chapter deals with loss of vision. This book is a valuable resource for ophthalmologists.

    • Osteoarchaeology

      • 1st Edition
      • December 22, 2016
      • Efthymia Nikita
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 0 2 1 8
      • eBook
        9 7 8 0 1 2 8 0 4 0 9 7 3
      Osteoarchaeology: A Guide to the Macroscopic Study of Human Skeletal Remains covers the identification of bones and teeth, taphonomy, sex, ancestry assessment, age estimation, the analysis of biodistances, growth patterns and activity markers, and paleopathology. The book aims to familiarize the reader with the main applications of osteoarchaeology and provide the necessary knowledge required for the implementation of a broad range of osteological methods. It is ideal as a complement to existing textbooks used in upper level undergraduate and graduate courses on osteoarchaeology, human osteology, and, to some extent, forensic anthropology. Pedagogical features include ample illustrations, case study material, revision exercises, and a glossary. Additional features comprise macros that facilitate data processing and analysis, as well as an extensive chapter on applied statistics.

    • Polymers and Nanomaterials for Gene Therapy

      • 1st Edition
      • January 9, 2016
      • Ravin Narain
      • English
      • Hardback
        9 7 8 0 0 8 1 0 0 5 2 0 0
      • eBook
        9 7 8 0 0 8 1 0 0 5 2 1 7
      Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy.

    • Neuroimaging, Part I

      • 1st Edition
      • Volume 135
      • July 12, 2016
      • English
      • Hardback
        9 7 8 0 4 4 4 5 3 4 8 5 9
      • eBook
        9 7 8 0 7 0 2 0 4 5 3 7 0
      Neuroimaging, Part One, a text from The Handbook of Clinical Neurology illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This first volume specifically covers a description of imaging techniques used in the adult brain, aiming to bring a comprehensive view of the field of neuroimaging to a varying audience. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, and the entire field is moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to this new horizon in the study of neurological disorders.

    • The Auditory System and Human Sound-Localization Behavior

      • 1st Edition
      • March 29, 2016
      • John van Opstal
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 5 2 9 2
      • eBook
        9 7 8 0 1 2 8 0 1 7 2 5 8
      The Auditory System and Human Sound-Localization Behavior provides a comprehensive account of the full action-perception cycle underlying spatial hearing. It highlights the interesting properties of the auditory system, such as its organization in azimuth and elevation coordinates. Readers will appreciate that sound localization is inherently a neuro-computational process (it needs to process on implicit and independent acoustic cues). The localization problem of which sound location gave rise to a particular sensory acoustic input cannot be uniquely solved, and therefore requires some clever strategies to cope with everyday situations. The reader is guided through the full interdisciplinary repertoire of the natural sciences: not only neurobiology, but also physics and mathematics, and current theories on sensorimotor integration (e.g. Bayesian approaches to deal with uncertain information) and neural encoding.

    • Systemic Inflammatory Disease and the Eye

      • 1st Edition
      • August 19, 2016
      • W. J. Dinning
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 7 7 0 0
      • eBook
        9 7 8 1 4 8 3 1 9 3 5 1 9
      Systemic Inflammatory Disease and the Eye present an overview of the systemic conditions associated with ocular inflammation. It discusses the factors for ocular connection in some conditions. It addresses the nature of ocular lesions and eye infections. Some of the topics covered in the book are the symptoms of inflammation of the eye; the aetiology of sarcoidosis; posterior segment inflammation; pathology and immunology of systemic vasculitis syndromes; aetiology of polyarteritis nodosa; diagnosis of systemic lupus erythematosus; and the different types of Sjogren’s syndrome. The pathology and immunopathology of Keratoconjunctivitis Sicca are fully covered. The diagnosis of rheumatoid arthritis is discussed in detail. The text describes in depth the rheumatoid factors and histopathology of joint lesions. The diagnosis of juvenile chronic polyarthritis is presented completely. A chapter is devoted to the epidemiology and clinical features of ankylosing spondylitis. The book can provide useful information to ophthalmologists, doctors, chemists, students, and researchers.

    • The Nature of Disease

      • 1st Edition
      • April 20, 2016
      • J. E. R. McDonagh
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 8 7 3 8
      • eBook
        9 7 8 1 4 8 3 1 9 4 5 4 7
      The Nature of Disease, Part III deals with mal-coordination and disease, disease and the nervous systems, and chronic intestinal intoxication. This book discusses the signs and symptoms of disease which is the result of the body's failure to resist infection. The author sees that dehydration is the prevailing abnormal chemico-physical change in the acute stage of disease attack; hydration in the chronic stage. He notes that these two phenomena occur when protein particles in the plasma in disease undergo either a dehydration or hydration process. The author also reviews F.M. Alexander's work on the conscious control of the individual, through psycho-physical mechanism, as a whole body, instead of being reflected in certain anatomical part such as the kidneys, liver, or skin. The author examines the interrelationships between mal-coordination and the nervous system. Such mal-coordination results in chronic intestinal intoxication on nervous manifestations; the author then demonstrates how nerve tissues are damaged by abnormal protein particles in the plasma. The author cites several cases of mal-coordination concerning the nervous system, the vegetative nervous system and the alimentary tract, as well as the role played by a chronic intestinal intoxication in the invasion of the nervous system by micro-organisms. This book can prove informative for cellular biologists, researchers in micro-chemistry or neuro-biology, and doctors in general practice.

    • Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods

      • 1st Edition
      • Volume 105
      • August 24, 2016
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 8 2 5 2
      • eBook
        9 7 8 0 1 2 8 0 5 2 4 1 9
      Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

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