Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.
Handbook of Milk Production, Quality and Nutrition emphasizes new applications to promote healthy milk production, processing, and product development in the milk industry, highlighting the role clean milk has in the prevention of health and disease. Sections cover the general aspects of milk production and its environmental impact on animal health, explain milk’s global nutritional appeal and its role as a source of both macro and micronutrients for human health, address issues of lactose intolerance and how this ailment is perceived globally, and discuss milk’s relevance on bone, ocular, and gut health.Finally, the book brings awareness to milk’s microbial pathogens, toxins, and heavy metals, and health concerns, while also updating on regulatory health and nutrition claims and recent legislative developments.
Emerging Trends and Applications of Deep Learning for Biomedical Data Analysis introduces the latest emerging trends and applications of deep learning in biomedical data analysis. The book delves into various use cases where deep learning is applied in industrial, social, and personal contexts within the biomedical domain. By gaining a comprehensive understanding of deep learning in biomedical data analysis, readers will develop the skills to critically evaluate research papers, methodologies, and emerging trends. In 14 chapters this book provides both insights into the fundamentals as the latest research trends in the applications of deep learning in biosciences. With several case studies and use cases it familiarizes the reader with a comprehensive understanding of deep learning algorithms, architectures, and methodologies specifically applicable to biomedical data analysis. This title is an ideal reference for researchers across the biomedical sciences.
An Overview of FDA Regulated Products: From Drugs and Cosmetics to Food and Tobacco, Second Edition is fully updated to reflect recent advances in science and technology and new laws and regulations. Breakthroughs in cellular and gene therapy, immunotherapy, precision medicine, and digital health are changing the face of healthcare and regulation. The updates brought about by the 21st Century Cures Act and subsequent PDUFA Reauthorizations, as well as signing into law the “Modernization of Cosmetic Regulation Act of 2022,” which will transform FDA’s oversight of cosmetics, are fully reflected in all chapters of the book.This book provides graduate students and industry professionals with comprehensive information on approval processes with the FDA and other country regulation organizations. Regulatory science professionals working with not only drugs, but biologics, medical devices, food and additives, cosmetics, veterinary products, and tobacco will benefit from this comprehensive overview of the regulatory environment.
Emerging Fuzzy Intelligent Systems for Smart Healthcare Management: Applications of Disc q-Rung Orthopair Fuzzy Sets presents comprehensive methodological frameworks and the latest empirical research findings concerning disc q-rung orthopair fuzzy operators, with a specific focus on their applications in smart technologies for healthcare management. The book solves a crucial problem by offering readers an invaluable opportunity to conduct a comparative analysis, contrasting the proposed methods with their existing knowledge base. Disc q-Rung Orthopair sets, being the generalization of q-Rung Orthopair fuzzy sets, which are, in turn, the generalization of Pythagorean fuzzy sets, extend the capabilities of handling uncertainty beyond conventional fuzzy sets.The authors strive to narrow the knowledge gap by clarifying the practical applications of disc q-rung orthopair fuzzy logic. In addition, it explores an enhanced version of q-Rung Orthopair Fuzzy Sets, specifically focusing on Disc q-Rung Orthopair Fuzzy Sets, introducing various types of operators. These operators play a crucial role in solving decision-making and optimization problems. A notable contribution is the development of a hybrid operator, termed as the Disc q-Rung Orthopair Fuzzy Hybrid Weighted Averaging/Geometric (D-qROFHWA/G) operator.
Nano-bioinoculants: Smart Tools for Modern Agriculture discusses the interactions between nanoparticles and soil–plants–microbiome systems in a single-volume book designed to guide improvements in sustainable agriculture i.e. plant production and soil health. Past practices for the application of pesticides and chemical fertilizers have reduced the beneficial microbial diversity and soil fertility essential for optimal crop yield and overall plant health. As a result, developing innovative approaches to plant/soil health maintenance, bioremediation process, and stress management is advancing. Plant protection methods are increasingly being tailored to improve sustainable precision results, reduce environmental impact, and to target specific plant health challenges. Nano-bioinoculants: Smart Tools for Modern Agriculture explains nanoparticles and beneficial microbes and their impact on soil microbiomes, soil fertility restoration, remediation of contaminated soil, and plant health. It also highlights nanoparticles and bioinoculants in stress management, plant growth, and productivity, as well as covering the potentially toxic effect of nanoparticles on humans and the environment. This volume in the Nanomaterial-Plant Interactions series explores the potential of nano-biotechnology for better agronomic performance and sustainability.
Gender Affirming Vaginoplasty is a novel reference of the latest research on those who present with Gender Dysphoria and desire surgery. The book describes the history of Gender Affirming Vaginoplasty (GAV), including social, legal, and ethical aspects of GAV, and explains updated Standards of Care. Users will find sections on preparation for surgery, different surgical techniques available (inclusive with the most recent developments), surgical results and complications, ways to solve complications, and finally, surgical procedures for persons who are requesting nonbinary genital surgery, and for those who are requesting reversal surgery.This is an unprecedented resource for all surgeons from various specialties already involved in gender-affirmative surgery and colleagues interested to gain state-of-the-art knowledge and experience in this field included plastic surgeons, urologists and gynecologists. Gender centers and trainees, scientists, researchers in transgender health, and organizations involved in trans health.
Translational Gastroenterology covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will learn important concepts, including case-control study, prospective cohort study, randomized trials, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in gastroenterology, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation.The book provides valuable discussions of the critical appraisal of published studies in gastroenterology, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every medical researcher or gastroenterologist who has ever had a good clinical idea but not the knowledge of how to test it.
Advanced Technologies for Coupled Enhancement of Gas-Solid Separation systematically explains the principles of cyclonic separation, the structural characteristics of equipment, the flow field in the separator, and new concepts and methods of coupled enhancement on cyclonic separation. The book provides basic theories and design methods as well as several new technologies and representative industrial application cases. This reference can be used by scholars, engineers, technicians, and students in the field of oil refining, petrochemical, coal chemical, and pan-chemical manufacturing.
Biodiversity, Bioengineering, and Biotechnology of Fungi examines various fungi genera and their biotechnological applications. The book covers the most common genera of fungi, their structure, their taxonomy, the maintenance and organization of a permanent study collection with associated databases, and their application in diverse sectors including industrial applications in the food, environment, bioenergy, biorefinery, and biopharma sectors. Compiled by an international team of fungal biologists, Biodiversity, Bioengineering, and Biotechnology of Fungi provides a wealth of information particularly on the diversity of fungal genera and their biotechnological contributions. The book is a valuable resource for scientists, researchers, health practitioners, nutritionists, industry professionals, advanced students, and all those who wish to broaden their knowledge in the allied field.