Molecular Medicine and Biomedical Research in the Era of Precision Medicine: New Technologies and Personalized Drug Therapies for Patient Care provides researchers with an extensive overview of recent advances in molecular biology impacting the development of targeted therapies. The book delivers insights into the pathobiological and pathogenetic mechanisms of various diseases, providing a detailed study of the latest personalized interventions to be implemented across such conditions. It covers a range of technologies, including RNA-sequencing, AI, Machine Learning, gene therapy, omics and nanotechnology, delving into their clinical applications across various diseases.The book also tackles targeted treatments of different disease types, including acute, chronic, infectious and noncommunicable diseases. Future perspectives are also covered, providing an in-depth study across molecular medicine, drug discovery and delivery, disease diagnosis and prevention, and therapeutic interventions, and acting as an invaluable interdisciplinary reference for researchers across the biomedical sciences.
Innovations in Cardio-Oncology: Artificial Intelligence, Digital Health, and Precision Medicine examines the benefits of big data analysis and future advancements in individualized medicine in cardio-oncology. The book helps readers understand and maximize the benefits of existing AI algorithms by integrating AI and digital health technologies into the clinical workflow, exploring AI orchestration, testing of AI applications, processing steps, active involvement and collaboration of qualified employees, and many other factors. The book introduces cardio-oncology and describes the prevention, screening and surveillance in cardio-oncology, followed by several chapters on the emerging role of the applications of mHealth, telemedicine and Artificial intelligence in cardio-oncology.The book also highlights many societal and evidence-based recommended pathways for equitable digital health deployment and utilization in cardio-oncology care. It anticipates that exposing the potential for AI algorithms and innovative health tools widens the already existing healthcare disparities, including inequalities related to race, ethnicity, gender, socioeconomic level, lack of health insurance, linguistic and cultural barriers, systemic discrimination, and limited healthcare access.
Pharmacology, Physiology, and Practice of Obstetric Anesthesia provides all the essentials of obstetric anesthesia in a straightforward, user-friendly format that avoids encyclopedic language and lengthy discussions, and is inclusive of other healthcare specialties and sub-specialties including obstetrics, neonatal care, and more. Coverage spans the essentials of obstetric as well as overlooked issues including obstetric pharmacology and physiology safe practice strategies, clinical concepts for vaginal delivery and c-section, high-risk pregnancy states and management of the complicated parturient, complications and medicolegal, fetus and newborn considerations, and guidelines, standards and statements related to obstetric anesthesia.Pharmacology, Physiology, and Practice of Obstetric Anesthesia is the perfect reference for an interdisciplinary group of health professionals, policymakers, and researchers working and training in the field of obstetric anesthesiology.
Veterinary Toxicology: Basic and Clinical Principles, Fourth Edition is a unique single reference that provides a comprehensive overview on the basic principles of veterinary toxicology to any student at the DVM, MS, or PhD level while also continuing to serve as a clinical reference for practitioners. The book thoroughly updates toxicologists and advanced students on the newest approaches for diagnosing poisoning cases in all animals from chemicals, plants, and accidental or malicious intents. Many chapters are provided on topics not covered in any previous books, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology.Completely revised and updated to include the most recent developments in the field animal toxins, toxicokinetics mechanism of action, toxicity, and treatment, this book is an essential resource for researchers, practicing veterinary toxicologists, advanced students in toxicology, poison control centers, as well as environmentalists, marine biologists, and animal scientists.
Bioinformatics and Computational Biology (BCB) combine elements of computer science, information technology, mathematics, statistics, and biotechnology, providing the methodology and in silico solutions to mine biological data and processes, for knowledge discovery.In the era of molecular diagnostics, targeted drug design, translational medicine and Big Data for personalized medicine, computational methods for data analysis are essential tools for biochemistry, biology, biotechnology, pharmacology, biomedical and computer science, as well as mathematics and statistics. New areas are emerging, and relatively isolated fields are becoming current hot research areas in BCB, such as Artificial Intelligence, Quantitative Biology, Computational Vaccinology, Epidemiology and Infection Diffusion, Synthetic Biology, and Phenomics. The role of BCB in characterizing SARS-CoV-2 variants and facing the COVID-19 pandemic is just one example of how these tools can help us better prepare for such future events.This Encyclopedia comprises three sections, covering Methods, Topics, and Applications. The methodologies and algorithms underpinning BCB are described in the Methods section; Topics covers traditional areas such as phylogeny, as well as more recent areas such as translational bioinformatics, cheminformatics and environmental informatics; Applications provides guidance for commonly asked “how to” questions.Navigating the maze of confusing jargon and the plethora of software tools is often confronting for students and researchers alike. This comprehensive and unique resource provides up-to-date theory and application content to address molecular data analysis requirements, with precise definitions of terminology and lucid explanations by field experts.
Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
In an era where Artificial Intelligence (AI) is revolutionizing healthcare, Explainable AI in Healthcare Imaging for Precision Medicine addresses the critical need for transparency, trust, and accountability in AI-driven medical technologies. As AI becomes an integral part of clinical decision-making, especially in imaging and precision medicine, the question of how AI reaches its conclusions grows increasingly significant. This book explores how Explainable AI (XAI) is transforming healthcare by making AI systems more interpretable, reliable, and transparent, empowering clinicians and enhancing patient outcomes.Through a comprehensive examination of the latest research, real-world case studies, and expert insights, this book delves into the application of XAI in medical imaging, disease diagnosis, treatment planning, and personalized care. It discusses the technical methodologies behind XAI, the challenges and opportunities of its integration into healthcare, and the ethical and regulatory considerations that will shape the future of AI-assisted medical decisions.Key areas of focus include the role of XAI in improving diagnostic accuracy in fields such as radiology, pathology, and genomics and its potential to enhance collaboration between AI systems, healthcare professionals, and patients. The book also highlights practical applications of XAI in personalized medicine, showing how explainable models help tailor treatments to individual patients, and discusses how XAI can contribute to reducing bias and improving fairness in medical decision-making.Written by leading experts in AI, healthcare, and precision medicine, Explain[S3G1] able AI in Healthcare Imaging for Precision Medicine is an essential resource for researchers, clinicians, students, and policymakers. Whether you are looking to stay at the forefront of AI innovations in healthcare or seeking to understand how explainability can build trust in AI systems, this book provides the insights and knowledge needed to navigate the evolving landscape of AI in medicine. It invites readers to explore how XAI can revolutionize healthcare and precision medicine, shaping a future where AI is both powerful and trustworthy.
Human- Centric Integration of Next Generation Data Science and Blockchain Technology: Advancing Society 5.0 Paradigms focuses on the current technological landscape, addressing the evolving integration of data science and blockchain within the context of Society 5.0. This comprehensive resource explains the convergences between data science, blockchain, and the human-centric vision of Society 5.0, while also filling the gap in understanding and navigating this transformative intersection with recent shifts towards more decentralized and data-driven paradigms.The book introduces the concept of Society 5.0, examining the historical context, and outlines the evolving technological landscape shaping our interconnected future. It discusses the fundamental principles of data science, from data collection and preprocessing to exploratory data analysis and explains the transformative impact of data science and blockchain across industries such as healthcare, finance, education, and transportation. This book is essential to understanding and shaping the future of technology and society from decentralized solutions to predictive analytics/ emerging technologies.
The Immunology of Domestic Ruminants: Cattle, Sheep, and Goats provides a thorough examination of the immune systems of these animals. It explores their normal immune functions and their roles in combating infectious and parasitic diseases, chronic inflammatory conditions, and immunodeficiency disorders. The book incorporates new data from the bovine genome project and highlights significant breed differences. Both innate and adaptive immunity are systematically covered, offering insights into basic and applied aspects of bovine immunology. In addition to detailing the immunology of major bacterial, viral, and parasitic diseases in cattle, the book reviews bovine vaccines and emphasizes the importance nutrition.This essential resource caters to professionals in large animal research and practice, providing comprehensive information on the immunology of domestic cattle, sheep, and goats.
Natural Biopolymers for Drug Delivery thoroughly details the properties, benefits and challenges of using these biomaterials in drug delivery, with a strong focus on biocompatibility and reduction of unwanted interactions. An extensive range of natural biopolymers are explored, such as cellulose, chitosan, casein, gelatin, cashew gum, and many more. Biocompatibility, toxicity and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science and pharmacology, chemical engineering and clinical science.