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    • Economic Evaluation of Pharmacy Services

      • 1st Edition
      • October 13, 2016
      • Zaheer-Ud-Din Babar
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 6 5 9 4
      • eBook
        9 7 8 0 1 2 8 0 3 7 0 0 3
      Economic Evaluation of Pharmacy Services provides the latest on the trend to a more product-centered and service-centered practice, eschewing traditional economic evaluation techniques that focus on product-to-product comparisons in favor of evaluating processes that measure costs and health outcomes. Complete with examples focusing on best practices, including various study designs, types of pharmacy services, and types of outcomes being evaluated, the book emphasizes case studies and examples that help readers understand economic evaluation techniques. Many of these techniques are transferable across countries, especially where there are advanced and stable health systems in place. With the help of this practical guide, readers will gain a thorough understanding of the application of economic evaluation of pharmacy services.

    • Individualized Drug Therapy for Patients

      • 1st Edition
      • November 8, 2016
      • Roger W Jelliffe + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 3 3 4 8 7
      • eBook
        9 7 8 0 1 2 8 0 3 3 4 9 4
      Individualized Drug Therapy for Patients: Basic Foundations, Relevant Software and Clinical Applications focuses on quantitative approaches that maximize the precision with which dosage regimens of potentially toxic drugs can hit a desired therapeutic goal. This book highlights the best methods that enable individualized drug therapy and provides specific examples on how to incorporate these approaches using software that has been developed for this purpose. The book discusses where individualized therapy is currently and offers insights to the future. Edited by Roger Jelliffe, MD and Michael Neely, MD, renowned authorities in individualized drug therapy, and with chapters written by international experts, this book provides clinical pharmacologists, pharmacists, and physicians with a valuable and practical resource that takes drug therapy away from a memorized ritual to a thoughtful quantitative process aimed at optimizing therapy for each individual patient.

    • Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

      • 1st Edition
      • June 7, 2016
      • Thomas Lehner + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 1 0 5 9
      • eBook
        9 7 8 0 1 2 8 0 0 5 3 0 9
      This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders.

    • Percutaneous Surgery of the Upper Urinary Tract

      • 1st Edition
      • June 28, 2016
      • Petrisor Aurelian Geavlete
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 4 0 4 1
      • eBook
        9 7 8 0 1 2 8 0 2 6 6 3 2
      Percutaneous Surgery of the Upper Urinary Tract: Handbook of Endourology contains five focused, review-oriented volumes that are ideal for students and clinicians looking for a comprehensive review rather than a whole course. Each volume is easily accessible through eBook format. Topics covered review both the endourological diagnosis and treatment of prostate, urethral, urinary bladder, upper urinary tract, and renal pathology. All chapters describe the most recent techniques, review the latest results, and analyze the most modern technologies. In the past ten years, the field of endourology has expanded beyond the urinary tract to include all urologic minimally invasive surgical procedures. Recent advancements in robotic and laparoscopic bladder surgery make this one of the fastest moving fields in medicine. As current textbooks are too time-consuming for busy urologists or trainees who also need to learn other areas of urology, this collection provides quick references and over 4000 images that are appropriate for fellows as well as those teaching in the field.

    • The Microbiota in Gastrointestinal Pathophysiology

      • 1st Edition
      • November 16, 2016
      • Martin H. Floch + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 0 2 4 9
      • eBook
        9 7 8 0 1 2 8 0 4 0 6 2 1
      The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research.

    • Cardioskeletal Myopathies in Children and Young Adults

      • 1st Edition
      • October 22, 2016
      • John Lynn Jefferies + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 0 4 0 3
      • eBook
        9 7 8 0 1 2 8 0 0 5 8 0 4
      Cardioskeletal Myopathies in Children and Young Adults focuses on plaques that kill people in their 40’s-50’s and the way they start to form in young adulthood. The Annals of Family Medicine report that approximately half of young adults have at least one cardiovascular disease risk factor (Mar 2010), and an increase in cardiovascular mortality rates in young adults was substantiated in a study at Northwestern Medicine (Nov 2011). Given the increasing recognition of genetic triggers behind all types of cardiovascular disease, and the growing population of young adults with primary or acquired myocardial disease, the need has arisen for a reference that offers a comprehensive approach to the understanding of basic, translational, and clinical aspects of specific muscle diseases while making the link between young adult and adult health.

    • Fundamental Statistical Principles for the Neurobiologist

      • 1st Edition
      • February 11, 2016
      • Stephen W. Scheff
      • English
      • Paperback
        9 7 8 0 1 2 8 0 4 7 5 3 8
      • eBook
        9 7 8 0 1 2 8 0 5 0 5 1 4
      Fundamental Statistical Principles for Neurobiologists introduces readers to basic experimental design and statistical thinking in a comprehensive, relevant manner. This book is an introductory statistics book that covers fundamental principles written by a neuroscientist who understands the plight of the neuroscience graduate student and the senior investigator. It summarizes the fundamental concepts associated with statistical analysis that are useful for the neuroscientist, and provides understanding of a particular test in language that is more understandable to this specific audience, with the overall purpose of explaining which statistical technique should be used in which situation. Different types of data are discussed such as how to formulate a research hypothesis, the primary types of statistical errors and statistical power, followed by how to actually graph data and what kinds of mistakes to avoid. Chapters discuss variance, standard deviation, standard error, mean, confidence intervals, correlation, regression, parametric vs. nonparametric statistical tests, ANOVA, and post hoc analyses. Finally, there is a discussion on how to deal with data points that appear to be "outliers" and what to do when there is missing data, an issue that has not sufficiently been covered in literature.

    • Electrophysiology and Microinjection

      • 1st Edition
      • Volume 4
      • July 2, 2016
      • P. Michael Conn
      • English
      • eBook
        9 7 8 1 4 8 3 2 8 4 8 9 7
      Electrical activity is central to the functioning and nature of neural cells. Every effort has been made in this volume to provide representative examples of useful techniques that have made this area a productive component of the neurosciences.

    • Abstracts

      • 1st Edition
      • April 19, 2016
      • J. R. Boissier + 2 more
      • English
      • eBook
        9 7 8 1 4 8 3 1 5 7 2 5 2
      Abstracts contains the abstracts of work presented at the 7th International Congress of Pharmacology: invited lectures, symposia, methodological seminars, and free communications. The abstracts are organized in chronological order of presentation at the Congress. Some abstracts focus on chemistry and biochemistry of pituitary endorphins and their precursors; the biosynthesis and release of the enkephalins; enkephalin dynamics and neuronal localization; and physiological and pathophysiological relevance of the opiate receptors and their endogenous ligands. Other papers center on the mechanism of muscarinic receptor action; regulation of cholinergic receptor metabolism in skeletal muscle; the role of vitamin E in ozone-induced pulmonary toxicity; alcohol and electrophysiology of the central nervous system; and pharmacokinetic aspects of drug-alcohol interaction.

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