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Books in Life sciences

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    • Patient Derived Tumor Xenograft Models

      • 1st Edition
      • October 13, 2016
      • Rajesh Uthamanthil + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 4 0 1 0 2
      • eBook
        9 7 8 0 1 2 8 0 4 0 6 1 4
      Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory.

    • Flavor

      • 1st Edition
      • May 26, 2016
      • Patrick Etiévant + 3 more
      • English
      • Hardback
        9 7 8 0 0 8 1 0 0 2 9 5 7
      • eBook
        9 7 8 0 0 8 1 0 0 3 0 0 8
      Flavor: From Food to Behaviors, Wellbeing and Health is the first single-volume resource focused on the different mechanisms of flavor perception from food ingestion, to sensory image integration and the physiological effects that may explain food behaviors. The information contained is highly multidisciplinary, starting with chemistry and biochemistry, and then continuing with psychology, neurobiology, and sociology. The book gives coherence between results obtained in these fields to better explain how flavor compounds may modulate food intake and behavior. When available, physiological mechanisms and mathematical models are explained. Since almost half a billion people suffer from obesity and food related chronic diseases in the world, and since recent research has investigated the possible roles of pleasure linked to the palatability of food and eating pleasure on food intake, food habits, and energy regulation, this book is a timely resource on the topic. This book links these results in a logical story, starting in the food and the food bolus, and explaining how flavor compounds can reach different receptors, contribute to the emergence of a sensory image, and modulate other systems recognized as controlling food intake and food behavior. The influence of age, physiological disorders, or social environments are included in this approach since these parameters are known to influence the impact of food flavor on human behavior.

    • Lanzkowsky's Manual of Pediatric Hematology and Oncology

      • 6th Edition
      • April 22, 2016
      • Jonathan D. Fish + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 3 6 8 7
      • eBook
        9 7 8 0 1 2 8 0 1 6 7 4 9
      Lanzkowsky’s Manual of Pediatric Hematology and Oncology, Sixth Edition, is a comprehensive book on patient management, replete with algorithms and flow diagrams on diagnosis and management. Reflecting the considerable advances in the treatment and management of hematologic and oncologic diseases in children, the sixth edition of this successful clinical manual has been entirely updated to incorporate all current treatment protocols, new drugs, and management approaches. Its concise and easy-to-read format will enable readers to make accurate diagnoses and permit them to treat patients without having to reference larger medical textbooks. Based on the new standards of genetic classification and prognostic information that have arisen in the past five years, the sixth edition includes two new chapters (Diagnostic, Molecular, and Genomic Methodologies for the Hematologist, Transfusion Medicine) and several new expanded chapters that were previously sections in consolidated chapters (Myelodysplasia, Myeloid Leukemias, Lymphoid Leukemias, Hemolytic Anemia, and Disorders of Coagulation).

    • Artificial Photosynthesis

      • 1st Edition
      • Volume 79
      • June 13, 2016
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 2 8 9 3
      • eBook
        9 7 8 0 1 2 8 0 3 3 2 5 8
      Artificial Photosynthesis, the latest edition in the Advances in Botanical Research series, which publishes in-depth and up-to-date reviews on a wide range of topics in the plant sciences features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology, and ecology.

    • Gene-Environment Interactions in Psychiatry

      • 1st Edition
      • July 26, 2016
      • Bart Ellenbroek + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 1 6 5 7 2
      • eBook
        9 7 8 0 1 2 8 0 1 7 8 3 8
      Gene-Environment Interactions in Psychiatry: Nature, Nurture, Neuroscience begins with the basic aspects of gene–environment studies, such as basic genetics, principles of animals modeling, and the basic processes of how environmental factors affect brain and behavior, with part two describing the most important psychiatric disorders in detail. Each chapter has a similar structure that includes a general description of the disorder that is followed by an analysis of the role of genes and how they are affected by environmental factors. Each chapter ends with a description of the most relevant animal models, again focusing on gene–environment interactions. The book concludes with a critical evaluation of the current research and an outlook for the (possible) future, offering a vignette into the fascinating world of nature, nurture, and neuroscience.

    • Current Developments in Biotechnology and Bioengineering

      • 1st Edition
      • September 15, 2016
      • Suresh Kumar Dubey + 2 more
      • English
      • Hardback
        9 7 8 0 4 4 4 6 3 6 6 1 4
      • eBook
        9 7 8 0 4 4 4 6 3 6 7 2 0
      Current Developments in Biotechnology and Bioengineering: Crop Modification, Nutrition, and Food Production provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, presenting data-based scientific knowledge on agribiotechnology and describing world agriculture and the role biotechnology can play in ensuring food security over the next fifty years. The book discusses the effects of climate change in agriculture and the resultant emergence of new crops, including drought tolerant and more nutritious plants. In addition, the book discusses insect and virus resistance in plants and outlines plant metabolic engineering for agriculture, genetically engineered plants, and microbial diseases.

    • Encyclopedia of Evolutionary Biology

      • 1st Edition
      • April 14, 2016
      • Richard M Kliman
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 0 4 9 6
      • eBook
        9 7 8 0 1 2 8 0 0 4 2 6 5
      • eBook
        9 7 8 0 1 2 8 0 9 6 8 8 8
      Encyclopedia of Evolutionary Biology, Four Volume Set is the definitive go-to reference in the field of evolutionary biology. It provides a fully comprehensive review of the field in an easy to search structure. Under the collective leadership of fifteen distinguished section editors, it is comprised of articles written by leading experts in the field, providing a full review of the current status of each topic. The articles are up-to-date and fully illustrated with in-text references that allow readers to easily access primary literature. While all entries are authoritative and valuable to those with advanced understanding of evolutionary biology, they are also intended to be accessible to both advanced undergraduate and graduate students. Broad topics include the history of evolutionary biology, population genetics, quantitative genetics; speciation, life history evolution, evolution of sex and mating systems, evolutionary biogeography, evolutionary developmental biology, molecular and genome evolution, coevolution, phylogenetic methods, microbial evolution, diversification of plants and fungi, diversification of animals, and applied evolution.

    • Understanding PCR

      • 1st Edition
      • October 26, 2016
      • Sarah Maddocks + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 2 6 8 3 0
      • eBook
        9 7 8 0 1 2 8 0 2 6 9 7 7
      Understanding PCR: A Practical Bench-Top Guide gives you all of the information you need to plan your first PCR, from reagents to conditions to analysis and beyond. It is a user friendly book that has step-by-step basic protocols, which can be adapted to your needs. Includes helpful information such as where to order your reagents and basic troubleshooting hints and tips.

    • Thresholds of Genotoxic Carcinogens

      • 1st Edition
      • May 20, 2016
      • Takehiko Nohmi + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 6 6 3 3
      • eBook
        9 7 8 0 1 2 8 0 1 8 0 3 3
      Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation brings together current opinion and research activities from Japan, the US, and Europe on the subject of genotoxic thresholds. In regulation, it is an adage that genotoxic carcinogens have no thresholds for action, and that they impose cancer risk on humans even at very low levels. This policy is frequently called into question as humans possess a number of defense mechanisms including detoxication, DNA repair, and apoptosis, meaning there is a threshold at which these genotoxic carcinogens take action. The book examines these potential thresholds, describing the potential cancer risks of daily low-level exposure, the mechanisms involved (such as DNA repair, detoxication, translesion DNA synthesis), chemical and statistical methods of analysis, and the ways in which these may be utilized to inform policy. Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation is an essential reference for any professional researchers in genetic toxicology and those involved in toxicological regulation.

    • Linked by Blood: Hemophilia and AIDS

      • 1st Edition
      • May 19, 2016
      • David Green
      • English
      • Paperback
        9 7 8 0 1 2 8 0 5 3 0 2 7
      • eBook
        9 7 8 0 1 2 8 0 5 4 4 7 5
      Linked by Blood: Hemophilia and AIDS recounts the factors responsible for the widespread infection of people with hemophilia by Human Immunodeficiency Virus (HIV)-contaminated blood and offers a prescription for addressing the challenges of future viral epidemics. The book describes the impact of AIDS on people with hemophilia, their families, and caregivers. The collection, processing, and distribution of blood in the early years of the HIV epidemic are described, including the failure of regulatory agencies to promulgate effective rules to safeguard the blood supply. The contributions of individuals and organizations that mitigated the epidemic are recognized. Linked by Blood presents recommendations for addressing the myriad medical, social, and economic challenges posed by blood-borne viral infections (AIDS, Ebola, MERS) that periodically sweep through large segments of our population.

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