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Elsevier

Books in Life sciences

  • New Techniques for Management of ‘Inoperable’ Gliomas

    • 1st Edition
    • Michael E. Sughrue + 1 more
    • English
    New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients.

  • Cancer Immunotherapy

    • 1st Edition
    • Volume 164
    • David B. Teplow
    • English
    Cancer Immunotherapy, Volume 165 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to different approaches to cancer immunotherapy, with this release focusing on TNFR2 in cancer immunology and immunotherapy, From the Hellstrom paradox towards cancer cure, CAR T-cell treatment of T-cell malignancy , Immunotherapy of pancreatic cancer, Cancer stem cell immunology/immunothe... Cytokine release syndrome, Tumor cell-based mechanisms of resistance to immune attack, and Mushroom compounds in cancer immunotherapy.

  • Neurophysiologie

    De la physiologie à l'exploration fonctionnelle - avec simulateur informatique
    • 3rd Edition
    • Jean-François Vibert + 8 more
    • French
    Ce manuel expose les connaissances actuelles en neurophysiologie dans une optique clinique. Il présente de manière simple et claire le fonctionnement du système nerveux et les conséquences cliniques de ses dysfonctionnements.À partir de leur expérience, les auteurs, médecins enseignants-chercheu... décrivent les méthodes physiologiques d’exploration du système nerveux normal et pathologique, et les résultats que l’on peut en attendre. Le lecteur acquiert ainsi les connaissances indispensables à la prescription et à l’interprétation de tels examens. L’abondante iconographie en couleurs illustre avec justesse un texte didactique et complet.Cette 3e édition propose une révision approfondie de l’ensemble des contenus en optimisant l’aspect et l’approche pédagogique :• les parties sur les explorations fonctionnelles d’une part et celles sur les troubles et la clinique d’autre part sont désormais harmonisées et individualisées dans des encarts ;• de nouvelles illustrations viennent enrichir l’iconographie ;• par ailleurs, le lecteur bénéficie d’un accès en ligne à toute l’iconographie de l’ouvrage (260 illustrations), grâce à une banque d’images ;• de nombreux exercices pratiques à réaliser à l’aide d’un simulateur informatique, sont également accessibles en ligne, afin d’appréhender aisément le fonctionnement des neurones et le comportement des réseaux de neurones.Neurophysio... est destiné aux étudiants en médecine, en sciences paramédicales et STAPS. Sa lecture constituera également une aide pour les médecins et les autres professionnels de santé.

  • Neuropsychotherapeutics

    • 1st Edition
    • Volume 86
    • English
    Neuropsychotherapeut... Volume 86, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field, with this updated edition including sections on Pharmacotherapy of psychiatric disorders, Allosteric mechanisms for neuropsychopharmacol... Lipid rafts, Rapid-acting antidepressants, mGlu2/3 receptor antagonists, Nitric oxide: antidepressant mechanisms and inflammation, Anxiety disorders, mGlu receptors and schizophrenia, mAChR ligands for schizophrenia and addiction, PDE10 inhibitors, Obsessive-compulsive disorder, Addiction disorders (including eating), Dopamine D1 PAMs as a New Mode for Treatment of Neuropsychiatric Disorders, and more.

  • Opioid Hormones

    • 1st Edition
    • Volume 111
    • Gerald Litwack
    • English
    Vassopressin, Volume 111, the latest release in the Vitamins and Hormones series, first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

  • Freshwater Microbiology

    Perspectives of Bacterial Dynamics in Lake Ecosystems
    • 1st Edition
    • Suhaib A. Bandh
    • English
    Freshwater Microbiology: Perspectives of Bacterial Dynamics in Lake Ecosystems provides a comprehensive and systematic analysis of microbial ecology in lakes. It offers basic information on how well the bacterial community composition varies along the spatio-temporal and trophic gradients along with the evaluation of the bioindicator species of bacteria so as to act as a key to predict the trophic status of lake ecosystems. The book helps to identify the factors of potential importance in structuring the bacterial communities in lakes as it delves into the dynamics and diversity of bacterial community composition in relation to various water quality parameters. It helps to identify the possibility of bioremediation plans and devising future policy decisions, with better conservation and management practices.

  • Classification Techniques for Medical Image Analysis and Computer Aided Diagnosis

    • 1st Edition
    • Nilanjan Dey
    • English
    Classification Techniques for Medical Image Analysis and Computer Aided Diagnosis covers the most current advances on how to apply classification techniques to a wide variety of clinical applications that are appropriate for researchers and biomedical engineers in the areas of machine learning, deep learning, data analysis, data management and computer-aided diagnosis (CAD) systems design. The book covers several complex image classification problems using pattern recognition methods, including Artificial Neural Networks (ANN), Support Vector Machines (SVM), Bayesian Networks (BN) and deep learning. Further, numerous data mining techniques are discussed, as they have proven to be good classifiers for medical images.

  • Ecophysiology of Pesticides

    Interface between Pesticide Chemistry and Plant Physiology
    • 1st Edition
    • Talat Parween + 1 more
    • English
    Ecophysiology of Pesticides: Interface between Pesticide Chemistry and Plant Physiology is the first comprehensive overview of the physical impact of this increasingly complex environmental challenge. Designed to offer state-of-the-art knowledge, the book covers pesticide usage and its consequences on the ecophysiology of plants. It includes the challenge of policymaking in pesticide consumption and a risk analysis of conventional and modern approaches on standard usage. In addition, it summarizes research reports pertaining to the physio-ecological effects of pesticides, discusses the environmental risks associated with the over-utilization of pesticides, and covers pesticide usage on the micro-flora and rhizosphere. This book is a valuable reference for plant ecologists, plant biochemists and chemists who want to study pesticide consumption and its biochemical and physiological evaluation effects on plants. It will also be of immense help to university and college teachers and students of environmental biotechnology, environmental botany and plant ecophysiology.

  • Single-Cell Omics

    Volume 2: Technological Advances and Applications
    • 1st Edition
    • Debmalya Barh + 1 more
    • English
    Single-cell Omics, Volume 2: Advances in Applications provides the latest single-cell omics applications in the field of biomedicine. The advent of omics technologies have enabled us to identify the differences between cell types and subpopulations at the level of the genome, proteome, transcriptome, epigenome, and in several other fields of omics. The book is divided into two sections: the first is dedicated to biomedical applications, such as cell diagnostics, non-invasive prenatal testing (NIPT), circulating tumor cells, breast cancer, gliomas, nervous systems and autoimmune disorders, and more. The second focuses on cell omics in plants, discussing micro algal and single cell omics, and more. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and several members of biomedical field interested in understanding more about single-cell omics and its potential for research and diagnosis.

  • Cellular and Animal Models in Human Genomics Research

    • 1st Edition
    • English
    Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth.

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