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Books in Life sciences

  • Robotic Platforms for Minimally Invasive Surgery

    • 1st Edition
    • Juan Sánchez-Margallo + 1 more
    • English
    Robotic Platforms for Minimally Invasive Surgery introduces the scientific community to the most popular robotic platforms for minimally invasive surgery in a more exhaustive way, allowing the readers to learn both the technical features as well as functional aspects of these platforms. This book also discusses viability, safety and efficacy of these platforms in surgical application, and is focused on users who are starting in the field of robotic surgery, both in the disciplines of laparoscopic and endoscopic surgery, as well as in microsurgery.An overview of the most widespread robotic platforms for minimally invasive surgery.

  • Episodes in the History of Medical Science

    Discovery Meets Orthodoxy
    • 1st Edition
    • Anthony R. Rees
    • English
    Episodes in the History of Medical Science: Discovery Confronts Orthodoxy highlights key moments in history where scientific and medical advances faced acceptance and rejection by the prevailing orthodoxy. This book places present-day disease protection in context by exploring significant medical and scientific theories, their success stories, challenges, and the frequent resistance to new ideas. It shows how acceptance of scientific discoveries often lags due to conservatism within the scientific community and broader socio-political and cultural influences. The book examines the origins of medical theory and practice, from the revolutionary ideas of Hippocrates and Galen to the rise of Islamic Medicine and the scholasticism of the Middle Ages. It covers the arrival of syphilis in Europe and the ensuing medical debates, the historical battle against smallpox through variolation and vaccination, and the skepticism faced by groundbreaking discoveries in the 19th and 20th centuries. Key topics include the gene debate, the thalidomide tragedy, the antibody revolution, and the paradigm shift in understanding stomach ulcers. The narrative also addresses the modern era's anti-vaccinationism and vaccine hesitancy, emphasizing the ongoing tension between scientific integrity and public acceptance. Episodes in the History of Medical Science: Discovery Confronts Orthodoxy is a valuable resource for medical professionals, researchers, historians, and students. It underscores the importance of scientific and medical integrity, the pursuit of truth, and validated scientific communication. By providing historical insights and examples of perseverance in the face of skepticism, this book offers valuable lessons for improving public health and understanding the dynamic journey of medical science.

  • Biostatistical Methods and Applications

    Experiment Design, Analysis, and Presenting Findings
    • 1st Edition
    • Jitendra Kumar Chaudhary
    • English
    Biostatistical Methods and Applications: Experiment Design, Analysis, and Presenting Findings provides students and researchers with the skills needed to apply biostatistical concepts and implement a wide range of analytical tools. The text is an accessible and intentionally curated resource that instructs readers in designing experiments, considering the results, and presenting statistical findings and views. In twenty-four chapters and additional appendices, the book starts with an introduction to the field of statistics and from there covers experiment design, data coding, and data collection methods. The book also delves into descriptive statistics, probability, statistical distributions, correlations, and regression. Common research techniques such as normality tests, sample size determination, missing data analysis, statistical inference, test of significance, and ANOVA are explained in a clear manner so that readers can successfully understand and apply these methods. Biostatistical Methods and Applications: Experiment Design, Analysis, and Presenting Findings thoroughly explores fundamental topics in biostatistics to guide readers in conducting statistical analysis and interpretation by using the step-by-step procedures and diagrams in the book. This book covers current topics which are being used frequently in teaching and research areas, as well as specific statistical techniques including multivariate analysis, binary logistic regression, and non-parametric methods. This valuable first edition provides the necessary tools and conceptual foundations in quantitative reasoning to efficiently extract information from a vast sea of data, and to communicate research findings in order to support hypotheses and give credibility to research methodology and conclusions. With detailed explanations, illustrative examples and diagrams, and beneficial in-text exercises and solutions to support the study of biostatistics, this textbook will prove useful to students, researchers, and scientists who aim to increase their precision around methods and techniques in this field.

  • Encyclopedia of Endocrine Diseases

    • 3rd Edition
    • Ilpo Huhtaniemi
    • English
    The Encyclopedia of Endocrine Diseases, Third Edition, Five Volume Set is an essential one-stop reference exploring physiological, clinical diagnostic and therapeutic aspects of a wide range of endocrine and endocrine-related metabolic diseases. This edition incorporates ground-breaking research that has occurred in the last 8 years particularly in molecular mechanisms such as mutations, epigenetics and signaling, environmental effects on homeostasis, and the pathogenesis of common endocrine diseases including endocrine malignancies, obesity, and diabetes.Among the most complex constructs in the body, the endocrine system sends chemical signals to specific receptors in other parts of the body, eliciting intracellular signaling pathways as their biological effect. The endocrine system regulates numerous processes including metabolism, biological cycles, internal fluid volume, reproduction and growth to maintain body homeostasis. However, the ways in which endocrine functioning can go awry are numerous. Providing over 420 updated articles, this 5 volume edition of Encyclopedia of Endocrine Diseases explores the extensive spectrum of metabolic and endocrine disease, capturing new diagnosis techniques, treatment methods and understanding of endocrine pathogenesis.This text, unique in its vast coverage and clear layout, is not only an indispensable resource for clinical professionals and researchers in endocrinology, but also accessible to advanced and undergraduate students.

  • Genetics of Bone Biology and Skeletal Disease

    • 3rd Edition
    • Rajesh V. Thakker + 3 more
    • English
    Genetics of Bone Biology and Skeletal Disease, Third Edition is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid, and related disorders, and vitamin D and renal disorders.Sections cover bone biology and structure, joint and cartilage biology, principles of endocrine regulation, the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasia, rarer bone disorders, and much more.

  • Translational Cardiothoracic Surgery

    • 1st Edition
    • Adam E.M. Eltorai
    • English
    Translational research is essential to the advancement of medicine. This Cardiothoracic-speci... instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in cardiothoracic surgery, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research within the field.

  • Emerging Omics Technologies for Sustainable Agriculture

    • 1st Edition
    • Geerten W. Vuister + 3 more
    • English
    Emerging Omics Technologies for Sustainable Agriculture provides a comprehensive overview of the transformative potential of advanced tools such as AI, genomics and proteomics to ensure future agricultural production.The integration of genomics, transcriptomics, proteomics, and metabolomics has advanced the understanding of plant and microbial systems and the application of this knowledge has enabled precision farming, optimizing crop yield and minimizing environmental impact. There are unprecedented opportunities to enhance crop yields, improve pest and disease management, to optimize resource utilization and to mitigate environmental impacts. Through the use of advanced data analytics, machine learning, and predictive modeling, researchers can decipher complex biological processes and develop innovative solutions for agricultural challenges.Emerging Omics Technologies for Sustainable Agriculture explores the advancements in AI-driven omics technologies, such as genome editing, transcriptomics, and phenomics, and their applications in crop improvement, soil health monitoring, and precision agriculture.

  • Comprehensive Integrative Oncology

    • 1st Edition
    • Ting Bao
    • Suzanna Zick + 1 more
    • English
    Comprehensive Integrative Oncology is a vital resource for clinicians who seek to blend integrative therapies with conventional oncology care to enhance patient outcomes. This book, authored by experts in both conventional and integrative medicine, emphasizes a holistic approach to cancer treatment. It provides practical guidance on incorporating scientifically-backe... therapies like botanicals, supplements, mind-body practices, lifestyle changes, nutrition, and exercise into standard cancer care, all while prioritizing patient safety, prevention, and overall wellness. The book delves into the philosophy of integrative oncology, offers tools for practical application, and presents integrative strategies for cancer prevention and symptom management.Additiona... it explores the needs of special populations within oncology. It serves as an indispensable textbook for oncology researchers and practitioners who aim to provide holistic and patient-centered care.

  • Lipids and Membranes: Dynamics and Interorganelle Lipid Transport

    • 1st Edition
    • Volume 727
    • English
    Lipids and Membranes: Dynamics and Interorganelle Lipid Transport, Volume 728 covers lipids, a chemically diverse set of biological molecules subject to rapid metabolism and transport. This dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the book's chapters include topics such as Assay of phospholipid scrambling, Tracking lipid transport with bifunctional lipids, Tracking interorganelle lipid transport using genetically encoded mass tags, Molecular Dynamics Simulation of Lipid and Ligand Binding in ORD Domains, Imaging lipid droplet-organelle membrane contact sites using fluorogenic complementation, Studying interactions of amphipathic helices with lipid droplets, and more.Additional chapters cover Metabolic labeling of to trace changes in sphingolipid metabolism, Imaging intracellular lipid heterogeneity with fluorogen-activated coincidence sensing, Tagging lipoproteins in mycobacteria, Probes for studying sphingolipid dynamics, Measuring Flipper-TR Lifetime with Multiple Analysis Strategies, Reconstitution approaches to understanding cellular lipid dynamics, Prediction and characterization of the bacterial lipid handling machinery, From Molecular Dynamics to Cryo-EM: Imaging Liposomes in Silico, and much more.

  • Microglial Aging

    Basic, Translational and Clinical Advances
    • 1st Edition
    • Marie-Eve Tremblay
    • English
    Microglial Aging: Basic, Translational, and Clinical Advances explores groundbreaking research on microglial function in the context of aging. This comprehensive resource delves into the physiological roles of microglia, the effects of aging on their structure and activity, and their significance in age-related neurodegenerative diseases. With insights from basic, translational, and clinical studies, it provides a thorough understanding of microglial health and its impact on aging. The book discusses how lifestyle choices can enhance microglial functions and prevent neurodegenerative diseases. It covers both pharmacological and non-pharmacological approaches, such as the ketogenic diet, cannabinoids, psychedelics, and non-invasive vagal nerve stimulation.This text is invaluable for researchers and clinicians focused on improving the quality of life for an aging population.

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