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Elsevier

Books in Life sciences

  • Nanotherapeutics for Treating Neurodegenerative Disorders

    • 1st Edition
    • Manish K. Chourasia + 3 more
    • English
    Nanotherapeutics for Treating Neurodegenerative Disorders is a comprehensive guide to the cutting edge field of nanotherapeutics. This book reviews the complex landscape of neurodegenerative disorders, outlining the nuances of treatment strategies and the imperative role of nanotechnology in revolutionizing therapeutic interventions. From explaining the transport mechanisms of the blood–brain barrier to unveiling the therapeutic potential of stem cell-derived nanocarriers, each chapter offers invaluable insights into the diverse array of nanotherapeutic approaches, helping to reshape the landscape of neurological healthcare. This book provides a comprehensive resource for clinicians, researchers, and students in the fields of neurology and nanotherapeutics.

  • The Exposome in Cancer Disparities

    Influence of Environmental and Infectious Factors in LMICs
    • 1st Edition
    • Zodwa Dlamini
    • English
    The Exposome in Cancer Disparities: Influence of Environmental and Infectious Factors in LMICs examines how environmental and infectious factors drive cancer inequities in low- and middle-income countries (LMICs). The book introduces the exposome as a comprehensive framework to understand complex risk factors, such as environmental toxins, climate change, and infectious agents like HPV and HIV. The book combines scientific insights, real-world case studies, and practical strategies from international experts, highlighting region-specific contributors to cancer disparities. Structured into thematic sections, it offers a holistic view of the challenges faced by LMICs and provides actionable, evidence-based solutions tailored to resource-limited settings.The work emphasizes the importance of multidisciplinary approaches and international collaboration to develop effective prevention and policy strategies. It will benefit researchers, policymakers, and healthcare professionals by deepening understanding of cancer risk factors, fostering global cooperation and guiding targeted interventions to reduce health inequities and improve outcomes worldwide.

  • ​​Cannabinoids for Chronic Pain

    From Research to Clinical Applications​
    • 1st Edition
    • Alaa Abd-Elsayed
    • English
    Cannabinoids for Chronic Pain: From Research to Clinical Applications provides an in-depth exploration of cannabinoids and their applications in modern medicine. The book begins with an historical overview, followed by a detailed examination of the endocannabinoid system and cannabinoid receptors. Next, sections cover various phytocannabinoids, including CBD and THC, as well as synthetic cannabinoids like dronabinol and nabilone. Each chapter delves into the pharmacokinetics, pharmacodynamics, actions, and side effects. The content is meticulously organized to address the medical uses of cannabinoids, including in pain management, perioperative care, and their applications in specific populations such as children, pregnant women, and the elderly.Sections also discuss the medicolegal considerations surrounding cannabinoid use. Contributions from leading experts provide evidence-based recommendations and practical guidelines for clinical practice, ensuring a comprehensive understanding of the subject. This book is an invaluable resource for healthcare professionals, researchers, and students. It bridges the gap between research and clinical practice, offering practical insights and up-to-date information. Readers will benefit from its thorough coverage, multidisciplinary perspectives, and detailed discussions, making it an essential guide for anyone involved in the medical use of cannabinoids.

  • Mucins

    • 1st Edition
    • Volume 732
    • English
    Mucins, Volume 732 serves as a valuable resource for researchers aiming to investigate mucin biology in greater depth, offering a wide range of experimental approaches and analytical strategies. Topics in this new release cover Enrichment/isolation... glycoproteomics, Mucinase cleavage characterization and usage in glycoproteomics, Fluorescent protein-based FRET substrates for activity screening of mucinases, Development of clinical lectin assays based on MS glycomic discovery, Enzymatic selective sulfation of synthetic mucins, cryoEM, Cell-based mucin arrays and glycoengineering, CRISPR screens to characterize and identify glycan-binding proteins, and much more.Additional sections cover MD Simulations, Interactions with pathogenic bacteria, Interactions with microbiota, Covalent crosslinking of mucins, Liquid Glycan and Liquid Lectin Array-based exploration of musin recognition, Quantification of mucins, Mucins in IBD, Investigations of mucins and innate immunity, Generating synthetic mucin glycopeptides, and Microscopy and imaging.

  • MRI of Brain Physiology

    Novel Methods and Clinical Applications
    • 1st Edition
    • Audrey P. Fan + 1 more
    • English
    MRI of Brain Physiology: Novel MRI Methods and Clinical Applications delves into the intricate world of brain physiology, focusing on the latest magnetic resonance imaging (MRI) methods and their clinical applications. Designed for biomedical engineers, technologists, radiologists, neurologists, neurosurgeons, and clinical researchers, this resource bridges the gap between advanced imaging techniques and practical clinical use. It covers a wide spectrum of cerebral physiology, from microvascular and macrovascular dynamics to cerebrovascular reserve, neurovascular coupling, and cerebrospinal fluid pathways. Each of the core chapters has a tripartite structure: physiology (concepts of the physiological processes), imaging techniques, and clinical applications. Readers will find detailed discussions on emerging MRI methods, including dynamic contrast, arterial spin labeling, and quantitative BOLD models. The book also addresses the functional impact of physiological changes on tissue microstructure and integrity, offering insights into multiparametric relaxation mapping and quantitative susceptibility mapping. Uniquely, this book gives a comparative approach to different brain physiological MRI methods, highlighting their strengths, limitations, and reliability.

  • Agroforestry Solutions for Soil Restoration and Sustainable Land Management

    • 1st Edition
    • Ram Prakesh Yadav + 3 more
    • English
    Agroforestry Solutions for Soil Restoration and Sustainable Land Management, a volume in the Agricultural Soil Degradation and Restoration series, offers a rigorous, cross-disciplinary assessment of tree–crop integration as a driver of resilient landscapes and livelihoods around the world. Rooted in edaphic science, agroecology, and development studies, it analyzes contemporary pressures, evaluates viable interventions, and maps forward-looking research avenues. By blending empirical evidence with policy considerations, it demonstrates how diversified, multi-species systems enhance nutrient balance, water regulation, carbon dynamics, and biodiversity, while supporting stable incomes and high-quality food.This essential resource for researchers, educators, and practitioners covers design principles, deployment pathways, governance, extension strategies, and economic analysis, complemented by real-world case studies. Readers will find robust study designs, interoperable data assets, and reproducible workflows that enable scalable decision-making and monitoring. The narrative emphasizes UNCCD targets and climate-smart land use, with clear implications for sustainable intensification and ecosystem stewardship.

  • An Illustrated Guide to Cancer Biology

    • 1st Edition
    • Tomas Koltai + 1 more
    • English
    An Illustrated Guide to Cancer Biology offers a comprehensive exploration of the fundamentals of oncological molecular biology and provides valuable insights into topics such as cancer cell migration, chemotherapeutic drug mechanisms, and the roles of RNA in cancer. With 33 chapters covering a wide array of subjects, including the Hanahan and Weinberg hallmarks of cancer, tumor heterogeneity, and hormone-dependent cancer, this guide serves as an indispensable resource for researchers, students, and practicing oncologists in medicine, oncology, and biochemistry alike. This book stands out not only for its comprehensive coverage of diverse topics but also for its unique approach.With over 400 figures strategically interspersed throughout the text, this book offers readers a visually engaging journey through the intricacies of cancer biology. These illustrations, ranging from molecular pathways to cellular interactions, make navigating topics like chemotherapeutic drug mechanisms and tumor heterogeneity more accessible. Additionally, the inclusion of sections on repurposing drugs, tumor kinetics, and epigenetics further aids in a deep understanding of cancer biology.

  • Moving Toward Nonanimal Approaches in Medical Research and Testing

    • 1st Edition
    • Gail A. Van Norman + 1 more
    • English
    Moving Toward Nonanimal Approaches in Medical Research and Testing pioneers a single-source guide for researchers regarding nonanimal research tools and methodologies and their many advantages and applications in place of animals. This book is presented in three parts: historical, ethical, legislative, and scientific contexts on the need to shift away from animal-based research and testing; the latest advances in nonanimal tools and methods for biomedical research and testing of human therapeutics and other compounds, including microphysiological systems, bioprinting, biobanks, and artificial intelligence; and achieving a practical shift toward these powerful approaches, including advocacy for legal, regulatory, and policy change, securing funding for nonanimal studies, and how to overcome bias against nonanimal methods. This book, primarily directed to researchers in biomedicine, human medical therapeutics, and toxicology, will also appeal to researchers in industry, providing overview and insights about the latest applications of nonanimal research tools and methods for product development and testing. Clinicians who wish to understand the reliability of testing therapeutics with nonanimal versus animal methods, as well as advocacy groups seeking an up-to-date understanding of ethical, economic, political, and scientific considerations in moving toward nonanimal approaches, will also find significant value in this text. Finally, legislators and those involved in regulatory review and oversight will benefit from this single comprehensive source for developing a basic understanding of nonanimal research and human safety.

  • Cardiometabolic Dynamics

    A Deep Dive into Health and Disease
    • 1st Edition
    • Yihua Bei + 1 more
    • English
    Cardiometabolic Dynamics: A Deep Dive into Health and Disease explores the intricate relationship between metabolic health and cardiovascular diseases, illuminating how cellular and molecular mechanisms contribute to metabolic dysregulation. The book delves into the ways metabolic pathologies act as precursors to cardiovascular conditions, including hypertension, atherosclerosis, cardiomyopathy, and heart failure. With a focus on healthy cardiometabolic dynamics, it underscores the crucial role they play in sustaining cardiovascular wellness, offering a comprehensive perspective on the intersection of metabolism and heart health.The book further examines the influence of lifestyle factors, such as diet and exercise on cardiovascular metabolism and highlights emerging technologies like omics, genetic engineering, and wearable devices to advance research, diagnosis, and treatment.

  • Thin Film Photovoltaics

    Single-Junction and Tandem
    • 1st Edition
    • Jeyakumar Ramanujam + 1 more
    • English
    Thin Film Photovoltaics: Single-junction and Tandem provides a comprehensive introduction to thin film solar cells and the latest developments in this expanding field. The book includes detailed information on material properties required for solar cells, working principles, energy band structure, charge transport to the electrodes and approaches to improve efficiency. Front-end and back-end processes are discussed in detail. Current challenges to commercial translation and potential opportunities to overcome to those challenges are also covered, and factors limiting solar cells parameters are also considered. Emphasis is on new materials and state-of-the-art technologies used for fabrication and characterization.Thi... book is suitable for researchers in academia and R&D in the subject areas of materials science and engineering, energy, physics, and chemistry.

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