Serotonin
The Mediator that Spans Evolution
- 1st Edition - September 21, 2018
- Latest edition
- Editor: Paul M. Pilowsky
- Language: English
Serotonin: The Mediator That Spans Evolution provides a comprehensive review of the widespread roles for serotonin in respiratory, cardiovascular and thermoregulatory control,… Read more
End of Summer Sale
Save up to 30% off
Bright savings for research, study, and discovery
Description
Description
Serotonin: The Mediator That Spans Evolution provides a comprehensive review of the widespread roles for serotonin in respiratory, cardiovascular and thermoregulatory control, and for growth and development in early life. This important resource highlights serotonin’s role in normal (unstressed) conditions, and in response to a variety of physiological stressors. It focuses on new animal models, comparing and contrasting data from mice and rats. In addition, the book compares and contrasts the physiological effects of brain and blood serotonin systems and includes new data suggesting that the influence of serotonin is in part through the regulation of gene expression.
Finally, it discusses the role of serotonin system dysfunction in a variety of pathophysiological conditions, including sleep apnea, obesity and hypertension, and presents compelling evidence that this dysfunction is involved in Sudden Infant Death Syndrome (SIDS).
Key features
Key features
- Includes the latest information on new animal models of serotonin system dysfunction
- Explores the wide scope of serotonin’s influence on multiple organ and physiological systems
- Highlights the autonomous functioning of the brain and body serotonin systems
- Provides compelling evidence of serotonin dysfunction in SIDS, a leading cause of death in infancy
Readership
Readership
Basic and clinical researchers of systems physiology as well as clinicians
Table of contents
Table of contents
BIOPHYSICS OF SEROTONIN
1. Biophysics of Serotonin and the Serotonin1A Receptor: Fluorescence and Dynamics
Amitabha Chattopadhyay
2. Serotonin in plants: origin, function, and implications
Praveen Saxena
ANATOMY
3. The anatomy of the serotonin system in different model systems: rat fish, flies and C. Elegans
Patricia Gaspar and Christina Lillesaar
4. Serotonin in the endocrine pancreas
Malin Fex
5. Serotonin and platelets
Simone Marianne Schoenwaelder
6. Anatomy of the Serotonin Transporter
Arnauld Belmer, Kate Beecher and Selena E. Bartlett
PHYSIOLOGY IN THE PERIPHERY
7. Cellular regulation of peripheral serotonin
Damien Keating
8. Role of 5-HT in the control of gut motility
Nicholas John Spencer
9. Phenotype of animals deficient in peripheral serotonin
Michael Bader
10. Serotonin and immune system
Luc Maroteaux and Anne Roumier
11. Serotonin and Adipocyte Function
Malin Fex and Karin Stenkula
12. Serotonin and cardiovascular diseases
Luc Maroteaux and Laurent Monassier
13. Involvement of 5-HT in afferent modulation of brainstem circuits regulating cardiovascular homeostasis
Andrew Ramage and Patrick Hosford
14. Regulation of nociceptor signalling by serotonin
Stefan Boehm and Isabella Salzer
PHYSIOLOGY IN THE BRAIN
15. Brain serotonin and energy homeostasis
Yong Xu
16. Serotonin in central cardiovascular control
Paul M. Pilowsky
17. Serotonin receptors and cardiovascular control
Caroline Sevoz-Couche
18. Serotonin receptors as the therapeutic target for central nervous system disorders
Yukihiro Ohno
19. Serotonin and the reconfiguration of the eupneic respiratory pattern
Daniel Zoccal
20. Life without brain serotonin: phenotype of animals deficient in central serotonin synthesis
Valentina Mosienko and Natalia Alenina
Product details
Product details
- Edition: 1
- Latest edition
- Published: September 21, 2018
- Language: English
About the editor
About the editor
PP
Paul M. Pilowsky
Paul M. Pilowsky is Professor Emeritus at the University of Sydney. He trained in medicine, physiology and neuroscience. He specialises in the role of molecular mediators in the regulation of airways, breathing and the circulation by neurons in the brainstem and spinal cord.He previously held tenured Professor positions at the University of Sydney and Macquarie University, where he also established the research and graduate medical school, served on multiple major University and Faculty committees, and supervised many graduate students.
Professor Pilowsky has won multiple award, including the Australasian Neuroscience Society Medal. He has published extensively in his field, including original articles, books and book chapters. He has published two books with Elsevier, Serotonin: The Mediator That Spans Evolution and Angiotensin: From the Kidney to Coronavirus. He is editor for the Elsevier book series Molecular Mediators in Health and Disease: How Cells Communicate.