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Books in Life sciences

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    • The Liver

      • 1st Edition
      • October 27, 2016
      • Kasper Blond + 1 more
      • English
      • Hardback
        9 7 8 1 4 8 3 2 2 8 5 3 2
      • Paperback
        9 7 8 1 4 8 3 2 5 1 7 8 3
      • eBook
        9 7 8 1 4 8 3 2 8 1 0 6 3
      The Liver: Porta Malorum (The Gateway to Disease) presents the fundamental aspects and significance of liver as a detoxicating organ. This book explains the diversity of the signs produced by liver damage. Organized into 17 chapters, this book begins with an overview of the process of assimilation through the activities of the liver cells. This text then discusses the emptying mechanisms of the gall-bladder. Other chapters consider the various diseases, including jaundice, pancreatitis, Bright's disease, bronchial asthma, toxic goiter, hemorrhoids, spontaneous thrombosis in the rectal veins, and varicose veins of the leg. This book discusses as well the generally accepted theory concerning the etiology of appendicitis, with emphasis on bacterial inflammation. The final chapter deals with rectal varicose disorders. This book is a valuable resource for hepatologists, pathologists, morphologists, and physicians. Medical students and research workers interested in the fundamental aspects of the liver will also find this book extremely useful.

    • Chromatin Regulation and Dynamics

      • 1st Edition
      • October 25, 2016
      • Anita Göndör
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 3 9 5 1
      • eBook
        9 7 8 0 1 2 8 0 3 4 0 2 6
      Chromatin Regulation and Dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The final chapters discuss the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin Regulation and Dynamics, part of the Translational Epigenetics series, facilitates the flow of information between research areas such as chromatin regulation, developmental biology, and epidemiology by focusing on recent findings of the fast-moving field of chromatin regulation.

    • Neuropathology of Drug Addictions and Substance Misuse Volume 1

      • 1st Edition
      • March 7, 2016
      • Victor R Preedy
      • English
      • Hardback
        9 7 8 0 1 2 8 0 0 2 1 3 1
      • eBook
        9 7 8 0 1 2 8 0 0 3 7 6 3
      Neuropathology of Drug Addictions and Substance Misuse, Volume One: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids, Opioids and Emerging Addictions provides the latest research in an area that shows that the neuropathological features of one addiction are often applicable to those of others. The book also details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment. The three volumes in this series address new research and challenges, offering comprehensive coverage on the adverse consequences of the most common drugs of abuse, with each volume serving to update the reader’s knowledge on the broader field of addiction, while also deepening our understanding of specific addictive substances. Volume One addresses tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functiona... neurological aspects of a given substance, along with a focus on the adverse consequences of addictions.

    • Septins

      • 1st Edition
      • Volume 136
      • July 25, 2016
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 9 9 8 4
      • eBook
        9 7 8 0 1 2 8 0 4 0 2 9 4
      Septins provides established septin and molecular and developmental biologists and researchers new to the field with proven, state-of-art techniques and relevant historical background and theory to aid efficient design and effective implementation of experimental methodologies. Topics include the purification of septin proteins from diverse systems, their visualization in live cells, and their analysis by a variety of cutting-edge microscopy approaches.

    • Innovative Approaches in Drug Discovery

      • 1st Edition
      • October 3, 2016
      • Bhushan Patwardhan + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 1 8 1 4 9
      • eBook
        9 7 8 0 1 2 8 0 1 8 2 2 4
      Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevan... tools and technologies, the need is great and the time is now for a renewed commitment towards expanding the repertoire of medicines. By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences.

    • The Pituitary

      • 4th Edition
      • December 29, 2016
      • Shlomo Melmed
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 1 6 9 7
      • eBook
        9 7 8 0 1 2 8 1 3 4 2 1 4
      The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland. The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine.

    • Agrarian Development in Peasant Economies

      • 1st Edition
      • June 6, 2016
      • Eric Clayton
      • M. Mcg. Cooper
      • English
      • Paperback
        9 7 8 0 0 8 0 1 0 5 6 1 1
      • eBook
        9 7 8 1 4 8 3 1 3 8 0 0 8
      Agrarian Development in Peasant Economies: Some Lessons from Kenya examines agrarian development in peasant, agricultural economies by focusing on Kenya and the lessons that can be learned from its experience. Topics covered include the beginnings of rural progress in Kenya; post-war agricultural policies and developments; the agrarian revolution; and the economics of peasant agriculture. Problems associated with agrarian reform are also discussed. This volume is comprised of seven chapters and begins with a historical background on Kenya's peasant agriculture, paying particular attention to the government's initiatives aimed at increasing agricultural production and controlling soil erosion. The next chapter deals with the country's agricultural policies after World War II, including the implementation of a ten-year development plan and introduction of incentives to improve farming. Subsequent chapters look at the agrarian revolution in Kenya; certain features of peasant agriculture, including indigenous farming systems; the economics of the farm and the agricultural sector; and the policies pursued by the government to achieve agrarian development. The final chapter considers some of the issues affecting agrarian reform, including smallholding and rights of ownership and financing of rural development, in part by taxation. This monograph will be of interest to farmers and agriculturists as well as agricultural and economic policymakers.

    • Genome Stability

      • 1st Edition
      • September 3, 2016
      • Igor Kovalchuk + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 3 0 9 8
      • eBook
        9 7 8 0 1 2 8 0 3 3 4 5 6
      Every species has to preserve the integrity of its genome to ensure faithful passage of genetic information to the progeny. At the same time, there are times during the life of the organism and population in general when a fine balance in genome stability and diversification has to be made to benefit the survival of the species. Genome Stability teaches the reader how various species maintain this fine balance in genome stability and genome diversification in response to their environments. Genome Stability covers a wide range of topics, including the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes and mammals. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability as well as changes in genome stability in response to aging. Finally, Genome Stability covers how epigenetic factors contribute to genome stability and how the species pass the memory of the encounters to the progeny, thus influencing the genome of the progeny in an indirect manner. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly-expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability.

    • Advances in Genetics

      • 1st Edition
      • Volume 93
      • February 23, 2016
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 8 0 1 6
      • eBook
        9 7 8 0 1 2 8 0 5 2 1 7 4
      Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

    • Pediatric Brain Tumors Update, An Issue of Neuroimaging Clinics of North America

      • 1st Edition
      • Volume 27-1
      • November 29, 2016
      • Lara A. Brandão
      • English
      • Hardback
        9 7 8 0 3 2 3 4 9 6 5 4 4
      • eBook
        9 7 8 0 3 2 3 4 9 6 6 4 3
      This issue of Neuroimaging Clinics of North America focuses on Pediatric Brain Tumors, and is edited by Dr. Lara A. Brandão. Articles will include: Posterior fossa tumors in pediatric patients; Supratentorial tumors in pediatric patients; Brain tumors in the neonate; Pineal region masses in pediatric patients; Sellar and suprasellar tumors in pediatric patients; Extraparenchymal lesions in pediatric patients; Tumor and tumor-like masses in pediatric patients that involve multiple spaces; Neuroimaging of innovative peptide base vaccine therapy in pediatric brain tumors; Advanced MRI in pediatric brain tumors: clinical applications; and much more!

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