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Books in Life sciences

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    • Astrocytes and Epilepsy

      • 1st Edition
      • July 5, 2016
      • Jacqueline A. Hubbard + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 4 0 1 0
      • eBook
        9 7 8 0 1 2 8 0 2 6 2 4 3
      Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy.

    • Mesenchymal Stromal Cells

      • 1st Edition
      • August 9, 2016
      • Hematti Peiman + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 2 8 2 6 1
      • eBook
        9 7 8 0 1 2 8 0 2 8 4 0 7
      Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues, it is a useful guide for researchers and administrators across biomedical research.

    • Cushing's Disease

      • 1st Edition
      • November 8, 2016
      • Edward R. Laws Jr + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 4 3 4 0 0
      • eBook
        9 7 8 0 1 2 8 0 4 3 9 0 5
      Cushing’s Disease: An Often Misdiagnosed and Not So Rare Disorder reviews the epidemiology of Cushing’s, including statistics on the incidence and prevalence of this disease. There are discussions of the signs and symptoms and the most common co-morbidities, such as diabetes mellitus, hypertension, osteoporosis, amenorrhea, and infertility. Surgical, medical, and radiotherapeutic treatments, including indications, results, risks, and complications, are reviewed. Also featured is a chapter on the patient’s perspective, coping with Cushing’s, quality of life, and psychosomatic issues. This book is essential reading for the wide range of physicians who treat patients with Cushing’s disease symptoms, as well as biomedical researchers who investigate the etiology and mechanisms of rare genetic diseases, in particular rare endocrine disorders.

    • Life-Cycle Assessment of Biorefineries

      • 1st Edition
      • December 20, 2016
      • Edgard Gnansounou + 1 more
      • English
      • Hardback
        9 7 8 0 4 4 4 6 3 5 8 5 3
      • eBook
        9 7 8 0 4 4 4 6 3 5 8 6 0
      Life-Cycle Assessment of Biorefineries, the sixth and last book in the series on biomass-biorefinerie... discusses the unprecedented growth and development in the emerging concept of a global bio-based economy in which biomass-based biorefineries have attained center stage for the production of fuels and chemicals. It is envisaged that by 2020 a majority of chemicals currently being produced through a chemical route will be produced via a bio-based route. Agro-industrial residues, municipal solid wastes, and forestry wastes have been considered as the most significant feedstocks for such bio-refineries. However, for the techno-economic success of such biorefineries, it is of prime and utmost importance to understand their lifecycle assessment for various aspects.

    • Dictionary of Nutrition and Food Technology

      • 5th Edition
      • July 29, 2016
      • Arnold E. Bender
      • English
      • Paperback
        9 7 8 1 4 8 3 1 0 6 4 2 7
      • eBook
        9 7 8 1 4 8 3 1 0 0 0 8 1
      Dictionary of Nutrition and Food Technology: Fifth Edition defines technical terms, jargons, and abbreviations used in the field of nutrition and food technology. The guide contains over 250 new terms included, 350 terms revised, and obsolete terms retained as well. The book also contains a bibliography of 180 subjects, as well as tables for recommended intakes, dietary allowances, and energy and protein content of edible portions. The text is recommended for those who are new to the field and are still unfamiliar with the terminologies, as well as for experts who need a quick reference.

    • Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

      • 1st Edition
      • June 7, 2016
      • Thomas Lehner + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 1 0 5 9
      • eBook
        9 7 8 0 1 2 8 0 0 5 3 0 9
      This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders.

    • Proteomic Profiling and Analytical Chemistry

      • 2nd Edition
      • March 2, 2016
      • Pawel Ciborowski + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 6 3 6 8 8 1
      • eBook
        9 7 8 0 4 4 4 6 3 6 9 0 4
      Proteomic Profiling and Analytical Chemistry: The Crossroads, Second Edition helps scientists without a strong background in analytical chemistry to understand principles of the multistep proteomic experiment necessary for its successful completion. It also helps researchers who do have an analytical chemistry background to break into the proteomics field. Highlighting points of junction between proteomics and analytical chemistry, this resource links experimental design with analytical measurements, data analysis, and quality control. This targeted point of view will help both biologists and chemists to better understand all components of a complex proteomic study. The book provides detailed coverage of experimental aspects such as sample preparation, protein extraction and precipitation, gel electrophoresis, microarrays, dynamics of fluorescent dyes, and more. The key feature of this book is a direct link between multistep proteomic strategy and quality control routinely applied in analytical chemistry. This second edition features a new chapter on SWATH-MS, substantial updates to all chapters, including proteomic database search and analytical quantification, expanded discussion of post-hoc statistical tests, and additional content on validation in proteomics.

    • Advances in Cancer Research

      • 1st Edition
      • Volume 130
      • March 29, 2016
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 7 8 9 7
      • eBook
        9 7 8 0 1 2 8 0 5 1 8 1 8
      Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research, presenting outstanding and original reviews on a variety of topics.

    • Molecular Diagnostics

      • 3rd Edition
      • October 27, 2016
      • George P. Patrinos + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 9 7 1 8
      • eBook
        9 7 8 0 1 2 8 0 2 9 8 8 6
      Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter. Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies. All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor. The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management.

    • Wheat Flour

      • 2nd Edition
      • September 28, 2016
      • William A Atwell + 1 more
      • English
      • Paperback
        9 7 8 1 8 9 1 1 2 7 9 0 8
      • eBook
        9 7 8 0 1 2 8 1 2 3 6 6 9

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